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    High throughput multi-dimensional sample analysis
    1.
    发明授权
    High throughput multi-dimensional sample analysis 有权
    高通量多维样本分析

    公开(公告)号：US07132650B1

    公开(公告)日：2006-11-07

    申请号：US10951255

    申请日：2004-09-25

    申请人： Ronald C. Gamble ,  Stephen D. O'Connor ,  Bruce Wilcox ,  Matthew M. Gregori

    发明人： Ronald C. Gamble ,  Stephen D. O'Connor ,  Bruce Wilcox ,  Matthew M. Gregori

    IPC分类号： H01J49/42

    CPC分类号： G01N30/7233 ,  G01N30/466 ,  G01N30/80 ,  G01N2030/8447 ,  H01J49/0018 ,  H01J49/0431 ,  H01J49/107 ,  Y10T137/86863 ,  Y10T137/86871 ,  Y10T436/115831

    摘要： High throughput analytical systems and methods employing multiple liquid phase separation process regions coupled to a common mass spectrometer are provided. Disclosed systems and methods permits parallel separation and parallel storage of discrete eluate fractions, followed by sequential discharge and ionization of previously stored eluate portions to yield a composite ion stream containing the sequential series of eluate portions, followed by mass analysis of the ion stream. A common manifold may receive ions and utilize pressurized gas or ion gating to direct ions within the manifold toward the mass spectrometer inlet.

    摘要翻译： 提供了使用耦合到共同的质谱仪的多个液相分离工艺区域的高通量分析系统和方法。 公开的系统和方法允许离散洗脱液级分的并行分离和平行存储，随后顺序地排出和离子化先前储存的洗脱液部分，以产生含有顺序一系列洗脱液部分的复合离子流，随后对离子流进行质量分析。 常见的歧管可以接收离子并利用加压气体或离子门控来将歧管内的离子引向质谱仪入口。

    SYSTEMS AND METHODS FOR MANAGING UTILITY CONSUMPTION
    3.
    发明申请
    SYSTEMS AND METHODS FOR MANAGING UTILITY CONSUMPTION 审中-公开
    用于管理实用消费的系统和方法

    公开(公告)号：US20110178610A1

    公开(公告)日：2011-07-21

    申请号：US13120920

    申请日：2009-10-15

    申请人： Stephen D. O'Connor ,  Ronald C. Gamble ,  Richard A. Suchter

    发明人： Stephen D. O'Connor ,  Ronald C. Gamble ,  Richard A. Suchter

    IPC分类号： G05B13/04 ,  G06G7/48

    CPC分类号： G06Q10/06

    摘要： A system and method for monitoring and managing utility consumption includes use of (A) one or more sensors arranged to monitor an operating condition and/or utility consumption of at least one segment or appliance of a first facility; (B) a memory including at least one of (i) stored utility consumption information correlated or normalized to at least one designated parameter affecting utility consumption or (ii) hypothetical utility consumption; (C) a processor to compare the monitored information with the stored information, and (D) an output medium to store and/or display the comparison information. Stored consumption information may relate to the first facility or a second facility. Hypothetical utility consumption information may relate to a segment or appliance of the first facility operated according to optimized conditions, or an upgraded segment or appliance.

    摘要翻译： 一种用于监测和管理公用事业消耗的系统和方法包括使用（A）布置成监测第一设施的至少一个段或设备的运行状况和/或公用事业消耗的一个或多个传感器; （B）存储器，其包括以下至少一个：（i）存储的与至少一个影响公用事业消耗的指定参数相关或归一化的公用消费信息;（ii）假设的公用事业消费; （C）处理器，用于将所监视的信息与存储的信息进行比较，以及（D）存储和/或显示比较信息的输出介质。 存储的消费信息可能与第一设施或第二设施有关。 假设效用消耗信息可以涉及根据优化条件操作的第一设施的段或设备，或升级的段或设备。

    High throughput systems and methods for parallel sample analysis
    4.
    发明授权
    High throughput systems and methods for parallel sample analysis 有权
    高通量系统和并行样本分析方法

    公开(公告)号：US06987263B2

    公开(公告)日：2006-01-17

    申请号：US10736154

    申请日：2003-12-13

    申请人： Steven E. Hobbs ,  Stephen D. O'Connor ,  Ronald C. Gamble

    发明人： Steven E. Hobbs ,  Stephen D. O'Connor ,  Ronald C. Gamble

    IPC分类号： B01D54/44 ,  H01J49/00

    CPC分类号： G01N30/6043 ,  B01L3/5027 ,  G01N30/6095 ,  G01N30/72 ,  H01J49/009 ,  H01J49/04

    摘要： Systems for analyzing multiple samples in parallel using mass spectrometric preferably coupled with fluid phase separation techniques are provided. A multi-analyzer mass spectrometer includes multiple inlets, multiple mass analyzers, and multiple transducers to conduct mass analyses of multiple samples in parallel. A modular mass analyzer may include a vacuum enclosure, a chassis, and multiple mass analysis modules disposed within the chassis. Modules are preferably disposed in a spatially compact two-dimensional array. A common multi-stage vacuum system may be utilized in conjunction with baffles or partitions disposed within and between modules to maintain differential vacuum conditions within the spectrometer utilizing a minimum number of pumps. Common control inputs may be provided to multiple modules or other components within a multi-analyzer spectrometer. Fluid phase separation devices for use with a multi-analyzer spectrometer may be microfluidic devices utilizing chromatographic, electrophoretic, or other separation methods.

    摘要翻译： 提供了使用优选与流体相分离技术耦合的质谱分析多个样品的系统。 多分析仪质谱仪包括多个入口，多个质量分析仪和多个换能器，用于并行进行多个样品的质量分析。 模块化质量分析器可以包括真空外壳，底盘以及设置在底盘内的多个质量分析模块。 模块优选地设置在空间紧凑的二维阵列中。 共同的多级真空系统可以与设置在模块内和模块之间的挡板或隔板一起使用，以利用最少数量的泵来保持光谱仪内的差分真空条件。 通常的控制输入可以提供给多分析仪光谱仪中的多个模块或其他组件。 用于多分析仪光谱仪的流体相分离装置可以是利用色谱，电泳或其它分离方法的微流体装置。