Method of forming planar lipid double membrane for membrane protein analysis and apparatus therefor
    31.
    发明申请
    Method of forming planar lipid double membrane for membrane protein analysis and apparatus therefor 有权
    形成用于膜蛋白分析的平面脂质双膜的方法及其装置

    公开(公告)号:US20070161101A1

    公开(公告)日:2007-07-12

    申请号:US10586331

    申请日:2005-01-19

    申请人: Shoji Takeuchi

    发明人: Shoji Takeuchi

    IPC分类号: C12M1/34 G01N1/28

    摘要: To provide a method of forming a planar lipid-bilayer membrane for membrane protein analysis, by which downsizing, simplifying, and multichanneling of a device therefor are achieved. A planar lipid-bilayer membrane 24 is formed by filling a microchannel 12 with a buffer solution 18, the microchannel 12 disposed under a horizontal partition wall 13 having an aperture 14; applying a small amount of a lipid solution 20 as a droplet on the aperture 14 filled with the buffer solution 18 to thereby form a thin layer 21 of the lipid solution in a chamber, the chamber 17 being formed at a position corresponding to the aperture 14 and provided with a liquid trap 15 inside the chamber; and applying a buffer solution 23 as a droplet to the chamber 17 from the upper side of the chamber.

    摘要翻译: 提供一种形成用于膜蛋白质分析的平面脂质 - 双层膜的方法,通过该方法可实现其装置的小型化,简化和多元化。 通过用缓冲溶液18填充微通道12形成平面脂双层膜24,微通道12设置在具有孔14的水平分隔壁13的下方; 在填充有缓冲溶液18的孔14上施加少量作为液滴的脂质溶液20,从而在腔室中形成脂质溶液的薄层21,室17形成在对应于孔14的位置 并在室内设置有液体捕集器15; 并且从室的上侧将作为液滴的缓冲溶液23施加到室17。

    Method of forming bilayer membrane by contact between amphipathic monolayers and apparatus therefor
    32.
    发明授权
    Method of forming bilayer membrane by contact between amphipathic monolayers and apparatus therefor 有权
    通过两亲性单层之间的接触形成双层膜的方法及其设备

    公开(公告)号:US08506905B2

    公开(公告)日:2013-08-13

    申请号:US11997058

    申请日:2006-07-26

    摘要: The present invention provides simple and an accurate apparatuses for forming bilayer membranes by the contact of amphipathic monolayers. In one apparatus, amphipathic monolayers are brought into contact and fused by controlling the pressure of liquids introduced from microchannels forming an intersection containing a chamber. In another apparatus, the chamber includes a number of compartments and at least one construction portion. In this apparatus, a droplet is formed within each compartment and contact of amphipatic monolayers is accomplished by adjusting the size of the droplets.

    摘要翻译: 本发明提供了通过两亲性单层接触形成双层膜的简单且准确的装置。 在一个装置中,通过控制从形成包含室的交点的微通道引入的液体的压力,使两亲性单层接触并熔融。 在另一装置中,腔室包括多个隔间和至少一个结构部分。 在该装置中,在每个室内形成液滴,并通过调节液滴的尺寸来实现两相单层的接触。

    Method of producing ice-candy
    33.
    发明授权
    Method of producing ice-candy 有权
    生产冰糖的方法

    公开(公告)号:US08367135B2

    公开(公告)日:2013-02-05

    申请号:US13048192

    申请日:2011-03-15

    申请人: Shoji Takeuchi

    发明人: Shoji Takeuchi

    IPC分类号: A23G9/00

    摘要: An ice-candy forming container is provided which produces ice-candies having a complicated shape copying the face of a cartoon character or the like with higher quality and without a loss in shape. A forming container includes a first mold having a pattern portion formed in one face thereof, and a second mold configured to slide over and along the one face of the first mold, in a close contact relation, in directions designated by arrows A1-A2, so as to contain the first mold therein. In such a containing position, the second mold contacts externally and closely substantially an entire surface of the outer periphery of the pattern portion.

    摘要翻译: 提供了一种冰糖成型容器,其产生具有复杂形状的冰糖,以更高质量复制卡通人物等的面部,并且没有形状损失。 成形容器包括:第一模具,其具有形成在其一个面上的图案部分;以及第二模具,其被构造成沿着箭头A1-A2所示的方向以紧密接触的方式在第一模具的一个面上滑动, 以便在其中容纳第一模具。 在这种容纳位置中,第二模具在图案部分的外周的外表面附近大致接近。

    Microchip for forming emulsion
    34.
    发明授权
    Microchip for forming emulsion 有权
    微芯片用于形成乳液

    公开(公告)号:US08231265B2

    公开(公告)日:2012-07-31

    申请号:US12507369

    申请日:2009-07-22

    IPC分类号: B01F5/06

    摘要: A microchip for forming an emulsion has a first glass substrate, a second glass substrate and a silicon substrate. The silicon substrate has formed therein a first fluid flow path through which a first fluid flows and a second fluid flow path through which a second fluid that is not mixed with the first fluid flows. The first fluid flow path has a plurality of branched flow paths that join at a joint portion. The second fluid flow path communicates with the joint portion. The silicon substrate has formed therein an emulsion formation flow path that faces an edge portion of the second fluid flow path at the joint portion. An emulsion composed of the first fluid and the second fluid that is surrounded by the first fluid is formed in the emulsion formation flow path.

