Depolymerized glycosaminoglycan from Thelenota ananas and preparation method thereof
    52.
    发明授权
    Depolymerized glycosaminoglycan from Thelenota ananas and preparation method thereof 有权
    来自Thelenota ananas的解聚糖胺聚糖及其制备方法

    公开(公告)号:US08809300B2

    公开(公告)日:2014-08-19

    申请号:US13512142

    申请日:2010-10-25

    CPC classification number: A61K31/737 A61K31/726 C08B37/0063

    Abstract: Disclosed is a depolymerized glycosaminoglycan from Thelenota ananas (dTHG), weight average molecular weight of which is about 8000˜20000 Da, and monosaccharide components of which are acetylgalactosamine (GalNAc), glucuronic acid (GlcUA), fucose (Fuc) or their sulfates (expressed as —OSO3−), in which molar ratio of GalNAc:GlcUA:Fuc:—OSO3− is about 1:(1±0.3):(1±0.3):(3.5±0.5). Said dTHG is a potent endogenous inhibitor of factor X, which has good anticoagulant and antithrombotic activity, and can be used for the prevention and/or treatment of thrombotic diseases. Also provided is a method for preparing said dTHG, which comprises steps of 1) extracting and obtaining fucosylated glycosaminoglycan (THG) from the body wall of Thelenota ananas; 2) depolymerizing THG to obtain dTHG by method of peroxide depolymerization or method of peroxide depolymerization catalyzed by catalyst of the fourth period transition metal ions; 3) removing impurities with lower and/or higher molecular weight in dTHG.

    Abstract translation: 公开了来自Thelenota ananas(dTHG)的解聚糖胺聚糖(dTHG),其重均分子量为约8000-20000Da,其单糖组分为乙酰半乳糖胺(GalNAc),葡糖醛酸(GlcUA),岩藻糖(Fuc)或其硫酸盐 表达为-OSO3-),其中GalNAc:GlcUA:Fuc:-OSO3-的摩尔比为约1:(1±0.3):(1±0.3):(3.5±0.5)。 所述dTHG是一种有效的因子X的内源性抑制剂,其具有良好的抗凝血和抗血栓形成活性,可用于预防和/或治疗血栓性疾病。 还提供了一种制备所述dTHG的方法,其包括以下步骤:1)从Thelenota ananas的体壁提取并获得岩藻糖基化的糖胺聚糖(THG); 2)解聚THG,通过过氧化物解聚法或第四周期过渡金属离子催化剂催化的过氧化物解聚方法得到dTHG; 3)去除dTHG中具有较低和/或更高分子量的杂质。

    Liquid crystal display (LCD) system and method
    54.
    发明授权
    Liquid crystal display (LCD) system and method 有权
    液晶显示(LCD)系统及方法

    公开(公告)号:US08638407B2

    公开(公告)日:2014-01-28

    申请号:US12768638

    申请日:2010-04-27

    Applicant: Xiao Lin Yu

    Inventor: Xiao Lin Yu

    Abstract: A liquid crystal display (LCD) system is provided. The LCD system includes a light-passable plate, an LCD panel and a controller. The light-passable plate is configured to allow natural light to pass through the light-passable plate; and the LCD panel is coupled to the light-passable plate and is configured to receive the natural light passing through the light-passable plate. Further, the controller is coupled to the LCD panel to control the LCD panel such that the natural light passing through the light-passable plate is used as backlight for operation of the LCD panel. The light-passable plate structurally supports the LCD panel in addition to providing the natural light to the LCD panel.

    Abstract translation: 提供液晶显示(LCD)系统。 LCD系统包括可光通过的板,LCD面板和控制器。 光通过的板被配置为允许自然光通过可光通过的板; 并且所述LCD面板被耦合到所述光通过板,并且被配置为接收通过所述光通过板的自然光。 此外,控制器耦合到LCD面板以控制LCD面板,使得通过可透光板的自然光用作LCD面板的操作的背光。 除了向LCD面板提供自然光之外,透光板在结构上支撑LCD面板。

    Light-emitting diodes on concave texture substrate
    55.
    发明授权
    Light-emitting diodes on concave texture substrate 有权
    凹面纹理基板上的发光二极管

