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    Antimicrobial agent against acid-resistant and heat-resistant bacteria
    2.
    发明授权
    Antimicrobial agent against acid-resistant and heat-resistant bacteria 失效
    耐酸，耐热细菌的抗微生物剂

    公开(公告)号：US06329011B1

    公开(公告)日：2001-12-11

    申请号：US09680403

    申请日：2000-10-05

    申请人： Shigeru Oita

    发明人： Shigeru Oita

    IPC分类号： A61K3800

    CPC分类号： C07K14/415 ,  A23L2/02 ,  A23L2/44 ,  A61K38/168 ,  Y10S435/832 ,  Y10S435/833 ,  Y10S435/834 ,  Y10S435/835 ,  Y10S435/836 ,  Y10S435/837 ,  Y10S435/838 ,  Y10S435/839

    摘要： An antimicrobial agent with a high degree of safety is provided, which is derived from a natural product and can exhibit growth-inhibitory activity against acid-resistant and heat-resistant bacteria such as Alicyclobacillus acidoterrestris, which is resistant against pasteurization and causes spoilage of fruit juice. The antimicrobial agent against acid-resistant and heat-resistant bacteria contains as an effective ingredient alpha-type thionin and/or beta-type thionin. A preservative for fruit juice is also provided, which contains as an effective ingredient the alpha-type thionin and/or beta-type thionin.

    摘要翻译： 提供了具有高度安全性的抗微生物剂，其来自天然产物，并且可以对抗酸碱环境酸杆菌的抗酸耐热细菌表现出抑制生物的活性，其耐巴氏灭菌并引起水果的腐败 果汁。 针对耐酸耐热细菌的抗微生物剂含有α型硫素和/或β型硫素的有效成分。 还提供了果汁防腐剂，其含有α型硫素和/或β型硫素作为有效成分。

    Detection of microbial metabolites with a 3-indoxyl-myo-inositol-1-phosphate compound
    3.
    发明授权
    Detection of microbial metabolites with a 3-indoxyl-myo-inositol-1-phosphate compound 失效
    用3-茚氧基 - 肌醇-1-磷酸酯化合物检测微生物代谢物

    公开(公告)号：US6068988A

    公开(公告)日：2000-05-30

    申请号：US988540

    申请日：1997-12-10

    申请人： Gunter Schabert ,  Urs P. Spitz ,  Roland Humm

    发明人： Gunter Schabert ,  Urs P. Spitz ,  Roland Humm

    IPC分类号： C07F9/572 ,  C07F9/6561 ,  C12Q1/04 ,  C12Q1/34 ,  C12Q1/44 ,  C12Q1/42 ,  C07D209/04 ,  C07H5/04 ,  C12N9/18

    CPC分类号： C12Q1/34 ,  C07F9/5728 ,  C12Q1/44 ,  C12Q2334/52 ,  G01N2333/916 ,  Y10S435/834 ,  Y10S435/883

    摘要： A method of detecting a phosphatidylinositol-specific phospholipase C enzyme by means of a substrate which is cleaved by said enzyme and yields a dye when the chromophoric portion of the substrate is dimerized and oxidized; the invention teaches using in such method, as a novel substrate, a 3-indoxyl-myo-inositol-1-phosphate compound of formula (I) ##STR1## wherein R is selected from the group consisting of hydrogen and C.sub.1-4 alkyl, while R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are radicals selected from the group consisting of hydrogen, halogen, cyano, nitro, carboxy, amino, alkyl-substituted amino and sulphonyl; or of a salt of said formula I compound. The invention provides for a safe and sensitive method of detection of potentially pathogenic bacterial activity of such microbes as Bacillus cereus, B. Thuringiensis, Staphy lococcus aureus and various Listeria strains in potentially infected materials including physiological samples or consumable goods such as foods and beverages.

