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公开(公告)号:US20240299568A1
公开(公告)日:2024-09-12
申请号:US18261983
申请日:2022-01-19
发明人: Han XIAO , Xiang ZHANG
CPC分类号: A61K47/6803 , A61K47/64 , A61K47/6851 , A61P35/04
摘要: The present disclosure provides methods for treating bone diseases, such as bone cancers, bone metastasis of cancers, or osteoporosis, by administering a bone-targeting polypeptide conjugate. The bone-targeting polypeptide conjugate may be a bone-targeting antibody conjugate.
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公开(公告)号:US12073578B2
公开(公告)日:2024-08-27
申请号:US18307387
申请日:2023-04-26
发明人: Yicheng Wu , Vivek Boominathan , Huaijin Chen , Aswin C. Sankaranarayanan , Ashok Veeraraghavan
IPC分类号: G06T7/55 , H04N13/111 , H04N13/122 , H04N13/128 , H04N13/229
CPC分类号: G06T7/55 , H04N13/111 , H04N13/122 , H04N13/128 , H04N13/229 , G06T2200/08
摘要: A method for a passive single-viewpoint 3D imaging system comprises capturing an image from a camera having one or more phase masks. The method further includes using a reconstruction algorithm, for estimation of a 3D or depth image.
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公开(公告)号:US20240189458A1
公开(公告)日:2024-06-13
申请号:US18570949
申请日:2022-06-15
发明人: Jeffrey TABOR , Omid VEISEH , Robert BRITTON , Moshe BARUCH , Annie GOODWIN , Elena MUSTEATA , Michael DOERFERT , Samira AGHLARA-FOTOVAT , Maxwell HUNT
CPC分类号: A61K49/0008 , A61K9/4808 , A61K9/5015 , A61K9/5036 , A61K9/5094 , A61K9/5115 , A61K35/74 , A61K49/0091 , C12N11/04 , C12N11/10
摘要: The present disclosure provides compositions comprising encapsulated engineered bacteria. The bacteria may be engineered to act as sensors of biomarkers, such as inflammation, as well as to produce diagnostic or therapeutic agents.
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公开(公告)号:US11958043B2
公开(公告)日:2024-04-16
申请号:US16612660
申请日:2018-05-11
发明人: Nancy Jean Halas , Peter Nordlander , Hossein Robatjazi , Dayne Francis Swearer , Chao Zhang , Hangqi Zhao , Linan Zhou
IPC分类号: B01J35/00 , B01J19/12 , B01J21/02 , B01J21/04 , B01J21/10 , B01J23/00 , B01J23/38 , B01J23/44 , B01J23/50 , B01J23/52 , B01J23/58 , B01J23/72 , B01J23/78 , B01J23/89 , B01J27/04 , B01J27/14 , B01J27/20 , B01J27/22 , B01J27/24 , B01J31/06 , B01J35/02 , B01J35/10 , B01J37/02 , B01J37/03 , B01J37/08 , B01J37/34 , C01B3/04 , C01B3/40 , C01B4/00 , C01B5/00 , C01B21/02 , C01B32/40 , B01J31/16
CPC分类号: B01J35/004 , B01J19/123 , B01J19/127 , B01J21/02 , B01J21/04 , B01J21/10 , B01J23/002 , B01J23/38 , B01J23/44 , B01J23/50 , B01J23/52 , B01J23/58 , B01J23/72 , B01J23/78 , B01J23/8926 , B01J23/8946 , B01J27/04 , B01J27/14 , B01J27/20 , B01J27/22 , B01J27/24 , B01J31/06 , B01J35/0006 , B01J35/0013 , B01J35/002 , B01J35/0033 , B01J35/006 , B01J35/008 , B01J35/026 , B01J35/1066 , B01J37/0203 , B01J37/0225 , B01J37/03 , B01J37/031 , B01J37/035 , B01J37/08 , B01J37/344 , C01B3/047 , C01B3/40 , C01B4/00 , C01B5/00 , C01B21/02 , C01B32/40 , B01J31/1691 , B01J2219/00635 , B01J2523/00 , B01J2540/66 , C01B2203/0238 , C01B2203/1076 , C01B2203/1082 , C01B2203/1241 , B01J2523/00 , B01J2523/17 , B01J2523/22 , B01J2523/31 , B01J2523/821
摘要: A method of making a multicomponent photocatalyst, includes inducing precipitation from a pre-cursor solution comprising a pre-cursor of a plasmonic material and a pre-cursor of a reactive component to form co-precipitated particles; collecting the co-precipitated particles; and annealing the co-precipitated particles to form the multicomponent photocatalyst comprising a reactive component optically, thermally, or electronically coupled to a plasmonic material.
