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    Fiber optic imaging endoscope interferometer with at least one faraday rotator
    4.
    发明授权
    Fiber optic imaging endoscope interferometer with at least one faraday rotator 失效
    具有至少一个法拉第旋转器的光纤成像内窥镜干涉仪

    公开(公告)号：US06501551B1

    公开(公告)日：2002-12-31

    申请号：US09414293

    申请日：1999-10-05

    申请人： Guillermo Tearney ,  Stephen A. Boppart ,  Brett E. Bouma ,  Mark Brezinski ,  Eric A. Swanson ,  James G. Fujimoto

    发明人： Guillermo Tearney ,  Stephen A. Boppart ,  Brett E. Bouma ,  Mark Brezinski ,  Eric A. Swanson ,  James G. Fujimoto

    IPC分类号： G01B902

    CPC分类号： G11B7/005 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00183 ,  A61B3/1005 ,  A61B3/102 ,  A61B5/0064 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/445 ,  A61B5/6852 ,  A61B2562/0242 ,  B82Y15/00 ,  G01B9/02002 ,  G01B9/02004 ,  G01B9/02007 ,  G01B9/0201 ,  G01B9/0205 ,  G01B9/02091 ,  G01B11/00 ,  G01B11/026 ,  G01B11/12 ,  G01B11/2441 ,  G01B2290/65 ,  G01B2290/70 ,  G01J1/00 ,  G01N21/4795 ,  G11B7/127 ,  G11B7/24 ,  G11B2007/0013 ,  H01S5/141

    摘要： An imaging system for performing optical coherence tomography includes an optical radiation source; a reference optical reflector; a first optical path leading to the reference optical reflector; and a second optical path coupled to an endoscopic unit. The endoscopic unit preferably includes an elongated housing defining a bore; a rotatable single mode optical fiber having a proximal end and a distal end positioned within and extending the length of the bore of the elongated housing; and an optical system coupled to the distal end of the rotatable single mode optical fiber, positioned to transmit the optical radiation from the single mode optical fiber to the structure and to transmit reflected optical radiation from the structure to the single mode optical fiber. The system further includes a beam divider dividing the optical radiation from the optical radiation source along the first optical path to the reflector and along the second optical path; and a detector positioned to receive reflected optical radiation from the reflector transmitted along the first optical path and reflected optical radiation transmitted from the structure along the second optical path. The detector generates a signal in response to the reflected optical radiation from the reference reflector and the reflected optical radiation from the structure, and a processor generating a image of the structure in response to the signal from the detector. The system provides both rotational and longitudinal scanning of an image.

    摘要翻译： 用于执行光学相干断层摄影的成像系统包括光辐射源; 参考光学反射器; 通向参考光反射器的第一光路; 以及耦合到内窥镜单元的第二光路。 内窥镜单元优选地包括限定孔的细长壳体; 可旋转的单模光纤，其具有定位在所述细长壳体的所述孔的长度内并延伸所述细长壳体的所述孔的长度的近端和远端; 以及耦合到可旋转单模光纤的远端的光学系统，定位成将光辐射从单模光纤传输到结构，并将反射的光辐射从结构传输到单模光纤。 该系统还包括一个光束分配器，将沿着第一光路的光辐射源的光辐射分成沿着第二光路; 以及检测器，其被定位成接收来自沿着第一光路传输的反射器的反射光辐射以及沿着第二光路从结构传输的反射光辐射。 检测器响应于来自参考反射器的反射光辐射和来自结构的反射光辐射产生信号，以及响应于来自检测器的信号产生结构图像的处理器。 该系统提供图像的旋转和纵向扫描。

    APPARATUS AND METHOD FOR PROVIDING INFORMATION FOR AT LEAST ONE STRUCTURE
    7.
    发明申请
    APPARATUS AND METHOD FOR PROVIDING INFORMATION FOR AT LEAST ONE STRUCTURE 审中-公开
    用于提供至少一个结构的信息的装置和方法

    公开(公告)号：US20080013960A1

    公开(公告)日：2008-01-17

    申请号：US11781722

    申请日：2007-07-23

    申请人： Guillermo Tearney ,  Brett Bouma ,  Milen Shishkov ,  Jonathan Rosen

    发明人： Guillermo Tearney ,  Brett Bouma ,  Milen Shishkov ,  Jonathan Rosen

    IPC分类号： H04B10/02

    CPC分类号： A61B5/0059 ,  A61B1/00096 ,  A61B1/0017 ,  A61B1/043 ,  A61B1/07 ,  A61B5/0062 ,  A61B5/0071 ,  A61B5/0084 ,  G02B21/0036 ,  G02B21/0048 ,  G02B21/0064

    摘要： A spectrally encoded endoscopic probe having high resolution and small diameter comprising at least one flexible optical fiber; an energy source; a grating through which said energy is transmitted such that the energy spectrum is dispersed; a lens for focusing the dispersed energy spectrum onto a sample such that the impingement spot for each wavelength is a separate position on the sample, the wavelength spectrum defining a wavelength encoded axis; means for mechanically scanning the sample with focused energy in a direction perpendicular to the wavelength encoded axis; a means for receiving energy reflected from the sample; and, a means for detecting the received reflected energy. The probe grating and lens delivers a beam of multi-spectral light having spectral components extending in one dimension across a target region and which is moved to scan in another direction. The reflected spectrum is measured to provide two dimensional imaging of the region.

