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公开(公告)号:US20180095304A1
公开(公告)日:2018-04-05
申请号:US15192811
申请日:2016-06-24
Applicant: QUALCOMM Incorporated
Inventor: Linda Irish , Russell Gruhlke , Manav Raina
CPC classification number: G02F1/113 , G01J3/0289 , G01J3/44 , G01N21/359 , G01N2021/1738 , G01S7/4814 , G01S7/4817 , G01S7/4818 , G02B26/103 , G06F3/0423 , G06T2207/10052
Abstract: Disclosed herein are techniques for determining the position of a light beam on a beam shaping device. A feature can be formed on the beam shaping device to affect at least a portion of a light beam when the feature is illuminated by the light beam. When the light beam is directed onto the feature on the beam shaping device, a feature detection signal may be generated by a detector in response to detecting at least the portion of the light beam affected by the feature that has been illuminated by the light beam. The position of the light beam on the beam shaping device at a time instant can then be determined based, at least in part, on the feature detection signal.
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32.
公开(公告)号:US20180080878A1
公开(公告)日:2018-03-22
申请号:US15578795
申请日:2016-06-02
Inventor: Sam Jin CHOI , Wan Sun Kim , Jae-Ho SHIN , Hun Kuk PARK
IPC: G01N21/65 , G01N33/487 , G01J3/44
CPC classification number: G01N21/658 , B82Y15/00 , B82Y20/00 , B82Y30/00 , G01J3/44 , G01N21/8483 , G01N33/487 , G01N33/54373
Abstract: The present invention relates to: a paper-based surface-enhanced Raman scattering (SERS) substrate comprising metal nanoparticles, which are uniformly distributed and adsorbed on a designed pattern and have a diameter of 1 nm to 100 nm; a point-of-care (POC) diagnostic kit, comprising the paper-based SERS substrate; and a method for preparing the paper-based SERS substrate.
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公开(公告)号:US20180045570A1
公开(公告)日:2018-02-15
申请号:US15552752
申请日:2016-03-08
Applicant: RENISHAW PLC
Inventor: Timothy SMITH , Richard John BLACKWELL-WHITEHEAD
CPC classification number: G01J3/44 , G01J3/06 , G01J2003/064 , G01N21/65 , G01N2201/103 , G01N2201/1045 , G01N2201/1087 , G02B21/002
Abstract: A transmission Raman spectroscopy apparatus has a light source for generating a light profile on a sample, a photodetector having at least one photodetector element, collection optics arranged to collect Raman scattered light transmitted through the sample and direct the Raman light onto the at least one photodetector element and a support for supporting the sample. The support and light source are arranged such that the light profile can be moved relative to the sample in order that the at least one photodetector element receives Raman scattered light generated for different locations of the light profile on the sample.
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公开(公告)号:US09891155B2
公开(公告)日:2018-02-13
申请号:US14545583
申请日:2015-05-26
Applicant: Erik Eising , David A. Prystupa
Inventor: Erik Eising
IPC: G01N15/06 , G01N21/65 , A01B79/00 , G01J3/44 , A01C21/00 , G01N21/3563 , G01N21/552 , G01N15/14 , G01N33/24
CPC classification number: G01N15/06 , A01B79/005 , A01C21/007 , G01J3/44 , G01N15/1434 , G01N15/1459 , G01N21/3563 , G01N21/552 , G01N21/65 , G01N2015/0693 , G01N2033/245
Abstract: A system for measuring soil constituents having coulter comprising an electromagnetic radiation detector, a source of electromagnetic radiation, and a window transparent to electromagnetic radiation, the source emits radiation through said window to the soil, and the detector receives radiation through said window, reflected from the soil. Typically the source is broad band so the detector provides continuous spectra over the range. The source may be quasimonochromatic to provide Raman scattering, which will also provide continuous spectra over the range. These spectra can be subjected to multivariate analysis and compared to spectra of known constituents to identify the presence and concentration of these constituents.
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公开(公告)号:US09891105B2
公开(公告)日:2018-02-13
申请号:US15209843
申请日:2016-07-14
Applicant: Otsuka Electronics Co., Ltd.
Inventor: Hisashi Shiraiwa
CPC classification number: G01J3/28 , G01J3/0208 , G01J3/0218 , G01J3/18 , G01J3/2803 , G01J3/44 , G01J3/4406 , G01N21/6452 , G01N21/6458 , G01N21/65 , G01N2021/6484 , G01N2201/0833 , G01N2201/0846 , G02B21/0032 , G02B21/004 , G02B21/0064
Abstract: A microspectroscope includes: a light source; a plurality of light projecting optical fibers that receive light from the light source; a spectroscope; a plurality of light receiving optical fibers for guiding received light to the spectroscope; and a confocal optical system for causing each of a plurality of beams from the plurality of light projecting optical fibers to be condensed and irradiated onto a sample, and forming images of a plurality of beams from a plurality of condensing points on the sample, respectively on the plurality of light receiving optical fibers.
