公开(公告)号：US20230320619A1

公开(公告)日：2023-10-12

申请号：US18031668

申请日：2021-10-14

Applicant: IMEC VZW

Inventor： Ahmed TAHER ,  Benjamin JONES ,  Peter PEUMANS

IPC: A61B5/08 ,  A61B5/091 ,  G01N1/22

CPC classification number: A61B5/082 ,  A61B5/091 ,  G01N1/2208 ,  G01N2001/2244

Abstract: A collecting device (200) for collecting airborne particles comprises: a first (202) and second layer (220) spaced apart for forming a particle collection chamber (240) therebetween, wherein inlets (210) extend through the first layer (202) for transporting a flow of air into the particle collection chamber (240); wherein ends (214) of the inlets (210) face a first surface (222) of the second layer (220) for capturing airborne particles by impaction; wherein outlets (230) extend through the second layer (220) for transporting the flow of air out of the particle collection chamber (240); wherein the inlets (210) and outlets (230) are staggered such that the center axes of the inlets (210) and outlets (230) are displaced from each other; wherein the flow of air experiences a pressure drop lower than 3 kPa at a flow rate of 0.5 liters per second, when the flow of air passes the collecting device (200).

公开(公告)号：US20220062850A1

公开(公告)日：2022-03-03

申请号：US17416465

申请日：2019-12-16

Applicant: IMEC VZW ,  Katholieke Universiteit Leuven

Inventor： Peter PEUMANS ,  Ahmed TAHER ,  Nicolas VERGAUWE ,  Benjamin JONES

IPC: B01J19/00 ,  B01L3/00

Abstract: The present invention provides a micro-reactor (1) adapted to host chemical reactions having at least one microfluidic layer, said micro-reactor (1) comprising a fluid inlet (2) and a fluid outlet (3); a plurality of micro-reaction chambers (10) arranged in rows (7) and columns (6), each micro-reaction chamber comprising a chamber inlet (10a) and a chamber outlet (10b); a plurality of supply channels (4) for supplying fluid to from said fluid inlet (2) to said micro-reaction chambers (10) and further arranged for draining said micro-reaction chambers (10) to said fluid outlet (3), said supply channels (10) extending in a first direction (D1) along the columns (6) of micro-reaction chambers (10) and arranged such that there is one supply channel (4) between adjacent columns (6). The micro-reaction chambers (10) in the columns (6) are arranged such that the chamber inlets (10a) of a column are in fluid contact with the same supply channel (4) and the chamber outlets (10b) are in fluid contact with the supply channel (4) adjacent to the supply channel (4) arranged in fluidic contact with the chamber inlets (10a). Further, the plurality of supply channels (4) comprises a first end supply channel (4a) arranged for supplying fluid to a first end column (6a) of the micro-reaction chambers (10) and a second end supply channel (4b) arranged for draining fluid from the second, opposite, end column (6b) of said micro-reaction chambers (10); and wherein the micro-reactor (1) further comprises at least one reagent inlet (8) in fluid contact with the first end supply channel 4a and a reagent outlet (9) in fluid contact with the second end supply channel such that reagents introduced to the at least one reagent inlet (8) fill the plurality of micro-reaction chambers (10) in a second direction (D2) along the rows (7) of micro-reaction chambers (10) to the reagent outlet (9).

公开(公告)号：US20210189310A1

公开(公告)日：2021-06-24

申请号：US17128091

申请日：2020-12-19

Applicant: IMEC VZW ,  Katholieke Universiteit Leuven

Inventor： Aaron DELAHANTY ,  Dries BRAEKEN ,  Alexandru ANDREI ,  Peter PEUMANS ,  Carolina MORA LOPEZ ,  Veerle REUMERS ,  Veronique ROCHUS ,  Bart WEEKERS

IPC: C12M1/34 ,  C12N1/00

Abstract: A semiconductor cell culture device for three-dimensional cell culture comprises: a semiconductor material layer in which a cell culture portion of semiconductor material is defined, wherein the cell culture portion defines an area within the semiconductor material layer surrounded by semiconductor material, wherein the cell culture portion comprises a mesh structure having island structures being interconnected by bridge structures and defining through-pores between the island structures allowing for selective transport of cell constructs, cellular components, proteins or other large molecules through the semiconductor material layer and on opposite sides of the cell culture portion in the semiconductor material layer, and a supporting structure connected to the cell culture portion.

