Hourglass-shaped cavitation chamber with spherical lobes
    3.
    发明申请
    Hourglass-shaped cavitation chamber with spherical lobes 审中-公开
    具有球形裂纹的沙漏形空化室

    公开(公告)号:US20060269459A1

    公开(公告)日:2006-11-30

    申请号:US11149822

    申请日:2005-06-09

    Abstract: An hourglass-shaped cavitation chamber is provided. The chamber is comprised of two large spherical regions separated by a smaller cylindrical region. Coupling the regions are two transitional sections which are preferably smooth and curved. The chamber can be fabricated from either a fragile material, such as a glass, or a machinable material, such as a metal. An acoustic driver assembly is coupled to one end of the cavitation chamber, preferably using a threaded means (e.g., bolt or all-thread/nut), an epoxy joint, a diffusion bond joint, or a braze joint. If desired, a second acoustic driver assembly can be coupled to the second chamber end. Preferably the driver or drivers are attached such that their central axis is coaxial with the central axis of the cavitation chamber. Coupling conduits which can be used to fill/drain the chamber as well as couple the chamber to a degassing and/or circulatory system can be attached to one, or both, ends of the chamber. When used, preferably the conduit or conduits are attached off-axis.

    Abstract translation: 设有沙漏形的气蚀室。 该腔室由两个由较小圆柱形区域隔开的大球形区域组成。 耦合这些区域是两个过渡部分,其优选是平滑和弯曲的。 该室可以由易碎材料(例如玻璃)或可机加工的材料(例如金属)制成。 声学驱动器组件联接到气蚀室的一端,优选地使用螺纹装置(例如螺栓或全螺纹/螺母),环氧接头,扩散接合接头或钎焊接头。 如果需要,第二声学驱动器组件可以联接到第二腔室端。 优选地,驱动器或驱动器被附接成使得其中心轴线与空化室的中心轴线同轴。 可用于填充/排出腔室以及将腔室连接到脱气和/或循环系统的耦合管道可附接到腔室的一端或两端。 当使用时,优选地将导管或导管偏离轴附接。

    Hourglass-shaped cavitation chamber
    4.
    发明申请
    Hourglass-shaped cavitation chamber 审中-公开
    沙漏形气穴室

    公开(公告)号:US20060269457A1

    公开(公告)日:2006-11-30

    申请号:US11147728

    申请日:2005-06-08

    Abstract: An hourglass-shaped cavitation chamber is provided. The chamber is comprised of two large cylindrical regions separated by a smaller cylindrical region. Coupling the regions are two transitional sections which are preferably smooth and curved. The chamber can be fabricated from either a fragile material, such as a glass, or a machinable material, such as a metal. A ring-shaped acoustic driver is positioned around the outer circumference of one of the two large cylindrical regions of the cavitation chamber. Preferably the driver is held in place with an epoxy or other adhesive. If desired, a second ring-shaped acoustic driver can be positioned around the outer circumference of the second of the two large cylindrical regions of the cavitation chamber. Coupling conduits which can be used to fill/drain the chamber as well as couple the chamber to a degassing and/or circulatory system can be attached to one, or both, ends of the chamber.

    Abstract translation: 设有沙漏形的气蚀室。 该腔室由两个较大圆柱形区域组成,两个较大的圆柱形区域由较小的圆柱形区域 耦合这些区域是两个过渡部分,其优选是平滑和弯曲的。 该室可以由易碎材料(例如玻璃)或可机加工的材料(例如金属)制成。 围绕空化室的两个大圆柱形区域之一的外圆周围设置环形声学驱动器。 优选地,驱动器用环氧树脂或其它粘合剂保持就位。 如果需要,第二环形声学驱动器可以围绕空化室的两个大圆柱形区域中的第二个的外周定位。 可用于填充/排出腔室以及将腔室连接到脱气和/或循环系统的耦合管道可附接到腔室的一端或两端。

    Hourglass-shaped cavitation chamber
    5.
    发明申请
    Hourglass-shaped cavitation chamber 审中-公开
    沙漏形气穴室

    公开(公告)号:US20060269429A1

    公开(公告)日:2006-11-30

    申请号:US11147943

    申请日:2005-06-08

    Abstract: An hourglass-shaped cavitation chamber is provided. The chamber is comprised of two large cylindrical regions separated by a smaller cylindrical region. Coupling the regions are two transitional sections which are preferably smooth and curved. Although the chamber is preferably fabricated from a machinable material, such as a metal, it can also be fabricated from a fragile material, such as a glass. An acoustic driver assembly is incorporated within the chamber wall at one end of the cavitation chamber. The driver can be threadably coupled to the chamber or attached using an epoxy, diffusion bonding, brazing or welding. O-rings or other seals can be used to seal the driver to the chamber. The head surface of the driver assembly can be flush, recessed, or extended from the internal chamber surface. The head surface of the driver assembly can be flat or shaped. If desired, a second acoustic driver assembly can be incorporated within the chamber wall at the other end of the cavitation chamber. Preferably the driver or drivers are attached such that their central axis is coaxial with the central axis of the cavitation chamber. Coupling conduits which can be used to fill/drain the chamber as well as couple the chamber to a degassing and/or circulatory system can be attached to one, or both, ends of the chamber. When used, preferably the conduit or conduits are attached off-axis.

