公开(公告)号：US20240299616A1

公开(公告)日：2024-09-12

申请号：US18665926

申请日：2024-05-16

申请人： ABC IP, LLC

发明人： Mladen Thomas Strbac

IPC分类号： A61L24/00 ,  A61L24/04 ,  F41A17/48 ,  F41A19/10 ,  F41A19/15 ,  F41A19/24

CPC分类号： A61L24/0036 ,  A61L24/0015 ,  A61L24/043 ,  F41A17/48 ,  F41A19/10 ,  F41A19/15 ,  F41A19/24 ,  A61L2300/252 ,  A61L2300/418 ,  A61L2400/04 ,  A61L2430/36

摘要： A trigger mechanism that can be used in AR-pattern firearms has a hammer, a trigger member, a disconnector, a locking member, and a “three position” safety selector having safe, standard semi-automatic, and forced reset semi-automatic positions. In the standard semi-automatic position, rearward movement of the bolt carrier causes rearward pivoting of the hammer such that the disconnector hook catches the hammer hook, at which time a user must manually release the trigger member to free the hammer from the disconnector to permit the hammer and trigger member to pivot to the set positions so that the user can pull the trigger member to fire the firearm. In the forced reset semi-automatic position, rearward movement of the bolt carrier causes rearward pivoting of the hammer causing the trigger member to be forced to the set position, the safety selector preventing the disconnector hook from catching the hammer hook, and thereafter when the bolt carrier reaches the substantially in-battery position the user can pull the trigger member to fire the firearm without manually releasing the trigger member. The locking member is pivotable between a first position at which the locking member mechanically blocks the trigger member from moving to the released position and a second position at which the locking member does not mechanically block the trigger member allowing the trigger member to be moved to the released position. The locking member is spring biased toward the first position and moved against the spring bias to the second position by contact from the bolt carrier during forward movement of the bolt carrier as the bolt carrier reaches a substantially in-battery position.

公开(公告)号：US11992482B2

公开(公告)日：2024-05-28

申请号：US15405453

申请日：2017-01-13

申请人： Rilento Pharma, LLC

发明人： Khashayar Kevin Neshat

IPC分类号： A61K31/445 ,  A61K9/06 ,  A61K9/16 ,  A61K9/19 ,  A61K38/48 ,  A61K45/06 ,  A61L24/00 ,  A61P23/02

CPC分类号： A61K31/445 ,  A61K9/06 ,  A61K9/1647 ,  A61K9/19 ,  A61K38/4833 ,  A61K45/06 ,  A61L24/0015 ,  A61L24/0036 ,  A61L24/0094 ,  A61P23/02 ,  C12Y304/21005 ,  A61L2300/402 ,  A61L2300/404 ,  A61L2300/418

摘要： A malleable sustained release formulation is created utilizing a local anesthetic wherein the composition is made sustained release by incorporating it into a bovine or porcine hemostatic agent. The composition is malleable enough to fit into a cavity such as a dental cavity and form the shape of the cavity. In addition to providing sustained release of the anesthetic, the composition also provides quicker reduction in bleeding.

公开(公告)号：US20240082456A1

公开(公告)日：2024-03-14

申请号：US18513436

申请日：2023-11-17

申请人： Medtronic Xomed, Inc.

发明人： Ethan G. Sherman ,  Wei Chen ,  Denise E. Guenther

IPC分类号： A61L24/00 ,  A61F13/20 ,  A61K9/00 ,  A61L2/00 ,  A61L15/22 ,  A61L24/04 ,  A61L24/08 ,  A61L31/04 ,  A61L31/14 ,  A61L31/16 ,  B65B55/16 ,  B65B63/08

CPC分类号： A61L24/0042 ,  A61F13/2005 ,  A61K9/0043 ,  A61L2/0029 ,  A61L15/225 ,  A61L24/0015 ,  A61L24/0036 ,  A61L24/043 ,  A61L24/08 ,  A61L31/042 ,  A61L31/146 ,  A61L31/148 ,  A61L31/16 ,  B65B55/16 ,  B65B63/08 ,  A61L2202/24 ,  A61L2300/232 ,  A61L2300/404 ,  A61L2400/04

摘要： An implantable article comprising a dissolvable sponge derived from the mixture of chitosan, a first polysaccharide and a second polysaccharides. The polysaccharides have different number average molecular weight characteristics to enable the control of the mechanical features of the sponge.

