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    Determination of dynamic DRRs
    5.
    发明授权
    Determination of dynamic DRRs 有权

    公开(公告)号：US12118648B2

    公开(公告)日：2024-10-15

    申请号：US18309968

    申请日：2023-05-01

    申请人： Brainlab AG

    发明人： Kajetan Berlinger ,  Birte Domnik ,  Elisa Garcia Corisco ,  Pascal Bertram

    IPC分类号： G06T11/00 ,  A61B6/00 ,  A61B6/03 ,  A61B6/12 ,  A61N5/10 ,  G06T7/00 ,  G06T7/20 ,  G16H50/50

    CPC分类号： G06T11/003 ,  A61B6/032 ,  A61B6/12 ,  A61B6/486 ,  A61B6/5223 ,  A61B6/5288 ,  A61N5/1037 ,  A61N5/1049 ,  G06T7/0012 ,  G06T7/20 ,  G06T11/008 ,  G16H50/50 ,  A61N2005/1062 ,  G06T2207/10076 ,  G06T2207/10081 ,  G06T2207/10124 ,  G06T2207/30241 ,  G06T2211/412

    摘要： A computer implemented method for determining a two dimensional DRR referred to as dynamic DRR based on a 4D-CT, the 4D-CT describing a sequence of three dimensional medical computer tomographic images of an anatomical body part of a patient, the images being referred to as sequence CTs, the 4D-CT representing the anatomical body part at different points in time, the anatomical body part comprising at least one primary anatomical element and secondary anatomical elements, the computer implemented method comprising the following steps: acquiring the 4D-CT; acquiring a planning CT, the planning CT being a three dimensional image used for planning of a treatment of the patient, the planning CT being acquired based on at least one of the sequence CTs or independently from the 4D-CT, acquiring a three dimensional image, referred to as undynamic CT, from the 4D-CT, the undynamic CT comprising at least one first image element representing the at least one primary anatomical element and second image elements representing the secondary anatomical elements; acquiring at least one trajectory, referred to as primary trajectory, based on the 4D-CT, the at least one primary trajectory describing a path of the at least one first image element as a function of time; acquiring trajectories of the second image elements, referred to as secondary trajectories, based on the 4D-CT; for the image elements of the undynamic CT, determining trajectory similarity values based on the at least one primary trajectory and the secondary trajectories, the trajectory similarity values respectively describing a measure of similarity between a respective one of the secondary trajectories and the at least one primary trajectory; determining the dynamic DRR by using the determined trajectory similarity values, and, in case the planning CT is acquired independently from the 4D-CT, further using a transformation referred to as planning transformation from the undynamic CT to the planning CT, at least a part of image values of image elements of the dynamic DRR being determined by using the trajectory similarity values.

    DESIGN AND MANUFACTURE OF ORTHODONTIC APPLIANCES
    7.
    发明公开
    DESIGN AND MANUFACTURE OF ORTHODONTIC APPLIANCES 审中-公开

    公开(公告)号：US20240325119A1

    公开(公告)日：2024-10-03

    申请号：US18621777

    申请日：2024-03-29

    申请人： ArchForm, Inc.

    发明人： Martin Martz ,  Andrew Martz

    IPC分类号： A61C7/28 ,  A61C7/00 ,  G16H50/50

    CPC分类号： A61C7/282 ,  A61C7/002 ,  G16H50/50

    摘要： A system may display a user interface depicting a model of a patient's teeth and the patient's palate and/or the buccal shelf area. The palate and/or the buccal shelf area depict one or more implants. The system determines a non-moveable zone about the model via receiving a user input identifying the one or more non-moveable zones. The system generates multiple electronic versions of aligners configured to fit over the one or more implants and the patient's teeth. Wearing of successive aligners cause the patient's teeth to move in a direction toward a correction, while the aligners have non-moveable zones that remain in a fixed location in relationship to the one or more implants.

    Techniques for conducting virtual clinical trials
    9.
    发明授权
    Techniques for conducting virtual clinical trials 有权

    公开(公告)号：US12106831B2

    公开(公告)日：2024-10-01

    申请号：US17668418

    申请日：2022-02-10

    申请人： Fresenius Medical Care Holdings, Inc.

    发明人： Doris H. Fuertinger ,  Alice Topping ,  Franz Kappel ,  Stephan Thijssen ,  Peter Kotanko

    IPC分类号： G16H10/20 ,  G16H50/50 ,  G16H50/70

    CPC分类号： G16H10/20 ,  G16H50/50 ,  G16H50/70

    摘要： Techniques and apparatus for generating, performing, and evaluating virtual clinical trials that include clinic modules to represent real-world operational aspects of trial entities are described. In one embodiment, for example, an apparatus may include at least one memory, and logic coupled to the at least one memory. The logic may be configured to generate a plurality of avatars configured to model a health condition associated with a population of patients, and to perform a virtual clinical trial to simulate a course of treatment for the plurality of avatars, the virtual clinical trial to include at least one clinic module associated with at least one event and a probability for the at least one event, the at least one event to model an operational aspect of an entity of the virtual clinical trial. Other embodiments are described.