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公开(公告)号：US20150297380A1
公开(公告)日：2015-10-22
申请号：US14687843
申请日：2015-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Benjamyn Serna , Michael Huy Ngo , Syed F.A. Hossainy , O. Mikael Trollsas
CPC classification number: A61F2/95 , A61F2210/0076 , A61F2230/0063 , A61F2240/001 , A61F2250/0067 , A61L2420/02 , B05D1/002 , B05D1/38 , B05D3/10 , B05D3/12
Abstract: Embodiments of the present invention encompass methods of forming coatings, particularly coatings for medical devices, and more particularly, for braided or woven medical devices. Embodiments of the present invention encompass the coatings and the coated devices. The coatings may include a polymer and optionally a therapeutic agent.
Abstract translation: 本发明的实施例包括形成涂层的方法，特别是用于医疗装置的涂层，更具体地，涉及编织或编织的医疗装置。 本发明的实施例包括涂层和涂覆装置。 涂层可以包括聚合物和任选的治疗剂。
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公开(公告)号：US09161852B2
公开(公告)日：2015-10-20
申请号：US14223844
申请日：2014-03-24
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： John Stankus , Benjamyn Serna
CPC classification number: A61F2/915 , A61F2/958 , A61F2002/91566 , A61F2002/9522 , A61F2240/001 , Y10T29/49908 , Y10T29/49925 , Y10T29/49936
Abstract: A medical device-includes a scaffold crimped to a catheter having an expansion balloon. The scaffold is crimped to the balloon by a process that includes one or more balloon pressurization steps. The balloon pressurization steps are selected to enhance scaffold retention to the balloon while retaining, at least partially, the original balloon folds as the balloon is pressurized and de-pressurized within a crimper head. By at least partially retaining the original balloon folds, a uniformity of scaffold expansion by the balloon is improved.
Abstract translation: 一种医疗装置 - 包括卷曲到具有膨胀气囊的导管的支架。 支架通过包括一个或多个气囊加压步骤的过程卷曲到气囊。 选择气囊加压步骤以增强对球囊的支架保留，同时至少部分地保持原始气囊折叠，当气囊在压接头内进行加压和减压时。 通过至少部分地保持原始的气球褶皱，改善了球囊的支架膨胀的均匀性。
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公开(公告)号：US20150289875A1
公开(公告)日：2015-10-15
申请号：US14253719
申请日：2014-04-15
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Paul Consigny , Erik Eli , Stephen D. Pacetti , Mikael Trollsas , John Stankus , Julia Fox
CPC classification number: A61B17/11 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/848 , A61F2/856 , A61F2/89 , A61F2/91 , A61F2/954 , A61F2/958 , A61F2/966 , A61F2002/821 , A61F2002/828 , A61F2002/91575 , A61F2002/9583 , A61M1/3655
Abstract: Medical devices and methods for forming an arteriovenous (AV) fistula include a stent having an arterial tubular portion and vein supporting tongue connected by a pre-shaped connector and a venous frustoconical stent having a distal end for maintaining a take-off angle for the venous portion of the AV fistula. Also disclosed is an angled balloon for assisting with the formation of the AV fistula. The medical devices disclosed herein support an AV fistula formation having a desired take off angle of about 30 degrees, or between about 15 and 45 degrees.
