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    Apparatus and method for imaging ionizing radiation
    3.
    发明授权
    Apparatus and method for imaging ionizing radiation 有权
    用于成像电离辐射的装置和方法

    公开(公告)号：US08203132B2

    公开(公告)日：2012-06-19

    申请号：US12324092

    申请日：2008-11-26

    申请人： Gilbert Feke ,  Douglas O. Wood ,  Douglas L. Vizard

    发明人： Gilbert Feke ,  Douglas O. Wood ,  Douglas L. Vizard

    IPC分类号： G01N23/04

    CPC分类号： A61B5/0059 ,  A61B6/00 ,  A61B6/4216 ,  A61B6/5241 ,  A61B6/583 ,  G03B42/023 ,  G21K2004/06

    摘要： A system and method are disclosed for capturing a radiographic or autoradiographic image of an object, in which a support member is provided to receive the object in an immobilized state; a phosphor screen is provided to transduce ionizing radiation from the source to visible light; film or a digital capture device is provided for capturing an image using the visible light; and the phosphor screen is moved incrementally to facilitate reduction of phosphor screen mottle.

    摘要翻译： 公开了一种用于捕获物体的射线照相或放射自显影图像的系统和方法，其中提供支撑构件以在固定状态下接收物体; 提供荧光屏以将从源的电离辐射转换成可见光; 提供电影或数字捕获装置用于使用可见光捕获图像; 并且荧光屏逐渐移动以便于减少荧光屏斑点。

    Variable condenser for delivery of illumination including recursively nested circle to-line fiber optic converter cable
    4.
    发明授权
    Variable condenser for delivery of illumination including recursively nested circle to-line fiber optic converter cable 失效
    用于交付照明的可变冷凝器，包括递归嵌套的圆形到线光纤转换器电缆

    公开(公告)号：US08113702B2

    公开(公告)日：2012-02-14

    申请号：US12431823

    申请日：2009-04-29

    申请人： Gilbert Feke

    发明人： Gilbert Feke

    IPC分类号： F21V7/04

    CPC分类号： G02B6/04 ,  G02B6/0008 ,  G02B26/103

    摘要： A variable condenser for delivery of illumination, including a recursively nested circle-to-line fiber optic shape-converting cable and a focusable input lens system. At the input of the fiber optic cable, sets of individual optical fibers comprise successively smaller annuli recursively nested about a common center. At the output of the fiber optic cable, the sets of individual optical fibers comprise pairs of line segments recursively nested about the line midpoint, whereby the nesting level of the pairs of line segments has an exact or an approximate correspondence to the nesting level of the annuli. The output may be split into a plurality of lines, whereby the sets of individual optical fibers are distributed among the plurality of lines. The input lens system has a single adjustable focus means to vary the radius of an illumination spot incident upon the input of the fiber optic cable circle input.

    摘要翻译： 用于传输照明的可变电容器，包括递归嵌套的圆形到光纤形状转换电缆和可调焦输入透镜系统。 在光纤电缆的输入端，各组光纤包括相对较小的环，其相对于公共中心递归地嵌套。 在光纤电缆的输出处，各组光纤包括一对线段，其以线中点递归地嵌套，由此线段对的嵌套级别具有与嵌套级别的精确或近似对应关系 环形 输出可以被分成多条线，由此各组光纤分布在多条线之间。 输入透镜系统具有单个可调节聚焦装置，以改变入射到光纤光缆圆输入端的照明点的半径。

    Method and apparatus for multi-modal imaging
    5.
    发明授权
    Method and apparatus for multi-modal imaging 有权
    多模态成像的方法和装置

    公开(公告)号：US08041409B2

    公开(公告)日：2011-10-18

    申请号：US12460010

    申请日：2009-07-10

    申请人： Warren M. Leevy ,  Gilbert Feke ,  Douglas L. Vizard

    发明人： Warren M. Leevy ,  Gilbert Feke ,  Douglas L. Vizard

    IPC分类号： A61B6/00

    CPC分类号： A61B5/0059 ,  A01K1/031 ,  A61B5/0035 ,  A61B6/00 ,  A61B6/508 ,  A61B6/5247 ,  A61D7/04

    摘要： A method and apparatus for imaging a subject animal. The method comprises the steps of treating the animal with an x-ray contrast agent and an imaging agent; supporting the animal in an immobilized state on a support member; acquiring an x-ray anatomical image of the animal; acquiring an optical, dark-field image of the animal; and registering the x-ray anatomical image and the optical image, whereby features of the optical image can be observed in relation to features of the anatomical image.

