公开(公告)号：US20180361381A1

公开(公告)日：2018-12-20

申请号：US16058828

申请日：2018-08-08

申请人： IMEC VZW

发明人： Peter Peumans ,  Liesbet Lagae ,  Paolo Fiorini

IPC分类号： B01L3/00 ,  A61B5/15 ,  A61B5/151 ,  A61B5/157

摘要： The present disclosure relates to a fluid analyzing device that includes a sensing device for analyzing a fluid sample. The sensing device includes a microchip configured for sensing the fluid sample, and a closed micro-fluidic component for propagating the fluid sample to the microchip. The fluid sample can be provided to the micro-fluidic component via an inlet of the fluid analyzing device. And a vacuum compartment, which is air-tight connected to the sensing device, can create in the micro-fluidic component a suction force suitable for propagating the fluid sample through the micro-fluidic component.

公开(公告)号：US10154808B2

公开(公告)日：2018-12-18

申请号：US14251714

申请日：2014-04-14

申请人： Becton, Dickinson and Company

发明人： Gary D. Fletcher ,  Daniel J. Marchiarullo ,  Jamieson W. Crawford

IPC分类号： G01N33/49 ,  A61B5/15 ,  A61M1/34 ,  G01N1/28 ,  G01N1/40 ,  G01N1/34 ,  B01L3/00 ,  B04B7/08 ,  A61B5/151 ,  A61B5/157

摘要： A blood separation device that is adapted to receive a multi-component blood sample is disclosed. After collecting the blood sample, the blood separation device is able to separate a plasma portion from a cellular portion. After separation, the blood separation device is able to transfer the plasma portion of the blood sample to a point-of-care testing device. The blood separation device also provides a closed sampling and transfer system that reduces the exposure of a blood sample and provides fast mixing of a blood sample with a sample stabilizer. The blood separation device is engageable with a blood testing device for closed transfer of a portion of the plasma portion from the blood separation device to the blood testing device. The blood testing device is adapted to receive the plasma portion to analyze the blood sample and obtain test results.

公开(公告)号：US20180338713A1

公开(公告)日：2018-11-29

申请号：US14538096

申请日：2014-11-11

申请人： Sandia Corporation

发明人： Ronen Polsky ,  Philip Rocco Miller ,  Matthew W. Moorman ,  Susan M. Brozik ,  Ronald P. Manginell ,  David R. Wheeler ,  Thayne L. Edwards

IPC分类号： A61B5/1473 ,  A61B5/1459 ,  A61B5/00 ,  A61B5/145 ,  A61B5/157 ,  A61B5/155 ,  A61B5/15 ,  A61B10/00

摘要： The present invention is directed to devices and methods for detecting one or more markers in a sample. In particular, such devices integrate a plurality of hollow needles configured to extract or obtain a fluid sample from a subject, as well as transducers to detect a marker of interest (e.g., an electrolyte). In some embodiments, the needles are provided as a disposable cartridge.

公开(公告)号：US10136849B2

公开(公告)日：2018-11-27

申请号：US15341133

申请日：2016-11-02

申请人： Becton, Dickinson and Company

发明人： Craig A. Gelfand ,  Ashley Rachel Rothenberg ,  Bradley M. Wilkinson ,  Daniel J. Marchiarullo

IPC分类号： A61B5/00 ,  A61B5/15 ,  A61B5/151 ,  A61B5/157 ,  A61M1/34 ,  B01L3/00 ,  B04B7/08 ,  G01N1/28 ,  G01N1/34 ,  G01N1/40 ,  G01N33/49 ,  A61M1/36

摘要： A biological fluid collection device that is adapted to receive a blood sample having a cellular portion and a plasma portion is disclosed. After collecting the blood sample, the biological fluid collection device is able to transfer the blood sample to a point-of-care testing device or a biological fluid separation and testing device. After transferring the blood sample, the biological fluid separation and testing device is able to separate the plasma portion from the cellular portion and analyze the blood sample and obtain test results.

