公开(公告)号：US20180029731A1

公开(公告)日：2018-02-01

申请号：US15729066

申请日：2017-10-10

申请人： Roche Diagnostics Operations, Inc.

发明人： Markus Hegel

IPC分类号： B65B7/28 ,  G01N35/04

CPC分类号： B65B7/2878 ,  B65B7/2807 ,  G01N35/04 ,  G01N2001/002 ,  G01N2035/0403 ,  G01N2035/0405 ,  G01N2035/1093

摘要： A recapper for placing foils on laboratory sample containers is presented. The foils are brought on the sample container by a lever arrangement that is rotated around a vertical axis.

公开(公告)号：US09746487B2

公开(公告)日：2017-08-29

申请号：US14960719

申请日：2015-12-07

申请人： Roche Diagnostics Operations, Inc.

发明人： Christian Marty ,  Beat Rene Widmer ,  Markus Jeziorski

IPC分类号： G01N35/10 ,  G01N35/00 ,  G01N35/04

CPC分类号： G01N35/1011 ,  G01N35/0099 ,  G01N35/04 ,  G01N35/1081 ,  G01N2035/00089 ,  G01N2035/00287 ,  G01N2035/00326 ,  G01N2035/0403 ,  G01N2035/0427 ,  G01N2035/1051

摘要： A device for container storing is presented. The device comprises storage with at least one storing level including a pipetting storing level for fluid pipetting. Each storing level has storing positions having a container holder to detachably hold at least one container. A handler is movable with respect to the storage for transferring containers with respect to the storing positions. A storing position of the pipetting storing level includes a flat spring to bias a container against the container holder. The flat spring has a through hole to provide a pipette access to a lid of the container. A system for pipetting is also presented, comprising the device and a pipettor movable with respect to the pipetting storing level with at least one pipette for pipetting contained in a container stored in the pipetting storing level. The pipette has a pipette tip to penetrate a lid of the container.

公开(公告)号：US09731289B2

公开(公告)日：2017-08-15

申请号：US14653727

申请日：2013-12-18

申请人： EUROPEAN MOLECULAR BIOLOGY LABORATORY

发明人： Florent Cipriani ,  Jose Antonio Marquez

IPC分类号： B01L3/06 ,  B01L3/00 ,  G01N1/04 ,  G01N35/10 ,  G01N35/00 ,  G01N35/02 ,  C12M1/32 ,  C12M1/34 ,  C12M1/36 ,  G01N35/04

CPC分类号： B01L3/06 ,  B01L3/5085 ,  B01L3/50853 ,  B01L2200/025 ,  B01L2200/10 ,  B01L2300/044 ,  B01L2300/0893 ,  B01L2300/12 ,  B01L2300/16 ,  C12M23/12 ,  C12M41/36 ,  C12M41/48 ,  G01N1/04 ,  G01N35/0099 ,  G01N35/028 ,  G01N35/10 ,  G01N35/1079 ,  G01N2001/045 ,  G01N2035/0403

摘要： The present invention relates to the automation of incubation, processing, harvesting and analysis of samples in a multi-cell plate. In particular, a multi-cell plate including a body with a plurality of cells is presented. Furthermore, an automated crystal harvesting and processing system with a cutting unit, a fluid unit and a removing device is presented. The multi-cell plate further includes a sealing film for sealing the cells on a first side of the body and a sample film for sealing the cells on a second side of the body. The sample film is adapted for accommodating a biological material for crystallization. Furthermore, the sample film is of a thickness and composition that makes it compatible with x-rays and also with laser ablation. The design of the multi-cell plate and the automated crystal harvesting and processing system allows for several steps of incubation, processing, harvesting and analysis of the samples to be automated.

公开(公告)号：US20170120234A1

公开(公告)日：2017-05-04

申请号：US15336257

申请日：2016-10-27

申请人： Bruker BioSpin GmbH

发明人： Martin HOFMANN

IPC分类号： B01L3/02

CPC分类号： B01L3/021 ,  B01L3/0289 ,  B01L3/0293 ,  B01L3/0296 ,  B01L9/54 ,  B01L2200/025 ,  B01L2200/14 ,  B01L2300/044 ,  B01L2300/0672 ,  G01N35/1002 ,  G01N35/1079 ,  G01N2035/0403 ,  G01R33/302

摘要： A pipetting device (2) for removing fluid from a sample vessel (52) includes a pipetting needle (4) and an auxiliary cannula (18) for piercing a septum, designed to guide the pipetting needle axially through the auxiliary cannula. The pipetting device has a guide arm (6), on the lower end (10) of which is arranged an end plate (12) that is axially displaceable along the guide arm against a resilient resistance. A centering device (14) inserts into the end plate of the guide arm, and at least three centering fingers (26) with conical bevels (34) are constructed on the radial outside of the centering device, distributed around the circumference thereof, and forming a holding-down device for the sample vessel. The disclosed construction makes possible to reliably pierce the septum of a sample vessel and to easily pull the pipetting needle out of the septum again even with thin pipetting needles.

