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公开(公告)号:US06979939B2
公开(公告)日:2005-12-27
申请号:US10403525
申请日:2003-04-01
Applicant: Michel Langlois , James McVea , Jean-François Houdard
Inventor: Michel Langlois , James McVea , Jean-François Houdard
CPC classification number: H01J23/033 , H01J23/005 , H01J25/10 , H01J25/12
Abstract: The present invention relates to a cooling device for an electron tube designated to amplify a high frequency signal. The invention is particularly suitable for cooling electron tubes that amplify radio frequency signals used for television or radio. The electron tube installed on a portal frame designed to hold the frame. The device includes a first hydraulic circuit inside which a first fluid circulates to cool at least part of the tube. The device also includes fluid exchanger to transfer heat transported by the first fluid to a second hydraulic circuit. The exchanger is also located on the portal frame.
Abstract translation: 本发明涉及一种用于放大高频信号的电子管冷却装置。 本发明特别适用于放大用于电视或无线电的射频信号的冷却电子管。 电子管安装在门架上,设计用于固定框架。 该装置包括第一液压回路,其中第一流体循环以冷却至少部分管。 该装置还包括用于将由第一流体输送的热量传递到第二液压回路的流体交换器。 交换机也位于门架上。
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2.Enantiomers of absolute configuration S of amide derivatives of 3-aminoquinuclidine, the process for preparing them and their application in therapy 失效
Title translation: 3-氨基奎宁环酰胺衍生物的绝对构型S的对映异构体,其制备方法及其在治疗中的应用公开(公告)号:US5237066A
公开(公告)日:1993-08-17
申请号:US760921
申请日:1991-09-17
Applicant: Nicole A. M. Dorme , Alain J. L. Renaud , Michel Langlois
Inventor: Nicole A. M. Dorme , Alain J. L. Renaud , Michel Langlois
IPC: C07D453/02
CPC classification number: C07D453/02
Abstract: Enantiomer of absolute configuration S of formula: ##STR1## where: X=O or S; andAr denotes a:* phenyl ring substituted with one, two or three C.sub.1 -C.sub.4 alkoxy groups;* phenyl ring substituted at the 2-position with a OCH.sub.3 group and at the 5-position with a halogen atom or a lower alkylcarbonyl group;* phenyl ring substituted at the 2-position with OCH.sub.3, at the 4-position with NH.sub.2 or alkylcarbonyl-NH and at the 5-position with a halogen;* 3-fluoro-2-methoxyphenyl group;* 5-pyrimidinyl group substituted at the 2-position with NH.sub.2 and in the 4-position with alkoxy or phenyloxy.These compounds are useful as medicinal products having activity in respect of gastric movements and antiemetic activity.
Abstract translation: 绝对构型的对映异构体:式中:X = O或S; 并且Ar表示被一个,两个或三个C 1 -C 4烷氧基取代的* *在2位被OCH 3基取代的苯环,在5位被卤素原子或低级烷基羰基取代; *在2位被OCH 3取代的苯环,在4位被NH 2或烷基羰基-NH取代,在5位被卤素取代; * 3-氟-2-甲氧基苯基; * 2-位被NH 2取代的5-嘧啶基,在4-位被烷氧基或苯氧基取代。 这些化合物可用作在胃运动和止吐活性方面具有活性的药用产品。
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3.3-Parahydroxyphenyl-5-methylether-2-oxazolidinone compounds 失效
Title translation: 3-对羟基苯基-5-甲基醚-2-恶唑烷酮化合物公开(公告)号:US4287351A
公开(公告)日:1981-09-01
申请号:US119073
申请日:1980-02-06
Applicant: Guy R. Bourgery , Colette A. Douzon , Jean-Francois R. Ancher , Alain P. Lacour , Patrick G. Guerret , Michel Langlois , Phillippe L. Dostert
Inventor: Guy R. Bourgery , Colette A. Douzon , Jean-Francois R. Ancher , Alain P. Lacour , Patrick G. Guerret , Michel Langlois , Phillippe L. Dostert
IPC: C07C41/03 , C07C41/26 , C07C43/178 , C07C309/73 , C07D207/08 , C07D207/26 , C07D207/277 , C07D263/16 , C07D263/20 , C07D263/24 , C07D277/14 , C07D277/24 , A61K31/42
CPC classification number: C07D207/08 , C07C309/73 , C07D207/26 , C07D207/277 , C07D263/16 , C07D263/20 , C07D263/24 , C07D277/14
Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
