摘要:
An analyzer for performing automated assay testing. The analyzer includes a storage and conveyor system for conveying cuvettes to an incubation or processing conveyor, a storage and selection system for test sample containers, a storage and selection system for reagent containers, sample and reagent aspirating and dispensing probes, a separation system for separating bound from unbound tracer or labeled reagent, a detection system and date collection/processing system. All of the subunits of the machine are controlled by a central processing unit to coordinate the activity of all of the subunits of the analyzer. The analyzer is specifically suited for performing heterogeneous binding assay protocols, particularly immunoassays.
摘要:
A device for transferring, agitating, and sampling blood products sealed in tubes which are grouped together in cassettes wherein each cassette containing sample tubes is extracted from a storage receptacle by a moving loading and ejection carriage which shifts and positions it, using a retractable finger, in the cavity of a rotary carriage. The rotary carriage mixes the samples and stops so that sampling of tubes in the cassette can be performed by a sampling station which is movable in relation to the tubes temporarily immobilized in a vertical position with plugs facing downwards. The device is usable as a hematological analyzer.
摘要:
A cartridge feeder for dispensing a plurality of cartridges in single order and in upright position, each cartridge being cylindrical shape and having a top end tapering to an aperture therein and a substantially flat bottom end. A hopper stores a plurality of the cartridges and feeds those cartridges to a throat in a bridge to which the hopper is connected. The cartridge is passed through the bridge throat and to the throat of a shuttle. A pair of axially positioned pins with opposing cups close against the top end and the bottom end of the cartridge. The shuttle moves from a location underneath the bridge to a location over a chute. When the shuttle is over the chute, the first and second pins separate releasing the cartridge to fall through the chute. The first and second pins have a profile which engage the cartridge in a manner causing the bottom end of the cartridge to always drop first. The cartridge passes through the chute to a trap door. The trap door releases the cartridge to an opening in a carousel below, and positions the cartridge within the carousel by a flange mounted to the underneath side of the door.
摘要:
A small, inexpensive, and easy-to-use automated immunochemical anlayzer is provided. The automated immunochemical analyzer comprises at least one reaction plate of disposable type forming a plurality of containers in one body, a table that can be drawn out for mounting the reaction plates, a table can be drawn out for mounting specimen racks, a reagent thermostatic unit, a reaction thermostatic unit, a reaction plate holding part, an apparatus for aspirating and discharging sample liquid, and an XY moving part mounting the reaction plate holding part and the apparatus for aspirating and discharging sample liquid. First, by the XY moving part, the holding part holds the reaction plate before use from the table for mounting the reaction plates and moves up to the reaction thermostats unit. Consequently, by the XY moving part, the apparatus for aspirating and discharging sample liquid is moved reciprocally among the specimen rack, reagent thermostatic unit, and reaction thermostatic unit, thereby distributing specimens and reagents to the reaction plate. THe distributed liquid is kept in a thermostatic state, and shaken and agitated, thereby promoting the antigen-antibody reaction. The reaction liquid is sample by the apparatus for aspirating and discharging sample liquid, and is measured.
摘要:
An automated, continuous and random access analytical system, having apparatus and methodology capable of simultaneously performing multiple assays of liquid samples using different assay methodologies, and providing continuous and random access while performing a plurality of different assays on the same or different samples during the same time period, is disclosed. A method is also disclosed of operating an automated continuous and random access analytical system capable of simultaneously effecting multiple assays of a plurality of liquid samples wherein scheduling of various assays of the plurality of liquid samples is followed by creating a unit dose disposable and separately transferring a first liquid sample and reagents to a reaction vessel without initiation of an assay reaction sequence, followed by physical transfer of the unit dose disposable to a processing workstation, whereby a mixture of the unit dose disposable reagents and sample are achieved during incubation. The system is capable of performing more than one scheduled assay in any order, and assays where more than such scheduled assays are presented. The automated, continuous and random access analytical system is also capable of analyzing the incubated reaction mixtures independently and individually by at least two assay procedures.
