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362 条记录 (耗时 0.046 秒)

    METHODS AND SYSTEMS FOR TREATING NERVE STRUCTURES
    32.
    发明申请
    METHODS AND SYSTEMS FOR TREATING NERVE STRUCTURES 审中-公开
    用于治疗神经结构的方法和系统

    公开(公告)号：US20150223877A1

    公开(公告)日：2015-08-13

    申请号：US14620234

    申请日：2015-02-12

    申请人： Perseus-BioMed Inc.

    发明人： Boaz Behar ,  Yoni Hertzberg ,  Avishai Henley

    IPC分类号： A61B18/14 ,  A61N7/00 ,  A61M5/00 ,  A61N5/10 ,  A61M37/00 ,  A61B18/18 ,  A61B18/04

    CPC分类号： A61B18/1492 ,  A61B18/04 ,  A61B18/1815 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00779 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/0088 ,  A61B2018/00982 ,  A61B2018/1861 ,  A61M5/00 ,  A61M37/0092 ,  A61N5/10 ,  A61N7/00 ,  A61N7/022 ,  A61N2007/003 ,  A61N2007/0069

    摘要： There is provided a method of treating a patient comprising: screening a patient suffering from signs and/or symptoms of at least one medical condition secondary to increased sympathetic tone; selecting the patient for treatment by ablation of at least one neural structure containing sympathetic nerves to reduce the sympathetic tone, the neural structure comprises one or more of: celiac ganglion, superior mesenteric ganglion, inferior mesenteric ganglion, aorticorenal ganglion; selecting a target of at least one measurable parameter affected by the sympathetic tone; ablating at least a portion of the neural structure to deactivate the portion of the neural structure; monitoring changes in the at least one measurable parameter; comparing the at least one measurable parameter to the selected target; and performing another ablation of the same neural structure, and/or another neural structure, based on the comparison.

    摘要翻译： 提供了一种治疗患者的方法，包括：筛选患有继发于增加的交感神经张力的至少一种医学病症的体征和/或症状的患者; 通过消融至少一种包含交感神经的神经结构以减少交感神经张力来选择患者进行治疗，所述神经结构包括以下中的一种或多种：腹腔神经节，肠系膜上神经节，肠系膜下神经节，主动脉肾神经节; 选择受到交感音影响的至少一个可测量参数的目标; 消融所述神经结构的至少一部分以使所述神经结构的所述部分失活; 监测至少一个可测量参数的变化; 将所述至少一个可测量参数与所选择的目标进行比较; 并且基于该比较执行相同神经结构和/或另一神经结构的另一消融。

    APPARATUS AND METHODS FOR TREATING RHINITIS
    33.
    发明申请
    APPARATUS AND METHODS FOR TREATING RHINITIS 有权
    装置和方法治疗RHINITIS

    公开(公告)号：US20150164571A1

    公开(公告)日：2015-06-18

    申请号：US14503060

    申请日：2014-09-30

    申请人： Nidus Medical, LLC

    发明人： Vahid SAADAT

    IPC分类号： A61B18/02 ,  A61B1/04 ,  A61B1/233

    CPC分类号： A61B18/02 ,  A61B1/04 ,  A61B1/233 ,  A61B17/24 ,  A61B18/1485 ,  A61B2018/0022 ,  A61B2018/00327 ,  A61B2018/00434 ,  A61B2018/00577 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/00982 ,  A61B2018/0212 ,  A61B2018/0268 ,  A61B2018/143 ,  A61B2018/1475 ,  A61B2090/378 ,  A61B2218/002 ,  A61N7/02 ,  A61N7/022 ,  A61N2007/003

    摘要： Apparatus and methods for treating conditions such as rhinitis are disclosed herein where a distal end of a probe shaft is introduced through the nasal cavity where the distal end has an end effector with a first configuration having a low-profile which is shaped to manipulate tissue within the nasal cavity. The distal end may be positioned into proximity of a tissue region having a post nasal nerve associated with a middle or inferior nasal turbinate. Once suitably positioned, the distal end may be reconfigured from the first configuration to a second configuration which is shaped to contact and follow the tissue region and the post nasal nerve may then be ablated via the distal end. Ablation may be performed using various mechanisms, such as cryotherapy, and optionally under direct visualization.

    摘要翻译： 本文公开了用于治疗诸如鼻炎的病症的装置和方法，其中探针轴的远端通过鼻腔引入，其中远端具有末端执行器，其具有低轮廓的第一构造，其具有被成形为操纵组织内的组织 鼻腔。 远端可以定位在具有与中鼻甲或下鼻甲相连的鼻后神经的组织区域附近。 一旦适当地定位，远端可以从第一构型重新配置到第二构型，其被成形为接触和跟随组织区域，并且鼻后神经可以经由远端被烧蚀。 可以使用诸如冷冻治疗的各种机制进行消融，并且可选地直接观察。

