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12 条记录 (耗时 0.027 秒)

    MONOLITHIC ELECTROKINETIC PUMP FABRICATION
    1.
    发明申请
    MONOLITHIC ELECTROKINETIC PUMP FABRICATION 有权
    单相电动泵制造

    公开(公告)号：US20100168457A1

    公开(公告)日：2010-07-01

    申请号：US12447477

    申请日：2007-11-06

    申请人： Moon Chul Jung ,  Edouard S. P. Bouvier ,  Steven A. Cohen ,  Hua Yang

    发明人： Moon Chul Jung ,  Edouard S. P. Bouvier ,  Steven A. Cohen ,  Hua Yang

    IPC分类号： C07F7/21

    CPC分类号： F04B19/006 ,  C08G77/16 ,  C08G77/26 ,  C08G77/388 ,  C08K5/09 ,  C08K5/544 ,  C08L83/04 ,  G01N2030/326 ,  G01N2030/528

    摘要： High-pressure electrokinetic (“EK”) pumps comprising a hybrid monolith provide a high surface charge density and a continuous stable skeleton morphology with micrometer- sized through-pores. The hybrid monolith of the subject invention has superior mechanical strength and better stability in comparison to prior art monoliths with equivalent mechanical stability. The surface charge of the hybrid monolith can be modified and/or made stable by the use of different chemical reagents. The chemical reagents and resulting modification to the monolith serves to expand the usefulness of the hybrid monolith to a variety of pumping applications including chip-based systems and other applications where the ability to pump an acidic solution is required.

    摘要翻译： 包括混合整料的高压电动（“EK”）泵提供高表面电荷密度和具有微米尺寸通孔的连续稳定的骨架形态。 与具有等效机械稳定性的现有技术的整料相比，本发明的混合整料具有优异的机械强度和更好的稳定性。 可以通过使用不同的化学试剂来改变和/或制备稳定的混合整料的表面电荷。 化学试剂和对整料的所得改性用于将混合整料的有用性扩展到各种泵送应用，包括基于芯片的系统和需要泵送酸性溶液的能力的其它应用。

    Monolithic electrokinetic pump fabrication
    2.
    发明授权
    Monolithic electrokinetic pump fabrication 有权
    单片电动泵制造

    公开(公告)号：US08680311B2

    公开(公告)日：2014-03-25

    申请号：US12447477

    申请日：2007-11-06

    申请人： Moon Chul Jung ,  Edouard S. P. Bouvier ,  Steven A. Cohen ,  Hua Yang

    发明人： Moon Chul Jung ,  Edouard S. P. Bouvier ,  Steven A. Cohen ,  Hua Yang

    IPC分类号： C07F7/00

    CPC分类号： F04B19/006 ,  C08G77/16 ,  C08G77/26 ,  C08G77/388 ,  C08K5/09 ,  C08K5/544 ,  C08L83/04 ,  G01N2030/326 ,  G01N2030/528

    摘要： High-pressure electrokinetic (“EK”) pumps comprising a hybrid monolith provide a high surface charge density and a continuous stable skeleton morphology with micrometer-sized through-pores. The hybrid monolith of the subject invention has superior mechanical strength and better stability in comparison to prior art monoliths with equivalent mechanical stability. The surface charge of the hybrid monolith can be modified and/or made stable by the use of different chemical reagents. The chemical reagents and resulting modification to the monolith serves to expand the usefulness of the hybrid monolith to a variety of pumping applications including chip-based systems and other applications where the ability to pump an acidic solution is required.

    摘要翻译： 包括混合整料的高压电动（“EK”）泵提供高表面电荷密度和具有微米尺寸通孔的连续稳定的骨架形态。 与具有等效机械稳定性的现有技术的整料相比，本发明的混合整料具有优异的机械强度和更好的稳定性。 可以通过使用不同的化学试剂来改变和/或制备稳定的混合整料的表面电荷。 化学试剂和对整料的所得改性用于将混合整料的有用性扩展到各种泵送应用，包括基于芯片的系统和需要泵送酸性溶液的能力的其它应用。

    APPARATUS AND METHODS FOR PREPARATION AND ANALYSIS OF DRIED SAMPLES OF A BIOLOGICAL FLUID
    6.
    发明申请
    APPARATUS AND METHODS FOR PREPARATION AND ANALYSIS OF DRIED SAMPLES OF A BIOLOGICAL FLUID 审中-公开
    生物流体干燥样品的制备与分析装置及方法