摘要:
An analyzer system for automatic column chromatography includes chromatographic columns which are mounted in a rack. A drop removal mechanism system shakes the rack to transfer the last drop of eluate from the tip of a chromatographic column to a receptacle below the tip before the column is repositioned over another receptacle and another fluid or operation is introduced into the column. This prevents one eluate from contaminating another. The chromatographic column may have an upper end which is sealed by a foil member. During use, the foil member is ruptured by lowering a pressure cylinder with a seal-punching head against it. The pressure cylinder, which is part of the pressure tip unit, is then withdrawn so that fluid can be introduced into the column via the ruptured foil member. The pressure tip unit is then lowered into sealing engagement with the column so that pressure can be applied via a bore in the pressure cylinder. The column may also have a tip portion which is originally sealed by a removable cap. The rack has a plate with aperture that is configured to receive the tip portion of the column and to provide a bearing surface for a decapper member which removes the cap. This decapper member is lowered through the aperture, and the bearing surface forces it toward the tip portion so that the cap can be pushed off. After the chromatographic columns have been used, they can be regenerated for re-use without removing them from the rack.
摘要:
An automatic medical sampling device comprises a vacuum breaking needle for connecting the inside of a vacuum blood gathering tube with the air. An inserting needle has a length sufficient to be located at a position slightly below the lower end of the vacuum breaking needle at the highest position of the vacuum breaking needle. A container holder or maintainer has a bottom slope or projections for supporting a container, and a stirring device stops reciprocation of the stirring bar by detecting the position of the bar.
摘要:
The automatic sampling system includes a test apparatus for testing specific characteristics of a fluid withdrawn from a closed test tube. Stoppered test tubes are continuously and automatically delivered to the test apparatus by a conveyor system that includes a continuous linkage of test tube holders. The test tube holders have the capability of pivotal movement about a longitudinal axis of the test tube holders, and tilting movement wherein a longitudinal axis of one test tube holder tilts with respect to the longitudinal axis of another test tube holder in the linkage. The compound pivotal and tilting movement capability of the test tube holders in the linkage enable the linkage to be stacked in a fan-fold or Z-fold arrangement because of the flexible characteristics of the linkage. The linkage also has the capability of having one or more test tube holders tilted together at a group with respect to other test tube holders. Thus, the basis for a mixing operation of specific test tube holders is achieved. The conveyor system can be incorporated as a module of the test apparatus. An aspiration head for withdrawing fluid from individual stoppered test tubes in successive fashion as they are delivered by the conveyor system is also a modular addition to the test apparatus.
摘要:
A plurality of sealed blood sample tubes are housed in a rack and a plurality of these racks are vertically stacked, with the sample tubes lying horizontally. The racks are successively deposited onto a horizontal conveyor belt which is housed in and moves longitudinally on a table that rocks around its longitudinal axis to mix the samples in a semi-inverting mode as a rack is stepped from the stack to a sample aspiration station and/or thereat. The aspiration station preferably includes a sample segmenting and diluting valve and a sample identification reader. Aspiration is accomplished by pushing a sample tube partially out from the carrier rack and onto a seal piercing tip of the aspiration probe. The tube then is returned to the rack. The other tubes in that rack similarly are aspirated after the rack is stepped to align each tube with the aspiration probe, with table rocking and sampling mixing accompanying each advancing step of the rack. After a rack has advanced through the aspiration station, it is stacked out of the way.
摘要:
Apparatus for obtaining samples from specimens of blood or the like contained in a series of closed containers, which specimens include a plurality of particles such as cells. A pair of parallel feed screws moves the closed containers along a predetermined path to a sampling station and in one mode, a mixing mode, imparts motion to the closed containers while they are moved along the path to obtain a substantially uniform distribution of the particles contained therein. The apparatus includes a needle which penetrates the closed containers when they reach the sampling station to withdraw specimen samples from the containers. The apparatus includes a controller for tilting each closed container at the sampling station so that one end of the container is lower than the other end. The needle penetrates the lower end of the container.