公开(公告)号：US11911524B2

公开(公告)日：2024-02-27

申请号：US17469385

申请日：2021-09-08

申请人： Stryker European Operations Holdings LLC

发明人： Catharina Everdina Hissink ,  Theodorus Adrianus Cornelius Flipsen ,  Johan Zuidema ,  Linda Joan Gibcus

IPC分类号： A61L15/26 ,  C08G18/32 ,  A61L15/42 ,  A61L26/00 ,  C08L75/04 ,  A61L24/00 ,  A61L24/04 ,  C08G18/10 ,  C08G18/42 ,  C08G18/73 ,  A61L15/64 ,  C08G18/08 ,  C08G18/40

CPC分类号： A61L15/26 ,  A61L15/425 ,  A61L15/64 ,  A61L24/0036 ,  A61L24/046 ,  A61L26/0085 ,  C08G18/10 ,  C08G18/14 ,  C08G18/3206 ,  C08G18/4018 ,  C08G18/4277 ,  C08G18/73 ,  C08L75/04 ,  C08G2110/0083 ,  C08G2230/00 ,  A61L24/046 ,  C08L75/04 ,  C08G18/10 ,  C08G18/3206

摘要： The invention relates, generally, to porous absorbent materials which are suitable for packing antrums or other cavities of the human or animal body. More particularly, it relates to hydrophilic biodegradable foams, which may be used e.g. in the form of a plug or tampon, for instance for controlling bleeding, wound closure, prevent tissue adhesion and/or support tissue regeneration. The invention provides an absorbent foam, suitable for packing antrums or other cavities of the human or animal body, comprising a biodegradable synthetic polymer, which polymer preferably comprises —C(O)—O—groups in the backbone of the polymer, for instance polyurethane and/or polyester units combined with polyethers.

公开(公告)号：US20230372577A1

公开(公告)日：2023-11-23

申请号：US18356260

申请日：2023-07-21

申请人： LIFE STAR INTERNATIONAL LIMITED

发明人： Meng-Yi BAI ,  Meng-Chuan Chen ,  Jia-Ying Lin ,  Wei-Yin Chen

IPC分类号： A61L24/10 ,  A61L24/00

CPC分类号： A61L24/106 ,  A61L24/0015 ,  A61L24/0036 ,  A61L2400/04

摘要： Disclosures of the present invention describe a double-layer dressing containing silk fibroin and a method for making the same, wherein the double-layer dressing mainly comprises a silk fibroin layer and a calcium-degradation silk fibroin layer connected to the silk fibroin layer, and it is worth emphasizing that, results of animal experiment have proved that this novel double-layer dressing is an outstanding hemostatic wound dressing; Moreover, additional adhesion, resulted from the solidification of tissue fluid, can be effectively prevented from forming between skin wound and wound dressing under the use of this double-layer dressing.

公开(公告)号：US20190184056A1

公开(公告)日：2019-06-20

申请号：US15844450

申请日：2017-12-15

申请人： MANAR M. JAMAL

发明人： MANAR M. JAMAL

IPC分类号： A61L24/00 ,  A61L24/02 ,  A61L27/38 ,  A61L27/36 ,  A61L27/12 ,  A61L27/10 ,  A61L27/02 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L24/10 ,  A61L27/24 ,  A61C13/15 ,  A61F2/28 ,  A61C8/02

CPC分类号： A61L24/0036 ,  A61C8/0006 ,  A61C19/003 ,  A61F2/2857 ,  A61F2002/2835 ,  A61F2002/3093 ,  A61F2250/0081 ,  A61L24/0005 ,  A61L24/0015 ,  A61L24/0042 ,  A61L24/02 ,  A61L24/102 ,  A61L27/025 ,  A61L27/10 ,  A61L27/12 ,  A61L27/24 ,  A61L27/3608 ,  A61L27/365 ,  A61L27/3821 ,  A61L27/3834 ,  A61L27/3847 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/414 ,  A61L2300/604 ,  A61L2300/64 ,  A61L2430/02 ,  A61L2430/12 ,  A61L2430/34

摘要： A method comprising the steps of applying an adhesive composition to a substrate bone repair region. The adhesive composition comprises a porous, biocompatible, biodegradable, resorbable, non-toxic, and polymerizable composition. The substrate bone repair region comprises a bone structure, implant or device surface, or tooth surface. The adhesive composition is cured to provide a polymerized adhesive composition resulting in repairing or augmenting the substrate bone repair region. The adhesive composition may be mixed with a bone graft material before application. The adhesive composition may be additionally applied to a barrier membrane that is placed over the substrate bone repair region where the adhesive composition or combination of adhesive composition and bone graft material is applied.

公开(公告)号：US09999703B2

公开(公告)日：2018-06-19

申请号：US14980254

申请日：2015-12-28

申请人： FERROSAN MEDICAL DEVICES A/S

发明人： Kristian Larsen

IPC分类号： A61K38/48 ,  A61K9/19 ,  A61K31/047 ,  A61L26/00 ,  A61K31/70 ,  A61K9/16 ,  A61K38/01 ,  A61L24/00 ,  A61L24/10 ,  A61L2/04 ,  A61L2/08 ,  A61L2/10 ,  A61L2/20 ,  B65B1/04 ,  B65D81/32 ,  A61L2/07

