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81.发明申请公开(公告)号：US20190072464A1
公开(公告)日：2019-03-07
申请号：US16119253
申请日：2018-08-31
摘要： Systems and methods are described to concentrate a remote sample for analysis. A sample concentration system embodiment includes, but is not limited to, a plurality of valves including at least a first valve, a second valve, and a third valve; a plurality of columns including at least a first column and a second column, the first column fluidically coupled to the first valve, the second column fluidically coupled to the second valve; and a flow meter coupled with the third valve, the flow meter fluidically coupled with each of the first column and the second column when the plurality of valves is in a first flow path configuration to measure an amount of the liquid sample passed through the first column and the second column, wherein the plurality of valves includes a second flow path configuration and a third flow path configuration.
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公开(公告)号：US10190147B1
公开(公告)日：2019-01-29
申请号：US15198024
申请日：2016-06-30
发明人： Daniel R. Wiederin
摘要： A system is provided that includes a tray having a number of compartments for holding liquid samples and partitioning the liquid samples from one another. The liquid samples are prepared by adding an indicator configured to produce a characteristic change in light from the liquid samples when a target microbe metabolizes the indicator while the liquid samples are incubated. The system also includes a light sensor for sensing light from the liquid samples held in the tray while the plurality of liquid samples is incubated. The system further includes a processor coupled with the light sensor and configured to analyze the light from the liquid samples while the liquid samples are incubated to detect the characteristic change in light from one or more of the liquid samples if the target microbe is present in the liquid samples.
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公开(公告)号：US10073106B1
公开(公告)日：2018-09-11
申请号：US15713054
申请日：2017-09-22
发明人： Tyler Yost , David Diaz , Daniel R. Wiederin , Kevin Hahn
CPC分类号： G01N35/00732 , G01N35/1011 , G01N2035/00752 , G01N2035/00831 , G01N2035/00841 , G01N2035/00851 , G01N2035/00881 , G06K7/10564 , G06K7/1417 , G06K19/06037
摘要： A sample identification system for an automated sampling and dispensing device is described. In an example implementation, the sample identification system includes a sample probe configured to contact a sample positioned within a sample vessel. Further, the sample identification system includes an identifier capture device configured to measure a sample identifier associated with the sample vessel and generate a data signal in response thereto, where the data signal corresponds to an identity of the at least one sample. During operation, the identifier capture device scans a sample holder, a sample vessel, or a table top of the automated sampling and dispensing device to measure the sample identifier and to generate the data signal in response thereto.
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公开(公告)号：US09953822B1
公开(公告)日：2018-04-24
申请号：US14740472
申请日：2015-06-16
发明人： Daniel R. Wiederin , Paul Field
CPC分类号： G01J3/443 , G01N30/7253 , G01N30/74
摘要： A system includes a sample selector device, a chromatographic column selectively connectable to the sample selector device, and a spectrometry analysis device selectively connectable to the sample selector device. The sample selector device is configured to supply multiple individual samples to the chromatographic column to separate components of the individual samples. The sample selector device is also configured to store the separated components of the individual samples. The sample selector device is further configured to supply the separated components of the individual samples to the spectrometry analysis device. In embodiments of the disclosure, the components of the individual samples can be chromatographically separated while the spectrometry analysis device is offline.
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公开(公告)号：US20180017472A1
公开(公告)日：2018-01-18
申请号：US15547669
申请日：2016-02-08
发明人： Daniel R. Wiederin
摘要： This disclosure is directed to a system and method relevant to sampling halosilanes or other water-reactive samples. In embodiments, a system for hydrolyzing samples includes a container with a receiving liquid (e.g., an HF solution) contained therein and an actuator coupled with the container. The actuator can be configured to rotate the container, thereby inducing a vortex in the receiving liquid. The system further includes a sample tube configured to direct a halosilane sample into the vortexed receiving liquid. The sample tube can be oriented to release the sample in a flow direction of the vortexed receiving liquid.
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公开(公告)号：US09752987B1
公开(公告)日：2017-09-05
申请号：US14635887
申请日：2015-03-02
发明人： Daniel R. Wiederin , Austin Schultz
CPC分类号： H02P25/188 , B01J4/02 , B01J19/18 , B01J2219/00182 , B63H21/14 , B63H21/20 , B63H23/10 , B63H2021/202 , B63H2021/205 , C01B6/06 , C01B6/10 , G01N21/714 , G01N21/73 , H02K3/28 , H02K7/183 , H02K16/04 , H02K19/16 , H02K21/024 , H02P31/00 , Y02T70/5236 , Y10S903/906
摘要： The present disclosure is directed to a system and a method for hydride generation. In some embodiments, the system includes an assembly for introducing hydride generation reagents into a mixing path or mixing container, where the assembly includes first chamber configured to contain a first hydride generation reagent and a second chamber configured to contain a second hydride generation reagent. A first plunger is configured to translate within the first chamber and cause a displacement of the first hydride generation reagent, and a second plunger is configured to translate within the second chamber and cause a displacement of the second hydride generation reagent. The assembly further includes base coupling the first plunger and the second plunger together.
