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    Microfabricated system for magnetic field generation and focusing
    12.
    发明授权
    Microfabricated system for magnetic field generation and focusing 有权
    用于磁场产生和聚焦的微型系统

    公开(公告)号：US07791440B2

    公开(公告)日：2010-09-07

    申请号：US10988266

    申请日：2004-11-12

    Applicant: Qasem Ramadan ,  Victor Samper ,  Daniel Puiu Poenar ,  Chen Yu

    Inventor： Qasem Ramadan ,  Victor Samper ,  Daniel Puiu Poenar ,  Chen Yu

    IPC: H01F3/00 ,  H01F5/00

    CPC classification number: H01F5/003 ,  H01F41/046 ,  H01F2007/062 ,  H01F2007/068 ,  H01F2017/0086 ,  H01H50/005 ,  H01L23/5227 ,  H01L23/645 ,  H01L2924/0002 ,  H01L2924/3011 ,  H01L2924/00

    Abstract: A method of forming, in or on a Si substrate, planar micro-coils with coil windings of high aspect ratio (>3) and a wide variety of geometric shapes. The micro-coils may be formed on a Si substrate and be embedded in a dielectric, or they may be formed in trenches within a Si substrate. The micro-coils may have field enhancing ferromagnetic pillars rising above the micro-coil plane, formed at positions of maximum magnetic field strength and the micro-coils may also include magnetic layers formed beneath the substrate and contacting the pillars to form a substantially closed pathway for the magnetic flux. The substrate may be thinned to membrane proportions. These micro-coils produce strong magnetic fields with strong field gradients and can be used in a wide variety of processes that involve the exertion of strong magnetic forces at small distances or the creation of magnetic wells for trapping and manipulating small particles.

    Abstract translation: 在Si衬底中或其上形成具有高纵横比（> 3）的线圈绕组和各种几何形状的平面微型线圈的方法。 微型线圈可以形成在Si衬底上并嵌入电介质中，或者它们可以形成在Si衬底内的沟槽中。 微型线圈可以具有在微型线圈平面上方上升的场强增强的铁磁柱，形成在最大磁场强度的位置，并且微型线圈还可以包括形成在衬底下方的磁性层，并与柱体接触以形成基本封闭的通路 用于磁通量。 衬底可以被薄化成膜的比例。 这些微型线圈产生具有强场梯度的强磁场，并且可以用于涉及在较小距离处施加强磁力或产生用于捕获和操纵小颗粒的磁井的各种工艺。

    Rotation-based microsampler, system and method of using the same
    15.
    发明申请
    Rotation-based microsampler, system and method of using the same 审中-公开
    基于旋转的微量采样器，使用它的系统和方法

    公开(公告)号：US20070224591A1

    公开(公告)日：2007-09-27

    申请号：US11389586

    申请日：2006-03-27

    Applicant: John Gui ,  Wei-Cheng Tian ,  Atanu Phukan ,  Shashi Thutupalli ,  Victor Samper

    Inventor： John Gui ,  Wei-Cheng Tian ,  Atanu Phukan ,  Shashi Thutupalli ,  Victor Samper

    IPC: C12Q1/00 ,  C12M3/00

    CPC classification number: B01L3/502746 ,  B01L3/502753 ,  B01L2300/0654 ,  B01L2300/0681 ,  B01L2300/0803 ,  B01L2300/0864 ,  B01L2400/0409 ,  B01L2400/086 ,  G01N15/042 ,  G01N35/00029 ,  G01N2015/045

    Abstract: A microsampler disc for use in the analysis of agents is described as including a plurality of microstructures configured and spaced to promote movement of a fluidic medium containing agents radially outwardly and promote filtering of one species of agents from other species of agents. An analysis system using the microsampler disc is also described. A method for separating one species of agent from one or more other species of agents is described as including introducing a fluidic medium containing at least one species of agents to a microsampler disc having a plurality of microstructures, rotating the microsampler disc to promote movement of the fluidic medium outwardly, collecting the at least one species of agent in a specific set of detection zones, and analyzing the at least one species of agent.

    Abstract translation: 用于分析试剂的微量进样器盘被描述为包括构造和间隔开的多个微结构，以促进包含试剂径向向外的流体介质的运动，并促进一种试剂从其它物种的过滤。 还描述了使用微量进样器盘的分析系统。 描述了将一种试剂与一种或多种其它物种分离的方法，包括将含有至少一种试剂的流体介质引入具有多个微结构的微量进样器盘，旋转微量进样器盘以促进 流体介质向外收集特定组检测区域中的至少一种试剂，并分析至少一种试剂。

    Method of forming branched structures
    16.
    发明申请
    Method of forming branched structures 审中-公开
    形成支化结构的方法

    公开(公告)号：US20060131265A1

    公开(公告)日：2006-06-22

    申请号：US11015116

    申请日：2004-12-17

    Applicant: Victor Samper ,  Dong-Kee Yi ,  Tanu Kustandi

    Inventor： Victor Samper ,  Dong-Kee Yi ,  Tanu Kustandi

    IPC: C23F1/00 ,  B44C1/22 ,  C03C25/68

    CPC classification number: B81C99/0095 ,  H01L21/0337 ,  H01L21/3086

    Abstract: The present invention provides a method of forming a branched structure which comprises applying colloidal-sized particles over structures. The coated structures are then etched such that the structures are etched through the colloidal particles to form branched structures. The etch may be a reactive ion etch. The structures may be microstructures formed as high aspect ratio microstructures. The colloidal-sized particles may be applied as a colloidal solution and a polyelectrolyte (PE) layer may be applied to the microstructures prior to the colloidal solution to promote adsorption of the colloidal particles.

