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53 条记录 (耗时 0.041 秒)

    Method and apparatus for displaying information
    27.
    发明授权
    Method and apparatus for displaying information 失效
    用于显示信息的方法和装置

    公开(公告)号：US06888543B2

    公开(公告)日：2005-05-03

    申请号：US10435660

    申请日：2003-05-09

    申请人： Donald E. Ingber ,  Sui Huang ,  Gabriel Eichler

    发明人： Donald E. Ingber ,  Sui Huang ,  Gabriel Eichler

    IPC分类号： G06T11/60 ,  G06T17/00

    CPC分类号： G06T11/60

    摘要： A method for displaying large amounts of information. The method includes the steps of forming a spatial layout of tiles each corresponding to a representative reference element; mapping observed elements onto the spatial layout of tiles of representative reference elements; assigning a respective value to each respective tile of the spatial layout of the representative elements; and displaying an image of the spatial layout of tiles of representative elements. Each tile includes atomic attributes of representative elements. The invention also relates to an apparatus for displaying large amounts of information. The apparatus includes a tiler forming a spatial layout of tiles, each corresponding to a representative reference element; a comparator mapping observed elements onto said spatial layout of tiles of representative reference elements; an assigner assigning a respective value to each respective tile of said spatial layout of representative reference elements; and a display displaying an image of the spatial layout of tiles of representative reference elements.

    摘要翻译： 一种显示大量信息的方法。 该方法包括以下步骤：形成各自对应于代表参考元素的瓦片的空间布局; 将观察到的元素映射到代表参考元素的瓦片的空间布局上; 将相应的值分配给代表元素的空间布局的每个相应瓦片; 并显示代表性元素的瓦片的空间布局的图像。 每个瓦片包括代表性元素的原子属性。 本发明还涉及一种显示大量信息的装置。 该装置包括形成瓦片的空间布局的分片器，每个对应于代表参考元件; 将观察到的元素映射到代表性参考元素的瓦片的所述空间布局上的比较器; 分配器，将代表参考元素的所述空间布局的相应值分配给相应的值; 以及显示代表参考元素的瓦片的空间布局的图像的显示器。

    Device and method for combined microfluidic-micromagnetic separation of material in continuous flow
    29.
    发明授权
    Device and method for combined microfluidic-micromagnetic separation of material in continuous flow 有权
    用于连续流动中材料的组合微流控 - 微磁分离的装置和方法

    公开(公告)号：US09220831B2

    公开(公告)日：2015-12-29

    申请号：US12088975

    申请日：2006-10-06

    申请人： Donald E. Ingber ,  Shannon Xia ,  Tom P. Hunt ,  Robert M. Westervelt

    发明人： Donald E. Ingber ,  Shannon Xia ,  Tom P. Hunt ,  Robert M. Westervelt

    IPC分类号： G01N15/14 ,  A61M1/36 ,  B03C1/28

    CPC分类号： A61M1/3618 ,  A61M1/36 ,  A61M2205/0244 ,  A61M2206/11 ,  B01L3/502761 ,  B01L2200/0636 ,  B01L2200/0668 ,  B01L2300/06 ,  B01L2300/0864 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  G01N15/1459 ,  G01N15/1463 ,  G01N15/1484 ,  G01N2015/149 ,  Y10T436/25375

    摘要： A miniaturized, integrated, microfluidic device pulls materials bound to magnetic particles from one laminar flow path to another by applying a local magnetic field gradient. The device removes microbial and mammalian cells from flowing biological fluids without any wash steps. A microfabricated high-gradient magnetic field concentrator (HGMC) is integrated at one side of a microfluidic channel. When magnetic particles are introduced into one flow path, they remain limited to that flow path. When the HGMC is magnetized, the magnetic beads are pulled from the initial flow path into the collection stream, thereby cleansing the fluid. The microdevice allows large numbers of beads and materials to be sorted simultaneously, has no capacity limit, does not lose separation efficiency as particles are removed, and is useful for cell separations from blood and other biological fluids. This on-chip separator allows cell separations to be performed in the field outside of hospitals and laboratories.

    摘要翻译： 小型化，集成的微流体装置通过施加局部磁场梯度将与磁性颗粒结合的材料从一个层流路径拉到另一层。 该装置在没有任何洗涤步骤的情况下除去微生物和哺乳动物细胞流动的生物流体。 微加工的高梯度磁场集中器（HGMC）集成在微流体通道的一侧。 当磁性颗粒被引入一个流动路径时，它们仍然限于该流动路径。 当HGMC被磁化时，将磁珠从初始流动路径拉入收集流，从而清洁流体。 微型装置允许大量的珠粒和材料同时分选，没有容量限制，在颗粒被去除时不会失去分离效率，并且可用于从血液和其它生物流体中分离细胞。 这种片上分离器允许在医院和实验室外的实地进行细胞分离。

    METHODS AND USES FOR EX VIVO TISSUE CULTURE SYSTEMS
    30.
    发明申请
    METHODS AND USES FOR EX VIVO TISSUE CULTURE SYSTEMS 有权
    方法和用于EX VIVO组织文化系统

    公开(公告)号：US20140186414A1

    公开(公告)日：2014-07-03

    申请号：US14122273

    申请日：2012-05-31

    申请人： Donald E. Ingber ,  Yusuke Torisawa ,  Geraldine Hamilton ,  Akiko Mammoto ,  Tadanori Mammoto ,  Catherine Spina

    发明人： Donald E. Ingber ,  Yusuke Torisawa ,  Geraldine Hamilton ,  Akiko Mammoto ,  Tadanori Mammoto ,  Catherine Spina

    IPC分类号： C12N5/077

    CPC分类号： C12N5/0669 ,  A01N1/0247 ,  A61K35/28 ,  G01N27/44791

    摘要： The technology described herein is directed to methods and devices that can be used to induce functional organ structures to form within an implantation device by implanting it in vivo within the body of a living animal, and allowing cells and tissues to impregnate the implantation device and establish normal microenvironmental architecture and tissue-tissue interfaces. Then the contained cells and tissues can be surgically removed intact and either transplanted into another animal or maintained ex vivo by perfusing it through one or more of the fluid channels with medium and/or gases necessary for cell survival.

    摘要翻译： 本文描述的技术涉及可用于通过将其体内植入活体动物体内诱导功能性器官结构形成的方法和装置，并允许细胞和组织浸渍植入装置并建立 正常的微环境结构和组织 - 组织界面。 然后，所包含的细胞和组织可以通过外科手术移除，并移植到另一只动物中，或者通过使其通过一个或多个流体通道与细胞存活所需的培养基和/或气体灌注而保持离体。