Abstract translation: 公开了N-芳基恶唑烷酮,恶唑烷硫醚,吡咯烷酮,吡咯烷和噻唑烷酮。 这些化合物具有抗抑郁活性。
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公开(公告)号:US07126012B2
公开(公告)日:2006-10-24
申请号:US10947757
申请日:2004-09-23
Applicant: Daniel Lesieur , Frederique Klupsch , Gerald Guillaumet , Marie-Claude Viaud , Michel Langlois , Caroline Bennejean , Pierre Renaud , Philippe Delagrange
Inventor: Daniel Lesieur , Frederique Klupsch , Gerald Guillaumet , Marie-Claude Viaud , Michel Langlois , Caroline Bennejean , Pierre Renaud , Philippe Delagrange
IPC: C07D333/52 , A61K31/385 , C07C233/05 , A61K31/165
CPC classification number: C07D207/27 , C04B35/632 , C07C233/43 , C07C233/62 , C07C233/65 , C07C237/48 , C07C271/20 , C07C275/24 , C07C323/62 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07D209/14 , C07D209/20 , C07D209/60 , C07D213/70 , C07D221/10 , C07D231/12 , C07D233/42 , C07D233/56 , C07D233/84 , C07D235/06 , C07D249/08 , C07D261/20 , C07D307/81 , C07D307/92 , C07D311/58 , C07D311/60 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/58 , C07D333/74 , C07D335/06 , C07D335/08 , C07D401/12 , C07D405/06 , C07D405/12 , C07D407/12 , C07D471/04 , C07D491/04 , C07D495/04 , C07D495/14
Abstract: The invention concerns compounds of formula (I): R-A-R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description
Abstract translation: 本发明涉及式(I)化合物:R-A-R'其中:A如说明书中所定义; R表示基团(V),(VI),(VII)或(VIII),其中E,Q,R 1,R 2,R 3 < / SUP>,v和R 4如在说明书中所定义的; R'表示 - (CH 2)2-t-R 5 - 基,其中t和R 5如描述中所定义
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5.Compounds derived from aryl carbamates, preparation thereof and uses of same 审中-公开
Title translation: 衍生自芳基氨基甲酸酯的化合物,其制备及其用途公开(公告)号:US20050267126A1
公开(公告)日:2005-12-01
申请号:US10524875
申请日:2003-08-22
Applicant: Magali Maillet , Laurent Saniere , Eric Nicolai , Dominique Potin , Michel Langlois
Inventor: Magali Maillet , Laurent Saniere , Eric Nicolai , Dominique Potin , Michel Langlois
IPC: A61P1/00 , A61P9/00 , A61P9/06 , A61P13/00 , A61P15/00 , A61P25/00 , C07D207/09 , C07D207/16 , C07D207/34 , C07D207/40 , C07D207/416 , C07D209/18 , C07D209/42 , C07D211/58 , C07D211/60 , C07D211/62 , C07D211/78 , C07D213/69 , C07D213/74 , C07D213/82 , C07D215/48 , C07D215/54 , C07D239/38 , C07D241/20 , C07D241/24 , C07D295/088 , C07D295/13 , C07D295/135 , C07D295/215 , C07D307/14 , C07D307/24 , C07D317/66 , C07D317/68 , C07D333/20 , C07D333/38 , C07D401/04 , C07D521/00 , A61K31/496 , C07D43/02
CPC classification number: C07D207/416 , C07D207/09 , C07D207/16 , C07D207/34 , C07D209/18 , C07D209/42 , C07D211/58 , C07D211/60 , C07D211/62 , C07D211/78 , C07D213/69 , C07D213/74 , C07D213/82 , C07D215/48 , C07D215/54 , C07D231/12 , C07D233/56 , C07D239/38 , C07D241/20 , C07D241/24 , C07D249/08 , C07D295/088 , C07D295/13 , C07D295/135 , C07D295/215 , C07D307/14 , C07D307/24 , C07D317/66 , C07D317/68 , C07D333/20 , C07D333/38 , C07D401/04
Abstract: The invention concerns novel compounds, preparation and uses of same, particularly therapeutic. More particularly, the invention concerns compounds derived from arylcarbamates, preparation and uses of same, particularly in the field of human or animal health. The inventive compounds are preferably ligands of serotoninergic 5-HT4 receptors, and can therefore be used in the therapeutic or prophylactic treatment of any disorder involving a 5-HT4 receptor. The invention also relates to pharmaceutical compositions comprising such compounds, preparation and uses thereof, and treatment methods using said compounds.