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公开(公告)号:US11922313B2
公开(公告)日:2024-03-05
申请号:US16077395
申请日:2017-02-06
摘要: A system may include a processor and a memory. The memory may include program code that provides operations when executed by the processor. The operations may include: partitioning, based at least on a resource constraint of a platform, a global machine learning model into a plurality of local machine learning models; transforming training data to at least conform to the resource constraint of the platform; and training the global machine learning model by at least processing, at the platform, the transformed training data with a first of the plurality of local machine learning models.
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公开(公告)号:US20240045655A1
公开(公告)日:2024-02-08
申请号:US17761116
申请日:2022-03-11
发明人: Kaiyuan Yang , Zhiyu Chen
IPC分类号: G06F7/544 , G11C11/412 , G11C11/419
CPC分类号: G06F7/5443 , G11C11/412 , G11C11/419
摘要: A charge-domain IMC circuit is disclosed and includes: a cluster of 6T SRAM cells; a charge- domain MAC circuit; and an LBL connected to a bit-line of each of the 6T SRAM cells. The MAC circuit includes: a MOS transistor; an input switch; an output switch; an input port; an output port; and a capacitor. The LBL is connected to a gate of the MOS transistor. A first terminal of the MOS transistor is connected to a DC voltage, and a second terminal of the MOS transistor is connected to the output port via the output switch. The second terminal of the MOS transistor is connected to the input port via the input switch and to a first side of the capacitor. A second side of the capacitor is grounded. Other variants of the IMC circuit are disclosed, some of which having a ciSAR ADC or a TD-ADC.
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公开(公告)号:US20240041755A1
公开(公告)日:2024-02-08
申请号:US18258550
申请日:2021-12-17
发明人: Omid VEISEH , Amanda NASH , Boram KIM , Damon BERMAN , Lauren CHENG , David ZHANG
CPC分类号: A61K9/0024 , A61K47/36 , A61K9/5036 , A61K35/12 , C07K14/52 , A61K39/0011
摘要: The present disclosure relates to implantable constructs and related compositions comprising a plurality of cells producing antigens and/or immune effector molecules.
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公开(公告)号:US20230384297A1
公开(公告)日:2023-11-30
申请号:US18173246
申请日:2023-02-23
发明人: Peter B. LILLEHOJ , Jiran LI
IPC分类号: G01N33/543 , G01N33/58 , B01L3/00
CPC分类号: G01N33/54326 , G01N33/58 , B01L3/502761 , B01L2400/043
摘要: A simple immunosensor for rapid and high sensitivity measurements of protein biomarkers, such as SARS-CoV-2 nucleocapsid protein, in serum. The assay is based on a unique sensing scheme utilizing dually labeled magnetic nanobeads for immunomagnetic enrichment and signal amplification. This immunosensor can be integrated onto a microfluidic chip, which offers the advantages of minimal sample and reagent consumption, simplified sample handling, and enhanced detection sensitivity.
An ultrafast magneto-immunosensor, which employs AC electrothermally driven flow (ACEF) for accelerated mass transport and enhanced immunocomplex formation, is developed for high sensitivity protein measurement in whole blood samples.-
公开(公告)号:US20230357885A1
公开(公告)日:2023-11-09
申请号:US18246451
申请日:2021-09-24
发明人: James M. Tour , Bing Deng
CPC分类号: C22B7/001 , C22B1/245 , C22B7/007 , C22B11/046 , C22B11/025
摘要: Ultrafast flash Joule heating synthesis methods and systems, and more particularly, ultrafast synthesis methods to recover precious metals recovery and other metals from electronic waste (e-waste).
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公开(公告)号:US20230348542A1
公开(公告)日:2023-11-02
申请号:US18310512
申请日:2023-05-01
发明人: Jiaozhi LU , Zongru LI , Qionghua SHEN
IPC分类号: C07K14/195 , B82Y5/00 , A61P37/02
CPC分类号: C07K14/195 , B82Y5/00 , A61P37/02
摘要: In one aspect, the present disclosure describes ultrasmall gas vesicle compositions comprising modified gas vesicle shell proteins. Also disclosed herein are polynucleotide sequences which encode such compositions. Methods of treatment comprising administering such gas vesicle compositions are also provided.
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