    Abstract translation: 本发明提供一种形成支化结构的方法，其包括在结构上施加胶体尺寸的颗粒。 然后蚀刻涂覆的结构，使得结构被蚀刻通过胶体颗粒以形成分支结构。 蚀刻可以是反应离子蚀刻。 该结构可以是高纵横比微结构形成的微结构。 可以将胶体尺寸的颗粒作为胶体溶液施用，并且可以在胶体溶液之前将微电极施加到微结构上以促进胶体颗粒的吸附。

    Micromixer apparatus and methods of using same
    17.
    发明申请
    Micromixer apparatus and methods of using same 审中-公开
    微混合器装置及其使用方法

    公开(公告)号：US20060087918A1

    公开(公告)日：2006-04-27

    申请号：US11301386

    申请日：2005-12-13

    Applicant: Hongmiao Ji ,  Victor Samper

    Inventor： Hongmiao Ji ,  Victor Samper

    IPC: B01F5/00 ,  B81B1/00

    CPC classification number: B01F13/0059 ,  B01F5/0646 ,  B01F5/0647 ,  B01F2215/0431 ,  B01F2215/0495 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00819 ,  B01J2219/00835 ,  B01J2219/00889 ,  B01J2219/00952 ,  B01J2219/00984 ,  B01J2219/00995 ,  B01L3/5027 ,  Y10S366/03

    Abstract: Microfluidics mixing apparatus and methods of using same are disclosed for mixing fluids using increasing centrifugal force as the fluids being mixed traverse a mixing channel. One inventive apparatus comprises a generally planar substrate having a top major surface and a bottom major surface generally parallel to the top major surface, and a cover plate over the top major surface. The substrate has at least one inlet port that routes fluid to the top major surface, and at least one outlet port for mixed fluid. The substrate comprises a mixing channel having a depth measured from the top surface and a width, the mixing channel adapted to route fluids to be mixed therein in laminar flow and in a substantially spiral flow pattern that is parallel to the top surface. Apparatus of the invention can mix fluids flowing serially, or two or more fluids entering the device from different feed channels.

    Abstract translation: 公开了微流体混合装置及其使用方法，用于当混合的流体穿过混合通道时，使用增加的离心力混合流体。 一种本发明的装置包括具有大体上平行于顶部主表面的顶部主表面和底部主表面的大致平面的基底，以及在顶部主表面上的盖板。 衬底具有至少一个将流体输送到顶部主表面的入口端口和用于混合流体的至少一个出口端口。 衬底包括具有从顶表面测量的深度和宽度的混合通道，混合通道适于在层流中引导待混合的流体并且以与顶表面平行的基本上螺旋形的流动图案。 本发明的装置可以混合串联流动的流体，或混合从不同进料通道进入装置的两种或更多种流体。

    Microvalve
    18.
    发明授权
    Microvalve 有权
    微型阀门

    公开(公告)号：US08753587B2

    公开(公告)日：2014-06-17

    申请号：US13514132

    申请日：2010-12-30

    Applicant: Victor Samper ,  Christian Rensch ,  Christoph Boeld ,  Marko Baller

    Inventor： Victor Samper ,  Christian Rensch ,  Christoph Boeld ,  Marko Baller

    IPC: B01D21/00

    CPC classification number: F16K99/0001 ,  F16K99/0015 ,  F16K2099/008

    Abstract: A microvalve assembly (10) includes an elongate valve body (14) having opposed first and second major surfaces, the first major surface defining a valve recess (34) and the second major surface defining first and second fluid ports (20,22). Both the fluid input port and the fluid output port extend in fluid communication with the valve recess. A gasket (12) is freely positioned within the valve recess so as to extend in overlying registry with either or both of fluid ports. A valve cover (16) is bonded to the valve body and includes a first planar surface positioned in overlying registry with the valve recess so as to enclose the gasket therein. The valve cover is deflectable into the valve recess so as to cause the gasket to seal at least one of the fluid ports.

    Abstract translation: 微阀组件（10）包括具有相对的第一和第二主表面的细长阀体（14），所述第一主表面限定阀凹部（34），所述第二主表面限定第一和第二流体端口（20,22）。 流体输入端口和流体输出端口都与阀门凹口流体连通地延伸。 垫片（12）自由地定位在阀凹部内，以便在任一个或两个流体端口的上面对准中延伸。 阀盖（16）与阀体结合并且包括位于与阀凹部对齐的第一平坦表面，以便将垫圈包围在其中。 阀盖可偏转到阀门凹口中，以便使垫圈密封至少一个流体端口。

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