    摘要翻译: 用于形成乳液的微芯片具有第一玻璃基板,第二玻璃基板和硅基板。 硅衬底在其中形成有第一流体流过的第一流体流动路径和不与第一流体混合的第二流体流过的第二流体流动路径。 第一流体流动路径具有连接在接合部分处的多个分支流路。 第二流体流路与接合部连通。 硅衬底中形成有乳液形成流动路径,其在接合部分处面向第二流体流路的边缘部分。 在乳液形成流动路径中形成由第一流体和第一流体包围的由第一流体包围的乳液。

    METHOD OF PREPARING ARTIFICIAL LIPID MEMBRANES OVER MICROAPERTURES OF SUBSTRATE AND SUBSTRATE FOR HOLDING ARTIFICIAL LIPID MEMBRANES
    35.
    发明申请
    METHOD OF PREPARING ARTIFICIAL LIPID MEMBRANES OVER MICROAPERTURES OF SUBSTRATE AND SUBSTRATE FOR HOLDING ARTIFICIAL LIPID MEMBRANES 审中-公开
    用于保存人造脂膜的底物和底物的微孔中制备人造脂膜的方法

    公开(公告)号:US20100307918A1

    公开(公告)日:2010-12-09

    申请号:US12745317

    申请日:2008-10-28

    IPC分类号: C25D1/12 C25D17/06

    CPC分类号: G01N33/48728 A61K9/1277

    摘要: There is provided a method of preparing organic-solvent-free artificial lipid membranes formed over microapertures of a substrate and a substrate for holding the artificial lipid membranes. The method of preparing artificial lipid membranes over microapertures of a substrate includes forming a lipid pattern 5 on the perimeter of microapertures 4 formed in a substrate 1, swelling the lipid pattern 5 by an electroformation method, fusing the swelled lipid pattern, and further swelling the fused lipid pattern for each microaperture to prepare dome-shaped organic-solvent-free lipid membranes 7.

    摘要翻译: 提供了一种制备在基材和用于保持人造脂膜的底物的微孔下形成的不含有机溶剂的人造脂膜的方法。 在底物的微孔上制备人造脂质膜的方法包括在形成于底物1中的微孔4的周边上形成脂质图案5,通过电化学方法使脂质图案5膨胀,使溶胀的脂质图案融化,并进一步溶胀 每个微孔的融合脂质图案制备圆顶状有机溶剂脂质膜7。

    Wiring board, production process thereof and connection method using same
    37.
    发明申请
    Wiring board, production process thereof and connection method using same 审中-公开
    接线板及其生产工艺及其连接方法

    公开(公告)号:US20070246158A1

    公开(公告)日:2007-10-25

    申请号:US11408373

    申请日:2006-04-21

    IPC分类号: B32B3/00

    摘要: The present invention provides a wiring board capable of realizing electrical connectivity even with connection leads having a fine pitch of 100 μm or less. The present invention relates to a wiring board with adhesive film comprising: a wiring board, in which the surface of a connection terminal portion on the end of a connection lead on the wiring board has a non-flat shape formed by a plating method; and, an adhesive film that covers the surface of the connection terminal portion and contains either a thermoplastic resin or a thermoplastic, thermosetting resin.

    摘要翻译: 本发明提供一种能够实现电连接性的布线板,即使是具有100μm以下的细间距的连接引线。 本发明涉及一种具有粘合膜的布线板,包括:布线板,其中布线板上的连接引线端部上的连接端子部分的表面具有通过镀覆方法形成的非平坦形状; 以及覆盖连接端子部的表面并且包含热塑性树脂或热塑性热固性树脂的粘合膜。

    Systems and methods of forming particles
    38.
    发明申请
    Systems and methods of forming particles 审中-公开
    形成颗粒的系统和方法

    公开(公告)号:US20070054119A1

    公开(公告)日:2007-03-08

    申请号:US11368263

    申请日:2006-03-03

    IPC分类号: B32B1/00

    摘要: The present invention generally relates to systems and methods of forming particles and, in certain aspects, to systems and methods of forming particles that are substantially monodisperse. Microfluidic systems and techniques for forming such particles are provided, for instance, particles may be formed using gellation, solidification, and/or chemical reactions such as cross-linking, polymerization, and/or interfacial polymerization reactions. In one aspect, the present invention is directed to a plurality of particles having an average dimension of less than about 500 micrometers and a distribution of dimensions such that no more than about 5% of the particles have a dimension greater than about 10% of the average dimension, which can be made via microfluidic systems. In one set of embodiments, at least some of the particles may comprise a metal, and in certain embodiments, at least some of the particles may comprise a magnetizable material. In another set of embodiments, at least some of the particles may be porous. In some embodiments, the invention includes non-spherical particles. Non-spherical particles may be formed, for example, by urging a fluidic droplet into a channel having a smallest dimension that is smaller than the diameter of a perfect mathematical sphere having a volume of the droplet, and solidifying the droplet, and/or by exposing at least a portion of a plurality of particles to an agent able to remove at least a portion of the particles.