公开(公告)号：US20160161519A1

公开(公告)日：2016-06-09

申请号：US15043919

申请日：2016-02-15

申请人： Binergy Scientific, Inc.

发明人： Shelley Minteer ,  Vojtech Svoboda

IPC分类号： G01N35/02 ,  G01N33/02 ,  B01L3/00

CPC分类号： G01N35/026 ,  B01L3/502 ,  B01L2200/0668 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/168 ,  G01N27/02 ,  G01N33/02 ,  G01N2035/00534 ,  G01N2035/0091 ,  G01N2035/0403

摘要： A device, method and system for measuring analytes in a solution or suspension. The device includes a housing, a sample chamber, one or more pumps, one or more detectors, one or more stirrers, electrical contacts, a magnetic manipulator and a lid. A sample cartridge for a device that measures analytes, the cartridge comprising a first outer compartment, a second outer compartment, and a middle compartment, wherein the first outer compartment and the second outer compartment are interconnected to the middle compartment by channels.

摘要翻译： 用于测量溶液或悬浮液中分析物的装置，方法和系统。 该装置包括壳体，样品室，一个或多个泵，一个或多个检测器，一个或多个搅拌器，电触头，磁性操纵器和盖子。 一种用于测量分析物的装置的样品盒，所述盒包括第一外隔室，第二外隔室和中隔室，其中所述第一外隔室和所述第二外隔室通过通道互连到所述中隔室。

公开(公告)号：US09068956B2

公开(公告)日：2015-06-30

申请号：US13562992

申请日：2012-07-31

申请人： Kazuya Fukuda ,  Hiroki Koike ,  Hironori Katsumi ,  Takashi Yamato ,  Masayuki Ikeda ,  Tsuyoshi Fukuzaki ,  Daisuke Nakano ,  Masanori Imazu ,  Nobuhiro Kitagawa

发明人： Kazuya Fukuda ,  Hiroki Koike ,  Hironori Katsumi ,  Takashi Yamato ,  Masayuki Ikeda ,  Tsuyoshi Fukuzaki ,  Daisuke Nakano ,  Masanori Imazu ,  Nobuhiro Kitagawa

IPC分类号： G01N35/00 ,  G01N35/02 ,  G01N35/10

CPC分类号： G01N35/1065 ,  G01N35/00722 ,  G01N35/0092 ,  G01N35/025 ,  G01N35/026 ,  G01N35/1016 ,  G01N35/1079 ,  G01N35/1081 ,  G01N2035/00752 ,  G01N2035/00801 ,  G01N2035/0403 ,  G01N2035/0444 ,  G01N2035/1086

摘要： A specimen analyzing apparatus comprising: a detector for detecting component information regarding a component in a specimen contained in each of analyzing containers, the analyzing containers comprising first and second analyzing containers; an analyzing part for analyzing the component information detected by the detector; a transporting device for transporting specimen containers each containing a specimen, the specimen containers comprising first and second specimen containers; an operation mode selector for selecting one of a first operation mode and a second operation mode; a first supplying device for supplying the specimen of a first amount; a second supplying device for supplying the specimen of a second amount greater than the first amount; and a supply controller for controlling the first and second supplying devices in accordance with an operation mode selected by the operation mode selector, is disclosed. A specimen analyzing method is also disclosed.

摘要翻译： 一种样本分析装置，包括：检测器，用于检测包含在每个分析容器中的样本中的成分的成分信息，所述分析容器包括第一和第二分析容器; 用于分析由检测器检测到的分量信息的分析部件; 一个运送装置，用于运送每个包含试样的标本容器，该样本容器包括第一和第二标本容器; 操作模式选择器，用于选择第一操作模式和第二操作模式之一; 第一供给装置，其供给第一量的试样; 第二供给装置，用于向所述样本供给大于所述第一量的第二量; 以及用于根据由操作模式选择器选择的操作模式来控制第一和第二供应装置的供应控制器。 还公开了一种样本分析方法。

公开(公告)号：US20150031570A1

公开(公告)日：2015-01-29

申请号：US14376579

申请日：2013-02-04

申请人： Douglas Scientific, LLC

发明人： Paul Howard Wagner ,  Adnanul Haq ,  Richard Jerome Schoeneck

IPC分类号： G01N35/02 ,  G01N21/64

CPC分类号： G01N35/028 ,  G01N21/6452 ,  G01N35/00009 ,  G01N2035/00356 ,  G01N2035/00455 ,  G01N2035/0403 ,  G01N2035/0418 ,  G01N2035/0422 ,  G01N2035/0465 ,  G01N2201/0446

摘要： A high throughput biological sample processing system includes a sample carrier with a plurality of wells that progresses through the high throughput biological sample processing system. The system further includes a sample dispensing module, a reagent dispensing module, an accumulation/incubation module, and a detection module. The detection module employs an optical measuring device to encapsulate a biological sample in one of the plurality of wells of the sample carrier and detect energy from the chemistry of the biological sample to determine the amount of an analyte in the biological sample.