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公开(公告)号:US20180000406A1
公开(公告)日:2018-01-04
申请号:US15545488
申请日:2016-02-05
Inventor: Hequn Wang , Conor L. Evans , Sam Osseiran , David E. Fisher
CPC classification number: A61B5/443 , A61B5/0075 , A61B5/444 , G01J3/44 , G01N21/8851 , G01N2021/1765 , G01N2021/418 , G01N2021/655
Abstract: A system for visualizing melanin present in tissue can include an imaging system to record a signal based on a presence of melanin in tissue and a display device to display an image based on the signal. A first laser source can emit a Stokes pulse train and a second laser source can emit a pump pulse train. Both the first laser source and the second laser source comprise a tunable center wavelength or frequency. An energy difference between a frequency of the Stokes pulse train and a frequency of the pump pulse train is from 1750 cm−1 to 2250 cm−1. The Stokes and the pump pulse train overlap in space and time. A scanning mechanism focuses the combined Stokes pulse train and pump pulse train within the tissue and scans across the tissue. A detector detects the signal based on a presence of melanin within the tissue.
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37.
公开(公告)号:US09830501B2
公开(公告)日:2017-11-28
申请号:US14339239
申请日:2014-07-23
Applicant: NORTHWESTERN UNIVERSITY
Inventor: Vadim Backman , Hariharan Subramanian , John E. Chandler , Craig White , Jeremy D. Rogers , Lusik Cherkezyan
IPC: G06K9/00 , G02B21/36 , H04N5/235 , H04N5/232 , G01J3/44 , G01J3/12 , G01J3/28 , G02B21/06 , G02B21/16 , G01N21/47
CPC classification number: G06K9/00127 , G01J3/1256 , G01J3/2823 , G01J3/44 , G01N21/47 , G01N2021/4709 , G02B21/06 , G02B21/16 , G02B21/365 , H04N5/23212 , H04N5/2354
Abstract: The present technology provides methods, systems, and apparatuses to achieve high throughput and high speed acquisition of partial wave spectroscopic (PWS) microscopic images. In particular, provided herein are high-throughput, automated partial wave spectroscopy (HT/A-PWS) instruments and systems capable of rapid acquisition of PWS Microscopic images and clinical, diagnostic, and research applications thereof.
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公开(公告)号:US09778105B2
公开(公告)日:2017-10-03
申请号:US14518588
申请日:2014-10-20
Applicant: WAYNE STATE UNIVERSITY
Inventor: Gregory W. Auner , Changhe Huang , Christopher M. Thrush , Michelle Brusatori
CPC classification number: G01J3/021 , G01J3/18 , G01J3/44 , G01J3/4412 , G01J3/45 , G01J3/4531 , G01J3/4532 , G02B5/1861
Abstract: An apparatus for performing Raman spectral analysis of a sample is described, comprising a coherent light source, an first optical chain to direct the coherent light to impinge on the sample, a second optical chain to direct the scattered light onto a diffraction grating, and a third optical chain to direct the diffracted light onto detection array. The diffraction grating is a stairstep with a metalized surface, and a plurality of metalized stripes on a flat surface is disposed in a direction orthogonal to the long dimension of the stairsteps. The region between the flat surface and the stairstep is transparent. The zeroth-order fringe is selected by a slit and directed onto camera. The resultant interferogram is Fourier transformed to produce a representation of the Raman spectrum.
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公开(公告)号:US20170268977A1
公开(公告)日:2017-09-21
申请号:US14912852
申请日:2014-04-08
Applicant: Antonio Ph.D. GARCIA , Luis NUNEZ , Mujica VLADIMIRO
Inventor: Antonio A. GARCIA , Luis NUNEZ , VLADIMIRO MUJICA
IPC: G01N15/02 , G01N33/543 , G01N33/553 , G01N33/569
CPC classification number: G01N15/0205 , G01B11/24 , G01J3/0205 , G01J3/44 , G01M11/37 , G01N33/54346 , G01N33/553 , G01N33/56983 , G01N2015/0065 , G01N2021/8835 , G01N2333/185 , G02B6/262
Abstract: An apparatus for particle size and a distribution of a population of particle measurements, comprising: a non-monochromatic light source that emits a plurality of a non-monochromatic rays, a medium that includes a particle, wherein the medium is a liquid phase and the particle is suspended within the medium to form a particle-suspension, a droplet of the particle-suspension wherein the droplet is provided with a curved surface, and a detector that is provided with a light providing element.
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公开(公告)号:US09733125B2
公开(公告)日:2017-08-15
申请号:US14431080
申请日:2013-09-25
Applicant: The Penn State Research Foundation , Washington University
Inventor: Zhiwen Liu , Lan Yang , Perry Edwards , Corey Janisch , Bo Peng , Sahin Ozdemir
CPC classification number: G01J3/44 , G01J3/0208 , G01J3/0224 , G01J3/10 , G01J3/26 , G01J3/2823 , G01N21/65
Abstract: Embodiments of the invention provide Raman spectroscopy methods and devices that exploit high quality factor (Q) resonators to enhance Raman signal by several orders of magnitude over the signal typically expected for Raman methods. Embodiments typically include one or more resonators, typically microtoroid microresonators. Embodiments also take advantage of Rayleigh scattering using these microresonators. Embodiments may be particularly useful for non-labeled nanoparticle sensing.
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