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公开(公告)号:US08764279B2
公开(公告)日:2014-07-01
申请号:US13054130
申请日:2009-07-15
IPC分类号: B81B1/00
CPC分类号: B01F5/0645 , B01F13/0059
摘要: Static mixers and fluid systems incorporating one or more of the static mixers. The static mixers include a mixing structure formed within a body, wherein fluid flowing through the mixing structure defines a downstream direction through the mixing structure. The mixing structure includes a series of Y-shaped channels that cross to provide flowpaths that result in efficient mixing.
摘要翻译: 包含一个或多个静态混合器的静态混合器和流体系统。 静态混合器包括在体内形成的混合结构,其中流过混合结构的流体通过混合结构限定下游方向。 混合结构包括一系列Y形通道,其交叉以提供导致有效混合的流动路径。
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公开(公告)号:US20110176965A1
公开(公告)日:2011-07-21
申请号:US13054130
申请日:2009-07-15
CPC分类号: B01F5/0645 , B01F13/0059
摘要: Static mixers and fluid systems incorporating one or more of the static mixers. The static mixers include a mixing structure formed within a body, wherein fluid flowing through the mixing structure defines a downstream direction through the mixing structure. The mixing structure includes a series of Y-shaped channels that cross to provide flowpaths that result in efficient mixing.
摘要翻译: 包含一个或多个静态混合器的静态混合器和流体系统。 静态混合器包括在体内形成的混合结构,其中流过混合结构的流体通过混合结构限定下游方向。 混合结构包括一系列Y形通道,其交叉以提供导致有效混合的流动路径。
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公开(公告)号:US07932090B2
公开(公告)日:2011-04-26
申请号:US10911875
申请日:2004-08-05
CPC分类号: B01L9/527 , B01J19/0046 , B01J2219/00387 , B01J2219/00527 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/0061 , B01J2219/00612 , B01J2219/00621 , B01J2219/00659 , B01J2219/00677 , B01J2219/00689 , B01J2219/00693 , B01J2219/0072 , B01L3/5027 , B01L2200/025 , B01L2300/043 , B01L2300/0654 , B01L2300/0829 , G01N21/03 , G01N2021/0346 , Y10T436/11 , Y10T436/113332 , Y10T436/115831
摘要: Apparatus and methods for positioning the process chambers of microfluidic sample processing devices in the proper focal plane of a microplate reader are disclosed. The apparatus and methods may be adaptable to position the sample processing devices at different heights as may be necessary for processing in different microplate readers. A positioning device is used in connection with the sample processing device to locate the process chambers within the focal plane of the microplate reader.
摘要翻译: 公开了用于将微流体样品处理装置的处理室定位在酶标仪的适当焦平面中的装置和方法。 该装置和方法可以适用于将样品处理装置定位在不同高度处,这可能需要用于在不同的酶标板读取器中进行处理。 定位装置与样品处理装置结合使用以将处理室定位在酶标仪的焦平面内。
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公开(公告)号:US20100129878A1
公开(公告)日:2010-05-27
申请号:US12596346
申请日:2008-04-25
申请人: Ranjani V. Parthasarathy , Hsi-Chou Liu , Wensheng Xia , Assumpta Bennaars-Eiden , Paul N. Holt , William Bedingham , Christopher R. Kokaisel , Jeffrey C. Pederson
发明人: Ranjani V. Parthasarathy , Hsi-Chou Liu , Wensheng Xia , Assumpta Bennaars-Eiden , Paul N. Holt , William Bedingham , Christopher R. Kokaisel , Jeffrey C. Pederson
IPC分类号: C12P19/34
CPC分类号: B01L3/502753 , B01L7/52 , B01L2200/0647 , B01L2300/0806 , B01L2400/0677 , C12Q1/6806 , C12Q1/6846 , C12Q2563/149 , C12Q2563/137
摘要: The present invention provides methods for amplifying nucleic acid after isolating nucleic acid from a sample using functionalized support material.
摘要翻译: 本发明提供了使用官能化载体材料从样品中分离核酸后扩增核酸的方法。
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公开(公告)号:US20130109080A1
公开(公告)日:2013-05-02
申请号:US13699763
申请日:2011-05-23
申请人: Joel R. Dufresne , David J. Franta , Theresa J. Gerten , Christopher R. Kokaisel , Kurt J. Halverson , William Bedingham , James E. Aysta , Barry W. Robole , Kenneth B. Wood
发明人: Joel R. Dufresne , David J. Franta , Theresa J. Gerten , Christopher R. Kokaisel , Kurt J. Halverson , William Bedingham , James E. Aysta , Barry W. Robole , Kenneth B. Wood
IPC分类号: B01L3/00
CPC分类号: B01L3/50273 , B01L3/5025 , B01L3/502707 , B01L3/502738 , B01L3/523 , B01L7/52 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887
摘要: Methods and devices for the thermal processing of samples are disclosed, including portable, integrated processing assemblies for occluding channels in a fluidic device.