    公开(公告)号:US08629465B2

    公开(公告)日:2014-01-14

    申请号:US13358327

    申请日:2012-01-25

    CPC classification number: H01L33/48 H01L33/20 H01L33/24

    Abstract: A semiconductor device having light-emitting diodes (LEDs) formed on a concave textured substrate is provided. A substrate is patterned and etched to form recesses. A separation layer is formed along the bottom of the recesses. An LED structure is formed along the sidewalls and, optionally, along the surface of the substrate between adjacent recesses. In these embodiments, the surface area of the LED structure is increased as compared to a planar surface. In another embodiment, the LED structure is formed within the recesses such that the bottom contact layer is non-conformal to the topology of the recesses. In these embodiments, the recesses in a silicon substrate result in a cubic structure in the bottom contact layer, such as an n-GaN layer, which has a non-polar characteristic and exhibits higher external quantum efficiency.

    Abstract translation: 提供了一种形成在凹面纹理基板上的发光二极管(LED)的半导体器件。 对衬底进行图案化和蚀刻以形成凹陷。 沿着凹部的底部形成分离层。 沿着侧壁和任选地沿着相邻凹部之间的基板的表面形成LED结构。 在这些实施例中,与平面表面相比,LED结构的表面积增加。 在另一个实施例中,LED结构形成在凹部内,使得底部接触层与凹部的拓扑不一致。 在这些实施例中,硅衬底中的凹槽导致底接触层中的立方结构,例如具有非极性特性并且表现出更高外部量子效率的n-GaN层。

    Through silicon via (TSV) isolation structures for noise reduction in 3D integrated circuit
    57.
    发明授权
    Through silicon via (TSV) isolation structures for noise reduction in 3D integrated circuit 有权
    通过硅通孔(TSV)隔离结构降低3D集成电路

    公开(公告)号:US08546953B2

    公开(公告)日:2013-10-01

    申请号:US13324405

    申请日:2011-12-13

    CPC classification number: H01L23/481 H01L2924/0002 H01L2924/00

    Abstract: Through silicon via (TSV) isolation structures are provided and suppress electrical noise such as may be propagated through a semiconductor substrate when caused by a signal carrying active TSV such as used in 3D integrated circuit packaging. The isolation TSV structures are surrounded by an oxide liner and surrounding dopant impurity regions. The surrounding dopant impurity regions may be P-type dopant impurity regions that are coupled to ground or N-type dopant impurity regions that may advantageously be coupled to VDD. The TSV isolation structure is advantageously disposed between an active, signal carrying TSV and active semiconductor devices and the TSV isolation structures may be formed in an array that isolates an active, signal carrying TSV structure from active semiconductor devices.

    Abstract translation: 提供通过硅通孔(TSV)隔离结构,并且抑制诸如在由3D集成电路封装中使用的携带有源TSV的信号引起的时候可能传播通过半导体衬底的电噪声。 隔离TSV结构被氧化物衬垫和周围的掺杂剂杂质区包围。 周围的掺杂剂杂质区域可以是耦合到接地的P型掺杂剂杂质区域或者可以有利地连接到VDD的N型掺杂剂杂质区域。 TSV隔离结构有利地设置在有源信号承载TSV和有源半导体器件之间,并且TSV隔离结构可以形成为将有源信号传输TSV结构与有源半导体器件隔离的阵列。

    AUTOMOBILE BLIND SPOT DETECTION SYSTEM AND METHOD

    公开(公告)号:US20130176145A1

    公开(公告)日:2013-07-11

    申请号:US13346783

    申请日:2012-01-10

    Applicant: Xiao Lin Yu

    Inventor: Xiao Lin Yu

    Abstract: A system is provided for detecting a blind spot for a driver of a vehicle. The system includes a side mirror. The side mirror is arranged on a body of the vehicle and includes a side mirror body, a mirror, and a supporting structure. The system also includes a detection system. The detection system is physically coupled with the side mirror to detect an object in a detection zone of the detection system. The detection zone covers the blind spot, and the detection system includes a detection module, an alert indicator, and a control module. The detection module includes at least one of a transmitter and a receiver, and the alert indicator is configured to send an alert light to the driver at a predetermined angle such that the alert light does not interfere with drivers of other vehicles close to the vehicle.

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