    摘要翻译： 一种用于成像受试动物的方法和装置。 该方法包括用X射线造影剂和成像剂处理动物的步骤; 将动物以固定状态支撑在支撑构件上; 获取动物的x射线解剖图像; 获取动物的光学，暗视野图像; 并记录x射线解剖图像和光学图像，由此可以相对于解剖图像的特征观察光学图像的特征。

    TUNABLE SPECTRAL FILTRATION DEVICE
    6.
    发明申请
    TUNABLE SPECTRAL FILTRATION DEVICE 审中-公开
    可调光谱过滤装置

    公开(公告)号：US20100046076A1

    公开(公告)日：2010-02-25

    申请号：US12248958

    申请日：2008-10-10

    申请人： Gilbert Feke ,  Douglas L. Vizard

    发明人： Gilbert Feke ,  Douglas L. Vizard

    IPC分类号： G02B27/00 ,  G01J3/45

    CPC分类号： G02B5/285 ,  G02B26/002 ,  G02B26/008 ,  G02B26/023

    摘要： A tunable spectral filtration device is disclosed that includes one or more pairs of interference filters in series, wherein each element of each pair is independently selected from one or more options, independently positioned to intersect a path of converging or diverging light, and independently tilted with respect to the light path. Each filter may be either of a bandpass type, a shortpass type, a longpass type, a notch type, or multiple combinations thereof. Each filter in the series may be independently selected and tilted to tune the net spectral output of the series. The elements in a pair of filters may be tilted in opposite directions so as to cancel angle-of incidence dependent broadening of the spectral output of the individual filters for noncollimated light, as well as cancel translational shift of the transmitted light rays. The elements in a pair of filters may be tilted through orthogonal tilt axes so as to cancel polarization dependent broadening of the spectral output of the individual filters for light whose polarization state is a superposition of nonzero parallel and perpendicular components relative to the tilt axes.

    摘要翻译： 公开了一种可调谐光谱过滤装置，其包括一对或多对串联的干涉滤光器，其中每对的每个元件独立地选自一个或多个选项，独立地定位成与会聚光或发散光的路径相交，并独立地倾斜与 尊重光路。 每个滤波器可以是带通型，短路型，长通型，陷波型或其多种组合中的任一种。 可以独立地选择和倾斜系列中的每个滤光片以调节该系列的净光谱输出。 一对滤波器中的元件可以在相反的方向上倾斜，以便消除入射角依赖于非准直光的各个滤光器的光谱输出的变宽，以及消除透射光线的平移移动。 一对滤波器中的元件可以通过正交的倾斜轴倾斜，从而抵消偏振状态是相对于倾斜轴的非零平行和垂直分量的叠加的光的各个滤光器的光谱输出的偏振相关的加宽。

    Method and apparatus for measuring long bone density of small-animals
    8.
    发明授权
    Method and apparatus for measuring long bone density of small-animals 失效
    测量小动物长骨密度的方法和装置

    公开(公告)号：US07706501B2

    公开(公告)日：2010-04-27

    申请号：US12204132

    申请日：2008-09-04

    申请人： Douglas L. Vizard ,  Douglas O. Wood ,  William E. McLaughlin ,  Gilbert Feke ,  Rao Papineni

    发明人： Douglas L. Vizard ,  Douglas O. Wood ,  William E. McLaughlin ,  Gilbert Feke ,  Rao Papineni

    IPC分类号： G01N23/083 ,  G01B15/00

    CPC分类号： G01N23/087 ,  G01N2223/407 ,  G01N2223/6123

    摘要： A method and apparatus are disclosed for measuring long bone density of small animals. A phosphor screen or plate is provided of a type that transduces incident ionizing radiation to emitted light. A small animal is positioned before the phosphor screen or plate and exposed to soft X-radiation having an energy level in the range of 11 to 16 Kev. Light emitted by the phosphor screen or plate is captured using a digital camera and a digital X-ray image is prepared of a long bone of the animal. The X-ray image is transformed into an X-ray density image and a region of interest is defined on the long bone in the X-ray density image. At least one row of pixels is scanned within the region of interest of the X-ray density image. A nonlinear least squares analysis of data obtained from the scanning step is conducted using a cylindrical model for the long bone within the region of interest.