Abstract translation: 用于形成动静脉（AV）瘘的医疗装置和方法包括具有动脉管状部分和通过预形连接器连接的静脉支撑舌片的支架和具有用于维持静脉的起飞角度的远端的静脉截头圆锥形支架 部分AV瘘。 还公开了一种用于辅助AV瘘形成的成角度的球囊。 本文公开的医疗装置支持AV瘘形成，其具有约30度或约15度至45度的期望的脱离角度。
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公开(公告)号：USRE45744E1
公开(公告)日：2015-10-13
申请号：US14074543
申请日：2013-11-07
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： David C. Gale , Bin Huang , Anthony Abbate , Stephen D. Pacetti
IPC: A24B5/00 , A61F2/958 , A61L31/10 , A61L31/14 , B29B13/02 , B29C65/00 , B29C65/76 , B29C65/56 , B29C35/08 , B29C71/02 , B29K1/00 , B29K23/00 , B29K27/06 , B29K27/00 , B29K29/00 , B29K31/00 , B29K33/00 , B29K33/20 , B29K55/02 , B29K63/00 , B29K75/00 , B29K77/00 , B29K83/00 , B29L31/00 , A61F2/95
CPC classification number: A61F2/958 , A61F2002/9522 , A61L31/06 , A61L31/10 , A61L31/14 , B29B13/024 , B29C65/56 , B29C65/76 , B29C66/71 , B29C66/73117 , B29C66/9121 , B29C66/91431 , B29C66/91641 , B29C66/919 , B29C66/91921 , B29C66/91941 , B29C66/91945 , B29C2035/0822 , B29C2071/022 , B29K2001/00 , B29K2001/12 , B29K2023/00 , B29K2023/083 , B29K2023/086 , B29K2027/06 , B29K2027/08 , B29K2027/16 , B29K2029/00 , B29K2031/00 , B29K2033/08 , B29K2033/20 , B29K2055/02 , B29K2063/00 , B29K2075/00 , B29K2077/00 , B29K2083/00 , B29L2031/7542 , Y10T29/49865 , Y10T428/24942 , Y10T428/3154 , Y10T428/31544 , Y10T428/31855 , B29K2079/08 , B29K2071/00 , B29K2069/00 , B29K2067/04 , B29K2067/00 , B29K2059/00 , B29K2033/12 , B29K2025/08 , B29K2023/18 , B29K2023/08 , C08L67/04
Abstract: This disclosure describes a method for crimping a polymeric stent onto a catheter for percutaneous transluminal coronary angioplasty or other intraluminal interventions. The method comprises crimping the stent onto a catheter when the polymer is at a target temperature other than ambient temperature. The polymer can optionally comprise drug(s).
Abstract translation: 本公开描述了一种用于将聚合物支架卷曲到用于经皮冠状动脉腔内冠状动脉成形术或其他管腔内干预的导管上的方法。 该方法包括当聚合物处于不同于环境温度的目标温度时将支架卷曲到导管上。 聚合物可任选地包含药物。
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公开(公告)号：US20150267000A1
公开(公告)日：2015-09-24
申请号：US14732568
申请日：2015-06-05
Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
Inventor： Jessica Renee DesNoyer , Stephen Dirk Pacetti , Vidya Nayak , Lothar Kleiner
CPC classification number: C08G69/48 , A61L27/34 , A61L31/041 , A61L31/06 , A61L31/10 , A61L31/16 , A61L2300/416 , C08G69/44 , Y10T428/31551 , Y10T428/31725 , C08L77/12
Abstract: This invention relates to poly(ester amide)s (PEAs) comprising inactivated terminal amino and carboxyl groups, methods of synthesizing the inactivated PEAs and uses for them in the treatment of vascular diseases.
Abstract translation: 本发明涉及包含灭活的末端氨基和羧基的聚（酯酰胺）（PEA），合成灭活的PEAs的方法及其用于治疗血管疾病的用途。
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Patent Agency Ranking
公开(公告)号：US20150265438A1
公开(公告)日：2015-09-24
申请号：US14662171
申请日：2015-03-18
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Syed Hossainy , Jason Van Sciver , Chad Abunassar
CPC classification number: A61F2/89 , A61F2/844 , A61F2/915 , A61F2/958 , A61F2002/072 , A61F2002/91566 , A61F2210/0004 , A61F2230/0067 , A61F2230/0078 , A61F2250/0018 , A61F2250/0023 , A61F2250/0036 , A61F2250/0039 , A61F2250/0067 , A61L31/041 , C08L67/04
Abstract: A stent or scaffold has a tapered end or ends. The scaffold is made using an additive manufacturing technique such as stereolithography (SLA). The scaffold may take the shape of a frustum, or a scaffold having one or both of its ends flared. The scaffold has varying mechanical properties over its length, such as a varying ring stiffness, porosity or elasticity modulus. In one embodiment the strut and link widths change linearly from the distal to proximal ends.