摘要翻译: 公开了用于样品热处理的方法和装置,包括用于在流体装置中封闭通道的便携式集成处理组件。
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公开(公告)号:US07445752B2
公开(公告)日:2008-11-04
申请号:US10929044
申请日:2004-08-27
申请人: Michael R. Harms , William Bedingham , Christopher R. Kokaisel , Barry W. Robole , Kenneth B. Wood
发明人: Michael R. Harms , William Bedingham , Christopher R. Kokaisel , Barry W. Robole , Kenneth B. Wood
CPC分类号: G01N35/00069 , B01L3/5025 , B01L3/50255 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2200/142 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/0409 , B01L2400/0481 , B01L2400/0655 , B01L2400/0661 , F27B9/16 , F27D5/00 , Y10T436/25 , Y10T436/2575
摘要: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas. The carriers may be used to apply selective compression to the sample processing devices.
摘要翻译: 同时公开了多个样品的热处理方法和装置。 组件包括具有过程阵列的载体和样品处理装置,其包括可用于将样品材料分配到与主管道流体连通的组pf处理室的导管。 样品处理装置可以包括以下各种组合中的一个或多个以下特征:可变形密封件,通过在偏移位置处离开主管道的进料管道连接到主管道的处理室,U形加载室和熔融粘合的组合 和粘合区域。 载体可用于对样品处理装置施加选择性压缩。
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公开(公告)号:USD492792S1
公开(公告)日:2004-07-06
申请号:US29172950
申请日:2002-12-19
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公开(公告)号:US20110117607A1
公开(公告)日:2011-05-19
申请号:US12617905
申请日:2009-11-13
申请人: William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole , Christopher R. Kokaisel
发明人: William Bedingham , Peter D. Ludowise , Jeffrey C. Pederson , Barry W. Robole , Christopher R. Kokaisel
CPC分类号: B01L7/52 , B01L2300/0803 , B01L2300/1811 , B01L2300/1822 , B01L2300/1827 , B01L2300/1883
摘要: Systems and methods for processing sample processing devices. The system can include a base plate adapted to rotate about a rotation axis. The base plate can include at least one first magnetic element. The system can further include an annular cover, and a sample processing device comprising at least one thermal process chamber. The annular cover can include an inner edge, an outer edge, and at least one second magnetic element. The method can include positioning the sample processing device between the base plate and the annular cover, such that the inner edge of the annular cover is positioned inwardly of the at least one thermal process chamber, and such that the at least one first magnetic element attracts the at least one second magnetic element to force the annular cover in a first direction along the z-axis, urging the sample processing device into contact with the base plate.
摘要翻译: 用于处理样品处理装置的系统和方法。 该系统可以包括适于围绕旋转轴线旋转的基板。 基板可以包括至少一个第一磁性元件。 该系统还可以包括环形盖,以及包括至少一个热处理室的样品处理装置。 环形盖可以包括内边缘,外边缘和至少一个第二磁性元件。 该方法可以包括将样品处理装置定位在基板和环形盖之间,使得环形盖的内边缘位于至少一个热处理室的内部,并且使得至少一个第一磁性元件吸引 所述至少一个第二磁性元件沿着z轴沿第一方向推动所述环形盖,迫使所述样品处理装置与所述基板接触。
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公开(公告)号:US07595200B2
公开(公告)日:2009-09-29
申请号:US11497828
申请日:2006-08-02
申请人: William Bedingham , Chad J. Carter , Robert A. Harkins , Michael R. Harms , Christopher R. Kokaisel , Diane North , Kenneth B. Wood
发明人: William Bedingham , Chad J. Carter , Robert A. Harkins , Michael R. Harms , Christopher R. Kokaisel , Diane North , Kenneth B. Wood
CPC分类号: G01N35/00069 , B01L3/5025 , B01L3/50255 , B01L3/502707 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L9/527 , B01L2200/0642 , B01L2200/0689 , B01L2200/142 , B01L2300/0654 , B01L2300/0816 , B01L2300/0864 , B01L2300/0887 , B01L2400/0406 , B01L2400/0409 , B01L2400/0481 , B01L2400/0655 , B01L2400/0661 , F27B9/16 , F27D5/00 , Y10T436/25 , Y10T436/2575
摘要: Methods and devices for thermal processing of multiple samples at the same time are disclosed. The assemblies include carriers and sample processing devices with process arrays that include conduits useful in distributing sample materials to a group pf process chambers located in fluid communication with the main conduits. The sample processing devices may include one or more of the following features in various combinations: deformable seals, process chambers connected to the main conduit by feeder conduits exiting the main conduit at offset locations, U-shaped loading chambers, and a combination of melt bonded and adhesively bonded areas. The carriers may be used to apply selective compression to the sample processing devices.
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公开(公告)号:US20080152546A1
公开(公告)日:2008-06-26
申请号:US11962669
申请日:2007-12-21
CPC分类号: B01L3/502738 , B01F11/0074 , B01F13/0059 , B01F15/0233 , B01L3/50273 , B01L2200/0668 , B01L2200/0684 , B01L2300/0806 , B01L2400/0409 , B01L2400/0677 , Y10T137/0329 , Y10T137/0753 , Y10T137/7758
摘要: Devices, systems, and methods for processing sample materials. The sample materials may be located in a plurality of process chambers in the device, which is rotated during heating of the sample materials.
摘要翻译: 用于处理样品的设备,系统和方法。 样品材料可以位于装置中的多个处理室中,其在样品材料的加热期间旋转。
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