中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

486 records (took 0.066 seconds)

    Membrane transfer method and tool
    52.
    发明授权
    Membrane transfer method and tool 有权

    公开(公告)号：US09732371B2

    公开(公告)日：2017-08-15

    申请号：US14036339

    申请日：2013-09-25

    Applicant: EMD Millipore Corporation

    Inventor： Gael Waiche ,  Monika Kukuczka

    IPC: C12Q1/24 ,  C12M1/30 ,  C12M1/26

    CPC classification number: C12Q1/24 ,  C12M33/02 ,  C12M33/14

    Abstract: A method for transferring a filter membrane (130) bearing a retentate to a reagent pad (310), in which the membrane is mounted in a support frame (120) having a shoulder (121) and a skirt (122) projecting from the shoulder, the pad being mounted on a cassette (300) of complementary form to said skirt, the skirt being adapted to slide sealingly on the cassette until it comes into abutment formed by the shoulder, the method comprising the steps of sealingly engaging the skirt of the membrane support frame on the cassette, establishing a pressure difference between the cassette and the membrane support frame such that the membrane adopts the shape of a dome pointing towards the pad, while maintaining the pressure difference, applying a force on the frame so as to make the skirt slide on the cassette until contact is established between the end of the dome and the pad, maintaining a force on the frame so as to move it downward until it comes into abutment formed by the shoulder while maintaining the pressure difference.

    Enhanced Aerosol Test For Assessing Filter Integrity
    54.
    发明申请
    Enhanced Aerosol Test For Assessing Filter Integrity 审中-公开
    用于评估过滤器完整性的增强型气溶胶测试

    公开(公告)号：US20160299048A1

    公开(公告)日：2016-10-13

    申请号：US15057641

    申请日：2016-03-01

    Applicant: EMD Millipore Corporation

    Inventor： Salvatore Giglia ,  David Nhiem ,  Gabriel Tkacik

    IPC: G01N15/08

    CPC classification number: G01N15/088 ,  B01D65/102 ,  B01D2273/18 ,  G01M3/20 ,  G01N15/0826 ,  G01N2015/084 ,  G01N2015/0846

    Abstract: A method of aerosol integrity testing of filters, capable of detecting single defects that are less than 20 μm in diameter, and even as small as 2 μm in diameter, in liquid sterilizing grade filters such as filter cartridges. The method challenges the filter in a dry state with a particle stream of aerosol particles of the appropriate size and in the appropriate concentration, such that at least one or more of the particles in the stream will penetrate a defective region or regions within the membrane but will not penetrate in the integral region of the membrane. Wetting of the filter is not required.

    Abstract translation: 一种过滤器的气溶胶完整性测试方法，能够检测液体杀菌级过滤器（如过滤器滤芯）中直径小于20μm，直径小至2μm的单一缺陷。 该方法在干燥状态下用适当尺寸和适当浓度的气溶胶颗粒的颗粒流挑战过滤器，使得流中的至少一种或多种颗粒将渗透膜内的缺陷区域或区域，但 不会渗入膜的整体区域。 不需要过滤器的润湿。

    Chromatography apparatus and method
    57.
    发明授权
    Chromatography apparatus and method 有权
    色谱仪和方法

    公开(公告)号：US09429502B2

    公开(公告)日：2016-08-30

    申请号：US14109988

    申请日：2013-12-18

    Applicant: EMD Millipore Corporation

    Inventor： Chris Scott ,  Rob Colonna ,  Christopher Barmore ,  Todd Taylor ,  Daniel Morgan

    IPC: G01N1/28 ,  G01N1/40 ,  G01N30/14 ,  B01J20/281 ,  B01D61/18 ,  B01L3/00

    CPC classification number: G01N1/28 ,  B01D61/18 ,  B01J20/281 ,  B01L3/50255 ,  G01N1/4077 ,  G01N30/14 ,  G01N2030/146

    Abstract: Sample preparation device for receiving in sealing relation one or more filter assemblies and one or more sample containers, each container uniquely positioned within the device to receive filtered sample from a designated filter. The device includes a body, a lid disposed on the body, a container tray, a base, an integrated seal on the body, a valve and a valve actuator. The tray can be disposed in a vacuum chamber defined by the lid and the body, and one or more sample containers can be disposed in the tray. When properly positioned in the tray in the vacuum chamber, each container is in fluid communication with a single respective filter assembly disposed in sealing relation in a respective aperture in the lid. A single actuation of a valve to place the vacuum chamber under vacuum causes the lid to seal to the base and drives the simultaneous filtration of a plurality of samples.

    Abstract translation: 用于以密封关系接收一个或多个过滤器组件和一个或多个样品容器的样品制备装置，每个容器唯一地定位在装置内以从指定的过滤器接收经过滤的样品。 该装置包括主体，设置在主体上的盖，容器托盘，基座，主体上的集成密封件，阀和阀致动器。 托盘可以设置在由盖和主体限定的真空室中，并且一个或多个样品容器可以设置在托盘中。 当适当地定位在真空室中的托盘中时，每个容器与在盖中的相应孔中以密封关系设置的单个相应的过滤器组件流体连通。 将真空室置于真空下的阀的单次致动导致盖子密封到基座并驱动多个样品的同时过滤。

    Immunoassay Product And Process
    60.
    发明申请
    Immunoassay Product And Process 有权
    免疫测定产品和方法

    公开(公告)号：US20160178625A1

    公开(公告)日：2016-06-23

    申请号：US15006153

    申请日：2016-01-26

    Applicant: EMD Millipore Corporation

    Inventor： Chris Scott ,  Phillip Clark ,  Kurt E. Greenizen ,  Ryan A. Amara ,  Robert Colonna

    IPC: G01N33/558 ,  B01L9/00 ,  B01L3/00

    CPC classification number: G01N33/558 ,  B01J20/28033 ,  B01J20/28035 ,  B01J20/2804 ,  B01L3/5023 ,  B01L9/52 ,  B01L2200/025 ,  B01L2300/0609 ,  B01L2300/0681 ,  B01L2300/069 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/126 ,  B01L2400/0487 ,  B01L2400/049 ,  G01N33/54366 ,  G01N33/56911 ,  G01N2469/10 ,  G01N2469/20

    Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

    Abstract translation: 本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。 该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许 降低这种液体的起始体积。 优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。 分配器和支撑件保持在一起以在膜周围形成一个信封。 在这样做时优选使用铰链，夹子和其它这样的装置。

Patent Agency Ranking