    摘要翻译： 一种通过底物切割磷脂酰肌醇特异性磷脂酶C酶的方法，当底物的发色部分被二聚化和氧化时，产生染料; 本发明教导以这种方法使用式（I）的3-茚氧基 - 肌醇-1-磷酸化合物作为新的底物，其中R选自氢和C 1-4烷基，而R 1， R2，R3和R4是选自氢，卤素，氰基，硝基，羧基，氨基，烷基取代的氨基和磺酰基的基团。 或所述式I化合物的盐。 本发明提供了一种安全和敏感的方法，用于检测诸如蜡状芽孢杆菌，苏云金芽孢杆菌，金黄色葡萄球菌和各种利斯特氏菌属在包括生理样品或消费品如食物和饮料的潜在感染材料中的潜在致病细菌活性。

    Methods for controlling above-ground plant diseases using antibiotic-producing bacillus sp. ATCC 55608 or 55609
    5.
    发明授权
    Methods for controlling above-ground plant diseases using antibiotic-producing bacillus sp. ATCC 55608 or 55609 失效
    使用抗生素产芽孢杆菌菌种控制地上植物病害的方法 ATCC 55608或55609

    公开(公告)号：US5869042A

    公开(公告)日：1999-02-09

    申请号：US755060

    申请日：1996-11-22

    申请人： Pamela Gail Marrone ,  Sherry D. Heins ,  Desmond R. Jimenez

    发明人： Pamela Gail Marrone ,  Sherry D. Heins ,  Desmond R. Jimenez

    IPC分类号： A01N47/28 ,  A01N63/00 ,  A01N63/02 ,  A01N33/00 ,  C12N1/20 ,  C12P13/00

    CPC分类号： A01N63/02 ,  A01N47/28 ,  A01N63/00 ,  Y10S435/834

    摘要： Above-ground fungal and bacterial infections of plants are treated by applying to the plants an antibiotic-producing Bacillus sp. strain ATCC 55608, 55609, 53522 and/or zwittermicin-A antibiotic therefrom. The above-ground infections treated can be caused by Phytophthora infestans, Botrytis cinerea, Pseudomonas syringae, Alternaria solani, Plasmopara viticola, Uncinula necator, Puccinia recondita f.sp. Tritici, Staganospora nodorum, Monilinia fructicola or Erwinia herticola. The Bacillus sp. and/or antibiotic when applied can be in the form of a whole culture broth, an antibiotic-containing supernatant, a powder, granules, a concentrate, an aqueous suspension or a microencapsulated formulation.

    摘要翻译： 通过向植物施用产生抗生素的芽孢杆菌属植物来处理植物的地上真菌和细菌感染。 菌株ATCC 55608,55609,53522和/或两性霉素A抗生素。 治疗的地上感染可以由致病疫霉，灰葡萄孢，丁香假单胞菌，链格孢（Alternaria solani），葡萄孢霉（Plasmopara viticola），Uncinula necator 小麦，斯氏a um，Monilinia fructicola或Erwinia herticola。 芽孢杆菌 和/或抗生素可以是整个培养液，含抗生素的上清液，粉末，颗粒剂，浓缩物，水性悬浮液或微囊化制剂的形式。

    Biological process of remediating chemical contamination of a pond
    6.
    发明授权
    Biological process of remediating chemical contamination of a pond 失效
    补救池塘化学污染的生物过程

    公开(公告)号：US5736048A

    公开(公告)日：1998-04-07

    申请号：US690455

    申请日：1996-08-02

    申请人： Victor M. Ibeanusi

    发明人： Victor M. Ibeanusi

    IPC分类号： B09C1/10 ,  C02F3/32 ,  C02F3/34

    CPC分类号： B09C1/10 ,  B09C1/105 ,  C02F3/32 ,  C02F3/34 ,  Y10S210/909 ,  Y10S210/912 ,  Y10S210/913 ,  Y10S435/834 ,  Y10S435/946

    摘要： In a process of remediating chemical contamination of a pond contaminated with one or more toxic heavy metals or aromatic compounds, the steps include: preparing a silage of grass clippings, placing the silage on the surface of a pond, and inoculating the pond with an alga and Bacillus cereus in sufficient quantities to cause a mixed algal and bacterial bloom to form on the pond surface and become annealed to the silage, leaving the silage with the annealed bloom on the surface of the pond for a sufficient amount of time to allow the bloom to withdraw at least some of the toxic heavy metal content or to degrade at least some of the aromatic compound content of the pond, and removing the silage with the annealed bloom from the pond.

