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公开(公告)号：US09913981B1
公开(公告)日：2018-03-13
申请号：US15618751
申请日：2017-06-09
Applicant: OHH-MED MEDICAL LTD.
Inventor： Daniel Lischinsky
IPC: A61N1/36 , A61F5/41 , A61B17/225
CPC classification number: A61N1/36007 , A61B17/2251 , A61B18/00 , A61F5/41 , A61N1/0452 , A61N1/0476 , A61N1/0521 , A61N1/06 , A61N1/36 , A61N1/36034
Abstract: Methods and devices for treating erectile dysfunction are disclosed. Methods are aimed at reducing blood outflow from penile tissue by delivering energy to specific penile tissue that controls blood outflow from the penile tissue and causing remodeling of the specific penile tissue. Devices may be configured to generate RF energy and to apply the generated RF energy to a penis to thereby elevate a temperature of internal penile tissue above a predetermined temperature value while maintaining a penile surface below a predetermined temperature threshold. The predetermined temperature value may be set to initiate synthesis and/or a regeneration of collagen fibers in a collagen-rich penile connective tissue and/or to increase oxygenation of endothelial cells, initiate angiogenesis and neovascularization in a vascular penile tissue. Additionally, electrical penile stimulation is disclosed, possibly applicable in conjuncture with the erectile dysfunction treatment.
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22.发明申请公开(公告)号：US20180049801A1
公开(公告)日：2018-02-22
申请号：US15679225
申请日：2017-08-17
Applicant: Cook Medical Technologies LLC
Inventor： Rune T. Paamand , Per Elgaard
CPC classification number: A61B18/1492 , A61B18/082 , A61B18/20 , A61B2018/00791 , A61B2018/00875 , A61B2018/00994 , A61N1/05 , A61N1/36
Abstract: The present disclosure provides for a device and methods of use to endoluminally heat and/or occlude a body vessel. The method includes a step of contracting the vessel to be treated by a contraction method, such as by delivering an electrical stimulus to induce spasms and decrease the diameter of the vessel. In some embodiments, the electrical stimulus may be a pulsatile electrical stimulus. The device then delivers a heat energy to aid in occlusion of the vessel.
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公开(公告)号：US09895540B2
公开(公告)日：2018-02-20
申请号：US14186236
申请日：2014-02-21
Applicant: Adi Mashiach
Inventor： Adi Mashiach
IPC: A61N1/36 , A61N1/05 , A61N1/372 , A61N1/378 , A61N1/375 , A61B5/11 , A61B5/113 , A61F5/56 , A61N2/00 , A61N2/02 , A61B5/00
CPC classification number: A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
Abstract: A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
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公开(公告)号：US09883813B2
公开(公告)日：2018-02-06
申请号：US15240725
申请日：2016-08-18
Applicant: CARDIOINSIGHT TECHNOLOGIES, INC.
Inventor： Qingguo Zeng , Rémi DuBois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Maria Strom , Brian P. George
IPC: A61B5/044 , A61B5/04 , A61B5/00 , A61B5/0452 , A61N1/36 , A61B5/046 , A61B5/0464 , A61B18/14 , A61B5/0408 , A61B5/042
CPC classification number: A61B5/04012 , A61B5/0044 , A61B5/04085 , A61B5/0422 , A61B5/044 , A61B5/0452 , A61B5/046 , A61B5/0464 , A61B5/486 , A61B5/7264 , A61B18/1492 , A61B2576/023 , A61N1/36
Abstract: A method can determine one or more origins of focal activation. The method can include computing phase for the electrical signals at a plurality of nodes distributed across a geometric surface based on the electrical data across time. The method can determine whether or not a given candidate node of the plurality of nodes is a focal point based on the analyzing the computed phase and magnitude of the given candidate node. A graphical map can be generated to visualize focal points detected on the geometric surface.
