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    Method, system and device for providing customized point of care testing
    41.
    发明申请
    Method, system and device for providing customized point of care testing 审中-公开
    方法，系统和设备，提供定制的护理点测试

    公开(公告)号：US20140320807A1

    公开(公告)日：2014-10-30

    申请号：US13874470

    申请日：2013-04-30

    申请人： Shyam Thangaraju ,  Siva Sakthivel Sadasivam

    发明人： Shyam Thangaraju ,  Siva Sakthivel Sadasivam

    IPC分类号： A61B5/00 ,  A61B3/14 ,  A61B5/145 ,  A61B10/00 ,  A61B5/024 ,  A61B5/053

    CPC分类号： A61B5/7435 ,  A61B3/14 ,  A61B5/02007 ,  A61B5/02125 ,  A61B5/024 ,  A61B5/0531 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/4041 ,  A61B10/0051 ,  A61B10/007 ,  A61B2560/0468 ,  A61B2562/0295

    摘要： A method, system and device for providing Point of Care Testing (POCT) are disclosed. The POCT comprises of a device that enables the patient to self conduct plurality of diagnostic tests for a chronic disease such as diabetes mellitus. The method is modular and enables the user to select set of tests from comprehensive list of diagnostic tests. The device provides a strip port to enable testing of various biochemical parameters. Also, the device comprises an ophthalmoscope with a built-in camera to capture images of the retina, a set of piezoelectric sensors for measuring pulse wave velocity (PWV), a pair of electrodes for measuring skin impedance. The method enables the device to log on the test data for future use and analysis. The device can be used for frequent monitoring of health parameters of a user suffering from diabetes mellitus.

    摘要翻译： 公开了一种提供护理测试点（POCT）的方法，系统和装置。 POCT包括使得患者能够对慢性疾病如糖尿病进行多次诊断测试的装置。 该方法是模块化的，使用户能够从综合诊断测试列表中选择一组测试。 该设备提供条形端口，以便能够测试各种生物化学参数。 此外，该装置还包括具有内置照相机的检眼镜以捕获视网膜的图像，一组用于测量脉搏波速度（PWV）的压电传感器，用于测量皮肤阻抗的一对电极。 该方法使设备能够登录测试数据以备将来使用和分析。 该装置可用于频繁监测患有糖尿病的患者的健康参数。

    MEASUREMENT OF NEURAL FUNCTIONALITY USING PHASE SENSITIVE OPTICAL COHERENCE REFLECTOMETRY
    42.
    发明申请
    MEASUREMENT OF NEURAL FUNCTIONALITY USING PHASE SENSITIVE OPTICAL COHERENCE REFLECTOMETRY 有权
    使用相敏感光学相干反射测量法测量神经功能

    公开(公告)号：US20140171807A1

    公开(公告)日：2014-06-19

    申请号：US13720563

    申请日：2012-12-19

    申请人： Taner Akkin ,  Thomas E. Milner ,  Digant P. Dave ,  H. Grady Rylander, III

    发明人： Taner Akkin ,  Thomas E. Milner ,  Digant P. Dave ,  H. Grady Rylander, III

    IPC分类号： A61B5/00 ,  A61N1/00 ,  A61N5/06

    CPC分类号： A61B5/4041 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/0082 ,  A61B5/40 ,  A61B5/4029 ,  A61B5/6821 ,  A61B5/7225 ,  A61B5/7282 ,  A61N1/00 ,  A61N1/3605 ,  A61N5/0622

    摘要： Optical methods, devices, and systems for noninvasively detecting transient surface displacements in a neuron are disclosed. Methods, devices, and systems provided may employ a phase-sensitive optical low coherence reflectometer. In addition, surface displacements due to action potential propagation in neural tissues may be detected in some embodiments using back-reflected light. According to some embodiments, exogenous chemicals or reflect ion coatings are not required. Transient neural surface displacement of less then 1 nm in amplitude and 1 ms in duration may be detected and may be generally coincident with action potential arrival to the optical measurement site. The systems and methods may be used for noninvasive detection of various neuropathies such as retinal neuropathies. They may also be useful in detecting the effects of various pharmacological agents.

