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    DUAL GRADIENT MANAGED PRESSURE DRILLING
    1.
    发明申请
    DUAL GRADIENT MANAGED PRESSURE DRILLING 有权
    双级管理压力钻井

    公开(公告)号：US20130192841A1

    公开(公告)日：2013-08-01

    申请号：US13752804

    申请日：2013-01-29

    Applicant: Guy F. Feasey ,  David Pavel ,  Mark A. Mitchell

    Inventor： Guy F. Feasey ,  David Pavel ,  Mark A. Mitchell

    IPC: E21B21/08

    CPC classification number: E21B21/08 ,  E21B7/12 ,  E21B21/001

    Abstract: A method of drilling a subsea wellbore includes drilling the wellbore by injecting drilling fluid through a tubular string extending into the wellbore from an offshore drilling unit (ODU) and rotating a drill bit disposed on a bottom of the tubular string. The method further includes, while drilling the wellbore: mixing lifting fluid with drilling returns at a flow rate proportionate to a flow rate of the drilling fluid, thereby forming a return mixture. The lifting fluid has a density substantially less than a density of the drilling fluid. The return mixture has a density substantially less than the drilling fluid density. The method further includes, while drilling the wellbore: measuring a flow rate of the returns or the return mixture; and comparing the measured flow rate to the drilling fluid flow rate to ensure control of a formation being drilled.

    Abstract translation: 钻井海底钻井的方法包括通过从钻井单元（ODU）延伸到井筒中的管柱注入钻井液并旋转设置在管柱的底部上的钻头来钻井孔。 该方法还包括：在钻井井的同时：将提升液与钻井液混合，流量与钻井液的流量成比例，从而形成回流混合物。 提升流体的密度显着小于钻井液的密度。 回流混合物的密度显着小于钻井液密度。 该方法还包括在钻井井时：测量回油或回流混合物的流速; 并将测量的流量与钻井液流量进行比较，以确保正在钻取的地层的控制。

    Transfering database workload among multiple database systems
    2.
    发明授权
    Transfering database workload among multiple database systems 有权
    在多个数据库系统之间传输数据库工作负载

    公开(公告)号：US07567990B2

    公开(公告)日：2009-07-28

    申请号：US11638647

    申请日：2006-12-13

    Applicant: Mark A. Mitchell ,  Thomas A. Fastner

    Inventor： Mark A. Mitchell ,  Thomas A. Fastner

    IPC: G06F17/00

    CPC classification number: G06F17/30575 ,  Y10S707/99953

    Abstract: A system includes at least two database systems that both store a common portion of a relational database and that are configured to share in execution of a database workload against that relational database. The system also includes a system-management component configured to receive indication that a first one of the database systems is ceasing operation and, in response, take a second one of the database systems to an operational state in which at least a portion of the database workload that is scheduled to be carried out by the first database system is transferred to the second database system.

    Abstract translation: 系统包括至少两个数据库系统，其两者都存储关系数据库的公共部分，并且被配置为在针对该关系数据库执行数据库工作负载时共享。 系统还包括被配置为接收数据库系统中的第一个停止操作的指示的系统管理组件，并且作为响应，使数据库系统中的第二个数据库系统处于操作状态，其中数据库的至少一部分 计划由第一数据库系统执行的工作负载被传送到第二数据库系统。

    Continuously-operable flow stream processing system and method
    3.
    发明授权
    Continuously-operable flow stream processing system and method 有权

    公开(公告)号：US10239009B2

    公开(公告)日：2019-03-26

    申请号：US13827855

    申请日：2013-03-14

    Applicant: Mark A. Mitchell ,  Brian Anderson

    Inventor： Mark A. Mitchell ,  Brian Anderson

    IPC: B01D29/00 ,  B01D29/60 ,  B01D29/66 ,  B01D46/18 ,  B01D46/00

    Abstract: A continuously-operable flow stream processing system and method has two or more fluid processing media arranged in a fluid conduit network to provide alternate flow paths for a flow stream to be processed (e.g. filtered). Valves and other flow control devices, e.g. controller module and sensors, are used to redirect the flow stream from one or more service-needed fluid processing media to service-ready fluid processing media without taking the system offline to remove, repair, replace, clean in situ, or otherwise service the service-needed fluid processing media, so that the system may operate continuously to process the flow stream without stoppage. Redirection into alternative flow paths and media may be automatically implemented based on a predetermined threshold or trigger condition, such as may be detected by sensors directly or indirectly monitoring media condition.

