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公开(公告)号：US20170052384A1
公开(公告)日：2017-02-23
申请号：US15307759
申请日：2014-04-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Charles M Santori , Alexander Govyadinov
CPC classification number: G02B27/425 , G01N21/05 , G02B6/003 , G02B6/0035 , G02B21/00 , G02B21/0004 , G02B21/06 , G02B21/362 , G03H1/0244 , G03H1/041 , G03H1/0443 , G03H1/0465 , G03H1/0866 , G03H1/265 , G03H2001/0033 , G03H2001/0447 , G03H2001/0452 , G03H2001/0469 , G03H2001/0471 , G03H2001/0473 , G03H2001/2226 , G03H2222/34 , G03H2223/16 , G03H2223/19 , G03H2223/23 , G03H2227/02 , G03H2227/03 , G03H2240/56 , H04N5/2256
Abstract: Imaging apparatus and methods using diffraction-based illumination are disclosed. An example apparatus includes a diffraction grating to redirect light from a light source toward a sample to thereby illuminate the sample. The example apparatus also includes an image sensor to detect a diffraction pattern created by the illuminated sample.
Abstract translation: 公开了使用衍射照明的成像设备和方法。 示例性装置包括衍射光栅，用于将来自光源的光朝向样品重新定向，从而照射样品。 示例性装置还包括用于检测由照射样品产生的衍射图案的图像传感器。
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112.发明授权公开(公告)号：US09492999B2
公开(公告)日：2016-11-15
申请号：US14588821
申请日：2015-01-02
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Kenneth Ward , Alexander Govyadinov
CPC classification number: B41J2/04581 , B41J2/0451 , B41J2/0456 , B41J2/04561 , B41J2/0458 , B41J2/2142 , G01N35/1016 , G01N2035/1034
Abstract: Drop detection are disclosed. An example liquid dispensing device includes a controller to control dispensing of a first drop from a first orifice and a second drop from a second orifice, a sensor to monitor the first orifice to detect at least one of a presence or an absence of a drop from the first orifice and, in response to the sensor detecting an absence of the first drop, the controller is to classify the first orifice as at least one of occluded or non-functioning.
Abstract translation: 公开了跌落检测。 示例性液体分配装置包括控制器，用于控制从第一孔口分出第一液滴和从第二孔口分出第二液滴;传感器，用于监测第一孔口，以检测滴液的存在或不存在 所述第一孔口，并且响应于所述传感器检测到不存在所述第一液滴，所述控制器将所述第一孔口分类为闭塞或不起作用的至少一个。
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公开(公告)号：US09457584B2
公开(公告)日：2016-10-04
申请号：US14958022
申请日：2015-12-03
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Alexander Govyadinov , Craig Olbrich , Brian M. Taff
CPC classification number: B41J2/17596 , B41J2/1404 , B41J2/14145 , B41J2/1433 , B41J2/15 , B41J2/175 , B41J2002/14387 , B41J2002/14467 , B41J2202/12
Abstract: In an embodiment, a fluid ejection device includes a die substrate having first and second fluid slots along opposite substrate sides and separated by a substrate central region. First and second internal columns of closed chambers are associated with the first and second slots, respectively, and the internal columns are separated by the central region. Fluidic channels extending across the central region fluidically couple closed chambers from the first internal column with closed chambers from the second internal column. Pump actuators in each closed chamber pump fluid through the channels from slot to slot.
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公开(公告)号：US20160228873A1
公开(公告)日：2016-08-11
申请号：US15134300
申请日：2016-04-20
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Alexander Govyadinov , Pavel Kornilovich , Erik D. Torniainen , David P. Markel
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01F5/0275 , B01F5/10 , B01F13/0059 , B01L3/50273 , B01L3/502738 , B01L3/502769 , B01L2200/0636 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/088 , B01L2400/0406 , B01L2400/0415 , B01L2400/043 , B01L2400/0433 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0633 , F01D1/00 , F01D3/00
Abstract: A microfluidic mixing device comprises a main channel and a number of secondary channels extending from a portion of the main channel and entering another portion of the main channel. A number of actuators are located in the secondary channels to pump fluids through the secondary channels. A microfluidic mixing system comprises a microfluidic mixing device. The microfluidic mixing device comprises a main fluid mixing channel, a number of main channel actuators to pump fluid through the main fluid mixing channel, a number of secondary channels fluidly coupled to the main fluid mixing channel, and a number of secondary channel actuators to pump fluids through the secondary channels. The microfluidic mixing device also comprises a fluid source, and a control device to provide fluids from the fluid source to the microfluidic mixing device and activate the main channel actuators and secondary channel actuators.
Abstract translation: 微流体混合装置包括主通道和从主通道的一部分延伸并进入主通道的另一部分的多个次通道。 多个致动器位于次级通道中以将流体泵送通过次级通道。 微流体混合系统包括微流体混合装置。 微流体混合装置包括主流体混合通道，多个主通道致动器以泵送通过主流体混合通道的流体，流体耦合到主流体混合通道的多个次通道，以及多个辅助通道致动器以泵送 流体通过次级通道。 微流体混合装置还包括流体源和控制装置，以将流体从流体源提供给微流体混合装置并且激活主通道致动器和次通道致动器。
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公开(公告)号：US20140098156A1
公开(公告)日：2014-04-10
申请号：US14123194
申请日：2011-05-31
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Brian M. Taff , Alexander Govyadinov
CPC classification number: G01N21/64 , B41J2/04561 , B41J2/04586 , B41J2/125
Abstract: A drop detection method comprises ejecting an ink drop that includes a fluorescent agent, illuminating the ink drop in flight with excitation light to excite the fluorescent agent, detecting fluorescence emitted by the drop in flight, having a longer wavelength than a wavelength of the excitation light, and, prior to such detecting, filtering out light having a shorter wavelength than the fluorescence wavelength; and a printer with drop detection assembly for performing the method.