Abstract translation: 本发明涉及新型化合物,其制备和用途,特别是治疗性的。 更具体地,本发明涉及衍生自芳基氨基甲酸酯的化合物,其制备方法及其用途,特别是在人或动物健康领域。 本发明化合物优选为5-羟色胺能5-HT 4受体的配体,因此可用于治疗或预防性治疗涉及5-HT4受体的任何疾病。 本发明还涉及包含这些化合物的药物组合物,其制备和用途以及使用所述化合物的治疗方法。
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公开(公告)号:US20050124682A1
公开(公告)日:2005-06-09
申请号:US10948410
申请日:2004-09-23
Applicant: Daniel Lesieur , Frederique Klupsch , Gerald Guillaumet , Marie-Claude Viaud , Michel Langlois , Caroline Bennejean , Pierre Renard , Philippe Delagrange
Inventor: Daniel Lesieur , Frederique Klupsch , Gerald Guillaumet , Marie-Claude Viaud , Michel Langlois , Caroline Bennejean , Pierre Renard , Philippe Delagrange
IPC: C07D295/12 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/17 , A61K31/18 , A61K31/19 , A61K31/27 , A61K31/341 , A61K31/343 , A61K31/352 , A61K31/357 , A61K31/381 , A61K31/382 , A61K31/4025 , A61K31/403 , A61K31/404 , A61K31/4045 , A61K31/405 , A61K31/4184 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/436 , A61K31/4365 , A61K31/437 , A61K31/4402 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61K31/4453 , A61K31/453 , A61K31/454 , A61K31/473 , A61K31/5355 , A61K31/5375 , A61K31/5377 , A61K31/55 , A61P1/00 , A61P3/06 , A61P3/10 , A61P5/02 , A61P9/00 , A61P15/08 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P35/00 , A61P43/00 , C07C233/36 , C07C233/40 , C07C233/43 , C07C233/62 , C07C233/65 , C07C237/48 , C07C271/20 , C07C271/30 , C07C275/24 , C07C275/40 , C07C311/46 , C07C317/32 , C07C323/40 , C07C323/41 , C07C323/44 , C07C323/62 , C07D207/26 , C07D207/27 , C07D209/08 , C07D209/14 , C07D209/16 , C07D209/18 , C07D209/20 , C07D209/60 , C07D209/90 , C07D213/70 , C07D221/08 , C07D221/10 , C07D233/42 , C07D233/84 , C07D235/06 , C07D235/14 , C07D261/20 , C07D295/18 , C07D307/68 , C07D307/77 , C07D307/81 , C07D307/92 , C07D311/58 , C07D311/60 , C07D311/92 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/40 , C07D333/50 , C07D333/56 , C07D333/58 , C07D333/74 , C07D335/06 , C07D335/08 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D407/12 , C07D409/06 , C07D471/04 , C07D471/14 , C07D491/04 , C07D491/048 , C07D491/052 , C07D493/04 , C07D495/04 , C07D495/14 , C07D521/00 , C07D209/42
CPC classification number: C07D207/27 , C04B35/632 , C07C233/43 , C07C233/62 , C07C233/65 , C07C237/48 , C07C271/20 , C07C275/24 , C07C323/62 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07D209/14 , C07D209/20 , C07D209/60 , C07D213/70 , C07D221/10 , C07D231/12 , C07D233/42 , C07D233/56 , C07D233/84 , C07D235/06 , C07D249/08 , C07D261/20 , C07D307/81 , C07D307/92 , C07D311/58 , C07D311/60 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/58 , C07D333/74 , C07D335/06 , C07D335/08 , C07D401/12 , C07D405/06 , C07D405/12 , C07D407/12 , C07D471/04 , C07D491/04 , C07D495/04 , C07D495/14
Abstract: The invention concerns compounds of formula (I): R-A-R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
Abstract translation: 本发明涉及式(I)化合物:R-A-R'其中:A如说明书中所定义; R表示基团(V),(VI),(VII)或(VIII),其中E,Q,R 1,R 2,R 3 < / SUP>,v和R 4如在说明书中所定义的; R'表示 - (CH 2)2-t-R 5 - 基,其中t和R 5如说明书中所定义。