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公开(公告)号：US20180028083A1
公开(公告)日：2018-02-01
申请号：US15606216
申请日：2017-05-26
Applicant: Medtronic, Inc.
Inventor： Saul E. GREENHUT , Jian CAO , Xusheng ZHANG
IPC: A61B5/04 , A61B5/024 , A61N1/39 , A61B5/0464 , A61B5/0245
CPC classification number: A61B5/04017 , A61B5/02108 , A61B5/02405 , A61B5/0245 , A61B5/0422 , A61B5/0456 , A61B5/0464 , A61B5/686 , A61B5/7203 , A61B5/7217 , A61B5/7275 , A61N1/025 , A61N1/0504 , A61N1/36 , A61N1/36507 , A61N1/3704 , A61N1/3925 , A61N1/3956 , A61N1/3987
Abstract: A medical device, such as an extra-cardiovascular implantable cardioverter defibrillator (ICD), senses R-waves from a first cardiac electrical signal by a first sensing channel and stores a time segment of a second cardiac electrical signal acquired by a second sensing channel in response to each sensed R-wave. The medical device determines at least one noise parameter from a group of the stored time segments of the second cardiac electrical signal, detects noise based on the noise parameter, and withholds detection of a tachyarrhythmia episode in response to detecting the noise.
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Patent Agency Ranking
公开(公告)号：US20170368355A1
公开(公告)日：2017-12-28
申请号：US15698038
申请日：2017-09-07
Inventor： Jordi Parramon , Rafael Carbunaru , Matt I. Haller
CPC classification number: A61N1/36171 , A61N1/05 , A61N1/0551 , A61N1/36 , A61N1/36071 , A61N1/36125 , A61N1/36175 , A61N1/36178 , A61N1/37235
Abstract: A method for configuring stimulation pulses in an implantable stimulator device having a plurality of electrodes is disclosed, which method is particularly useful in adjusting the electrodes by current steering during initialization of the device. In one aspect, a set of ideal pulses for patient therapy is determined, in which at least two of the ideal pulses are of the same polarity and are intended to be simultaneous applied to corresponding electrodes on the implantable stimulator device during an initial duration. These pulses are reconstructed into fractionalized pulses, each comprised of pulse portions. The fractionalized pulses are applied to the corresponding electrodes on the device during a final duration, but the pulse portions of the fractionalized pulses are not simultaneously applied during the final duration.
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公开(公告)号：US20170368352A9
公开(公告)日：2017-12-28
申请号：US14186236
申请日：2014-02-21
Applicant: Adi Mashiach
Inventor： Adi Mashiach
IPC: A61N1/36 , A61N1/05 , A61N1/372 , A61B5/11 , A61N1/375 , A61F5/56 , A61N2/02 , A61N2/00 , A61N1/378 , A61B5/00 , A61B5/113
CPC classification number: A61N1/36075 , A61B5/0031 , A61B5/11 , A61B5/113 , A61B5/4519 , A61B5/4818 , A61B5/682 , A61B5/6822 , A61B5/6833 , A61B5/6876 , A61B2562/164 , A61F5/566 , A61N1/05 , A61N1/0504 , A61N1/0514 , A61N1/0526 , A61N1/0529 , A61N1/0548 , A61N1/0551 , A61N1/0553 , A61N1/36 , A61N1/36003 , A61N1/3601 , A61N1/3605 , A61N1/36057 , A61N1/3606 , A61N1/3611 , A61N1/36117 , A61N1/36125 , A61N1/36135 , A61N1/36139 , A61N1/36146 , A61N1/37211 , A61N1/37223 , A61N1/37229 , A61N1/37235 , A61N1/37264 , A61N1/3727 , A61N1/3756 , A61N1/3787 , A61N2/006 , A61N2/02 , F04C2270/0421
Abstract: A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
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公开(公告)号：US09833616B2
公开(公告)日：2017-12-05
申请号：US12649197
申请日：2009-12-29
Applicant: Nathan Lee Olson
Inventor： Nathan Lee Olson
CPC classification number: A61N1/056 , A61M25/0013 , A61M25/0032 , A61M25/0054 , A61M25/04 , A61N1/0488 , A61N1/36 , A61N1/3956
Abstract: An implantable medical device (IMD) can include implantable pulse generator (IPG) devices, implantable cardioverter-defibrillators (ICD), cardiac resynchronization therapy defibrillator devices, neurostimulators or combinations thereof. In one example, the IMD can include a body assembly, which can provide at least one electrical signal corresponding to a therapy. The IMD can also include a cardiac lead assembly, which can have a proximal portion and a distal portion. The proximal portion of the cardiac lead assembly can be in communication with the body assembly to receive the therapy and the distal portion can be adapted to be coupled to an anatomical structure to transmit the at least one electrical signal to the anatomical structure. The proximal portion of the cardiac lead assembly can have a first stiffness and the distal portion can have a second stiffness. The first stiffness can be greater than the second stiffness.