公开(公告)号：US20180325437A1

公开(公告)日：2018-11-15

申请号：US16036808

申请日：2018-07-16

申请人： DexCom, Inc.

发明人： Ying Li ,  Apurv Ullas Kamath ,  Richard C. Yang ,  Mark C. Brister

IPC分类号： A61B5/157 ,  C12Q1/00 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1473 ,  A61B5/1486 ,  A61B5/1495 ,  A61B5/15 ,  A61B5/155 ,  G16H40/40 ,  G16H10/40 ,  A61M5/14 ,  A61M5/168 ,  A61M5/172 ,  A61M5/142

CPC分类号： A61B5/157 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150992 ,  A61B5/155 ,  A61B5/412 ,  A61B5/4839 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/7275 ,  A61B5/743 ,  A61B2560/0223 ,  A61B2560/04 ,  A61B2562/085 ,  A61M5/14 ,  A61M5/16804 ,  A61M5/1723 ,  A61M2005/14296 ,  A61M2230/201 ,  C12Q1/001 ,  C12Q1/006 ,  G06F19/3468 ,  G16H10/40 ,  G16H20/17 ,  G16H40/40 ,  Y02A90/26

摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.

公开(公告)号：US10123728B2

公开(公告)日：2018-11-13

申请号：US15367726

申请日：2016-12-02

申请人： NP Medical Inc.

发明人： Luis Maseda ,  Todd Chelak ,  Nicholas Dennis ,  Ian Kimball

IPC分类号： A61M5/32 ,  A61M5/00 ,  A61B5/15 ,  A61M39/24 ,  A61M39/12 ,  A61M39/10 ,  A61M39/22 ,  A61B5/157 ,  A61M25/02 ,  A61M5/158

摘要： A catheter stabilization device includes a medical connector and a docking pod. The medical connector is configured to connect to a medical implement. The docking pod has an internal fluid path, a first opening, and an inlet opening. The first opening may be placed in fluid communication with a catheter. A docking pod adhesive layer that is located at least partially beneath at least a portion of the docking pod secures the docking pod to a patient. The device also includes an adherent substrate with a first film layer and at least a second film layer. The first and second film layers at least partially define a fluid pathway that extends through the adherent substrate and fluidly connects the medical connector and the inlet opening of the docking pod.

公开(公告)号：US20180317820A1

公开(公告)日：2018-11-08

申请号：US15908616

申请日：2018-02-28

申请人： ABBOTT DIABETES CARE INC.

发明人： Louis Pace ,  Peter G. Robinson ,  Udo Hoss ,  Samuel Mason Curry ,  Phillip William Carter ,  Vincent Michael DiPalma ,  Amit Mhatre ,  Jennifer Olson ,  Manuel Luis Miguel Donnay ,  Marc Barry Taub

IPC分类号： A61B5/145 ,  A61B5/15 ,  A61B5/00 ,  A61B5/157 ,  A61B5/151 ,  A61B50/30

CPC分类号： A61B5/14503 ,  A61B5/0004 ,  A61B5/1411 ,  A61B5/1451 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150305 ,  A61B5/150335 ,  A61B5/150358 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150748 ,  A61B5/15087 ,  A61B5/150877 ,  A61B5/15105 ,  A61B5/15144 ,  A61B5/157 ,  A61B5/6849 ,  A61B50/3001 ,  A61B2560/0443 ,  A61B2560/063 ,  A61B2562/242

摘要： Devices associated with on-body analyte sensor units are disclosed. These devices include any of packaging and/or loading systems, applicators and elements of the on-body sensor units themselves. Also, various approaches to connecting electrochemical analyte sensors to and/or within associated on-body analyte sensor units are disclosed. The connector approaches variously involve the use of unique sensor and ancillary element arrangements to facilitate assembly of separate electronics assemblies and sensor elements that are kept apart until the end user brings them together.

公开(公告)号：US20180310884A1

公开(公告)日：2018-11-01

申请号：US15828908

申请日：2017-12-01

申请人： Seventh Sense Biosystems, Inc.

