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    Balloon catheters and methods for manufacturing balloons for balloon catheters
    1.
    发明申请
    Balloon catheters and methods for manufacturing balloons for balloon catheters 审中-公开
    球囊导管及球囊导管球囊的制造方法

    公开(公告)号：US20050228428A1

    公开(公告)日：2005-10-13

    申请号：US10819469

    申请日：2004-04-07

    申请人： Afsar Ali ,  Daniel Horn ,  Jan Weber ,  Scott Schewe

    发明人： Afsar Ali ,  Daniel Horn ,  Jan Weber ,  Scott Schewe

    IPC分类号： A61F2/958 ,  A61M25/00 ,  B29C35/08 ,  B29C49/00 ,  B29C49/14 ,  B29C55/00 ,  A61M29/00 ,  B29C49/64

    CPC分类号： A61M25/1027 ,  A61M2025/1063 ,  B29C49/00 ,  B29C2035/0838 ,  B29C2035/0855 ,  B29C2049/0089 ,  B29C2791/001 ,  B29C2791/009 ,  B29K2105/258 ,  B29L2031/7542

    摘要： Catheters, balloons, and methods of manufacturing balloons for balloon catheters using lasers are disclosed. A catheter with a shaft sized for use with a 0.014 inch guide wire includes a polymeric balloon having a body portion with an inflated outer diameter of more than 6 millimeters. An inflatable balloon includes an inflated outer diameter to inner waist diameter ratio of 12.5 to 1. An inflatable polymeric balloon that has a body portion with two regions that have different molecular orientations is also provided. A method of processing an elongate polymeric material includes heating a portion of the polymeric material with a laser while longitudinally stretching the portion of the polymeric material. A method of manufacturing a balloon includes heating and longitudinally stretching a first and second portion of an elongate polymeric tube to form first and second end portion. The remaining body portion is radially expanded to form the balloon.

    摘要翻译： 公开了使用激光器的球囊导管制造气球的导管，球囊和方法。 具有尺寸与0.014英寸导丝一起使用的轴的导管包括具有膨胀外径大于6毫米的主体部分的聚合物球囊。 可充气气囊包括膨胀的外径至内腰直径比为12.5:1。还提供具有主体部分的充气聚合球囊，其具有不同分子取向的两个区域。 处理细长聚合材料的方法包括在纵向拉伸聚合材料的一部分的同时用激光加热聚合材料的一部分。 制造球囊的方法包括加热并纵向拉伸细长聚合物管的第一和第二部分以形成第一和第二端部。 剩余的主体部分被径向扩张以形成气球。

    Balloon catheters and methods for manufacturing balloons for balloon catheters
    3.
    发明授权
    Balloon catheters and methods for manufacturing balloons for balloon catheters 有权
    球囊导管及球囊导管球囊的制造方法

    公开(公告)号：US08034280B2

    公开(公告)日：2011-10-11

    申请号：US12552223

    申请日：2009-09-01

    申请人： Afsar Ali ,  Daniel J. Horn ,  Jan Weber ,  Scott Schewe

    发明人： Afsar Ali ,  Daniel J. Horn ,  Jan Weber ,  Scott Schewe

    IPC分类号： B29C55/00 ,  H05B6/00 ,  B29C39/02 ,  D02J1/06 ,  A61M29/00 ,  A61M29/02

    CPC分类号： A61M25/1027 ,  A61M2025/1063 ,  B29C49/00 ,  B29C2035/0838 ,  B29C2035/0855 ,  B29C2049/0089 ,  B29C2791/001 ,  B29C2791/009 ,  B29K2105/258 ,  B29L2031/7542

    摘要： Catheters, balloons, and methods of manufacturing balloons for balloon catheters using lasers are disclosed. A catheter with a shaft sized for use with a 0.014 inch guide wire includes a polymeric balloon having a body portion with an inflated outer diameter of more than 6 millimeters. An inflatable balloon includes an inflated outer diameter to inner waist diameter ratio of 12.5 to 1. An inflatable polymeric balloon that has a body portion with two regions that have different molecular orientations is also provided. A method of processing an elongate polymeric material includes heating a portion of the polymeric material with a laser while longitudinally stretching the portion of the polymeric material. A method of manufacturing a balloon includes heating and longitudinally stretching a first and second portion of an elongate polymeric tube to form first and second end portion. The remaining body portion is radially expanded to form the balloon.

    摘要翻译： 公开了使用激光器的球囊导管制造气球的导管，球囊和方法。 具有尺寸与0.014英寸导丝一起使用的轴的导管包括具有膨胀外径大于6毫米的主体部分的聚合物球囊。 可充气气囊包括膨胀的外径至内腰直径比为12.5:1。还提供具有主体部分的充气聚合球囊，其具有不同分子取向的两个区域。 处理细长聚合材料的方法包括在纵向拉伸聚合材料的一部分的同时用激光加热聚合材料的一部分。 制造球囊的方法包括加热并纵向拉伸细长聚合物管的第一和第二部分以形成第一和第二端部。 剩余的主体部分被径向扩张以形成气球。

    INTERNAL MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH A SOURCE OF ELECTRICAL POWER
    10.
    发明申请
    INTERNAL MEDICAL DEVICES FOR DELIVERY OF THERAPEUTIC AGENT IN CONJUNCTION WITH A SOURCE OF ELECTRICAL POWER 有权
    用于与电力来源连接的治疗药物的内部医疗装置

    公开(公告)号：US20110046539A1

    公开(公告)日：2011-02-24

    申请号：US12939363

    申请日：2010-11-04

    申请人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    发明人： Liliana Atanasoska ,  Thomas J. Holman ,  Jan Weber ,  Robert Warner ,  Scott Schewe

    IPC分类号： A61N1/30

    CPC分类号： A61N1/325 ,  A61N1/05 ,  A61N1/306 ,  A61N1/327

    摘要： The invention generally relates to internal (e.g., implantable, insertable, etc.) drug delivery devices which contain the following: (a) one or more sources of one or more therapeutic agents; (b) one or more first electrodes, (c) one or more second electrodes and (d) one or more power sources for applying voltages across the first and second electrodes. The power sources may be adapted, for example, to promote electrically assisted therapeutic agent delivery within a subject, including electroporation and/or iontophoresis. In one aspect of the invention, the first and second electrodes are adapted to have tissue of a subject positioned between them upon deployment of the medical device within the subject, such that an electric field may be generated, which is directed into the tissue. Furthermore, the therapeutic agent sources are adapted to introduce the therapeutic agents into the electric field. In another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of ion-conductive polymers and one or more types of charged therapeutic agents. In yet another aspect, the therapeutic agent sources are polymeric regions that contain one or more types of electrically conductive polymers and one or more types of charged therapeutic agents.

    摘要翻译： 本发明一般涉及含有以下物质的内部（例如，可植入，可插入等）药物递送装置：（a）一种或多种一种或多种治疗剂来源; （b）一个或多个第一电极，（c）一个或多个第二电极和（d）用于在第一和第二电极上施加电压的一个或多个电源。 电源可以适应于例如促进受试者内的电辅助治疗剂递送，包括电穿孔和/或离子电渗疗法。 在本发明的一个方面中，第一和第二电极适于在医疗装置在受试者内展开时使被检体的组织位于它们之间，使得可以产生被引导到组织中的电场。 此外，治疗剂源适于将治疗剂引入电场。 另一方面，治疗剂来源是含有一种或多种类型的离子导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。 在另一方面，治疗剂来源是含有一种或多种类型的导电聚合物和一种或多种类型的带电治疗剂的聚合物区域。