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158 条记录 (耗时 0.027 秒)

    Flexible Circuit Electrode Array with at Least one Tack Opening
    13.
    发明申请
    Flexible Circuit Electrode Array with at Least one Tack Opening 有权
    柔性电路电极阵列，至少一个开口

    公开(公告)号：US20080058875A1

    公开(公告)日：2008-03-06

    申请号：US11928698

    申请日：2007-10-30

    申请人： Robert Greenberg ,  Neil Talbot ,  Jordan Neysmith ,  James Little ,  Brian Mech

    发明人： Robert Greenberg ,  Neil Talbot ,  Jordan Neysmith ,  James Little ,  Brian Mech

    IPC分类号： A61N1/18

    CPC分类号： A61N1/0543 ,  A61N1/36046 ,  H05K1/036 ,  H05K1/0393 ,  H05K1/118 ,  H05K3/0014 ,  H05K2201/05 ,  H05K2201/053 ,  H05K2201/09063 ,  H05K2201/09409 ,  Y10T29/49002 ,  Y10T29/49117 ,  Y10T29/49155 ,  Y10T29/49156 ,  Y10T29/49158 ,  Y10T29/49174 ,  Y10T29/49176

    摘要： The present invention provides a flexible circuit electrode array adapted for neural stimulation, comprising: a polymer base layer; metal traces deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; a polymer top layer deposited on said polymer base layer and said metal traces at least one tack opening; wherein said polymer base layer, said metal traces and said polymer top layer are thermoformed in a three dimensional shape. The present invention provides further a method of making a flexible circuit electrode array comprising depositing a polymer base layer; depositing metal on said polymer base layer; patterning said metal to form metal traces; depositing a polymer top layer on said polymer base layer and said metal traces; preparing at least one tack opening; and heating said flexible circuit electrode array in a mold to form a three dimensional shape in said flexible circuit electrode array.

    摘要翻译： 本发明提供一种适用于神经刺激的柔性电路电极阵列，包括：聚合物基层; 沉积在所述聚合物基层上的金属痕迹，包括适于刺激神经组织的电极; 沉积在所述聚合物基层上的聚合物顶层和所述金属迹线至少一个粘性开口; 其中所述聚合物基层，所述金属迹线和所述聚合物顶层被热成型为三维形状。 本发明还提供一种制造柔性电路电极阵列的方法，包括沉积聚合物基层; 在所述聚合物基层上沉积金属; 图案化所述金属以形成金属痕迹; 在所述聚合物基底层和所述金属迹线上沉积聚合物顶层; 准备至少一个开口; 并将所述柔性电路电极阵列加热到模具中，以在所述柔性电路电极阵列中形成三维形状。

    Flexible Circuit Electrode Array
    14.
    发明申请
    Flexible Circuit Electrode Array 审中-公开

    公开(公告)号：US20080057179A1

    公开(公告)日：2008-03-06

    申请号：US11926046

    申请日：2007-10-28

    申请人： Robert Greenberg ,  Neil Talbot ,  Jordan Neysmith ,  Dilek Guven ,  James Little ,  Brian Mech ,  Mark Humayun

    发明人： Robert Greenberg ,  Neil Talbot ,  Jordan Neysmith ,  Dilek Guven ,  James Little ,  Brian Mech ,  Mark Humayun

    IPC分类号： B05D5/12

    摘要： Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow. Common flexible circuit fabrication techniques generally require that a flexible circuit electrode array be made flat. Since neural tissue is almost never flat, a flat array will necessarily apply uneven pressure. Further, the edges of a flexible circuit polymer array may be sharp and cut the delicate neural tissue. By applying the right amount of heat to a completed array, a curve can be induced. With a thermoplastic polymer it may be further advantageous to repeatedly heat the flexible circuit in multiple molds, each with a decreasing radius. Further, it is advantageous to add material along the edges. It is further advantageous to provide a fold or twist in the flexible circuit array. Additional material may be added inside and outside the fold to promote a good seal with tissue.