公开(公告)号：US20160128612A1

公开(公告)日：2016-05-12

申请号：US14934727

申请日：2015-11-06

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  IMEC VZW

Inventor： Seongho CHO ,  Peter PEUMANS ,  Woochang LEE

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/145

CPC classification number: A61B5/1455 ,  A61B5/0075 ,  A61B5/14532 ,  A61B2562/043 ,  G01N2201/12

Abstract: A spectroscopic apparatus and method for analyzing a biological material are provided. The spectroscopic apparatus may analyze a biological material which has an internal non-uniform tissue depending on a position thereof. The apparatus may include at least one detector configured to obtain respective detection spectrums corresponding to a plurality of measurement regions that are at mutually different positions of the biological material, and an information processor to determine whether the measurement regions are normal by mutually comparing the detection spectrums, or converting contribution degrees of data for a specific component of the biological material by differentiating the detection spectrums.

Abstract translation: 提供了用于分析生物材料的分光装置和方法。 分光装置可以根据其位置分析具有内部不均匀组织的生物材料。 该装置可以包括至少一个检测器，被配置为获得对应于生物材料的相互不同位置处的多个测量区域的相应检测光谱;以及信息处理器，用于通过相互比较检测光谱来确定测量区域是否正常 ，或者通过区分检测光谱来转换生物材料的特定成分的数据贡献度。

公开(公告)号：US20240165622A1

公开(公告)日：2024-05-23

申请号：US18509500

申请日：2023-11-15

Applicant: IMEC VZW

Inventor： Olivier HENRY ,  Tim STAKENBORG ,  Willem VAN ROY ,  Peter PEUMANS

IPC: B01L3/00 ,  G01N15/14

CPC classification number: B01L3/502761 ,  B01L3/502776 ,  B01L3/502792 ,  G01N15/1484 ,  B01L2200/0636 ,  B01L2200/0652 ,  B01L2200/10 ,  B01L2400/0403 ,  G01N2015/1445

Abstract: A method for monitoring a monitor material of a process, such as a manufacturing process, comprises: detecting a suspicious particle in a sample of the monitor material using an imaging system configured to image the sample using illumination light from a light source and to detect an interference pattern based on object light having interacted with the sample and reference light of the illumination light; selectively diverting the suspicious particle rom a flow of the sample to an analysis flow; activating a nucleic acid test (NAT) device, wherein said activating is triggered based on detecting of the suspicious particle in the sample; receiving by the NAT device the analysis flow comprising the suspicious particle; and subjecting the suspicious particle to a NAT analysis.
Also, an apparatus for monitoring a monitor material is provided.

公开(公告)号：US20160356720A1

公开(公告)日：2016-12-08

申请号：US15119055

申请日：2015-02-28

Applicant: Imec VZW

Inventor： Pol VAN DORPE ,  Peter PEUMANS

IPC: G01N21/65 ,  A61B5/00 ,  A61B5/1455 ,  G01N33/49 ,  A61B5/145

CPC classification number: G01N21/65 ,  A61B5/0066 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/443 ,  A61B2562/0233 ,  A61B2562/0238 ,  G01J1/0204 ,  G01J1/0425 ,  G01J1/0477 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0227 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0291 ,  G01J3/1895 ,  G01J3/26 ,  G01J3/36 ,  G01J3/44 ,  G01J2003/1213 ,  G01N33/49 ,  G01N2201/06113 ,  G01N2201/0633 ,  G01N2201/0636 ,  G02B6/0026 ,  G02B6/0031 ,  G02B6/0038 ,  G02B6/0048

Abstract: The present disclosure relates to systems, methods, and sensors configured to characterize a radiation beam. At least one embodiment relates to an optical system. The optical system includes an optical radiation guiding system. The optical radiation guiding system includes a collimator configured to collimate the radiation beam into a collimated radiation beam. The optical radiation guiding system also includes a beam shaper configured to distribute power of the collimated radiation beam over a discrete number of line shaped fields. A spectrum of the collimated radiation beam entering the beam shaper is delivered to each of the discrete number of line shaped fields. The optical system further includes a spectrometer chip. The spectrometer chip is configured to process the spectrum of the collimated radiation beam in each of the discrete number of line shaped fields coming from the beam shaper.