    Engine intake air flow control assembly
    4.
    发明授权
    Engine intake air flow control assembly 有权
    发动机进气流量控制组件

    公开(公告)号：US08146564B2

    公开(公告)日：2012-04-03

    申请号：US12651674

    申请日：2010-01-04

    Applicant: Jian Jun Zhang ,  Mark A. Mitchell ,  Ko-Jen Wu

    Inventor： Jian Jun Zhang ,  Mark A. Mitchell ,  Ko-Jen Wu

    IPC: F02B31/08

    CPC classification number: F02M35/10085 ,  F02B31/06 ,  F02D9/1095 ,  Y02T10/146

    Abstract: An engine assembly may include a cylinder head, an intake manifold assembly, first and second vanes, and an actuation mechanism. The first and second vanes may be rotatably coupled to the intake manifold assembly. The first vane may be located within an outlet of a first intake passage and the second vane may be located within an outlet of a second intake passage. The first and second vanes may be displaceable from an open position to a closed position. The first vane may extend along a wall defining the first intake passage when in the open position and the second vane may extend along a wall defining the second intake passage when in the open position. The actuation mechanism may be coupled to the first and second vanes to rotate the first and second vanes between the open and closed positions.

    Abstract translation: 发动机组件可以包括气缸盖，进气歧管组件，第一和第二叶片以及致动机构。 第一和第二叶片可以可旋转地联接到进气歧管组件。 第一叶片可以位于第一进气通道的出口内，并且第二叶片可以位于第二进气通道的出口内。 第一和第二叶片可以从打开位置移动到关闭位置。 当处于打开位置时，第一叶片可以沿着限定第一进气通道的壁延伸，并且当处于打开位置时，第二叶片可以沿着限定第二进气通道的壁延伸。 致动机构可以联接到第一和第二叶片，以使第一和第二叶片在打开位置和关闭位置之间旋转。

    ENGINE INTAKE AIR FLOW CONTROL ASSEMBLY
    5.
    发明申请
    ENGINE INTAKE AIR FLOW CONTROL ASSEMBLY 有权
    发动机吸入空气流量控制装置

    公开(公告)号：US20110162611A1

    公开(公告)日：2011-07-07

    申请号：US12651674

    申请日：2010-01-04

    Applicant: JIAN JUN ZHANG ,  MARK A. MITCHELL ,  KO-JEN WU

    Inventor： JIAN JUN ZHANG ,  MARK A. MITCHELL ,  KO-JEN WU

    IPC: F02M35/10

    CPC classification number: F02M35/10085 ,  F02B31/06 ,  F02D9/1095 ,  Y02T10/146

    Abstract: An engine assembly may include a cylinder head, an intake manifold assembly, first and second vanes, and an actuation mechanism. The first and second vanes may be rotatably coupled to the intake manifold assembly. The first vane may be located within an outlet of a first intake passage and the second vane may be located within an outlet of a second intake passage. The first and second vanes may be displaceable from an open position to a closed position. The first vane may extend along a wall defining the first intake passage when in the open position and the second vane may extend along a wall defining the second intake passage when in the open position. The actuation mechanism may be coupled to the first and second vanes to rotate the first and second vanes between the open and closed positions.

    Abstract translation: 发动机组件可以包括气缸盖，进气歧管组件，第一和第二叶片以及致动机构。 第一和第二叶片可以可旋转地联接到进气歧管组件。 第一叶片可以位于第一进气通道的出口内，并且第二叶片可以位于第二进气通道的出口内。 第一和第二叶片可以从打开位置移动到关闭位置。 当处于打开位置时，第一叶片可以沿着限定第一进气通道的壁延伸，并且当处于打开位置时，第二叶片可以沿着限定第二进气通道的壁延伸。 致动机构可以联接到第一和第二叶片，以使第一和第二叶片在打开位置和关闭位置之间旋转。

