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    ARRANGEMENTS AND METHODS FOR MULTIDIMENSIONAL MULTIPLEXED LUMINESCENCE IMAGING AND DIAGNOSIS
    1.
    发明申请
    ARRANGEMENTS AND METHODS FOR MULTIDIMENSIONAL MULTIPLEXED LUMINESCENCE IMAGING AND DIAGNOSIS 审中-公开
    多元多光子成像和诊断的安排和方法

    公开(公告)号：US20080206804A1

    公开(公告)日：2008-08-28

    申请号：US12016051

    申请日：2008-01-17

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Leilei Peng ,  Tayyaba Hasan ,  Sarika Verma

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Leilei Peng ,  Tayyaba Hasan ,  Sarika Verma

    IPC分类号： C12Q1/02 ,  C12M1/34 ,  G01N21/63 ,  G01N21/76

    CPC分类号： G01N21/6408 ,  G01N21/6428 ,  G01N21/6445 ,  G01N21/6456 ,  G01N21/6489 ,  G01N33/582 ,  G01N2201/1296

    摘要： Exemplary embodiments of arrangements and methods providing information associated with a sample are described. For example, using such exemplary arrangements and methods, it is possible to receive an unpartitioned electro-magnetic radiation from the sample. Further, first data associated with first luminescent characteristics of at least one first molecule of the sample and second data associated with second luminescent characteristics of at least one second molecule of the sample can be obtained based on the unpartitioned electro-magnetic radiation. At least two of the photo-luminescent properties of the sample may be measured simultaneously as a function of the first and second data. Further, the information regarding the molecules of the sample may be determined as a function of the photo-luminescent properties.

    摘要翻译： 描述了提供与样本相关联的信息的布置和方法的示例性实施例。 例如，使用这样的示例性布置和方法，可以从样品接收未分割的电磁辐射。 此外，可以基于未分割的电磁辐射获得与样品的至少一个第一分子的第一发光特性相关联的第一数据和与样品的至少一个第二分子的第二发光特性相关的第二数据。 可以同时测量样品的至少两种光致发光性质作为第一和第二数据的函数。 此外，关于样品分子的信息可以根据光致发光性质来确定。

    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION
    6.
    发明申请
    SYSTEMS, METHODS AND COMPUTER-ACCESSIBLE MEDIUM WHICH PROVIDE MICROSCOPIC IMAGES OF AT LEAST ONE ANATOMICAL STRUCTURE AT A PARTICULAR RESOLUTION 有权
    系统，方法和计算机可访问介质，提供特定解决方案中至少一个解剖结构的微观图像

    公开(公告)号：US20110261366A1

    公开(公告)日：2011-10-27

    申请号：US13042230

    申请日：2011-03-07

    申请人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    发明人： Guillermo J. Tearney ,  Brett E. Bouma ,  Joseph A. Gardecki ,  Linbo Liu

    IPC分类号： G01B9/02

    CPC分类号： A61B5/0066 ,  A61B5/0044 ,  A61B5/0075 ,  A61B5/0084 ,  G01B9/02091 ,  G02B6/32

    摘要： Exemplary embodiments of systems and methods can be provided which can generate data associated with at least one portion of a sample. For example, at least one first radiation can be forwarded to the portion through at least one optical arrangement. At least one second radiation can be received from the portion which is based on the first radiation. Based on an interaction between the optical arrangement and the first radiation and/or the second radiation, the optical arrangement can have a first transfer function. Further, it is possible to forward at least one third radiation to the portion through such optical arrangement (or through another optical arrangement), and receive at least one fourth radiation from the portion which is based on the third radiation. Based on an interaction between the optical arrangement (or the other optical arrangement) and the third radiation and/or the fourth radiation, the optical arrangement (or the other optical arrangement) can have a second transfer function. The first transfer function can be at least partially different from the second transfer function. The data can be generated based on the second and fourth radiations.

    摘要翻译： 可以提供可以生成与样品的至少一部分相关联的数据的系统和方法的示例性实施例。 例如，可以通过至少一个光学布置将至少一个第一辐射转发到该部分。 可以从基于第一辐射的部分接收至少一个第二辐射。 基于光学布置和第一辐射和/或第二辐射之间的相互作用，光学装置可以具有第一传递函数。 此外，可以通过这种光学装置（或通过另一种光学装置）将至少一个第三辐射转发到该部分，并且从基于第三辐射的部分接收至少一个第四辐射。 基于光学布置（或另一个光学布置）与第三辐射和/或第四辐射之间的相互作用，光学布置（或另一个光学布置）可以具有第二传递函数。 第一传递函数可以至少部分地不同于第二传递函数。 可以基于第二和第四辐射来生成数据。

    SYSTEMS AND METHODS FOR PROVIDING BEAM SCAN PATTERNS FOR HIGH SPEED DOPPLER OPTICAL FREQUENCY DOMAIN IMAGING
    10.
    发明申请
    SYSTEMS AND METHODS FOR PROVIDING BEAM SCAN PATTERNS FOR HIGH SPEED DOPPLER OPTICAL FREQUENCY DOMAIN IMAGING 有权
    用于提供高速多普勒光学频域成像的光束扫描模式的系统和方法

    公开(公告)号：US20090036782A1

    公开(公告)日：2009-02-05

    申请号：US12183630

    申请日：2008-07-31

    申请人： Benjamin J. Vakoc ,  Guillermo J. Tearney ,  Brett E. Bouma

    发明人： Benjamin J. Vakoc ,  Guillermo J. Tearney ,  Brett E. Bouma

    IPC分类号： A61B5/00

    CPC分类号： A61B5/0261 ,  A61B5/0066 ,  A61B5/0073

    摘要： An exemplary apparatus and/or an exemplary method can be provided using which, it is possible (e.g., with at least one first arrangement) to measure an amplitude and/or a phase of at least one electromagnetic radiation provided from a particular portion of a sample. Further, it is possible (e.g., using at least one second arrangement) to scan a location of the particular portion along a path from a first point of the sample to a second point of the sample. In addition, it is possible to control the scan (e.g., with the second arrangement) such that the scan may comprise at least one first segment having a positive velocity and at least one segment having a negative velocity. A first distance of the first segment and/or the second segment can be smaller than a second distance between the first and second points.

    摘要翻译： 可以提供示例性的装置和/或示例性方法，其可以（例如，利用至少一个第一布置）来测量从特定部分提供的至少一个电磁辐射的幅度和/或相位 样品。 此外，可以（例如，使用至少一个第二布置）沿着从样品的第一点到样品的第二点的路径扫描特定部分的位置。 此外，可以控制扫描（例如，利用第二布置），使得扫描可以包括具有正速度的至少一个第一段和至少一个具有负速度的段。 第一段和/或第二段的第一距离可以小于第一和第二点之间的第二距离。