CPC分类号： A61L26/0047 ,  A61K9/1658 ,  A61K31/047 ,  A61K31/70 ,  A61K38/014 ,  A61L2/04 ,  A61L2/07 ,  A61L2/081 ,  A61L2/082 ,  A61L2/087 ,  A61L2/10 ,  A61L2/202 ,  A61L2/204 ,  A61L2/206 ,  A61L2/208 ,  A61L24/0015 ,  A61L24/0036 ,  A61L24/104 ,  A61L26/00 ,  A61L26/0038 ,  A61L26/0066 ,  A61L2300/254 ,  A61L2300/418 ,  A61L2300/802 ,  A61L2400/04 ,  A61L2400/06 ,  B65B1/04 ,  B65D81/32

摘要： The present invention relates to a dry composition, which upon addition of an aqueous medium forms a substantially homogenous paste suitable for use in haemostasis procedures. The paste forms spontaneously upon addition of the liquid, hence no mechanical mixing is required for said paste to form. The invention further relates to methods of preparing said dry composition, a paste made from said dry composition and use of said paste for medical and surgical purposes.

公开(公告)号：US09931435B2

公开(公告)日：2018-04-03

申请号：US15137188

申请日：2016-04-25

申请人： Warsaw Orthopedic, Inc.

发明人： Jeffrey L. Scifert ,  William F. McKay

IPC分类号： A61K9/70 ,  A61L27/24 ,  A61K9/00 ,  A61K9/16 ,  A61L27/58 ,  A61L24/00 ,  A61L24/10 ,  A61L27/46 ,  A61F2/02 ,  A61L24/02 ,  A61L27/02 ,  A61L27/54 ,  A61L27/56

CPC分类号： A61L27/24 ,  A61F2/02 ,  A61K9/0019 ,  A61K9/0024 ,  A61K9/1652 ,  A61L24/0015 ,  A61L24/0036 ,  A61L24/0042 ,  A61L24/0084 ,  A61L24/02 ,  A61L24/10 ,  A61L24/102 ,  A61L27/02 ,  A61L27/46 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2300/112 ,  A61L2300/252 ,  A61L2300/412 ,  A61L2300/414 ,  A61L2300/45 ,  A61L2300/604 ,  A61L2400/06 ,  A61L2430/02 ,  A61L2430/38

摘要： Described is a medically useful article comprising a three-dimensional body including one or more implantable substances, wherein the body defines one or more reservoirs for receiving amounts of a biocompatible wetting liquid. In certain embodiments the body is disruptable upon wetting with the biocompatible liquid to form a conformable implantable material such as a putty, paste or more flowable wetted implant material. Also described are methods for manufacturing such medical materials, and methods for using such medical materials to treat patients.

公开(公告)号：US09931429B2

公开(公告)日：2018-04-03

申请号：US14643992

申请日：2015-03-10

申请人： Boston Scientific Scimed, Inc.

发明人： Robert F. Rioux ,  Thomas V. Casey, II ,  Janel Lanphere

IPC分类号： A61K9/14 ,  A61K51/00 ,  A61L24/02 ,  A61K9/16 ,  A61K49/04 ,  A61L24/00 ,  A61B18/18 ,  A61K51/12

CPC分类号： A61L24/02 ,  A61B18/18 ,  A61K9/14 ,  A61K9/1635 ,  A61K9/1652 ,  A61K49/0452 ,  A61K51/1244 ,  A61L24/0015 ,  A61L24/0036 ,  A61L24/0089 ,  A61L2300/102 ,  A61L2300/418 ,  A61L2300/606 ,  A61L2400/04 ,  A61L2430/36

摘要： A particle includes a ferromagnetic material, a radiopaque material, and/or an MRI-visible material.

公开(公告)号：US20170312385A1

公开(公告)日：2017-11-02

申请号：US15497720

申请日：2017-04-26

申请人： Anika Therapeutics, Inc.

发明人： Edward S. AHN ,  Chia-En LIN ,  Colin D. WHITE

IPC分类号： A61L27/20 ,  A61B17/88 ,  A61L27/02 ,  A61B17/34 ,  A61L27/50 ,  A61L27/12 ,  A61B17/00

CPC分类号： A61L27/20 ,  A61B17/3472 ,  A61B17/8816 ,  A61B17/8825 ,  A61B17/8833 ,  A61B2017/00893 ,  A61B2017/8838 ,  A61L24/0031 ,  A61L24/0036 ,  A61L24/0042 ,  A61L24/0084 ,  A61L27/025 ,  A61L27/12 ,  A61L27/46 ,  A61L27/50 ,  A61L27/52 ,  A61L27/56 ,  A61L27/58 ,  A61L2400/06 ,  A61L2430/02 ,  C08L5/08

摘要： The present disclosure relates to methods and compositions for the treatment of degenerate bone in a patient. In some embodiments, the methods and compositions disclosed herein are useful in the treatment, prevention, or in delaying the progression of a bone disease linked to bone degeneration, such as osteoarthritis (“OA”), rheumatoid arthritis, and avascular necrosis.