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22 条记录 (耗时 0.027 秒)

    ALIGNING CELLS ON WRINKLED SURFACE
    5.
    发明申请
    ALIGNING CELLS ON WRINKLED SURFACE 审中-公开
    皱纹表面上的标记细胞

    公开(公告)号：US20120129209A1

    公开(公告)日：2012-05-24

    申请号：US13257019

    申请日：2010-03-18

    申请人： Michelle Khine ,  Jesus Isaac Luna

    发明人： Michelle Khine ,  Jesus Isaac Luna

    IPC分类号： C12N5/071 ,  C12N5/079 ,  C12Q1/02 ,  C12N5/077

    CPC分类号： C12N5/0068 ,  C12N5/0657 ,  C12N2535/10 ,  G01N33/502

    摘要： A method is provided for preparing an aligned cell population comprising the culturing one or more cells on a surface having a texture, which texture has an average height of from about 100 nanometers to about 5 micrometers, thereby forming an aligned cell population on the textured surface. Also provided is a method to prepare the surface which method comprises the steps of: a) depositing a metal onto an unstressed or pre-stressed thermoplastic material; b) reducing the surface area of the receptive material by at least about 60%; and c) preparing the surface via lithography.

    摘要翻译： 提供了一种用于制备排列的细胞群的方法，其包括在具有纹理的表面上培养一个或多个细胞，该纹理的平均高度为约100纳米至约5微米，从而在纹理表面上形成排列的细胞群 。 还提供了一种制备表面的方法，该方法包括以下步骤：a）将金属沉积到未受应力或预应力的热塑性材料上; b）将接收材料的表面积减少至少约60％; 和c）通过光刻制备表面。

    Photolithography on shrink film
    6.
    发明授权
    Photolithography on shrink film 有权

    公开(公告)号：US09625819B2

    公开(公告)日：2017-04-18

    申请号：US13481653

    申请日：2012-05-25

    申请人： Michelle Khine ,  Shreshta Jayadev

    发明人： Michelle Khine ,  Shreshta Jayadev

    IPC分类号： G01B11/04 ,  G03F7/20 ,  G03F7/00

    CPC分类号： G03F7/20 ,  G03F7/0005 ,  Y10T428/24479

    摘要： Provided are methods of preparing a plurality of extrusions, comprising (a) shrinking a transparent first thermoplastic material comprising a plurality of non-transparent marks, (b) lithographically transferring the pattern of the shrunk non-transparent marks to a layer of photoresist deposited on a second thermoplastic material, and (c) shrinking the second thermoplastic material, thereby generating a plurality of extrusions on the shrunk second thermoplastic material.

    HONEYCOMB SHRINK WELLS FOR STEM CELL CULTURE
    8.
    发明申请
    HONEYCOMB SHRINK WELLS FOR STEM CELL CULTURE 审中-公开
    HONEYCOMB收缩细胞干细胞培养

    公开(公告)号：US20120129208A1

    公开(公告)日：2012-05-24

    申请号：US13257016

    申请日：2010-03-17

    申请人： Michelle Khine ,  Diep Nguyen

    发明人： Michelle Khine ,  Diep Nguyen

    IPC分类号： C12Q1/02 ,  C12N5/07 ,  C12N5/071 ,  B44C1/22 ,  B05D5/00 ,  C23C16/44 ,  B05D3/12 ,  C12N5/00 ,  C12M1/00

    CPC分类号： C12M23/20 ,  B01L3/5085 ,  B01L2200/12 ,  C12M23/12

    摘要： This invention provides a microwell array having a plurality of microwells on a hydrophobic surface wherein the microwells each is substantially proximate to each of its adjacent microwells, as well as methods to prepare arrays. Also provided is a plate that comprises at least one microarray, at least one input channel, at least one output channel, and a channel connecting the input and output channel.

    摘要翻译： 本发明提供了一种在疏水表面上具有多个微孔的微孔阵列，其中微孔各自基本上邻近其每个相邻的微孔，以及制备阵列的方法。 还提供了一种板，其包括至少一个微阵列，至少一个输入通道，至少一个输出通道和连接输入和输出通道的通道。