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    Liquid applicator and liquid supply method to be used in liquid applicator
    114.
    发明申请
    Liquid applicator and liquid supply method to be used in liquid applicator 失效
    液体涂抹器和液体供应方法用于液体涂抹器

    公开(公告)号：US20040219689A1

    公开(公告)日：2004-11-04

    申请号：US10772361

    申请日：2004-02-06

    申请人： Canon Kabushiki Kaisha

    发明人： Tsunenori Soma

    IPC分类号： G01N001/10

    CPC分类号： G01N35/00663 ,  B01J2219/0036 ,  B01J2219/00378 ,  C40B60/14 ,  G01N35/1072 ,  G01N35/1074 ,  G01N2035/00673

    摘要： A liquid applicator suitable for manufacturing probe arrays comprises a liquid ejection section having a plurality of sets of a liquid ejecting nozzle adapted to eject liquid onto a medium, a liquid containing section communicating with the liquid ejecting nozzle and a supply port for supplying liquid to the liquid containing section, a liquid supply section having a liquid supply member arranged therein to store liquid to be applied and adapted to supply liquid to the liquid ejection section by way of the supply ports, an information recording body arranged at the liquid ejection section and/or the liquid supply member of the liquid supply section and an information reading device adapted to read information recorded in the information recording body.

    摘要翻译： 适用于制造探针阵列的液体涂布器包括：液体喷射部分，具有多组液体喷射喷嘴，用于将液体喷射到介质上;液体容纳部分，与液体喷射喷嘴连通;以及供给口，用于向 液体供应部分，其具有布置在其中的液体供应部件，用于存储待施加的液体，并且适于通过供给口向液体喷射部分供给液体;信息记录体，布置在液体喷射部分和/ 或液体供应部分的液体供给部件和适于读取记录在信息记录体中的信息的信息读取装置。

    Polymer synthesizer
    117.
    发明授权
    Polymer synthesizer 失效
    聚合物合成仪

    公开(公告)号：US06800250B1

    公开(公告)日：2004-10-05

    申请号：US09527106

    申请日：2000-03-16

    申请人： Scott P. Hunicke-Smith ,  Robert Guettler ,  Jimmy Tiansing Koh

    发明人： Scott P. Hunicke-Smith ,  Robert Guettler ,  Jimmy Tiansing Koh

    IPC分类号： B01J1900

    CPC分类号： B01J19/0046 ,  B01J2219/00286 ,  B01J2219/00313 ,  B01J2219/00315 ,  B01J2219/00333 ,  B01J2219/0036 ,  B01J2219/00394 ,  B01J2219/00414 ,  B01J2219/00418 ,  B01J2219/00423 ,  B01J2219/005 ,  B01J2219/00585 ,  B01J2219/0059 ,  B01J2219/00596 ,  B01J2219/00689 ,  B01J2219/00691 ,  B01J2219/00722 ,  C40B40/06 ,  C40B60/14 ,  Y10T436/11 ,  Y10T436/110833 ,  Y10T436/112499 ,  Y10T436/113332

    摘要： A polymer synthesizer is disclosed which has a base on which sits a synthesis case, a synthesis block, and a means of moving the synthesis block and supports for a reagent shelf. The synthesis case has a loading station, drain station, and a water tolerant reagent area and a water sensitive reagent dispensing area. The synthesis case has a cover, a first and a second side, a first and a second end, and a bottom side which contacts the base. The bottom side of the synthesis case has a top face in which there are tracks. A synthesis block moves back and forth in the synthesis case and has a top face and an opening in the top face for a synthesis plate with a plurality of wells. The synthesis block also has a collection area under the synthesis plate to drain spent reagents or optionally hold a sample plate. The polymer synthesizer also has a means of moving the synthesis block back and forth in the synthesis case, preferably a pulley, cable and motor. The polymer synthesizer also has a means of draining the liquid from the synthesis plate. A method of synthesizing oligonucleotides with the polymer synthesizer also is disclosed.

    摘要翻译： 公开了一种聚合物合成器，其具有位于其上的基座，合成块，以及移动合成块并支持试剂架的装置。 合成箱具有装载站，排水站和耐水试剂区域和水敏试剂分配区域。 合成箱具有盖，第一和第二侧，第一和第二端以及与底部接触的底侧。 合成箱的底部有一个顶面，其中有轨道。 合成块在合成情况下来回移动，并且在具有多个孔的合成板的顶面中具有顶面和开口。 合成块还具有合成板下的收集区域以排出废试剂或任选地保持样品板。 聚合物合成器还具有在合成情况下来回移动合成块的装置，优选滑轮，电缆和马达。 聚合物合成仪还具有从合成板排出液体的方法。 还公开了与聚合物合成仪合成寡核苷酸的方法。

    Method and device for dosing fluid media
    118.
    发明申请
    Method and device for dosing fluid media 审中-公开
    计量流体介质的方法和装置

    公开(公告)号：US20040185167A1

    公开(公告)日：2004-09-23

    申请号：US10481076

    申请日：2003-12-16

    发明人： Heiko Zimmermann ,  Rolf Hagerdorn ,  Gunter Fuhr

    IPC分类号： B05D003/00 ,  B01L003/02

    CPC分类号： B01L3/0268 ,  B01J2219/0036 ,  B01J2219/0043 ,  C40B60/14

    摘要： A dosing method, particularly for microdosing fluid media, is described, in which at least one drop (11) is generated using a drop generator (10) and moved on a free flight path (12) which is directed toward a target (30), the drop (11) being incident on a masking device (20) having at least one structure element (21-28), which projects into the flight path (12) and on which at least one partial drop (13, 15-18) is detached from the drop (11), and the at least one partial drop is transferred onto the target. A dosing device for performing the method is also described.