Abstract translation: 支架或支架具有锥形的端部或端部。 支架采用立体光刻（SLA）等添加剂制造技术制成。 支架可以采用平截头体的形状，或者其支架的一端或两端扩张的支架。 支架在其长度上具有不同的机械性能，例如变化的环刚度，孔隙率或弹性模量。 在一个实施例中，支柱和连杆宽度从远端线向近端改变。
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177.发明授权公开(公告)号：US09138337B2
公开(公告)日：2015-09-22
申请号：US14192705
申请日：2014-02-27
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Dugan
IPC: A61F2/02 , A61F2/91 , A61K9/00 , A61K9/16 , A61L27/54 , A61L27/58 , A61K31/4745 , A61K31/573 , A61K31/436
CPC classification number: A61L31/16 , A61F2/91 , A61F2250/0067 , A61F2250/0068 , A61K9/0024 , A61K9/1647 , A61K31/436 , A61K31/4745 , A61K31/573 , A61L27/54 , A61L27/58 , A61L31/10 , A61L31/148 , A61L2300/204 , A61L2300/216 , A61L2300/41 , A61L2300/416 , A61L2300/604 , A61K2300/00
Abstract: Drug-delivery systems such as drug-delivery stents having an anti-proliferative agent such as everolimus and an anti-flammatory agent such as clobetasol are provided. Also disclosed are methods of treating a vascular impairment such as restenosis or vulnerable plaque.
Abstract translation: 提供了药物递送系统，例如具有抗增殖剂如依维莫司的药物递送支架和抗炎剂如氯倍他索。 还公开了治疗血管损伤如再狭窄或易损斑块的方法。
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公开(公告)号：US09119741B2
公开(公告)日：2015-09-01
申请号：US13848683
申请日：2013-03-21
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Annie P Liu , Jason Phillips , Mark C Johnson , Sean McNiven
CPC classification number: A61M25/10 , A61F2/0095 , A61F2/958 , A61F2/962 , A61F2002/9522 , A61M25/1036 , A61M2025/1081 , Y10T29/49865 , Y10T29/49913
Abstract: A medical device includes a polymer scaffold crimped to a catheter having an expansion balloon. A sheath pair is placed over the crimped scaffold after crimping to reduce recoil of the crimped polymer scaffold and maintain scaffold-balloon engagement relied on to hold the scaffold to the balloon when the scaffold is being delivered to a target in a body. The sheath pair is removed by a health professional before placing the scaffold within the body.
Abstract translation: 医疗装置包括压接到具有膨胀气囊的导管的聚合物构架。 在卷曲之后，将鞘对放置在卷曲框架上方，以减少卷曲聚合物支架的反冲，并且当支架被递送到身体中的目标时，保持脚手架气球接合以将支架保持在气囊上。 在将支架放入体内之前，保健专业人员将护套对移除。
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179.发明申请DRUG DELIVERY SCAFFOLD OR STENT WITH A NOVOLIMUS AND LACTIDE BASED COATING SUCH THAT NOVOLIMUS HAS A MINIMUM AMOUNT OF BONDING TO THE COATING 有权药物递送SCAFFOL或STENT与NOVOLIMUS和LACTIDE这样的涂层，如果NOVOLIMUS具有最少量的粘合到涂层公开(公告)号：US20150217029A1
公开(公告)日：2015-08-06
申请号：US14298616
申请日：2014-06-06
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Ni Ding , Stephen Pacetti , Marika Kamberi , Cameron Kerrigan
CPC classification number: A61L31/16 , A61K31/436 , A61K47/593 , A61K47/6957 , A61L31/10 , A61L31/148 , A61L2300/416 , A61L2420/02 , C08L67/04
Abstract: Disclosed herein are drug delivery medical devices. A polymer coating for a medical device is provided which comprises a minimum amount of a drug bonded to the polymer in the coating.
Abstract translation: 本文公开了药物递送医疗装置。 提供了一种用于医疗装置的聚合物涂层，其包括与涂层中的聚合物结合的最少量的药物。
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公开(公告)号：US20150217028A1
公开(公告)日：2015-08-06
申请号：US14613304
申请日：2015-02-03
Applicant: Abbott Cardiovascular Systems Inc.
Inventor： Stephen Pacetti , Fuh-Wei Tang , Xiao Ma , Ni Ding , Derek Mortisen
CPC classification number: A61L31/06 , A61F2/82 , A61F2/91 , A61F2210/0004 , A61F2240/001 , A61F2250/0067 , A61K47/593 , A61L2/087 , A61L31/10 , A61L31/148 , A61L2300/606 , B29B13/08 , B29C71/04 , B29C2035/0827 , B29C2035/085 , B29C2035/0877 , C08G63/08 , C08G63/912
Abstract: It is provided herein modified polylactide (PLA) polymers comprising biocompatibile functional group(s) on the polymers and methods of making and using the modified PLA polymers.
Abstract translation: 提供了在聚合物上包含生物相容性官能团的改性聚丙交酯（PLA）聚合物以及制备和使用改性PLA聚合物的方法。
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