    摘要翻译： 公开了用于非侵入性地检测神经元中的瞬时表面位移的光学方法，装置和系统。 提供的方法，设备和系统可以采用相敏光学低相干反射计。 此外，在使用反射反射光的一些实施例中，可以检测由于神经组织中的动作电位传播引起的表面位移。 根据一些实施方案，不需要外源化学品或反射离子涂层。 可以检测到幅度小于1nm，持续时间为1ms的瞬态神经表面位移，并且可能通常与到达光学测量位置的动作电位一致。 系统和方法可以用于各种神经病如视网膜神经病的非侵入性检测。 它们也可用于检测各种药理学试剂的作用。

    System and method for facial nerve monitoring during facial surgery
    44.
    发明授权
    System and method for facial nerve monitoring during facial surgery 有权
    面部神经监护系统及方法

    公开(公告)号：US08680986B2

    公开(公告)日：2014-03-25

    申请号：US13296138

    申请日：2011-11-14

    申请人： Peter Costantino

    发明人： Peter Costantino

    IPC分类号： G08B1/08

    CPC分类号： A61B5/1107 ,  A61B5/0024 ,  A61B5/0488 ,  A61B5/1123 ,  A61B5/4041 ,  A61B5/4893 ,  A61B5/6814 ,  A61B5/742 ,  A61B2505/05

    摘要： An apparatus for monitoring the activity of a surgeon. At least one wireless sensing unit is provided for monitoring potential damage to a nerve and is located at a first location of a body being operated on by a surgeon. The wireless sensing unit senses a change in the body at the first location resulting from potential damage to the nerve occurring at a second location of the body remote from the first location. The wireless sensing unit produces a wireless sensed change output signal indicative of the change in the body which is received by a receiver and generates a corresponding received output signal. An analyzer unit receives and analyzes the received output signal to determine the change in the body. An indicator responsive to the output of said analyzer unit indicates the change in the body to indicate the potential damage to the nerve the surgeon.

    摘要翻译： 一种用于监测外科医生的活动的装置。 提供至少一个无线感测单元用于监测对神经的潜在损伤，并且位于由外科医生操作的身体的第一位置。 无线感测单元感测由于对远离第一位置的身体的第二位置处的神经的潜在损伤造成的第一位置处的身体变化。 无线感测单元产生指示由接收机接收的身体变化的无线感测变化输出信号，并产生相应的接收输出信号。 分析器单元接收并分析所接收的输出信号以确定身体的变化。 响应于所述分析器单元的输出的指示器指示身体的变化，以指示外科医生对神经的潜在损伤。

    Electrode
    45.
    发明授权
    Electrode 有权
    电极

    公开(公告)号：US08608664B2

    公开(公告)日：2013-12-17

    申请号：US13000221

    申请日：2009-06-19

    申请人： Takato Kunitake ,  Hiroshi Kannan

    发明人： Takato Kunitake ,  Hiroshi Kannan

    IPC分类号： A61B5/05

    CPC分类号： A61B5/04001 ,  A61B5/4041 ,  A61B2562/0217 ,  A61B2562/125

    摘要： An object of the present invention is to provide a microelectrode capable of recording action potentials of nerve cellsneurons as large-amplitude waveforms and being appropriate for multi-channeling. The electrode 1 of the present invention comprises a conductive linear core material 2, an insulating coating layer 3a with which the outer circumference of the linear core material is coated, and an extending part 3b formed by extending the end part of the coating layer on one tip side of the linear core material beyond the tip in the longitudinal direction of the linear core material, in which a cavity that opens in the extending direction is formed within the extending part.

    摘要翻译： 本发明的目的是提供能够将神经细胞神经元的动作电位记录为大振幅波形并适合于多通道的微电极。 本发明的电极1包括导电线性芯材料2，涂覆有线芯材的外周的绝缘涂层3a和通过将涂层的端部延伸在一个上而形成的延伸部分3b 直线芯材的尖端在直线芯材的纵向方向上超过尖端，其中沿延伸方向开口的空腔形成在延伸部分内。

    METHOD OF DIAGNOSIS AND LOCATION OF A SOFT TISSUE INJURY
    47.
    发明申请
    METHOD OF DIAGNOSIS AND LOCATION OF A SOFT TISSUE INJURY 审中-公开
    诊断方法和软组织损伤的位置

    公开(公告)号：US20130204158A1

    公开(公告)日：2013-08-08

    申请号：US13700375

    申请日：2011-05-23

    申请人： Mark John McDonald Rogers

    发明人： Mark John McDonald Rogers

    IPC分类号： A61B5/00 ,  A61B5/01

    CPC分类号： A61B5/4824 ,  A61B5/0059 ,  A61B5/0082 ,  A61B5/015 ,  A61B5/4041 ,  A61B5/4552 ,  A61B5/4884

    摘要： A method of diagnosing, and determining the position of a microscopic or a macroscopic soft tissue injury or soft tissue stress fracture in a patient. The method includes the steps of determining a pain area on the skin of the patient, applying electromagnetic energy or radiation in a selected portion or range of the visible or infrared spectrums, to parts of the body's surface that correspond with the pain area, obtaining feedback from the patient to determine the sensations that the patient experiences as a result of visible or infrared energy being applied to the tissue at a specific region of pain area, and establishing the site of the microscopic or macroscopic soft tissue injury at the specific region where the sensations are greatest. The visible or infrared energy can be applied using a laser probe. The probe can operated at a selected wavelength or a set of wavelengths in the range of 400 nm to 10,000 ran. The soft tissue injuries to which the present invention may be applicable include injuries that result in symptoms including lower back pain, neck pain, migraines, Type 2 diabetes, sciatica, tinnitus, carpal tunnel syndrome, chronic pain syndrome and fibromyalgia.