    摘要翻译： 描述了一种特别用于微量流体介质的计量方法，其中使用液滴发生器（10）产生至少一个液滴（11）并且在朝向目标（30）的自由飞行路径（12）上移动， ，所述液滴（11）入射到具有至少一个结构元件（21-28）的掩蔽装置（20）上，所述至少一个结构元件（21-28）突出到所述飞行路径（12）中，并且其上至少一个部分液滴（13,15-18 ）与液滴（11）分离，并且将至少一个部分液滴转印到靶上。 还描述了用于执行该方法的计量装置。

    Article comprising a multi-channel dispensing head
    119.
    发明授权
    Article comprising a multi-channel dispensing head 失效

    公开(公告)号：US06786253B2

    公开(公告)日：2004-09-07

    申请号：US10660251

    申请日：2003-09-11

    申请人： Ilya Feygin

    发明人： Ilya Feygin

    IPC分类号： B65B104

    CPC分类号： B01L3/0265 ,  B01J3/002 ,  B01J3/03 ,  B01J4/02 ,  B01J2219/00274 ,  B01J2219/00315 ,  B01J2219/00317 ,  B01J2219/0036 ,  B01J2219/00369 ,  B01J2219/00585 ,  B01L2200/025 ,  B01L2200/146 ,  B01L2400/0633 ,  B01L2400/082 ,  C40B60/14 ,  G01N35/1065 ,  G01N2035/1041 ,  G01N2035/1044

    摘要： A multi-channel fluid dispenser includes a reservoir with multiple internal chambers, a multi-channel liquid dispensing head, a plurality of fluid-delivery conduits, and support and positioning elements. The fluid-delivery conduits receive liquid from the chambers in the reservoir and deliver it to the dispensing head. The support and positioning elements are operable to support and position the dispensing head so that it can deliver the liquid from the reservoir to an underlying receiver. The fluid-delivery conduits include one or more optional flow control features that improve the accuracy of the dispensing operation. The multi-channel liquid dispensing head, which includes a valve-support member, a plurality of valves and a plurality of nozzles, is advantageously movable in three directions to facilitate alignment with an underlying receiver. Movement of the dispensing head along two axes is provided by the simple expedient of elongate holes having their long axes aligned in mutually orthogonal directions. In some embodiments, the valves are tiltable away from the vertical so that liquid dispensed from such tilted valves is directed at a non-normal angle into a receiver.

    Method and apparatus for non-contact electrostatic actuation of droplets
    120.
    发明申请
    Method and apparatus for non-contact electrostatic actuation of droplets 失效
    液滴非接触静电驱动的方法和装置

    公开(公告)号：US20040055536A1

    公开(公告)日：2004-03-25

    申请号：US10253372

    申请日：2002-09-24

    发明人： Pramod Kolar ,  Richard B. Fair

    IPC分类号： C12Q001/68 ,  B05C005/02 ,  B05B005/025

    CPC分类号： B01L3/0241 ,  B01J2219/0036 ,  B01J2219/0065 ,  B01J2219/00653 ,  B01L2200/0626 ,  B01L2300/089 ,  B01L2400/027 ,  B01L2400/0415 ,  B01L2400/0427 ,  B05B5/0255 ,  B41J2002/14395 ,  C40B60/14

    摘要： An apparatus for actuating a droplet comprises a first conductive layer, a second conductive layer, a conductive elongate element, and a voltage source. The first conductive layer comprises a first hydrophobic surface. The second conductive layer comprises a hydrophilic surface facing the first hydrophobic surface. The second conductive layer is axially spaced from the first conductive layer to define a gap therebetween. The conductive medial element is disposed in the gap between the first and second conductive layers, and comprises a second hydrophobic surface. The voltage source communicates with the second conductive layer and the elongate element. By applying a voltage potential between the elongate element and the second conductive layer, droplets can be electrostatically actuated so as to move from the first conductive layer into contact with the second conductive layer. The apparatus is particularly useful in the synthesis of microarrays of biological, chemical, or biochemical samples.

    摘要翻译： 用于致动液滴的装置包括第一导电层，第二导电层，导电细长元件和电压源。 第一导电层包括第一疏水表面。 第二导电层包括面向第一疏水表面的亲水表面。 第二导电层与第一导电层轴向间隔开以限定它们之间的间隙。 导电内侧元件设置在第一和第二导电层之间的间隙中，并且包括第二疏水表面。 电压源与第二导电层和细长元件连通。 通过在细长元件和第二导电层之间施加电压电位，可以静电致动液滴，以便从第一导电层移动到与第二导电层接触。 该装置特别可用于合成生物，化学或生化样品的微阵列。