摘要:
The present invention relates to isolated polypeptides which comprise an amino acid sequence consisting of a mutated functional Abl kinase domain, said mutated functional kinase domain being resistant to inhibition of its tyrosine kinase activity by N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-4-(4-methyl-piperazin-1 -ylmethyl)-benzamide or a salt thereof, to the use of such polypeptides to screen for compounds which inhibit the tyrosine kinase activity of such polypeptides, to nucleic acid molecules encoding such polypeptides, to recombinant vectors and host cells comprising such nucleic acid molecules and to the use of such nucleic acid molecules in the production of such polypeptides for use in screening for compounds which inhibit the tyrosine kinase activity of such polypeptides.
摘要:
A system and method for controlling an engine involves providing a pumping torque estimation model. The model distinguishes between pumping losses due to throttling and pumping losses due to valve flow losses. The model is implemented by a pair of look-up tables. The data in each look-up table reflect Pumping Mean Effective Pressure (PMEP), which is indicative of the pumping work. The throttling loss table provides a first contribution based on an engine delta pressure. The valve flow loss table provides a second contribution based on an engine speed and a relative airload. The first and second contributions are summed and then multiplied by a predetermined factor to convert the pumping work (PMEP) into pumping torque. The model will work with naturally-aspirated, turbo-charged and super-charged air induction configurations and provides improved altitude compensation. The model will also work with both spark-ignition and compression-ignition configurations.
摘要:
The present invention relates to a composition comprising thermoplastic materials and crosslinked microgels which are not crosslinked by high-energy radiation, processes for its preparation, its use for the production of thermoplastically processable shaped articles and shaped articles produced from the composition.
摘要:
A semiconductor laser comprising a laser-active layer sequence (1) having a first main face (1003), on which is arranged a heat conducting layer (3) containing carbon nanotubes (30) and a method for producing such a semiconductor laser.
摘要:
The present invention relates to luminescent SiOz, flakes, especially porous luminescent SiOz flakes, wherein 0.70≦z≦2.0, especially 0.95≦z≦2.0, comprising an organic, or inorganic luminescent compound, or composition, which can provide enhanced (long term) luminescent efficacy.
摘要:
A surface emitting semiconductor component (1) with an emission direction is disclosed, which comprises a semiconductor body (2). The semiconductor body comprises a plurality of active regions (4a, 4b) which are suitable for the generation of radiation and are spaced apart from one another, wherein between two active regions a tunnel junction (5) is monolithically integrated in the semiconductor body. The two active regions are electrically conductively connected by means of the tunnel junction, and the semiconductor component is provided for operation with an external resonator. A laser device comprising a semiconductor component of this type and an external resonator is also disclosed.
摘要:
A surface emitting semiconductor component (1) with an emission direction which comprises a semiconductor body (2). The semiconductor body comprises a plurality of active regions (4a, 4b) which are suitable for the generation of radiation and are arranged in a manner spaced apart from one another, a frequency-selective element (6) being formed in the semiconductor body.
摘要:
The invention relates to a planar structure having an ultraphobic surface and at least one hydrophilic and/or oleophilic area that, in addition to being hydrophilic and/or oleophilic, has at least one additional functionality. The invention also relates to a method for producing the inventive planar structure and to the use thereof.
摘要:
The present invention relates to laser diodes with single mode emission at high output powers, as well as to structures and processes facilitating simple manufacture of such a devices. The invention includes a semiconductor laser (10) with a semiconductor substrate (11), a laser layer (13) arranged on the semiconductor substrate, an array of waveguide ridges (18) arranged at a distance from the laser layer, and several strip-shaped lattice structures (23) arranged on the flat surface between the waveguide ridges. The lattice structure (23) is formed on an insulating or barrier layer (26) at a distance from the laser layer above the laser layer (13). Processes for the production of such a semiconductor laser are also disclosed.
摘要:
A method of improving the operating characteristics of an internal combustion engine equipped with electronic throttle control employs variable cam timing to vary the phasing of the intake valves and/or exhaust valves so as to achieve lower feed gas emissions and improved fuel economy while delivering as closely as possible the desired torque. The method can be implemented using a fuel-lead strategy or an air-lead strategy. Whenever a change is requested in the amount of torque, the method responds by adjusting the amount of fuel flow, the spark timing, the position of the throttle and/or the positions of the intake valves and/or the exhaust valves so as to deliver the desired torque. The method adjusts those operating parameters in a way that improves the ability of the engine to deliver the desired torque, produce less feed gas emissions, idle more stably, and consume less fuel.