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公开(公告)号:US20050059729A1
公开(公告)日:2005-03-17
申请号:US10947757
申请日:2004-09-23
Applicant: Daniel Lesieur , Frederique Klupsch , Gerald Guillaumet , Marie-Claude Viaud , Michel Langlois , Caroline Bennejean , Pierre Renard , Philippe Delagrange
Inventor: Daniel Lesieur , Frederique Klupsch , Gerald Guillaumet , Marie-Claude Viaud , Michel Langlois , Caroline Bennejean , Pierre Renard , Philippe Delagrange
IPC: C07D295/12 , A61K31/16 , A61K31/165 , A61K31/166 , A61K31/17 , A61K31/18 , A61K31/19 , A61K31/27 , A61K31/341 , A61K31/343 , A61K31/352 , A61K31/357 , A61K31/381 , A61K31/382 , A61K31/4025 , A61K31/403 , A61K31/404 , A61K31/4045 , A61K31/405 , A61K31/4184 , A61K31/423 , A61K31/435 , A61K31/4355 , A61K31/436 , A61K31/4365 , A61K31/437 , A61K31/4402 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61K31/4453 , A61K31/453 , A61K31/454 , A61K31/473 , A61K31/5355 , A61K31/5375 , A61K31/5377 , A61K31/55 , A61P1/00 , A61P3/06 , A61P3/10 , A61P5/02 , A61P9/00 , A61P15/08 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/08 , A61P25/16 , A61P25/18 , A61P25/20 , A61P25/22 , A61P25/24 , A61P25/28 , A61P35/00 , A61P43/00 , C07C233/36 , C07C233/40 , C07C233/43 , C07C233/62 , C07C233/65 , C07C237/48 , C07C271/20 , C07C271/30 , C07C275/24 , C07C275/40 , C07C311/46 , C07C317/32 , C07C323/40 , C07C323/41 , C07C323/44 , C07C323/62 , C07D207/26 , C07D207/27 , C07D209/08 , C07D209/14 , C07D209/16 , C07D209/18 , C07D209/20 , C07D209/60 , C07D209/90 , C07D213/70 , C07D221/08 , C07D221/10 , C07D233/42 , C07D233/84 , C07D235/06 , C07D235/14 , C07D261/20 , C07D295/18 , C07D307/68 , C07D307/77 , C07D307/81 , C07D307/92 , C07D311/58 , C07D311/60 , C07D311/92 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/40 , C07D333/50 , C07D333/56 , C07D333/58 , C07D333/74 , C07D335/06 , C07D335/08 , C07D401/12 , C07D405/04 , C07D405/06 , C07D405/12 , C07D407/12 , C07D409/06 , C07D471/04 , C07D471/14 , C07D491/04 , C07D491/048 , C07D491/052 , C07D493/04 , C07D495/04 , C07D495/14 , C07D521/00 , C07J73/00
CPC classification number: C07D207/27 , C04B35/632 , C07C233/43 , C07C233/62 , C07C233/65 , C07C237/48 , C07C271/20 , C07C275/24 , C07C323/62 , C07C2601/02 , C07C2601/14 , C07C2602/08 , C07C2602/10 , C07D209/14 , C07D209/20 , C07D209/60 , C07D213/70 , C07D221/10 , C07D231/12 , C07D233/42 , C07D233/56 , C07D233/84 , C07D235/06 , C07D249/08 , C07D261/20 , C07D307/81 , C07D307/92 , C07D311/58 , C07D311/60 , C07D319/18 , C07D319/20 , C07D333/20 , C07D333/38 , C07D333/58 , C07D333/74 , C07D335/06 , C07D335/08 , C07D401/12 , C07D405/06 , C07D405/12 , C07D407/12 , C07D471/04 , C07D491/04 , C07D495/04 , C07D495/14
Abstract: The invention concerns compounds of formula (I): R-A-R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
Abstract translation: 本发明涉及式(I)化合物:R-A-R'其中:A如说明书中所定义; R表示基团(V),(VI),(VII)或(VIII),其中E,Q,R 1,R 2,R 3,v和R 4如 说明; R'表示 - (CH 2)t -R 5基团,其中t和R 5如说明书中所定义。
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公开(公告)号:US5464872A
公开(公告)日:1995-11-07
申请号:US375503
申请日:1995-01-18