    公开(公告)号：US20130068043A1

    公开(公告)日：2013-03-21

    申请号：US13698164

    申请日：2011-05-31

    申请人： Moon Chul Jung ,  Edouard S. P. Bouvier ,  Geoff C. Gerhardt

    发明人： Moon Chul Jung ,  Edouard S. P. Bouvier ,  Geoff C. Gerhardt

    IPC分类号： B01L3/00

    CPC分类号： C02F1/004 ,  C02F1/281 ,  C02F1/283 ,  C02F2101/32 ,  C02F2201/007 ,  C02F2201/008

    摘要： Described is a device for collecting a fluid sample, such as a biological fluid sample. The device includes a planar collection substrate having an absorbent material. The planar collection substrate includes an impermeable region and a sample collection region. The impermeable region is impermeable to the fluid sample and is embedded in the planar collection substrate in a spatial pattern. The sample collection region is in an area excluded from the spatial pattern and has a shape and a size defined by the spatial pattern. The sample collection region is configured to receive a known volume of the fluid sample. In an alternative form, the device includes a sample collection element disposed in an impermeable planar holder and, in another alternative form, the device includes an absorbent material disposed inside an impermeable tube wall.

    摘要翻译： 描述了用于收集诸如生物流体样品的流体样品的装置。 该装置包括具有吸收材料的平面收集基板。 平面收集基板包括不可渗透区域和样品收集区域。 不渗透区域对于流体样品是不可渗透的，并以空间图案嵌入在平面收集基板中。 样本收集区域在从空间图案排除的区域中，并且具有由空间图案定义的形状和尺寸。 样品收集区域被配置为接收已知体积的流体样品。 在替代形式中，该装置包括设置在不可渗透的平面保持器中的样品收集元件，并且在另一替代形式中，该装置包括设置在不可渗透管壁内部的吸收材料。

    Immobilized enzymatic reactor
    7.
    发明授权
    Immobilized enzymatic reactor 有权

    公开(公告)号：US09890411B2

    公开(公告)日：2018-02-13

    申请号：US13985900

    申请日：2012-02-13

    申请人： Joomi Ahn ,  Moon Chul Jung ,  Kevin D. Wyndham

    发明人： Joomi Ahn ,  Moon Chul Jung ,  Kevin D. Wyndham

    IPC分类号： C12Q1/37 ,  C12N11/06 ,  C12N11/14 ,  C12M1/40 ,  C12M1/34 ,  C12Q1/48

    CPC分类号： C12Q1/37 ,  C12M21/18 ,  C12M41/40 ,  C12N11/06 ,  C12N11/14 ,  C12Q1/48

    摘要： An immobilized enzymatic reactor can include a wall defining a chamber having an inlet and an outlet; a solid stationary phase covalently linked to an enzyme and disposed within the chamber; and a pressure modulator in fluid communication with the chamber and adapted to support continuous flow of a liquid sample comprising a polymer analyte through the inlet, over the solid stationary phase, and out of the outlet under a pressure between about 2,500 and 35,000 psi. In one example, the solid stationary phase includes inorganic/organic hybrid particles in an ultra performance liquid chromatography system, the enzyme is a protease, and the polymer analyte is a polypeptide. The immobilized enzymatic reactor can prepare an analyte for applications such as for hydrogen deuterium exchange mass spectrometry.

    SPECTROSCOPIC SAMPLE INSPECTION FOR AUTOMATED CHROMATOGRAPHY
    9.
    发明申请
    SPECTROSCOPIC SAMPLE INSPECTION FOR AUTOMATED CHROMATOGRAPHY 审中-公开
    用于自动色谱的光谱样品检测

    公开(公告)号：US20130327129A1

    公开(公告)日：2013-12-12

    申请号：US13980972

    申请日：2012-02-14

    申请人： Moon Chul Jung

    发明人： Moon Chul Jung

    IPC分类号： G01N30/00 ,  G01N21/65 ,  G01J3/46

    CPC分类号： G01N30/00 ,  G01J3/46 ,  G01N21/65 ,  G01N30/74

    摘要： A method and a system for generating an extraction sample from a dried sample spot. The method includes acquiring a spectroscopic image of an analyte in the spot. The spectroscopic image includes information on a spatial distribution of the analyte. A region of the spot to be extracted is determined from the spectroscopic image and an extraction sample is generated from the determined region. In other embodiments, the method and system are based on acquiring a spectroscopic measurement of an analyte in the dried sample spot, determining a quantity of the analyte in the spot based on the spectroscopic measurement and determining a volume of an extraction solvent for creating an extraction sample from the spot. The determined volume is based on the determined quantity of the analyte and a detection characteristic of an analytical measurement system. In other embodiments, the method is applied to solid samples.

    摘要翻译： 一种用于从干燥的样品斑点产生提取样品的方法和系统。 该方法包括获取斑点中分析物的分光图像。 分光图像包括关于分析物的空间分布的信息。 从分光图像确定要提取的光斑的区域，并且从确定的区域产生提取样品。 在其他实施方案中，该方法和系统基于获取干燥样品斑点中的分析物的光谱测量，基于光谱测量确定斑点中的分析物的量并确定用于产生提取的提取溶剂的体积 从现场抽样。 所确定的体积基于所确定的分析物的量和分析测量系统的检测特性。 在其他实施方案中，将该方法应用于固体样品。