摘要:
System to measure blood coagulation related parameters comprising one first channel (6) adapted to contain a blood sample; said system containing, at least partially, an expandable material which is able to increase its volume when activated by an exciting source; said system furthermore comprising several excitable regions distributed close to said first channel (6), in such a way that, when one of said excitable region is activated, said expandable material increases to such an extend that the channel cross section is reduced to a location situated at or near to said excitable region.
摘要:
Provided is a microfluidic device and microfluidic system with the device. The microfluidic device includes a substrate; a channel formed in the substrate and in which a fluid can move; a valve controlling flow of a fluid flowing along the channel and including a phase transition material which can be melted by energy such as electromagnetic wave energy; and a lens disposed on the substrate and adjusting an irradiating region of the valve, onto which the energy is applied.
摘要:
Provided are a valve filler and a valve unit including the valve filler. The valve filler includes: a phase transition material; and a heating fluid comprising a carrier oil and a plurality of micro heating particles suspended in the carrier oil, the heating fluid being mixed with the phase transition material, wherein, when external energy is supplied, the micro heating particles receive the external energy and generate heat to melt the phase transition material into a fluid state, and when no external energy is supplied, the phase transition material hardens into a solid state.
摘要:
Microfluidic valves constructed from elastomeric materials as the valve body components and employing shape memory alloy in wire form as the valve actuator. Various configurations of individual valves having both normally open and normally closed states are described. Apparatus using such valves and providing logic functionality with fluidic logic outputs are discussed. Apparatus that can be used for materials processing at the nano- or micro-scale are presented. Various forms of logical control of valve arrays are explained.
摘要:
A centrifugal force based microfluidic device including a thermal activation unit, a microfluidic system including the same, and a method of operating the microfluidic system are provided. The thermal activation unit accompanies a temperature change in order to carry out its functions and having heat generation particles that absorb electromagnetic waves and generate heat in the activation unit therein.
摘要:
A phase transition type valve is provided. The valve includes a phase transition material filled and hardened in a section of a channel and a tube expanding region which has a larger cross-sectional area than the channel formed at both ends of the section in which the phase transition material is hardened.
摘要:
A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.
摘要:
A substrate having a surface with reversibly switchable properties. The surface comprises a nanolayer of a material that switches from a first conformation state to a second conformation state when an external stimulus is applied. When the nanolayer is in the first conformation state, the surface is characterized by a first property, and when the nanolayer is in the second conformation state, the surface is characterized by a second property.
摘要:
A cast-in-place and lithographically shaped mobile, monolithic polymer element for fluid flow control in microfluidic devices and method of manufacture. Microfluid flow control devices, or microvalves that provide for control of fluid or ionic current flow can be made incorporating a cast-in-place, mobile monolithic polymer element, disposed within a microchannel, and driven by fluid pressure (either liquid or gas) against a retaining or sealing surface. The polymer elements are made by the application of lithographic methods to monomer mixtures formulated in such a way that the polymer will not bond to microchannel walls. The polymer elements can seal against pressures greater than 5000 psi, and have a response time on the order of milliseconds. By the use of energetic radiation it is possible to depolymerize selected regions of the polymer element to form shapes that cannot be produced by conventional lithographic patterning and would be impossible to machine.
摘要:
A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.