    Abstract translation: 设有沙漏形的气蚀室。 该腔室由两个较大圆柱形区域组成,两个较大的圆柱形区域由较小的圆柱形区域 耦合这些区域是两个过渡部分,其优选是平滑和弯曲的。 虽然腔室优选地由诸如金属的可加工材料制成,但是其也可以由诸如玻璃之类的脆性材料制成。 声学驱动器组件结合在空腔的一端的腔室壁内。 驱动器可以螺纹连接到腔室或使用环氧树脂,扩散接合,钎焊或焊接连接。 O形圈或其他密封件可用于将驱动器密封到腔室。 驱动器组件的头表面可以与内腔表面齐平,凹入或延伸。 驱动器组件的头表面可以是平的或成形的。 如果需要,第二声驱动器组件可以并入空腔的另一端的腔壁内。 优选地,驱动器或驱动器被附接成使得其中心轴线与空化室的中心轴线同轴。 可用于填充/排出腔室以及将腔室连接到脱气和/或循环系统的耦合管道可附接到腔室的一端或两端。 当使用时,优选地将导管或导管偏离轴附接。

    Methods for reducing the formation of by-products in the production of recombinant polypepticles
    6.
    发明申请
    Methods for reducing the formation of by-products in the production of recombinant polypepticles 有权
    减少重组多肽生产中副产物形成的方法

    公开(公告)号:US20040101449A1

    公开(公告)日:2004-05-27

    申请号:US10303452

    申请日:2002-11-25

    Abstract: An apparatus for the countercurrent contacting of a gas and downflowing solid particles includes a housing and a plurality of baffles positioned within the housing. The baffles are arranged in at least first and second vertically spaced levels in successively lower position, each of the first and second levels including a row of at least two baffles oriented parallel to one another and inclined from horizontal so as to facilitate movement of the solid particles and provide the maximum area for flow. Baffles are oriented so as to laterally shift the direction of downflowing particles transversely as the particles move from one level to the next lower level and avoid channeling of the phases. The number of baffles, length and spacing is optimized to provide maximum interfacial area for interaction between the phases.

    Abstract translation: 用于气体和向下流动的固体颗粒的逆流接触的装置包括壳体和定位在壳体内的多个挡板。 挡板布置在连续下位置的至少第一和第二垂直间隔的水平面上,第一和第二水平面中的每一个包括一排至少两个彼此平行且从水平方向倾斜的挡板,以便于固体 颗粒并提供流量的最大面积。 挡板被定向为当颗粒从一个水平移动到下一个较低水平时横向地横向移动向下流动的颗粒的方向,并且避免相的通道。 挡板的数量,长度和间距被优化,以提供相间相互作用的最大界面面积。

    HYDRATION APPARATUS AND METHOD
    9.
    发明申请
    HYDRATION APPARATUS AND METHOD 有权
    水化装置和方法

    公开(公告)号:US20160129418A1

    公开(公告)日:2016-05-12

    申请号:US14536415

    申请日:2014-11-07

    Abstract: Vessels including an enclosure having an outer perimeter and an interior space, a channel disposed in the interior space, a first port disposed on a surface of the first enclosure at or proximate to a first end of the channel, and a second port disposed on a surface of the first enclosure at or proximate to a second end of the channel, where the channel has a length greater than the shortest distance between the first port and the second port, and where the first port and the second port are in fluid communication with one another. In some cases, the length of the channel is greater than a length of the outer perimeter. Optionally, the vessel may have a second enclosure having an outer perimeter and an interior space with a second channel disposed in the interior space, a third port disposed on a surface of the second enclosure at or proximate to a first end of the second channel, and a fourth port disposed on a surface of the second enclosure at or proximate to a second end of the second channel, where the second port, the third port and fourth port are in fluid communication. In yet some other optional variations, the vessel further includes a plurality of enclosures each having an outer perimeter and an interior space, a channel disposed in the interior space, a port disposed on a surface of the enclosure at or proximate to a first end of the channel, and a port disposed on a surface of the enclosure at or proximate to a second end of the channel, where the channel has a length greater than a shortest distance between the ports, and the second port and the ports disposed on the surface of the plurality of enclosures are in fluid communication. The perimeter shape of the enclosure(s) may be any suitable shape, including, but not limited to, substantially circular, ovate or rectangular.

    Abstract translation: 包括具有外周边和内部空间的外壳的容器,设置在内部空间中的通道,设置在第一外壳的表面上的第一端口或位于通道的第一端附近的第一端口,以及设置在第一端口上的第二端口 第一外壳的表面在通道的第二端处或附近,其中通道具有大于第一端口和第二端口之间的最短距离的长度,并且其中第一端口和第二端口与第一端口和第二端口流体连通 另一个。 在一些情况下,通道的长度大于外周长。 可选地,容器可以具有第二外壳,其具有外周边和内部空间,第二通道设置在内部空间中;第三端口,设置在第二外壳的表面上或靠近第二通道的第一端, 以及第四端口,所述第四端口设置在所述第二壳体的表面上或者靠近所述第二通道的第二端,其中所述第二端口,所述第三端口和第四端口处于流体连通状态。 在还有一些可选的变型中,容器还包括多个外壳,每个外壳具有外周边和内部空间,设置在内部空间中的通道,设置在壳体的表面上或靠近第一端的端口 所述通道和设置在所述外壳的表面上的端口处于或接近所述通道的第二端,其中所述通道的长度大于所述端口之间的最短距离,并且所述第二端口和设置在所述表面上的所述端口 多个外壳的流体连通。 外壳的周边形状可以是任何合适的形状,包括但不限于基本圆形,卵形或矩形。

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