    CC-1065 analogs
    7.
    发明授权
    CC-1065 analogs 失效
    CC-1065类似物

    公开(公告)号：US5739350A

    公开(公告)日：1998-04-14

    申请号：US479231

    申请日：1995-06-07

    Applicant: Robert C. Kelly ,  Mark A. Mitchell ,  Paul A. Aristoff

    Inventor： Robert C. Kelly ,  Mark A. Mitchell ,  Paul A. Aristoff

    IPC: A61K31/40 ,  A61K38/00 ,  A61K47/48 ,  A61P31/12 ,  A61P35/00 ,  C07D487/04 ,  C07D487/10 ,  C07F9/6561 ,  C07K1/113 ,  C07K5/06 ,  C07K5/062 ,  C07K5/08 ,  C07K16/00 ,  C07K17/06 ,  C07D487/08

    CPC classification number: C07D487/04 ,  A61K47/4813 ,  A61K47/48246 ,  A61K47/48407 ,  C07D487/10 ,  C07F9/6561 ,  C07K17/06 ,  C07K5/06026 ,  C07K5/06034 ,  C07K5/06043 ,  C07K5/06052 ,  C07K5/0802 ,  A61K38/00

    Abstract: This invention provides some new synthetically obtained compounds of formula I and II ##STR1## which are useful as chemical intermediates. Representative formula I or II compounds have also been shown to possess useful ranges of antitumor activity in standard laboratory animal tests. In addition, the compounds of formula I or II can be linked to monoclonal antibodies, either directly or via known linking group, as a means of selectively delivering the CC-1065 analogs (Compounds of Formula I and II) to those target cells expressing the target antigen and thus selectively eliminating those diseased cells from the animal or human. Further, the compounds of formula I and II can be linked to soluble human CD4 or a soluble human CD4 protein fragment capable of binding to the gp120 envelope protein of the human immuno-virus and thus eliminate virally infected cells.

    Abstract translation: 本发明提供一些新的合成的式I和II化合物，其可用作化学中间体。 代表性的式I或II化合物也已被证明在标准实验室动物试验中具有有效的抗肿瘤活性范围。 此外，式I或II的化合物可以直接或通过已知的连接基团与单克隆抗体连接，作为选择性递送CC-1065类似物（式I和II的化合物）到表达 靶抗原，从而选择性地从动物或人中除去那些患病细胞。 此外，式I和II的化合物可以与能够与人免疫病毒的gp120包膜蛋白结合的可溶性人CD4或可溶性人CD4蛋白片段连接，从而消除病毒感染的细胞。

    Continously-Operable Flow Stream Processing System and Method
    8.
    发明申请
    Continously-Operable Flow Stream Processing System and Method 审中-公开
    连续可行的流程处理系统和方法

    公开(公告)号：US20140263085A1

    公开(公告)日：2014-09-18

    申请号：US13827855

    申请日：2013-03-14

    Applicant: Mark A. Mitchell ,  Brian Anderson

    Inventor： Mark A. Mitchell ,  Brian Anderson

    IPC: B01D29/00 ,  B01D29/60 ,  B01D29/66

    CPC classification number: B01D46/18 ,  B01D46/0058

    Abstract: A continuously-operable flow stream processing system and method has two or more fluid processing media arranged in a fluid conduit network to provide alternate flow paths for a flow stream to be processed (e.g. filtered). Valves and other flow control devices, e.g. controller module and sensors, are used to redirect the flow stream from one or more service-needed fluid processing media to service-ready fluid processing media without taking the system offline to remove, repair, replace, clean in situ, or otherwise service the service-needed fluid processing media, so that the system may operate continuously to process the flow stream without stoppage. Redirection into alternative flow paths and media may be automatically implemented based on a predetermined threshold or trigger condition, such as may be detected by sensors directly or indirectly monitoring media condition.

    Abstract translation: 连续可操作的流动流处理系统和方法具有布置在流体管道网络中的两个或更多个流体处理介质，以为要处理（例如过滤）的流动流提供交替的流动路径。 阀和其它流量控制装置，例如 控制器模块和传感器用于将来自一个或多个服务需要的流体处理介质的流量重定向到服务就绪流体处理介质，而不使系统脱机以移除，修复，替换，原位清洁或以其他方式服务该服务 - 所需的流体处理介质，使得系统可以连续地操作以处理流动而不停止。 可以基于预定的阈值或触发条件自动实现重定向到替代流路径和媒体，诸如可以由传感器直接或间接地监视媒体条件来检测。

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