    摘要翻译： 诊断和确定患者微观或肉眼软组织损伤或软组织应力性骨折的位置的方法。 该方法包括以下步骤：确定患者皮肤上的疼痛区域，将可见光或红外光谱的所选部分或范围内的电磁能或辐射施加到与疼痛区域相对应的身体表面的部分，获得反馈 从患者确定由于可见或红外能量被施加到疼痛区域的特定区域处的组织而导致患者体验的感觉，并且在特定区域建立微观或宏观软组织损伤的部位，其中 感觉最大 可以使用激光探头来施加可见光或红外能量。 探头可以在400nm至10,000nm范围内的选定波长或一组波长下操作。 可以应用本发明的软组织损伤包括导致症状的损伤，包括下腰痛，颈痛，偏头痛，2型糖尿病，坐骨神经痛，耳鸣，腕管综合征，慢性疼痛综合征和纤维肌痛等症状。

    Electromagnetic apparatus and method for nerve localization during spinal surgery
    48.
    发明授权
    Electromagnetic apparatus and method for nerve localization during spinal surgery 失效
    脊髓手术中神经定位的电磁装置及方法

    公开(公告)号：US08500738B2

    公开(公告)日：2013-08-06

    申请号：US13200607

    申请日：2011-09-24

    申请人： Erich Wolf, II

    发明人： Erich Wolf, II

    IPC分类号： A61B17/16

    CPC分类号： A61B5/05 ,  A61B5/0488 ,  A61B5/4041 ,  A61B5/4836 ,  A61B17/1671 ,  A61B17/1703 ,  A61B2017/00039 ,  A61B2017/00154 ,  A61N1/0551

    摘要： An electromagnetic pedicle awl utilizes a tightly focused time-varying magnetic flux to create a localized electromotive force (EMF) near the tip. The localized EMF creates localized eddy currents in nearby nerves which excite ionic nerve channels, the excitation being detected by an electromyographic recording device. The awl only excites nerves directly in front of and directly to the side of the tip. The awl is comprised of a tapered awl or drill tip in combination with a solid core surrounded by a solenoid. A pulsed electric current source drives the solenoid to create a time-varying magnetic field in the vicinity of the tapered tip. The awl or drill tip may be stationary with respect to the solenoid or it may rotate. The awl in combination with an EMG detector connected to a patient is sensitive to the pedicle hole position with respect to adjacent nerves and reduces false placement failure.

    摘要翻译： 电磁椎弓根锥使用紧密集中的随时间变化的磁通量来产生尖端附近的局部电动势（EMF）。 局部EMF在附近的神经中产生局部涡流，激发离子神经通道，激发由肌电图记录装置检测。 锥只能直接在尖端前方直接刺激神经。 锥体由锥形锥体或钻头尖端组成，并与由螺线管包围的实芯组合。 脉冲电流源驱动螺线管，以在锥形尖端附近产生时变磁场。 锥头或钻头尖端可以相对于螺线管是静止的，或者它可以旋转。 与连接到患者的EMG检测器组合的锥体相对于相邻神经对椎弓根孔位置敏感并且减少假位置失败。

    Modulation of trigeminal reflex strength
    49.
    发明授权
    Modulation of trigeminal reflex strength 有权
    调节三叉神经反射强度

    公开(公告)号：US08457749B2

    公开(公告)日：2013-06-04

    申请号：US13078976

    申请日：2011-04-03

    申请人： Christopher Poletto

    发明人： Christopher Poletto

    IPC分类号： A61N1/18

    CPC分类号： A61N1/0551 ,  A61B5/04001 ,  A61B5/4041 ,  A61N1/0553 ,  A61N1/36075

    摘要： A method includes evoking and recording the response of a trigeminal reflex in the presence and absence of occipital nerve stimulation (ONS) to determine whether, and to what extent, ONS modulates the trigeminal reflex. If the ONS modulates the trigeminal reflex, e.g. to a sufficient degree, the subject may be considered a candidate for ONS for treatment of headache.

    摘要翻译： 一种方法包括在存在和不存在枕神经刺激（ONS）时唤起和记录三叉神经反射的反应，以确定ONS是否以及在多大程度上调节三叉神经反射。 如果ONS调节三叉神经反射，例如 在足够的程度上，该主题可被认为是治疗头痛的ONS的候选者。