    摘要翻译： 一种具有高分辨率和小直径的光谱编码内窥镜探针，包括至少一个柔性光纤; 能源; 所述能量通过所述光栅传播，使得能谱被分散; 用于将分散的能谱聚焦到样品上的透镜，使得每个波长的冲击点是样品上的分离位置，所述波长谱定义波长编码轴; 用于在垂直于波长编码轴的方向上以聚焦能量机械扫描样品的装置; 用于接收样品反射的能量的方法; 以及用于检测所接收的反射能量的装置。 探测光栅和透镜提供具有在一个维度上延伸穿过目标区域并且被移动以沿另一个方向扫描的光谱分量的多光谱光束。 测量反射光谱以提供该区域的二维成像。

    Apparatus, method and system for performing phase-resolved optical frequency domain imaging
    9.
    发明申请
    Apparatus, method and system for performing phase-resolved optical frequency domain imaging 有权
    用于执行相位分辨光学频域成像的装置，方法和系统

    公开(公告)号：US20060279742A1

    公开(公告)日：2006-12-14

    申请号：US11445990

    申请日：2006-06-01

    申请人： Guillermo Tearney ,  Brett Bouma ,  Johannes De Boer ,  Benjamin Vakoc ,  Seok-Hyun Yun

    发明人： Guillermo Tearney ,  Brett Bouma ,  Johannes De Boer ,  Benjamin Vakoc ,  Seok-Hyun Yun

    IPC分类号： G01B11/02

    CPC分类号： A61B5/0073 ,  A61B5/0066 ,  A61B2560/0223 ,  G01B9/02091 ,  G01N21/45 ,  G01N21/4795 ,  G01N21/49

    摘要： Apparatus, system and method are provided which utilize signals received from a reference and a sample. In particular, a radiation is provided which includes at least one first electromagnetic radiation directed to the sample and at least one second electromagnetic radiation directed to the reference. A frequency of the radiation varies over time. An interference can be detected between at least one third radiation associated with the first radiation and at least one fourth radiation associated with the second radiation. It is possible to obtain a particular signal associated with at least one phase of at least one frequency component of the interference, and compare the particular signal to at least one particular information. Further, it is possible to receive at least one portion of the radiation and provide a further radiation, such that the particular signal can be calibrated based on the further signal.

    摘要翻译： 提供了使用从参考和样本接收的信号的装置，系统和方法。 特别地，提供辐射，其包括指向样品的至少一个第一电磁辐射和指向参考的至少一个第二电磁辐射。 辐射的频率随时间而变化。 可以在与第一辐射相关联的至少一个第三辐射与与第二辐射相关联的至少一个第四辐射之间检测干扰。 可以获得与干扰的至少一个频率分量的至少一个相位相关联的特定信号，并将特定信号与至少一个特定信息进行比较。 此外，可以接收辐射的至少一部分并提供另外的辐射，使得可以基于另外的信号来校准特定信号。

    Devices and arrangements for performing coherence range imaging using a common path interferometer
    10.
    发明申请
    Devices and arrangements for performing coherence range imaging using a common path interferometer 有权
    使用公共路径干涉仪进行相干距离成像的装置和装置

    公开(公告)号：US20060109478A1

    公开(公告)日：2006-05-25

    申请号：US11285301

    申请日：2005-11-21

    申请人： Guillermo Tearney ,  Brett Bouma

    发明人： Guillermo Tearney ,  Brett Bouma

    IPC分类号： G01B9/02

    CPC分类号： A61B5/6852 ,  A61B5/0066 ,  G01B9/02004 ,  G01B9/02044 ,  G01B9/0205 ,  G01B9/02057 ,  G01B9/02091 ,  G01B2290/70 ,  G01D5/35303 ,  G01N21/4795

    摘要： Devices, arrangements and apparatus adapted to propagate at least one electro-magnetic radiation are provided. In particular, a probe housing, a sample arm section and a reference arm section can be included. For example, the sample arm section can be at least partially situated within the probe housing, and configured to propagate a first portion of the electro-magnetic radiation that is intended to be forwarded to a sample. The reference arm section can be at least partially situated within the probe housing, and configured to propagate a second portion of the electro-magnetic radiation that is intended to be forwarded to a reference. In addition or as an alternative, an interferometer may be situated within the probe housing. The first and second portions may travel along substantially the same paths, and the electro-magnetic radiation can be generated by a narrowband light source that has a tunable center wavelength. Further, the first and second portions may be at least partially transmitted via at least one optical fiber. A splitting arrangement may be provided which splits the electro-magnetic radiation into the first and second portions, and positioned closer to the sample than to the source of the electro-magnetic radiation, and the first and second portions may be adapted to propagate in different directions. An apparatus may be provided that is configured to control an optical path length of the second portion.

    摘要翻译： 提供适于传播至少一个电磁辐射的装置，装置和装置。 特别地，可以包括探针壳体，样品臂部分和参考臂部分。 例如，样品臂部分可以至少部分地位于探针壳体内，并且被配置为传播旨在被转发到样品的电磁辐射的第一部分。 参考臂部分可以至少部分地位于探针壳体内，并且被配置为传播旨在被转发到参考的电磁辐射的第二部分。 另外或作为替代，干涉仪可以位于探针外壳内。 第一和第二部分可以沿着基本上相同的路径行进，并且电磁辐射可以由具有可调谐中心波长的窄带光源产生。 此外，第一和第二部分可以经由至少一根光纤至少部分地传输。 可以提供分裂装置，其将电磁辐射分裂成第一和第二部分，并且比电磁辐射源更靠近样品定位，并且第一和第二部分可适于以不同的方式传播 方向。 可以提供被配置为控制第二部分的光路长度的装置。