Abstract translation: 本公开涉及被配置为表征辐射束的系统，方法和传感器。 至少一个实施例涉及光学系统。 光学系统包括光学辐射引导系统。 光辐射引导系统包括准直器，其被配置成将辐射束准直成准直的辐射束。 光学辐射引导系统还包括光束整形器，其被配置为分布在离散数量的线状场上的准直辐射束的功率。 进入光束整形器的准直辐射束的光谱被传送到离散数量的线状场中的每一个。 光学系统还包括光谱仪芯片。 光谱仪芯片被配置为处理来自光束整形器的离散数量的线状场中的每一个中的准直辐射束的光谱。

公开(公告)号：US20230380720A1

公开(公告)日：2023-11-30

申请号：US18031662

申请日：2021-10-14

Applicant: IMEC VZW

Inventor： Peter PEUMANS ,  Benjamin JONES ,  Xavier ROTTENBERG ,  Chengxun LIU ,  Ahmed TAHER

IPC: A61B5/097 ,  A61B5/00

CPC classification number: A61B5/097 ,  A61B5/0082

Abstract: A collecting device (200) for collection of particles and presentation of collected particles for analysis comprises: a first layer (202) and a second layer (220) spaced apart for defining a particle collection chamber (240); wherein the first layer (202) is configured to receive a flow of air (104) carrying airborne particles, wherein the first layer (202) comprises a plurality of inlet nozzles (210) configured to extend through the first layer (202) for transporting the flow of air (104) therethrough; wherein the inlet nozzles (210) are configured to face a first surface (222) of the second layer (220) for capturing airborne particles in the flow of air (104) entering the particle collection chamber (240) by impaction of airborne particles; wherein the collecting device (200) is configured to provide optical access for performing a measurement, based on light, of airborne particles collected in the particle collection chamber (240).

公开(公告)号：US20170167921A1

公开(公告)日：2017-06-15

申请号：US15297720

申请日：2016-10-19

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  IMEC VZW

Inventor： Woochang LEE ,  Peter PEUMANS

IPC: G01J3/28 ,  G01J3/02 ,  A61B5/1455 ,  G01J3/42

CPC classification number: G01J3/2823 ,  A61B5/1455 ,  G01J3/0205 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/18 ,  G01J3/2803 ,  G01J3/36 ,  G01J3/42 ,  G02B6/12007

Abstract: A spectral detector includes a plurality of spectral detection units, each of the spectral detection units including an optical signal processor configured to deliver an optical signal incident to the spectral detection unit to an outside of the spectral detection unit, and a resonator configured to modulate a spectrum of an optical signal incident to the optical signal processor by interacting with the optical signal processor, at least some of the resonators of the plurality of spectral detection units having different lengths from each other, and a number of optical signal processors included in each respective spectral detection unit varying according to a length of the resonator included in the respective spectral detection unit.

公开(公告)号：US20160131523A1

公开(公告)日：2016-05-12

申请号：US14934722

申请日：2015-11-06

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  IMEC VZW

Inventor： Seongho CHO ,  Peter PEUMANS ,  Woochang LEE

IPC: G01J3/02 ,  G01J3/44

CPC classification number: G01J3/0289 ,  A61B5/0059 ,  A61B5/0075 ,  A61B5/11 ,  A61B5/14532 ,  A61B5/441 ,  A61B5/721 ,  A61B2562/0233 ,  A61B2562/04 ,  G01J3/28 ,  G01J3/44 ,  G01N21/359 ,  G01N21/65

Abstract: A spectroscopy system includes detectors configured to obtain detection spectrums of respective detection areas that are located at different positions of an object; and an information processor configured to obtain a target spectrum of a target area by using position information of the detection areas and the detection spectrums obtained by the detectors.

Abstract translation: 光谱系统包括被配置为获得位于物体的不同位置的各个检测区域的检测光谱的检测器; 以及信息处理器，被配置为通过使用由检测器获得的检测区域和检测光谱的位置信息来获得目标区域的目标光谱。