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公开(公告)号:US12114997B2
公开(公告)日:2024-10-15
申请号:US17831715
申请日:2022-06-03
Applicant: North Carolina State University
Inventor: Alper Bozkurt , James P. Dieffenderfer
IPC: A61B5/00 , A61B5/0205 , A61B5/024 , A61B5/1455 , A61B5/022 , A61B5/08 , A61M21/00
CPC classification number: A61B5/4815 , A61B5/0075 , A61B5/0205 , A61B5/02416 , A61B5/14553 , A61B5/14557 , A61B5/4812 , A61B5/4857 , A61B5/688 , A61B5/02225 , A61B5/02433 , A61B5/0816 , A61B2562/0238 , A61M2021/0044
Abstract: Systems and methods for monitoring sleep are disclosed. According to an aspect, a method includes emitting light into tissue. The method also includes detecting light backscattered from the tissue. Further, the method includes determining a sleep pattern based on the backscattered light.
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公开(公告)号:US20230371981A1
公开(公告)日:2023-11-23
申请号:US18138978
申请日:2023-04-25
Applicant: The Regents of the University of California
Inventor: Timothy L. Hanson , Michel M. Maharbiz , Philip N. Sabes
CPC classification number: A61B17/3468 , A61N5/0601 , A61N5/0622 , A61N1/0531 , A61N1/0534 , A61B5/293 , A61B5/0084 , A61B5/1473 , A61B5/688 , A61B5/6882 , A61N1/0539 , A61B2017/00526
Abstract: Methods, systems, and compositions are provided for implanting an implantable device into a biological tissue (e.g., muscle, brain). A subject implantable device includes: (i) a biocompatible substrate, (ii) a conduit (e.g., an electrode, a waveguide) that is disposed on the biocompatible substrate, and (iii) an engagement feature (e.g., a loop) for reversible engagement with an insertion needle. The biocompatible substrate can be flexible (e.g., can include polyimide). The implantable device is implanted using an insertion needle that includes an engagement feature corresponding to the engagement feature of the implantable device. To implant, an implantable device is reversibly engaged with an insertion needle, the device-loaded insertion needle is inserted into a biological tissue (e.g., to a desired depth), and the insertion needle is retracted, thereby disengaging the implantable device from the insertion needle and allowing the implantable device to remain implanted in the biological tissue.
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公开(公告)号:US11707213B2
公开(公告)日:2023-07-25
申请号:US16944734
申请日:2020-07-31
Applicant: BIONIME CORPORATION
Inventor: Chun-Mu Huang , Chieh-Hsing Chen
CPC classification number: A61B5/14532 , A61B5/0004 , A61B5/14503 , A61B5/688 , A61B2562/166 , A61B2562/226 , A61B2562/227
Abstract: A physiological signal monitoring device includes a sensing member and a transmitter connected to the sensing member and including a circuit board that has electrical contacts, and a connecting port, which includes a socket communicated to the circuit board and a plurality of conducting springs disposed at two opposite sides of the socket. The sensing member is removably inserted into the socket. The conducting springs are electrically connected to the electrical contacts and the sensing member for enabling electric connection therebetween. Each of the conducting springs is frictionally rotated by the sensing member during insertion of the sensing member into the socket and removal of the sensing member from the socket.
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公开(公告)号:US11642055B2
公开(公告)日:2023-05-09
申请号:US17892707
申请日:2022-08-22
Applicant: DexCom, Inc.
Inventor: Jason Halac , John Michael Gray , Justen Deering England , Paul V. Neale , Jennifer Blackwell , Maria Noel Brown Wells , Kenneth Pirondini
IPC: A61B5/1486 , A61B5/145 , A61B5/00
CPC classification number: A61B5/14865 , A61B5/14532 , A61B5/14546 , A61B5/688 , A61B5/6832 , A61B5/6848 , A61B5/6849 , A61B5/68335 , A61B2560/063
Abstract: Systems for applying a transcutaneous monitor to a person can include a telescoping assembly, a sensor, and a base with adhesive to couple the sensor to skin. The sensor can be located within the telescoping assembly while the base protrudes from a distal end of the system. The system can be configured to couple the sensor to the base by compressing the telescoping assembly.
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公开(公告)号:US20190246988A1
公开(公告)日:2019-08-15
申请号:US16262945
申请日:2019-01-31
Applicant: Industrial Technology Research Institute
Inventor: Ming-Huan Yang , Cheng-Chung Lee , Shih-Kuang Chiu , Kuang-Ching Fan
IPC: A61B5/00 , A61B5/0205 , A61B5/0424 , A61B5/024
CPC classification number: A61B5/721 , A61B5/0002 , A61B5/02055 , A61B5/02405 , A61B5/02438 , A61B5/04004 , A61B5/04012 , A61B5/0424 , A61B5/08 , A61B5/6833 , A61B5/688 , A61B5/743
Abstract: A physiological signal correction device, a correction method, and a wearable device with a correction function are provided. The physiological signal correction device includes a physiological signal sensor, a warping sensor, and a signal processing device. The physiological signal sensor is attached to an object to be detected to obtain a physiological signal value from at least one sensing electrode. The warping sensor is disposed on the physiological signal sensor and detects whether a warping condition of the physiological signal sensor with respect to the object to be detected occurs. The signal processing device corrects the physiological signal value provided by the physiological signal sensor according to the warping condition. The warping condition is caused by a distance between a part of the sensing electrode and the object to be detected or a change in a contact area between a part of the sensing electrode and the object to be detected.
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公开(公告)号:US20180344186A1
公开(公告)日:2018-12-06
申请号:US16041140
申请日:2018-07-20
Applicant: STMicroelectronics, Inc.