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公开(公告)号：US20170333708A1
公开(公告)日：2017-11-23
申请号：US15523914
申请日：2015-11-03
Applicant: GALVANI BIOELECTRONICS LIMITED , FACULDADE DE CIÊNCIAS MÉDICAS DA UNIVERSIDADA NOVA DE LISBOA
Inventor： Silvia Margarida Vilares Santos CONDE , Daniel John CHEW , Hans Jakob Kristoffer FAMM , Maria Pedro Sucena GUARINO , Brad HOLINSKI , Sonal PATEL
CPC classification number: A61N1/3606 , A61B18/12 , A61B2018/00434 , A61N1/05 , A61N1/36
Abstract: The invention refers to a device for inhibiting the neural activity of a carotid sinus nerve (CSN) or carotid body of a subject, the device comprising: one or more transducers configured to apply a signal to the CSN or associated carotid body of the subject, optionally at least two such transducers; and a controller coupled to the one or more transducers, the controller controlling the signal to be applied by the one or more transducers, such that the signal inhibits the neural activity of the CSN or carotid body to produce a physiological response in the subject, wherein the physiological response is one or more of the group consisting of: an increase in insulin sensitivity in the subject, an increase in glucose tolerance in the subject, a decrease in (fasting) plasma glucose concentration in the subject, a reduction in subcutaneous fat content in the subject, and a reduction in obesity in the subject.
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公开(公告)号：US09821003B2
公开(公告)日：2017-11-21
申请号：US15075938
申请日：2016-03-21
Applicant: Palo Alto Investors
Inventor： Anthony Joonkyoo Yun
IPC: A61K31/70 , A61K31/7048 , A61M5/00 , A61B5/145 , A61B5/00 , A61F7/00 , A61H23/00 , A61K31/137 , A61K31/166 , A61K31/21 , A61K31/4468 , A61K31/454 , A61N1/30 , A61N1/36 , A61N1/362 , A61B5/024 , A61B5/11
CPC classification number: A61K31/7048 , A61B5/02405 , A61B5/1116 , A61B5/14521 , A61B5/4035 , A61B5/4238 , A61B5/4266 , A61F7/00 , A61H23/00 , A61K31/137 , A61K31/166 , A61K31/21 , A61K31/4468 , A61K31/454 , A61M5/00 , A61N1/30 , A61N1/36 , A61N1/36007 , A61N1/362
Abstract: Methods and devices treating an autonomic nervous system associated disease condition in a subject are provided. Aspects of the invention include inducing one or more physiological response selected from the group consisting of sweating, gastric emptying, enhanced heart rate variability and enhanced quantitative sensory test responsiveness in a manner sufficient to modify the autonomic nervous system so as to treat the subject for the disease condition. The methods and devices find use in a variety of applications, e.g. in the treatment of subjects suffering from conditions arising from disorders of the autonomic nervous system.
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