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69 条记录 (耗时 0.035 秒)

    Extraction and transportation of blood for analysis
    13.
    发明授权
    Extraction and transportation of blood for analysis 有权
    提取和运输血液进行分析

    公开(公告)号：US06364890B1

    公开(公告)日：2002-04-02

    申请号：US09614318

    申请日：2000-07-12

    申请人： Paul Lum ,  Leslie A. Leonard ,  Edward D. Verdonk ,  Dominique M. Freeman ,  Michael Greenstein ,  Catherine Keely-Templin

    发明人： Paul Lum ,  Leslie A. Leonard ,  Edward D. Verdonk ,  Dominique M. Freeman ,  Michael Greenstein ,  Catherine Keely-Templin

    IPC分类号： A61B1732

    CPC分类号： A61B5/15144 ,  A61B5/14532 ,  A61B5/150022 ,  A61B5/150099 ,  A61B5/150106 ,  A61B5/150427 ,  A61B5/150969 ,  A61B5/150984 ,  A61B5/15113

    摘要： A device for sampling blood from the skin of a patient by puncture. The device includes one or more lancets for lancing the skin and a fluid-conducting plate unit for transporting blood from the lancing wound. The plate unit has one or more channels for conducting fluid to one or more target locations. Preferably there is a first channel for conducting away a first portion of fluid that contains more of a fluid that is emitted initially (initial fluid) from the puncture wound and a second channel for conducting a second portion of fluid that contains less of the initial fluid from the puncture wound. Blood is drawn into the channels by capillary force. The device can be used to lance the skin and obtain a representative sample of blood with relatively simple procedures.

    摘要翻译： 一种用于通过穿刺从患者皮肤取样血液的装置。 该装置包括用于切割皮肤的一个或多个刺血针和用于从穿刺伤口输送血液的导流板单元。 板单元具有用于将流体传导到一个或多个目标位置的一个或多个通道。 优选地，存在用于传导第一部分流体的第一通道，所述第一部分流体包含更多的来自穿刺伤口的最初发射的流体（初始流体）和用于传导含有较少初始流体的第二部分流体的第二通道 从穿刺伤口。 通过毛细血管力将血液吸入通道。 该装置可用于以相对简单的程序来刺激皮肤并获得代表性的血液样品。

    Electrically anisotropic elastomeric structure with mechanical compliance and scrub
    16.
    发明授权
    Electrically anisotropic elastomeric structure with mechanical compliance and scrub 失效
    电子各向异性弹性体结构，具有机械顺应性和磨擦

    公开(公告)号：US5529504A

    公开(公告)日：1996-06-25

    申请号：US424776

    申请日：1995-04-18

    申请人： Michael Greenstein ,  Masakuzu Sugimoto ,  Hiroshi Yada

    发明人： Michael Greenstein ,  Masakuzu Sugimoto ,  Hiroshi Yada

    IPC分类号： G01R1/073 ,  H01L23/32 ,  H01R12/51 ,  H01R13/24 ,  H05K3/36 ,  H05K1/14 ,  H01R9/09 ,  H05K3/10

    CPC分类号： H01R13/2414 ,  G01R1/0735 ,  H01L23/32 ,  H01R12/73 ,  H01L2924/0002 ,  H01R12/52 ,  H01R12/714 ,  Y10T29/49128 ,  Y10T29/49204 ,  Y10T29/49213

    摘要： A microconnection device and a method of forming such a device include providing an array of electrically interconnected conductors within through holes of an insulative flexible film. Preferably, each conductor has a microbump. Since the conductors are interconnected, the microbumps define a cluster for contact with a single contact, such as an input/output pad of a semiconductor device. In the preferred embodiment, the flexible film includes a cavity at the central region of the cluster, thereby enhancing the flexibility of the film. By applying a load force within the central region of the cluster, the flexible film is caused to bend in a manner to achieve load compliance and a lateral scrub for removing contaminants, oxides and the like at the interface of the microbumps and the contact. A top bump that is misaligned with the microbumps may be formed to ensure proper localization of the load force within the central region. Preferably, the flexible film includes an array of microconnection devices.

    摘要翻译： 微型连接装置和形成这种装置的方法包括在绝缘柔性膜的通孔内提供电互连导体的阵列。 优选地，每个导体具有微型凹槽。 由于导体互连，微胶片限定了与单个接触件（例如半导体器件的输入/输出焊盘）接触的簇。 在优选实施例中，柔性膜在簇的中心区域包括空腔，由此提高膜的柔性。 通过在簇的中心区域内施加负载力，使得柔性膜以使微量营养物和接触物的界面处的污染物，氧化物等去除污染物，氧化物等的负载顺应性和侧向洗涤的方式弯曲。 可以形成与微胶条不对准的顶部凸起，以确保负载力在中心区域内的适当定位。 优选地，柔性膜包括微连接装置的阵列。

    Biologically pure culture of the microorganism, streptomyces cyaneogriseus subspecies noncyanogenus, or a mutant thereof
    17.
    发明授权
    Biologically pure culture of the microorganism, streptomyces cyaneogriseus subspecies noncyanogenus, or a mutant thereof 失效
    微生物的生物学纯培养物，非花青素链霉菌亚种，或其突变体

    公开(公告)号：US5418168A

    公开(公告)日：1995-05-23

    申请号：US927581

    申请日：1992-08-10

    申请人： Guy T. Carter ,  Margaret J. Torrey ,  Michael Greenstein

    发明人： Guy T. Carter ,  Margaret J. Torrey ,  Michael Greenstein

    IPC分类号： A01N63/02 ,  C07H19/01 ,  C12P1/06 ,  C12N1/20 ,  C12P17/18

    CPC分类号： C07H19/01 ,  A01N63/02 ,  C12P1/06 ,  Y10S435/88 ,  Y10S435/886

    摘要： This invention relates to new agents designated LL-F28249.alpha., LL-F28249.beta., LL-F28249.gamma., LL-F28249.delta., LL-F28249.epsilon., LL-F28249.zeta., LL-F28249.eta., LL-F28249.theta., LL-F28249.iota., LL-F28249.kappa., LL-F28249.lambda., LL-F28249.mu., LL-F28249.nu., and LL-F28249.omega., to their production by fermentation, to methods for their recovery and concentration from crude solutions, to processes for their purification and to pharmaceutically and pharmacologically-acceptable salts thereof. The present invention includes within its scope the biologically pure culture which produces there agents, derived from a newly-discovered and previously uncultured microorganism, Streptomyces cyaneogriseus subsp. noncyanogenus, NRRL 15773.

    摘要翻译： 本发明涉及称为LL-F28249α，LL-F28249β，LL-F28249γ，LL-F28249Δ，LL-F28249ε，LL-F28249zeta，LL-F28249 eta，LL-F28249θ，LL-F28249 iota，LL-F28249 kappa，LL-F28249λ，LL-F28249 mu，LL-F28249nu和LL-F28249 omega，通过发酵生产，其从粗溶液中回收和浓缩的方法，以及其纯化方法 以及其药学上和药理上可接受的盐。 本发明在其范围内包括衍生自新发现和先前未培养的微生物Streptomyces cyaneogriseus subsp。的生物纯培养物。 非花青素，NRRL 15773。