发明人： Donald E. Chickering, III ,  Shawn Davis ,  Ramin Haghgooie ,  Howard Bernstein ,  Douglas A. Levinson ,  Mark Michelman

IPC分类号： A61B5/00 ,  A61B5/15 ,  A61B5/145 ,  A61B5/151 ,  A61B5/157

CPC分类号： A61B5/6849 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150221 ,  A61B5/150229 ,  A61B5/150236 ,  A61B5/150244 ,  A61B5/150297 ,  A61B5/150389 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150755 ,  A61B5/150969 ,  A61B5/150977 ,  A61B5/150984 ,  A61B5/15105 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15125 ,  A61B5/15144 ,  A61B5/15186 ,  A61B5/157 ,  A61B5/685

摘要： The present invention generally relates to systems and methods for delivering and/or withdrawing a substance or substances such as blood or interstitial fluid, from subjects, e.g., from the skin and/or from beneath the skin. In one aspect, the present invention is generally directed to devices and methods for withdrawing or extracting blood from a subject, e.g., from the skin and/or from beneath the skin, using devices containing a fluid transporter (for example, one or more microneedles), and a storage chamber having an internal pressure less than atmospheric pressure prior to receiving blood. In some cases, the device may be self-contained, and in certain instances, the device can be applied to the skin, and activated to withdraw blood from the subject. The device, or a portion thereof, may then be processed to determine the blood and/or an analyte within the blood, alone or with an external apparatus. For example, blood may be withdrawn from the device, and/or the device may contain sensors or agents able to determine the blood and/or an analyte suspected of being contained in the blood. Other aspects of the present invention are directed at other devices for withdrawing blood (or other bodily fluids, e.g., interstitial fluid), kits involving such devices, methods of making such devices, methods of using such devices, and the like.

公开(公告)号：US20180296149A1

公开(公告)日：2018-10-18

申请号：US16013258

申请日：2018-06-20

申请人： Smiths Medical ASD, Inc.

发明人： David Goral ,  Harsh Chheda ,  Jay Breindel ,  Gursel Akcay ,  James Muskatello ,  David Justmann

IPC分类号： A61B5/15 ,  A61M5/32 ,  A61M5/42 ,  A61M25/06 ,  A61M21/02 ,  A61B5/153 ,  A61M25/00 ,  A61B5/145 ,  A61B5/1477 ,  A61B5/157 ,  A61B17/132 ,  A61B10/00 ,  A61M39/22 ,  A61M21/00

摘要： A needle assembly. The needle assembly enabling the analysis of fluid trapped in a flashback chamber after an insertion needle has been inserted into a patient's vein.

公开(公告)号：US10052055B2

公开(公告)日：2018-08-21

申请号：US14072659

申请日：2013-11-05

申请人： DexCom, Inc.

发明人： Ying Li ,  Apurv Ullas Kamath ,  Richard C. Yang ,  Mark C. Brister

IPC分类号： A61B5/1495 ,  A61B5/157 ,  A61B5/00 ,  A61B5/145 ,  A61B5/1486 ,  C12Q1/00 ,  A61B5/1473 ,  A61B5/15 ,  A61B5/155 ,  A61M5/14 ,  A61M5/168 ,  A61M5/172 ,  A61M5/142 ,  G06F19/00 ,  G16H40/40

CPC分类号： A61B5/157 ,  A61B5/0031 ,  A61B5/14532 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/14546 ,  A61B5/14735 ,  A61B5/1486 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/15003 ,  A61B5/150992 ,  A61B5/155 ,  A61B5/412 ,  A61B5/4839 ,  A61B5/6848 ,  A61B5/6849 ,  A61B5/7275 ,  A61B5/743 ,  A61B2560/0223 ,  A61B2560/04 ,  A61B2562/085 ,  A61M5/14 ,  A61M5/16804 ,  A61M5/1723 ,  A61M2005/14296 ,  A61M2230/201 ,  C12Q1/001 ,  C12Q1/006 ,  G06F19/3468 ,  G16H10/40 ,  G16H20/17 ,  G16H40/40 ,  Y02A90/26

摘要： Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.