    摘要翻译： 公开了测量小动物长骨密度的方法和装置。 提供了将入射电离辐射转换为发射光的类型的荧光屏或板。 将小动物放置在荧光屏或板之前并暴露于能量水平在11至16Kev范围内的软X-辐射。 使用数字照相机捕获由荧光屏或板发射的光，并且制备动物的长骨的数字X射线图像。 将X射线图像转换为X射线密度图像，并且在X射线密度图像中的长骨上限定感兴趣区域。 在X射线密度图像的感兴趣区域内扫描至少一行像素。 从扫描步骤获得的数据的非线性最小二乘法分析是使用感兴趣区域内的长骨的圆柱模型进行的。

    VARIABLE CONDENSER FOR DELIVERY OF ILLUMINATION INCLUDING RECURSIVELY NESTED CIRCLE-TO-LINE FIBER OPTIC CONVERTER CABLE
    9.
    发明申请
    VARIABLE CONDENSER FOR DELIVERY OF ILLUMINATION INCLUDING RECURSIVELY NESTED CIRCLE-TO-LINE FIBER OPTIC CONVERTER CABLE 失效
    用于交付照明的可变式冷凝器，包括可重复使用的圆形光纤转换器电缆

    公开(公告)号：US20090273944A1

    公开(公告)日：2009-11-05

    申请号：US12431823

    申请日：2009-04-29

    申请人： Gilbert Feke

    发明人： Gilbert Feke

    IPC分类号： G02B6/00

    CPC分类号： G02B6/04 ,  G02B6/0008 ,  G02B26/103

    摘要： A variable condenser for delivery of illumination, including a recursively nested circle-to-line fiber optic shape-converting cable and a focusable input lens system. At the input of the fiber optic cable, sets of individual optical fibers comprise successively smaller annuli recursively nested about a common center. At the output of the fiber optic cable, the sets of individual optical fibers comprise pairs of line segments recursively nested about the line midpoint, whereby the nesting level of the pairs of line segments has an exact or an approximate correspondence to the nesting level of the annuli. The output may be split into a plurality of lines, whereby the sets of individual optical fibers are distributed among the plurality of lines. The input lens system has a single adjustable focus means to vary the radius of an illumination spot incident upon the input of the fiber optic cable circle input.

    摘要翻译： 用于传输照明的可变电容器，包括递归嵌套的圆形到光纤形状转换电缆和可调焦输入透镜系统。 在光纤电缆的输入端，各组光纤包括相对较小的环，其相对于公共中心递归地嵌套。 在光纤电缆的输出处，各组光纤包括一对线段，其以线中点递归地嵌套，由此线段对的嵌套级别具有与嵌套级别的精确或近似对应关系 环形 输出可以被分成多条线，由此各组光纤分布在多条线之间。 输入透镜系统具有单个可调节聚焦装置，以改变入射到光纤光缆圆输入端的照明点的半径。

    IMAGING TARGET FOR TESTING QUALITY OF MULTIPLE-MAGNIFICATION FOCUS AND IMAGE CO-REGISTRATION
    10.
    发明申请
    IMAGING TARGET FOR TESTING QUALITY OF MULTIPLE-MAGNIFICATION FOCUS AND IMAGE CO-REGISTRATION 有权
    用于测试多重放大焦点和图像共同注册质量的成像目标

    公开(公告)号：US20090067582A1

    公开(公告)日：2009-03-12

    申请号：US12195452

    申请日：2008-08-21

    申请人： Gilbert Feke

    发明人： Gilbert Feke

    IPC分类号： G01D18/00

    CPC分类号： A61B6/587 ,  A61B6/583 ,  H04N5/32

    摘要： An imaging target, suited for use in multi-modal imaging systems, includes test patterns for testing quality of both focus and co-registration for multiple magnifications and multiple modalities of operation of a multimodal imaging system.

    摘要翻译： 适用于多模式成像系统的成像目标包括用于测试多重放大倍数和多模式成像系统的多种操作模式的聚焦和共同对准质量的测试模式。