    摘要翻译: 本发明一般涉及形成颗粒的系统和方法,并且在某些方面涉及形成基本上单分散的颗粒的体系和方法。 提供了用于形成这种颗粒的微流体系统和技术,例如,可以使用凝胶化,固化和/或化学反应如交联,聚合和/或界面聚合反应形成颗粒。 在一个方面,本发明涉及平均尺寸小于约500微米的多个颗粒和尺寸分布,使得不超过约5%的颗粒具有大于所述颗粒的约10%的尺寸 平均尺寸,可以通过微流体系统进行。 在一组实施方案中,至少一些颗粒可以包含金属,并且在某些实施方案中,至少一些颗粒可以包含可磁化材料。 在另一组实施方案中,至少一些颗粒可以是多孔的。 在一些实施方案中,本发明包括非球形颗粒。 非球形颗粒可以例如通过将流体液滴推入具有小于具有液滴体积的完美数学球体的直径的最小尺寸的通道,和/或通过 将多个颗粒的至少一部分暴露于能除去至少一部分颗粒的试剂。

    Cabinet with door seal
    39.
    发明授权
    Cabinet with door seal 失效
    柜门与门密封

    公开(公告)号:US5191736A

    公开(公告)日:1993-03-09

    申请号:US729874

    申请日:1991-07-11

    摘要: A structure for locking a display case door including a door handle, a pair of support members supporting the end portions of the handle, a lower support member of which has a through hole, and a locking piece extendably and retractably below the lower support member and having a through hole capable of facing the though hole of the lower support member so that an arm of a lock can be inserted through the both through holes. Since the locking piece can be positioned below and within the lower support member, it does not become any obstruction to the customers. A structure for treating dew drops dropped from a door of a display case including a tray for catching the dropped dew drops, a dew drops scattering inhibitor plate on the front portion of the tray, and a guide path on the rear portion of the tray and sloped down toward a machine room. The dropped dew drops are prevented from being scattered by the inhibitor plate and the collected water quickly and efficiently guided into the machine room by the sloped guide path. A structure for easily attaching without screws a packing support plate to a display case frame at a door position wherein the display case frame has grooves at least on its both inner side surfaces and the packing support plate has flange portions to be inserted into the grooves.

    Aluminum alloy sheet excellent in high-temperature sagging resistance
and sacrificial anode property and having high room-temperature strength
    40.
    发明授权
    Aluminum alloy sheet excellent in high-temperature sagging resistance and sacrificial anode property and having high room-temperature strength 失效
    具有优异的耐高温下垂性和牺牲阳极性且具有高室温强度的铝合金板

    公开(公告)号:US4828936A

    公开(公告)日:1989-05-09

    申请号:US59958

    申请日:1987-06-09

    IPC分类号: B23K35/02 B32B15/01 C22C21/10

    摘要: An aluminum alloy sheet as a fin material for tubes of a heat exchanger, excellent in high-temperature sagging resistance and sacrificial anode property and having a high room-temperature strength, which consists essentially of:Manganese: from 0.95 to 1.50 wt. %,silicon: from 0.5 to 1.2 wt. %,zinc: from 0.1 to 2.0 wt. %,at least one element selected from the group consisting of:copper: from 0.05 to 0.60 wt. %, andmagnesium: from 0.05 to 0.60 wt. %, where, the total amount of said copper and said magnesium being up to 1.0 wt. %, andthe balance being aluminum and incidental impurities.the above-mentioned aluminum alloy sheet may further additionally contain at least one element selected from the group consisting of:chromium: from 0.03 to 0.30 wt. %, andzirconium: from 0.03 to 0.15 wt. % where, the total amount of said chromium and said zirconium being up to 0.4 wt. %.

    摘要翻译: 一种铝合金板作为热交换器管的翅片材料,具有优异的高温下垂阻力和牺牲阳极性能,并且具有高的室温强度,其基本上由以下组成:锰:0.95至1.50wt。 %,硅:0.5〜1.2wt。 %,锌:0.1〜2.0wt。 %,选自:铜:0.05〜0.60重量%的至少一种元素。 %,镁:0.05〜0.60重量%。 %,其中所述铜和所述镁的总量高达1.0wt。 %,余量为铝和杂质。 上述铝合金板还可以另外含有选自以下的至少一种元素:铬:0.03〜0.30重量% %,锆:0.03〜0.15wt。 %,其中所述铬和所述锆的总量高达0.4wt。 %。