    Device and Methods for Targeting of Transcranial Ultrasound Neuromodulation by Automated Transcranial Doppler Imaging
    34.
    发明申请
    Device and Methods for Targeting of Transcranial Ultrasound Neuromodulation by Automated Transcranial Doppler Imaging 审中-公开
    通过自动经颅多普勒成像定位经颅超声神经调节的装置和方法

    公开(公告)号：US20150151142A1

    公开(公告)日：2015-06-04

    申请号：US14501523

    申请日：2014-09-30

    申请人： THYNC, INC. ,  UNIVERSITY OF WASHINGTON

    发明人： William J. TYLER ,  Pierre MOURAD ,  Daniel Z. WETMORE

    IPC分类号： A61N7/00 ,  A61B8/00 ,  A61B5/0476 ,  A61B5/1455 ,  A61B5/055 ,  A61B5/053 ,  A61B6/03 ,  A61B8/08 ,  A61B5/0205

    CPC分类号： A61N7/00 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/024 ,  A61B5/0476 ,  A61B5/0533 ,  A61B5/055 ,  A61B5/14551 ,  A61B6/03 ,  A61B8/06 ,  A61B8/0808 ,  A61B8/0891 ,  A61B8/4477 ,  A61B8/466 ,  A61B8/481 ,  A61B8/488 ,  A61B2090/378 ,  A61N7/02 ,  A61N2007/0026 ,  A61N2007/003 ,  A61N2007/0073

    摘要： Methods and systems for transcranial ultrasound neuromodulation as well as targeting such neuromodulation in the brain are disclosed. Automated transcranial Doppler imaging (aTCD) of blood flow in the brain is performed and one or more 3-dimensional maps of the neurovasculature are generated. Ultrasound energy is delivered transcranially in conjunction to induce neuromodulation. One or more brain regions for neuromodulation are targeted by using brain blood vessel landmarks identified by aTCD components. The landmarks are used for initial targeting of the neuromodulation to one or more brain regions of interest and/or for maintaining neuromodulation targeting despite user or device movements. Acoustic contrast agents may be employed to generate broadband ultrasound waves locally at the site of target cells. Transcranial ultrasound neuromodulation may be achieved by having confocal ultrasound waves differing in acoustic frequency by a frequency effective for neuromodulation interfere to generate vibrational forces in the brain that induce neuromodulation.

    摘要翻译： 公开了用于经颅超声神经调节的方法和系统以及靶向脑中的这种神经调节。 执行大脑中血流的自动经颅多普勒成像（aTCD），并产生神经血管系统的一个或多个三维图。 超声能量通过经颅传递来诱导神经调节。 用于神经调节的一个或多个脑区域通过使用由TCD组分鉴定的脑血管标志物来靶向。 地标用于将神经调节物初始靶向一个或多个感兴趣的脑区域和/或用于尽管用户或装置移动来维持神经调节靶向。 可以使用声学造影剂在靶细胞的位置局部产生宽带超声波。 经颅超声神经调节可以通过使声学频率不同的共焦超声波以对神经调节干扰有效的频率产生，从而在脑中产生诱导神经调节的振动力。

    Energetic modulation of nerves
    38.
    发明授权
    Energetic modulation of nerves 有权
    神经的能量调节

    公开(公告)号：US08992447B2

    公开(公告)日：2015-03-31

    申请号：US13523835

    申请日：2012-06-14

    申请人： Michael Gertner ,  David Perozek ,  Jimin Zhang ,  Arash Sabet

    发明人： Michael Gertner ,  David Perozek ,  Jimin Zhang ,  Arash Sabet

    IPC分类号： A61B5/05 ,  A61N7/00 ,  A61B19/00 ,  A61N7/02 ,  A61B17/00 ,  A61B18/00 ,  A61B6/00

    CPC分类号： A61N7/00 ,  A61B6/506 ,  A61B8/4245 ,  A61B8/44 ,  A61B8/485 ,  A61B90/37 ,  A61B2017/00106 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2090/374 ,  A61N7/02 ,  A61N2007/003 ,  A61N2007/0078 ,  A61N2007/0095

    摘要： A system for applying focused ultrasound energy to a nerve surrounding an artery of a patient includes a piezoelectric array comprising a plurality of piezoelectric elements, a controller configured to control at least a subset of the piezoelectric elements so that at least one of the piezoelectric elements in the subset is in a signal transmitting mode, in a signal sensing mode, or both, a first platform on which the piezoelectric elements are coupled and a second platform, wherein the second platform is configured to support at least a part of the patient, a programmable generator configured to generate output power for one or more of the piezoelectric elements, and a programmable processor configured to process a signal sensed by at least one of the piezoelectric elements.

    摘要翻译： 将聚焦超声能量施加到患者动脉周围的神经的系统包括包括多个压电元件的压电阵列，控制器，被配置为控制压电元件的至少一个子集，使得至少一个压电元件 所述子集处于信号传输模式，信号感测模式或两者中，所述压电元件耦合在其上的第一平台和第二平台，其中所述第二平台被配置为支撑所述患者的至少一部分， 可编程发生器被配置为产生一个或多个压电元件的输出功率，以及被配置为处理由至少一个压电元件感测的信号的可编程处理器。