    摘要翻译： 在修复受一种或多种有毒重金属或芳香族化合物污染的池塘的化学污染的过程中，步骤包括：制备青贮青草，将青贮饲料放置在池塘表面，并用藻类接种池塘 和蜡状芽孢杆菌足够量以在池塘表面上形成混合的藻类和细菌绽放，并与青贮饲料退火，留下青贮饲料与池塘表面上的退火花期一段足够的时间以允许开花 退出至少一些有毒的重金属含量或降解池塘中至少一些芳香族化合物含量，并且从池塘中退火的淀粉去除青贮饲料。

    Process for enriching an �R,S!-1,2-epoxide in one enantiomer by using microbes to convert one enantiomer to the other or to preferentially open the epoxide ring
    8.
    发明授权
    Process for enriching an �R,S!-1,2-epoxide in one enantiomer by using microbes to convert one enantiomer to the other or to preferentially open the epoxide ring 失效
    通过使用微生物将一种对映异构体转化为另一对映异构体或优先开环环氧环来富集一种对映异构体中的[R，S]

    公开(公告)号：US5672504A

    公开(公告)日：1997-09-30

    申请号：US547902

    申请日：1995-10-25

    申请人： Akinobu Matsuyama ,  Yoshinori Kobayashi

    发明人： Akinobu Matsuyama ,  Yoshinori Kobayashi

    IPC分类号： C07D303/08 ,  C12P17/02 ,  C12P41/00

    CPC分类号： C07D303/08 ,  C12P17/02 ,  C12P41/00 ,  Y10S435/823 ,  Y10S435/832 ,  Y10S435/834 ,  Y10S435/839 ,  Y10S435/849 ,  Y10S435/875 ,  Y10S435/877 ,  Y10S435/881 ,  Y10S435/917 ,  Y10S435/918 ,  Y10S435/92

    摘要： A microorganism or a preparation thereof is permitted to act on a mixture of enantiomers of an epoxide such as 3-chlorostyrene oxide and the product optically active epoxide is recovered. The microorganism able to produce an optically active (S)-epoxide from the mixture of enantiomers of the epoxide include, for example, a microorganism strain belonging to the genus Candida, the genus Rhodosporidium, the genus Rhodococcus and the genus Nosardioides. Examples of the microorganism capable of producing an optically active (R)-epoxide from said mixture include a microorganism strain belonging to the genus Trichosporon, the genus Geotrichum, the genus Corynebacterium, the genus Micrococcus and the genus Brevibacterium. The objective optically active epoxide can efficiently be obtained with ease and simplicity from the corresponding mixture of enantiomers of the epoxide.

    摘要翻译： 允许微生物或其制剂作用于环氧化物的对映异构体如3-氯苯乙烯氧化物的混合物，并回收产物光学活性环氧化物。 能够从环氧化物的对映异构体的混合物中产生光学活性的（S） - 环氧化物的微生物包括例如属于假丝酵母属，红球菌属，红球菌属和仙人掌属的微生物菌株。 能够从所述混合物生产光学活性（R） - 环氧化物的微生物的实例包括属于Trichosporon属，Geotrichum属，棒状杆菌属，Micrococcus属和短杆菌属的微生物菌株。 目的光学活性环氧化物可以从环氧化物的相应对映异构体的混合物中容易且简单地获得。

    Method to enhance root nodulation in legumes and inoculum preparation therefor
    10.
    发明授权
    Method to enhance root nodulation in legumes and inoculum preparation therefor 失效
    增加豆科植物根系结瘤的方法及其接种物准备

    公开(公告)号：US4878936A

    公开(公告)日：1989-11-07

    申请号：US77937

    申请日：1987-07-27

    申请人： Jo E. Handelsman ,  Larry J. Halverson

    发明人： Jo E. Handelsman ,  Larry J. Halverson

    IPC分类号： C05F11/08

    CPC分类号： C12R1/085 ,  C05F11/08 ,  Y10S435/834

    摘要： A method for enhancing nodulation in legumes growing in a growing medium. The method includes the step of placing in the growing medium in the immediate vicinity of the roots of the legume the nodulation of which is to be enhanced an effective quantity of an enhancing bacteria selected from the group consisting of ATCC 53522, enhancing mutants of ATCC 53522, a mixture of such mutants, and a mixture of such mutants with ATCC 53522.

    摘要翻译： 用于增强在生长培养基中生长的豆类中的结瘤的方法。 该方法包括将生长培养基放置在豆类根部附近的步骤，其结瘤将增强有效量的选自ATCC 53522的增强细菌，增强ATCC 53522的突变体 ，这种突变体的混合物，以及这种突变体与ATCC 53522的混合物。