    Video processing methods for improving visual acuity and/or perceived image resolution
    17.
    发明申请
    Video processing methods for improving visual acuity and/or perceived image resolution 有权
    用于改善视力和/或感知图像分辨率的视频处理方法

    公开(公告)号：US20070299484A1

    公开(公告)日：2007-12-27

    申请号：US11880045

    申请日：2007-07-19

    申请人： Robert Greenberg ,  Richard Williamson ,  Joseph Schulman ,  Reza Rassol ,  Lee Mandell ,  Abraham Seidman

    发明人： Robert Greenberg ,  Richard Williamson ,  Joseph Schulman ,  Reza Rassol ,  Lee Mandell ,  Abraham Seidman

    IPC分类号： A61N1/00

    CPC分类号： A61N1/36046

    摘要： A method and apparatus for improving visual acuity when providing a visual image from a “high” resolution input device to a “low” resolution output device. The described invention is of particular use when the output device is an array of electrodes as part of a retinal prosthesis used to restore vision to a visually-impaired patient. In that various limitations may, within the foreseeable future, limit the density of such an electrode array (and thus the resolution of the output image), the present invention teaches techniques to assign processed pixel subsets of a higher resolution image to a single electrode. By varying the pixel subsets, e.g., by jittering, and/or altering the processing criteria, the perceived visual acuity may be further improved. Alternatively and additionally, such processing may be further extended to drive neighboring electrodes in combination to thus stimulate virtual electrode sites and thus further enhance visual acuity.

    摘要翻译： 当从“高”分辨率输入装置向“低”分辨率输出装置提供视觉图像时，用于提高视力的方法和装置。 当输出设备是用作将视力恢复到视觉障碍患者的视网膜假体的一部分的电极阵列时，所描述的本发明是特别有用的。 因此，在可预见的将来可能会限制这种电极阵列的密度（因此输出图像的分辨率）的各种限制，本发明教导了将更高分辨率图像的经处理的像素子集分配给单个电极的技术。 通过例如通过抖动和/或改变处理标准来改变像素子集，可以进一步改善感知的视敏度。 另外地和另外地，这样的处理可以进一步延伸以组合驱动相邻电极，从而刺激虚拟电极位置，从而进一步提高视敏度。

    Molded polymer comprising silicone and at least one metal trace and a process of manufacturing the same
    18.
    发明申请
    Molded polymer comprising silicone and at least one metal trace and a process of manufacturing the same 有权
    包含有机硅和至少一种金属痕迹的成型聚合物及其制造方法

    公开(公告)号：US20070292667A1

    公开(公告)日：2007-12-20

    申请号：US11810758

    申请日：2007-06-06

    申请人： Lucien Laude ,  Robert Greenberg

    发明人： Lucien Laude ,  Robert Greenberg

    IPC分类号： B32B3/00

    CPC分类号： H05K3/185 ,  A61N1/0543 ,  C23C18/1639 ,  C23C18/1653 ,  C23C18/1692 ,  C23C18/1868 ,  C23C18/1882 ,  C23C18/31 ,  H05K1/032 ,  H05K3/0035 ,  H05K3/107 ,  H05K3/465 ,  H05K3/4661 ,  H05K2201/0162 ,  H05K2201/096 ,  H05K2203/107 ,  Y10T428/24917 ,  Y10T428/31663

    摘要： The present invention provides a flexible electrode array, comprising a silicone containing body, at least one metal trace layer and at least one electrode pad on the surface. The present invention further provides a process of manufacturing a flexible electrode array, comprising: a) irradiating a surface area of a molded silicone containing layer yielding traces with a light beam emitted by a pulsed UV laser source, b) immersing said irradiated molded silicone layer for inducing the deposit of metal ions to form metal traces, c) applying a silicone containing layer on said silicone containing layer and said metal traces, d) irradiating the surface for drilling holes into the surface of the molded silicone containing layer, and e) immersing said irradiated molded silicone layer for inducing the deposit of metal ions to form metal electrode pads.