Applicant: Michel Langlois , Pierre Renard , Gerard Adam
Inventor: Michel Langlois , Pierre Renard , Gerard Adam
IPC: C07D319/20 , A61K31/135 , A61K31/165 , A61K31/275 , A61K31/335 , A61K31/34 , A61K31/343 , A61K31/357 , A61K31/40 , A61K31/403 , A61K31/404 , A61P3/08 , A61P3/10 , A61P13/02 , A61P15/00 , A61P25/00 , A61P25/28 , A61P35/00 , A61P37/00 , A61P43/00 , C07C217/56 , C07C217/84 , C07C233/18 , C07C233/20 , C07C233/22 , C07C233/25 , C07C233/60 , C07C255/59 , C07D209/08 , C07D307/79 , C07D319/18 , A61K31/16 , C07C233/05
CPC classification number: C07D307/79 , C07C233/18 , C07C233/20 , C07C233/60 , C07D209/08 , C07D319/18 , C07C2101/02 , C07C2101/04 , C07C2101/08 , C07C2101/14 , C07C2102/10 , Y10S514/923
Abstract: A compound which is selected from those of formula (I): ##STR1## in which A, R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are as defined in the description, its optical isomers, and its addition salts thereof with a pharmaceutically-acceptable acid or base, and medicinal products containing the same which are useful for treating a disorder of the melatoninergic system.
Abstract translation: 选自式(I)的化合物:其中A,R 1,R 2,R 3,R 4,R 5和R 6如说明书中所定义,其光学异构体及其加成盐 与药学上可接受的酸或碱,以及含有它们的药物,其可用于治疗褪黑激素系统的病症。
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9.N-Aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones 失效
Title translation: N-芳基恶唑烷酮,恶唑烷硫醚,吡咯烷酮,吡咯烷和噻唑烷酮公开(公告)号:US4435415A
公开(公告)日:1984-03-06
申请号:US389136
申请日:1982-06-16
Applicant: Guy R. Bourgery , Colette A. Douzon , Jean-Francois R. Ancher , Alain P. Lacour , Patrick G. Guerret , Michel Langlois , Philippe L. Dostert
Inventor: Guy R. Bourgery , Colette A. Douzon , Jean-Francois R. Ancher , Alain P. Lacour , Patrick G. Guerret , Michel Langlois , Philippe L. Dostert
IPC: C07C41/03 , C07C41/26 , C07C43/178 , C07C309/73 , C07D207/08 , C07D207/26 , C07D207/277 , C07D263/16 , C07D263/20 , C07D263/24 , C07D277/14 , C07D277/24 , A61K31/42 , C07D263/14
CPC classification number: C07D207/08 , C07C309/73 , C07D207/26 , C07D207/277 , C07D263/16 , C07D263/20 , C07D263/24 , C07D277/14
Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
Abstract translation: 公开了N-芳基恶唑烷酮,恶唑烷硫醚,吡咯烷酮,吡咯烷和噻唑烷酮。 这些化合物具有抗抑郁活性。
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10.
公开(公告)号:US4413001A
公开(公告)日:1983-11-01
申请号:US388867
申请日:1982-06-16
Applicant: Guy R. Bourgery , Colette A. Douzon , Jean-Francois R. Ancher , Alain P. Lacour , Patrick G. Guerret , Michel Langlois , Philippe L. Dostert
Inventor: Guy R. Bourgery , Colette A. Douzon , Jean-Francois R. Ancher , Alain P. Lacour , Patrick G. Guerret , Michel Langlois , Philippe L. Dostert
IPC: C07C41/03 , C07C41/26 , C07C43/178 , C07C309/73 , C07D207/08 , C07D207/26 , C07D207/277 , C07D263/16 , C07D263/20 , C07D263/24 , C07D277/14 , C07D277/24 , A61K31/42 , A61K31/44 , C07D263/14 , C07D263/46
CPC classification number: C07D207/08 , C07C309/73 , C07D207/26 , C07D207/277 , C07D263/16 , C07D263/20 , C07D263/24 , C07D277/14
Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
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