摘要翻译： 高通量生物样品处理系统包括具有穿过高通量生物样品处理系统的多个井的样品载体。 该系统还包括样品分配模块，试剂分配模块，累积/孵化模块和检测模块。 检测模块使用光学测量装置将生物样品包封在样品载体的多个孔中的一个孔中，并从生物样品的化学物质中检测能量，以确定生物样品中分析物的量。

公开(公告)号：US08153060B2

公开(公告)日：2012-04-10

申请号：US12200261

申请日：2008-08-28

申请人： Kenichiro Nishiki ,  Hajime Yamazaki

发明人： Kenichiro Nishiki ,  Hajime Yamazaki

IPC分类号： C12Q1/68

CPC分类号： B03C1/30 ,  B01L3/5021 ,  B03C1/288 ,  B03C2201/18 ,  G01N35/0098 ,  G01N35/025 ,  G01N2035/00495 ,  G01N2035/0403

摘要： An automatic analyzer includes a B/F separator including a reaction vessel holding unit provided with magnets disposed around a reaction vessel held on the reaction vessel holding unit and a rotating device for rotating the reaction vessel holding unit holding the reaction vessel about an axis of rotation aligned with the center axis of the reaction vessel or an axis of rotation parallel to and separated by a distance from the center axis of the reaction vessel. Both magnetic force and centrifugal force are exerted simultaneously on a specimen contained in a reaction vessel to capture magnetic particles contained in the liquid contained in the reaction vessel at a high capturing efficiency.

摘要翻译： 一种自动分析装置，包括：B / F分离器，包括：反应容器保持单元，设置有设置在保持在反应容器保持单元上的反应容器周围的磁体;旋转装置，用于使反应容器保持单元绕着旋转轴旋转 与反应容器的中心轴线对准或者与反应容器的中心轴线平行并与之隔开一段距离的旋转轴线。 将磁力和离心力同时施加在包含在反应容器中的样品上，以捕获效率高的速度捕获包含在反应容器中的液体中的磁性颗粒。

公开(公告)号：US20060234370A1

公开(公告)日：2006-10-19

申请号：US10553997

申请日：2004-04-22

申请人： Juha Korpinen ,  Jouko Viitanen

发明人： Juha Korpinen ,  Jouko Viitanen

IPC分类号： C12M1/34

CPC分类号： B01L3/50853 ,  B01L2300/042 ,  B01L2300/048 ,  B01L2300/0829 ,  C12M23/12 ,  C12M23/22 ,  C12M23/38 ,  C12M23/46 ,  C12M45/22 ,  G01N2035/0403

摘要： An analysis and culture apparatus including several wells, which have a cover that closes the well to form a closed space, as well as at least one inlet passage and one outlet passage for introducing matter to a closed space and for removing it from a closed space, respectively. The cover is formed as a separate cap, which can be removably attached to the well, with which the well can be closed, and to which the inlet passage and outlet passage are integrated.

摘要翻译： 包括几个井的分析和培养装置，其具有封闭井以形成封闭空间的盖，以及至少一个入口通道和一个出口通道，用于将物质引入封闭空间并将其从封闭空间中移出 ， 分别。 盖被形成为单独的盖，其可以可移除地附接到井，井可以通过该盖关闭，并且入口通道和出口通道被集成在该盖上。

公开(公告)号：US5236666A

公开(公告)日：1993-08-17

申请号：US833950

申请日：1992-02-11

申请人： William C. Hulette ,  Joseph G. Karp ,  Janet B. Callahan ,  Paul J. Braun ,  Stephen G. Richardson

发明人： William C. Hulette ,  Joseph G. Karp ,  Janet B. Callahan ,  Paul J. Braun ,  Stephen G. Richardson

IPC分类号： G01N35/00 ,  G01N35/02 ,  G01N35/04 ,  G01N35/10

CPC分类号： G01N35/00732 ,  G01N35/026 ,  G01N35/1072 ,  G01N2035/00376 ,  G01N2035/00435 ,  G01N2035/00752 ,  G01N2035/0403 ,  G01N2035/0487 ,  G01N2035/1025 ,  G01N2035/1076 ,  G01N2201/0407 ,  G01N35/1004 ,  G01N35/1079 ,  Y10S435/809 ,  Y10T436/113332 ,  Y10T436/2575

摘要： An arrangement is provided for temperature regulating a fluid sample in a cuvette transported through various stations of an automated system for optically monitoring the sample in the cuvette. A track guides the cuvette through the various stations of the optical monitoring system. The sample is in heat exchange relationship with the track by way of the cuvette. A drive unit drives the cuvette along the track. A cooling unit cools a first portion of the track. A heating unit heats a second portion. A heat flow restriction device restricts heat flow between the first and second portions of the track.

摘要翻译： 提供了一种用于温度调节通过自动化系统的各个站传输的比色皿中的流体样品的装置，用于光学监测比色皿中的样品。 轨道通过光学监控系统的各个站引导比色杯。 样品通过比色皿与轨道进行热交换关系。 驱动单元沿轨道驱动比色杯。 冷却单元冷却轨道的第一部分。 加热单元加热第二部分。 热流限制装置限制轨道的第一和第二部分之间的热流。