    摘要翻译： 本发明提供了一种柔性电极阵列，其包括硅氧烷容纳体，至少一个金属迹线层和表面上的至少一个电极焊盘。 本发明还提供一种制造柔性电极阵列的方法，包括：a）照射模制的含硅氧烷层的表面积，产生具有由脉冲UV激光源发射的光束的痕迹，b）将所述照射的模制硅氧烷层 用于诱导金属离子的沉积以形成金属迹线，c）在所述含硅层和所述金属迹线上施加含硅氧烷层，d）将所述表面照射到所述模制的含硅氧烷层的表面中，e） 浸渍所述照射的模制的硅氧烷层以诱导金属离子的沉积形成金属电极焊盘。

    Polymer layer comprising silicone and at least one metal trace and a process of manufacturing the same
    20.
    发明申请
    Polymer layer comprising silicone and at least one metal trace and a process of manufacturing the same 有权
    包含硅氧烷和至少一种金属痕迹的聚合物层及其制造方法

    公开(公告)号：US20070104944A1

    公开(公告)日：2007-05-10

    申请号：US11506617

    申请日：2006-08-17

    申请人： Lucien Laude ,  Robert Greenberg

    发明人： Lucien Laude ,  Robert Greenberg

    IPC分类号： B32B27/20 ,  C08L83/04 ,  B05D1/38

    CPC分类号： H05K3/185 ,  C08J7/12 ,  C08J2383/04 ,  C23C18/1608 ,  C23C18/1612 ,  C23C18/1657 ,  C23C18/204 ,  C23C18/206 ,  H05K3/28 ,  H05K3/387 ,  H05K2201/0133 ,  H05K2201/0162 ,  H05K2201/0209 ,  H05K2201/0236 ,  H05K2203/107 ,  H05K2203/1105 ,  Y10T428/26 ,  Y10T428/31663

    摘要： The present invention provides a process for embedding at least one layer of at least one metal trace in a silicone-containing polymer, comprising: a) applying a polymer layer on a substrate; b) thermally treating the polymer; c) irradiating at least one surface area of the polymer with a light beam emitted by an excimer laser; d) immersing the irradiated polymer in at least one autocatalytic bath containing ions of at least one metal, and metallizing the polymer; e) thermally treating the metallized polymer; f) applying a polymer layer covering the thermally treated metallized polymer; and g) thermally treating the metallized covered polymer. The present invention further provides a polymer layer comprising silicone containing oxide particles of SiO2, TiO2, Sb2O3, SnO2, Al2O3, ZnO, Fe2O3, Fe3O4, talc, hydroxyapatite or mixtures thereof and at least one metal trace embedded in said polymer layer. The present invention further provides a flexible electrode array comprising silicone containing oxide particles of SiO2, TiO2, Sb2O3, SnO2, A1203, ZnO, Fe2O3, Fe3O4, talc, hydroxyapatite or mixtures thereof and at least one metal trace embedded in said polymer layer.

    摘要翻译： 本发明提供了一种在含硅酮聚合物中嵌入至少一层至少一种金属痕迹的方法，包括：a）在基底上施加聚合物层; b）热处理聚合物; c）用由准分子激光器发射的光束照射所述聚合物的至少一个表面积; d）将经辐射的聚合物浸入至少一种含有至少一种金属的离子的自催化浴中，并对该聚合物进行金属化; e）热处理金属化聚合物; f）涂覆覆盖热处理的金属化聚合物的聚合物层; 和g）热处理金属化被覆聚合物。 本发明还提供一种聚合物层，其包含含硅氧烷的SiO 2，TiO 2，Sb 2 O 3， N 2，N 2 O 3，N 2，N 2 O 3， Fe 3 O 3，滑石，羟基磷灰石或其混合物，以及嵌入所述聚合物层中的至少一种金属迹线。 本发明还提供了一种柔性电极阵列，其包括含硅氧烷的SiO 2，TiO 2，Sb 2 O 3， / SUB>，SnO 2，Al 2 O 3，ZnO，Fe 2 O 3， Fe 3 O 3，滑石，羟基磷灰石或其混合物，以及嵌入所述聚合物层中的至少一种金属迹线。