Inventor: John H. ZHANG
IPC: A61B5/04 , A61B5/00 , B82Y30/00 , G01N27/414
CPC classification number: A61B5/04001 , A61B5/6877 , A61B5/688 , B82Y30/00 , G01N27/4145 , Y10T29/4913
Abstract: It is recognized that, because of its unique properties, graphene can serve as an interface with biological cells that communicate by an electrical impulse, or action potential. Responding to a sensed signal can be accomplished by coupling a graphene sensor to a low power digital electronic switch that is activatable by the sensed low power electrical signals. It is further recognized that low power devices such as tunneling diodes and TFETs are suitable for use in such biological applications in conjunction with graphene sensors. While tunneling diodes can be used in diagnostic applications, TFETs, which are three-terminal devices, further permit controlling the voltage on one cell according to signals received by other cells. Thus, by the use of a biological sensor system that includes graphene nanowire sensors coupled to a TFET, charge can be redistributed among different biological cells, potentially with therapeutic effects.
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公开(公告)号:US20170245798A1
公开(公告)日:2017-08-31
申请号:US15592451
申请日:2017-05-11
Applicant: TERUMO KABUSHIKI KAISHA
Inventor: Takahiro OHKOSHI
IPC: A61B5/00 , A61B5/1486 , A61B5/145 , A61B17/34 , A61M5/158
CPC classification number: A61B5/6849 , A61B5/0031 , A61B5/14503 , A61B5/14532 , A61B5/14865 , A61B5/688 , A61B5/72 , A61B17/3468 , A61B2560/063 , A61B2562/225 , A61M5/158 , A61M2005/1585
Abstract: A method involves supporting both a sensor which measures biological information and an insertion needle at a location proximally spaced from the distal end portion of a device body. The sensor includes a detector which detects a body fluid component of the patient used to measure the biological information, and a signal processor which is attached to the device body and which processes a signal including the biological information. The method also involves moving the sensor and the insertion needle in the distal direction so that the detector and a portion of the insertion needle protrude distally beyond the distal end portion of the device body, separating the insertion needle from the sensor by moving the insertion needle relative to the sensor toward a proximal direction, and electrically connecting the sensor and the signal processor by operation of the device body after the insertion needle is separated from the sensor.
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公开(公告)号:US09730596B2
公开(公告)日:2017-08-15
申请号:US13931138
申请日:2013-06-28
Applicant: STMicroelectronics, Inc.
Inventor: John H. Zhang
IPC: A61B5/04 , A61B5/00 , A61N1/00 , G01N27/414 , B82Y30/00
CPC classification number: A61B5/04001 , A61B5/6877 , A61B5/688 , B82Y30/00 , G01N27/4145 , Y10T29/4913
Abstract: It is recognized that, because of its unique properties, graphene can serve as an interface with biological cells that communicate by an electrical impulse, or action potential. Responding to a sensed signal can be accomplished by coupling a graphene sensor to a low power digital electronic switch that is activatable by the sensed low power electrical signals. It is further recognized that low power devices such as tunneling diodes and TFETs are suitable for use in such biological applications in conjunction with graphene sensors. While tunneling diodes can be used in diagnostic applications, TFETs, which are three-terminal devices, further permit controlling the voltage on one cell according to signals received by other cells. Thus, by the use of a biological sensor system that includes graphene nanowire sensors coupled to a TFET, charge can be redistributed among different biological cells, potentially with therapeutic effects.
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公开(公告)号:US20170172475A1
公开(公告)日:2017-06-22
申请号:US15454962
申请日:2017-03-09
Applicant: Sano Intelligence, Inc.
Inventor: Ashwin Pushpala , Dominic Pitera , Matthew Chapman , Michael Gifford
CPC classification number: A61B5/14532 , A61B5/0002 , A61B5/0022 , A61B5/1451 , A61B5/14546 , A61B5/6833 , A61B5/6849 , A61B5/685 , A61B5/688 , A61B5/6885 , A61B5/7285 , A61B5/746 , A61B2562/0214 , A61B2562/028 , A61B2562/046 , A61B2562/164 , G16H40/67
Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.
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公开(公告)号:US20170127984A1
公开(公告)日:2017-05-11
申请号:US15412229
申请日:2017-01-23
Applicant: Sano Intelligence, Inc.
Inventor: Ashwin Pushpala , Matthew Chapman , Alan Szmodis , Abhijit Ghosh
IPC: A61B5/145 , A61B17/34 , A61B5/01 , A61B5/1486 , A61B5/00
CPC classification number: A61B5/14514 , A61B5/0002 , A61B5/0022 , A61B5/01 , A61B5/0537 , A61B5/0538 , A61B5/1451 , A61B5/14532 , A61B5/14546 , A61B5/14865 , A61B5/6833 , A61B5/6849 , A61B5/685 , A61B5/688 , A61B5/6885 , A61B5/7275 , A61B5/7278 , A61B5/7285 , A61B5/746 , A61B17/3468 , A61B2562/0214 , A61B2562/028 , A61B2562/046 , A61B2562/164 , G16H40/67
Abstract: A system and method for monitoring body chemistry of a user, the system comprising: a housing supporting: a microsensor comprising a first and second working electrode, a reference electrode, and a counter electrode, and configured to access interstitial fluid of the user, and an electronics subsystem comprising a signal conditioning module that receives a signal stream, from the microsensor, wherein the electronics subsystem is configured to detect an impedance signal derived from two of the first working electrode, the second working electrode, the reference electrode, and the counter electrode; and a processing subsystem comprising: a first module configured to generate an analysis indicative of an analyte parameter of the user and derived from the signal stream and the impedance signal, and a second module configured to transmit information derived from the analysis to the user, thereby facilitating monitoring of body chemistry of the user.
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