Plasmon resonance (PR) system, instrument, cartridge, and methods and configurations thereof

    公开(公告)号:US11278890B2

    公开(公告)日:2022-03-22

    申请号:US17265162

    申请日:2019-08-06

    摘要: A plasmon resonance system, instrument, cartridge, and methods for analysis of analytes is disclosed. A PR system is provided that may include a DMF-LSPR cartridge that may support both digital microfluidic (DMF) capability and localized surface plasmon resonance (LSPR) capability for analysis of analytes. In some examples, the DMF portion of the DMF-LSPR cartridge may include an electrode arrangement for performing droplet operations, whereas the LSPR portion of the DMF-LSPR cartridge may include an LSPR sensor. In other examples, the LSPR portion of the DMF-LSPR cartridge may include an in-line reference channel, wherein the in-line reference channel may be a fluid channel including at least one functionalized LSPR sensor (or sample spot) and at least one non-functionalized LSPR sensor (or reference spot). Additionally, methods of using the PR system for analysis of analytes are provided.

    Swivel mount for centrifugal microfluidic chip

    公开(公告)号:US11071985B2

    公开(公告)日:2021-07-27

    申请号:US15313961

    申请日:2015-05-26

    IPC分类号: B01L9/00 B04B5/04 G01N35/00

    摘要: A centrifugal microfluidic chip mounting, kit and method include a swivel joint permitting a chip to rotate about an axis of the chip in a plane swept by a centrifuge, and a force applicator for controlling an angle of the swivel and for applying a force in proportion to a rotational rate of the centrifuge. The mounting includes: a blade part (18) that couples to, or defines, a blade (10) of a centrifuge at a radial distance from a centrifuge axis (12); a chip part (20) that holds the chip at an orientation having a normal not perpendicular to the axis; a one degree of freedom (DoF) joint (16) between the blade part and the chip part; and a force applicator (28) which bears on the chip part at a fixed set of one or more points, which do not surround, and are not surrounded by, the joint.

    POLYMER FILM-METAL COMPOSITES
    6.
    发明申请

    公开(公告)号:US20200223999A1

    公开(公告)日:2020-07-16

    申请号:US16651018

    申请日:2018-09-25

    摘要: The present application relates to polymer film-metal composites, to methods of preparing polymer film-metal composites and to uses of such composites. The metal can be in the form of a nanoparticle or a film. The methods comprise depositing on a surface, a composition comprising: a cationic metal precursor; a polymer film precursor that comprises a plurality of photopolymerizable groups; and a photoreducer-photoinitiator; then irradiating the composition under conditions to simultaneously reduce the cationic metal and polymerize the photopolymerizable groups to obtain the composite on the surface.