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公开(公告)号：US20160305917A1
公开(公告)日：2016-10-20
申请号：US15192464
申请日：2016-06-24
发明人： David Diaz , Jonathan Hein , Kyle W. Uhlmeyer , Daniel R. Wiederin , Tyler Yost , Kevin Wiederin
摘要： Systems and methods are described to determine whether a sample transmitted through a transfer line from a remote sampling system contains a suitable sample to analyze by an analysis system. A system embodiment includes, but is not limited to, a sample receiving line configured to receive a liquid segment a first detector configured to detect the liquid segment at a first location in the sample receiving line; a second detector configured to detect the liquid segment at a second location in the sample receiving line downstream from the first location; and a controller configured to register a continuous liquid segment in the sample receiving line when the first detector and the second detector match detection states prior to the controller registering a change of state of the first detector.
摘要翻译： 描述系统和方法以确定通过远程采样系统的传输线传输的样本是否包含合适的样本以供分析系统分析。 系统实施例包括但不限于被配置为接收液体段的样品接收管线，第一检测器被配置为检测样品接收管线中的第一位置处的液体段; 第二检测器，被配置为在所述第一位置下游的所述样本接收线中的第二位置处检测所述液体段; 以及控制器，其被配置为当所述第一检测器和所述第二检测器在所述控制器记录所述第一检测器的状态改变之前匹配检测状态时，在所述样本接收线中登记连续液体段。
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公开(公告)号：US09406490B1
公开(公告)日：2016-08-02
申请号：US14703828
申请日：2015-05-04
CPC分类号： H01J49/105 , B05B14/45 , H01J49/0031 , H01J49/0077 , H01J49/045 , H01J49/145
摘要： A system for determining an analyte by inductively coupled plasma mass spectrometry (ICPMS) includes a sample introduction device having a heated cyclonic spray chamber. The system is configured to introduce sample that includes a metal and/or a metalloid having an organic interferent. The system also includes an inductively coupled plasma mass spectrometry device with a collision/reaction cell configured to receive a mixture of gases including both ammonia and hydrogen. A method includes introducing a sample to plasma to produce a characteristic spectrum associated with an elemental composition of the sample. The method also includes introducing both ammonia and hydrogen to a collision/reaction cell to remove carbon-based interferences to detection of the sample prior to determining the elemental composition of the sample.
摘要翻译： 通过电感耦合等离子体质谱法（ICPMS）确定分析物的系统包括具有加热旋风喷雾室的样品引入装置。 该系统被配置为引入包含具有有机干扰物的金属和/或准金属的样品。 该系统还包括电感耦合等离子体质谱装置，其中碰撞/反应池配置成接收包括氨和氢的气体混合物。 一种方法包括将样品引入等离子体以产生与样品的元素组成相关的特征谱。 该方法还包括将氨和氢引入到碰撞/反应池中，以在确定样品的元素组成之前除去对基于样品的检测的碳基干扰。
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公开(公告)号：US09146182B1
公开(公告)日：2015-09-29
申请号：US14163311
申请日：2014-01-24
IPC分类号： F16K11/074 , G01N30/20 , G01N1/28
CPC分类号： G01N30/20 , G01N2030/201 , G01N2030/202 , G01N2030/207 , Y10T137/86863
摘要： Valve assemblies are described that provide flow paths in substantially indirect opposition for fluids injected into the valve assemblies for mixing. A valve assembly includes a first valve member having ports configured to receive a first fluid and a second fluid. The valve assembly also includes a second valve member coupled adjacent to the first valve member. The valve assembly defines a first flow path for the first fluid and a second flow path for the second fluid. The first flow path extends from one of the ports of the first valve member toward an interface between the first valve member and the second valve member, and the second flow path extends from a channel defined by the second valve member toward the interface between the first valve member and the second valve member. The second flow path is in substantially indirect opposition to the first flow path.
摘要翻译： 描述了阀组件，其为注入到阀组件中以用于混合的流体提供基本上间接的相反的流动路径。 阀组件包括具有构造成容纳第一流体和第二流体的端口的第一阀构件。 阀组件还包括与第一阀构件相邻联接的第二阀构件。 阀组件限定用于第一流体的第一流动路径和用于第二流体的第二流动路径。 第一流路从第一阀构件的一个端口延伸到第一阀构件和第二阀构件之间的界面，并且第二流动路径从由第二阀构件限定的通道朝向第一阀构件和第二阀构件之间的界面延伸 阀构件和第二阀构件。 第二流动路径基本上间接地与第一流动路径相反。
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公开(公告)号：US20240299928A1
公开(公告)日：2024-09-12
申请号：US18412909
申请日：2024-01-15
发明人： Daniel R. Wiederin , Austin Schultz
CPC分类号： B01L3/502 , B01L3/523 , B01L3/567 , G01N1/38 , G01N21/73 , G01N35/1097 , H01J49/0431 , B01L2200/0605 , B01L2300/024 , B01L2300/049 , B01L2300/0806 , B01L2300/0861 , B01L2300/0867 , B01L2400/0487 , B01L2400/049 , B01L2400/06 , G01N2001/386 , G01N21/71 , G01N2035/1032 , H01J49/105
摘要： Sample preparation systems and methods are described having pump control, valve configurations, and control logic that facilitate automatic, inline preparation dilutions of a sample according to at least two dilution operating modes. A system embodiment includes, but is not limited to a first pump configured to drive a carrier fluid; a second pump configured to drive a diluent; and a plurality of selection valves fluidically coupled with the first pump and the second pump, the plurality of selection valves being configured to direct fluid flows from the first pump and the second pump according to at least two modes of operation to provide a single-stage sample dilution according to a first operating mode and to provide a dual-stage sample dilution according to a second operating mode.
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