Abstract translation: 液滴检测方法包括喷射包含荧光剂的墨滴，用激发光照射飞行中的墨滴以激发荧光剂，检测由飞行中滴下的荧光，具有比激发光的波长更长的波长 并且在这种检测之前，过滤出具有比荧光波长短的波长的光; 以及具有用于执行该方法的液滴检测组件的打印机。
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Patent Agency Ranking
公开(公告)号：US12025549B2
公开(公告)日：2024-07-02
申请号：US17414155
申请日：2019-05-13
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Alexander Govyadinov , Diane R. Hammerstad
IPC: G01N15/12 , B01L3/00 , B81B7/02 , G01N15/10 , G01N15/1031 , G01N33/543
CPC classification number: G01N15/12 , B01L3/502761 , B81B7/02 , G01N15/1023 , G01N15/1031 , G01N33/54386 , B01L2200/025 , B01L2200/0652 , B01L2200/0663 , B01L2300/0645 , B01L2300/0663 , B01L2300/0829 , B01L2300/14 , B01L2400/02 , B01L2400/0487 , G01N2015/1006 , G01N2015/1028
Abstract: A system includes a microchannel analysis region, a first fluid actuation device, a second fluid actuation device, a sensor, and a controller. The first fluid actuation device is at a first end of the microchannel analysis region. The second fluid actuation device is at a second end of the microchannel analysis region opposite to the first end. The sensor is within the microchannel analysis region between the first fluid actuation device and the second fluid actuation device. The sensor measures an impedance of a fluid within the microchannel analysis region. The controller activates the first fluid actuation device to generate a first pressure wave in the fluid and activates the second fluid actuation device to generate a second pressure wave in the fluid. The first pressure wave and the second pressure wave converge at the sensor.
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公开(公告)号：US20240207857A1
公开(公告)日：2024-06-27
申请号：US18557285
申请日：2021-04-29
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Viktor Shkolnikov , Alexander Govyadinov
CPC classification number: B01L7/52 , B01L3/0241 , B01L2200/0673 , B01L2200/16 , B01L2300/1805 , B01L2400/0487
Abstract: A droplet PCR system is described herein. The droplet PCR system comprises a chamber having a heating surface, a droplet dispenser to dispense PCR-reagent-containing droplets into the chamber, a heater disposed onto the heating surface of the chamber to heat a layer of fluid adjacent the heating surface, and a controller to control the heater to produce a pulsed heat flux.
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公开(公告)号：US20240123446A1
公开(公告)日：2024-04-18
申请号：US18202845
申请日：2023-05-26
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Alexander Govyadinov , Viktor Shkolnikov
IPC: B01L3/00
CPC classification number: B01L3/502761 , B01L2200/025 , B01L2300/0829
Abstract: A microfluidic system may comprise a dispense head with multiple dispensers, each dispensing a different cell type, such as single pairs of individual target cells and individual sensor cells. Interaction between the cells may be observed based on, for example, fluorescence. Individual target cells may then be selected, based on observations, for use or for further investigation. As an example, target cells may be B-cells, and enhanced selection of B-cells aids more direct antibody discovery.
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公开(公告)号：US20230381779A1
公开(公告)日：2023-11-30
申请号：US18032710
申请日：2020-10-20
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor： Alexander Govyadinov , Viktor Shkolnikov
CPC classification number: B01L3/502761 , G01N35/0098 , B01L3/0268 , B01L2300/1827 , B01L2400/043 , B01L2400/0442 , G01N2035/00237
Abstract: A method comprising receiving, at a microfluidic channel, a biologic sample including a cell and providing a magnetic field within the microfluidic channel using a first magnet, wherein the magnetic field attracts a first plurality of magnetic particles disposed within the microfluidic channel. The method further includes activating a first resistor disposed within the microfluidic channel to agitate a volume of fluid within the microfluidic channel, and in response, moving the first plurality of magnetic particles through the microfluidic channel to lyse the cell and to release cellular material from the cell.
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公开(公告)号：US20230372938A1
公开(公告)日：2023-11-23
申请号：US18030489
申请日：2021-09-14
Applicant: Hewlett-Packard Development Company, L.P.
Inventor： Pavel Kornilovich , Alexander Govyadinov
IPC: B01L3/00
CPC classification number: B01L3/502784 , B01L3/50273 , B01L2200/0673 , B01L2300/0816 , B01L2400/0442 , B01L2400/0688 , B01L2400/084 , B01L2200/0689
Abstract: In one example in accordance with the present disclosure, a fluid analysis system is described. The fluid analysis system includes an inlet channel to an analysis chamber. The analysis chamber is to receive a fluid sample to be analyzed. The fluid analysis system also includes a fluid branch having a fluidic junction along the inlet channel and a gas chamber to house a volume of trapped gas, the gas chamber being in fluid communication with the fluid branch. The fluid analysis system also includes a sealing fluid delivery system to fill the fluid branch with a sealing fluid and a heater adjacent the gas chamber to heat the gas chamber such that the trapped gas expands to push the sealing fluid into the inlet channel to seal the analysis chamber.
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