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公开(公告)号：US10608284B2
公开(公告)日：2020-03-31
申请号：US15036763
申请日：2014-11-17
Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventor： Cyrus Rustomji , Sungho Jin , Taekyoung Kim , Jungmin You , Joseph Wang , Duyoung Choi
IPC: H01M10/0569 , H01G11/60 , C25D5/00 , C25D3/54 , C25D3/44 , H01M10/0564 , C25D3/50 , H01M10/052 , C25D9/08 , C25D17/02 , C25D3/42 , H01M10/0525 , H01G11/22 , H01G11/46 , H01G11/78 , H01G11/86 , H01G11/62 , C25D21/00 , H01M4/38
Abstract: Disclosed are novel electrolytes, and techniques for making and devices using such electrolytes, which are based on compressed gas solvents. Unlike conventional electrolytes, disclosed electrolytes are based on “compressed gas solvents” mixed with various salts, referred to as “compressed gas electrolytes.” Various embodiments of a compressed gas solvent includes a material that is in a gas phase and has a vapor pressure above an atmospheric pressure at a room temperature. The disclosed compressed gas electrolytes can have wide electrochemical potential windows, high conductivity, low temperature capability and/or high pressure solvent properties.
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22.发明授权公开(公告)号：US10520459B2
公开(公告)日：2019-12-31
申请号：US15616660
申请日：2017-06-07
Inventor： Joseph Wang , Joshua Ray Windmiller , Aoife O'Mahony , Xavier Cetó , Manel Del Valle
Abstract: Methods, systems, and devices are disclosed for the identification of chemical agents and determination of their level of exposure using electrochemical detection and advanced signal processing. In one aspect, a method includes collecting a sample from a surface containing a chemical agent to an electrode on a sensor such that the chemical agent transfers on the electrode, detecting an electrochemical signal of the chemical agent on the electrode to transduce chemical information associated with the chemical agent to an electrical signal, processing the electrical signal to obtain electrochemical spectral signature data to identify the chemical agent and generating a series of coefficients of the electrochemical spectral signature data to reduce the data, and classifying the chemical information based on the series of coefficients among preselected data sets to determine a level of exposure to the chemical agent.
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公开(公告)号：US10364452B2
公开(公告)日：2019-07-30
申请号：US15312733
申请日：2015-06-01
Inventor： Joseph Wang , Irene Litvan , Joshua Ray Windmiller
IPC: G01N27/327 , C12Q1/00 , C12Q1/26 , G01N33/543
Abstract: Methods, systems, and devices are disclosed for providing test strip electrochemical sensors for rapid quantitative analysis of analytes in physiological fluids. In one aspect, an electrochemical sensor includes a substrate; an electrode contingent including a first electrode having a coating of carbon nanotubes (CNTs) and a second electrode on the substrate; and an entrapment layer formed on the first electrode to attach an enzymatic substance capable of causing a redox reaction in the presence of a target analyte of a fluid sample which produces a redox-active product, in which the entrapment layer is structured to include a conductive polymer film that is reversibly dopable to conduct charge carriers across the entrapment layer and at the first electrode. For example, the electrochemical sensor can be provided on a disposable test strip to quantify L-DOPA levels in whole blood, plasma, or serum samples.
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公开(公告)号：US20190159337A1
公开(公告)日：2019-05-23
申请号：US16189701
申请日：2018-11-13
Applicant: The Regents of the University of California
Inventor： Joseph Wang , Rajan Kumar , Ying Shirley Meng , Jae Wook Shin , Lu Yin
IPC: H05K1/02 , H01M4/66 , A61B5/1477 , H01M4/38 , H01M4/48 , H01M4/62 , C08L53/02 , H05K1/03 , H05K1/11 , H05K1/16 , H05K3/32 , H01M10/24 , C08F297/04
Abstract: Disclosed are compositions, devices, systems and fabrication methods for stretchable composite materials and stretchable electronics devices. In some aspects, an elastic composite material for a stretchable electronics device includes a first material having a particular electrical, mechanical or optical property; and a multi-block copolymer configured to form a hyperelastic binder that creates contact between the first material and the multi-block copolymer, in which the elastic composite material is structured to stretch at least 500% in at least one direction of the material and to exhibit the particular electrical, mechanical or optical property imparted from the first material. In some aspects, the stretchable electronics device includes a stretchable battery, biofuel cell, sensor, supercapacitor or other device able to be mounted to skin, clothing or other surface of a user or object.
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公开(公告)号：US20180220967A1
公开(公告)日：2018-08-09
申请号：US15806216
申请日：2017-11-07
Applicant: The Regents of the University of California
Inventor： Joseph Wang , Joshua Ray Windmiller , Amay Jairaj Bandodkar
IPC: A61B5/00 , A61B5/145 , A61B5/1477 , A61B5/1486 , B32B37/12 , B32B38/10 , B32B38/00
CPC classification number: A61B5/6833 , A61B5/14517 , A61B5/14539 , A61B5/1477 , A61B5/1486 , B32B37/1284 , B32B38/10 , B32B38/145 , B32B2255/12 , B32B2307/202 , B32B2307/206 , B32B2311/02 , B32B2323/04 , B32B2367/00 , B32B2383/00 , B32B2405/00 , B32B2556/00 , Y10T156/10
Abstract: Methods, structures, devices and systems are disclosed for fabricating and implementing electrochemical biosensors and chemical sensors. In one aspect, a method of producing an epidermal biosensor includes forming an electrode pattern onto a coated surface of a paper-based substrate to form an electrochemical sensor, the electrode pattern including an electrically conductive material and an electrically insulative material configured in a particular design layout, and attaching an adhesive sheet on a surface of the electrochemical sensor having the electrode pattern, the adhesive sheet capable of adhering to skin or a wearable item, in which the electrochemical sensor, when attached to the skin or the wearable item, is operable to detect chemical analytes within an external environment.
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Patent Agency Ranking
公开(公告)号：US09982356B2
公开(公告)日：2018-05-29
申请号：US15161615
申请日：2016-05-23
Applicant: The Regents of the University of California
Inventor： Joseph Wang , Wei Gao , Sirilak Sattayasamitsathit
IPC: B01J23/42 , C25D1/02 , B82Y30/00 , G01N33/487 , A61K9/70 , A61K47/02 , A61K47/34 , B01J20/22 , B01J23/89 , B01J31/06 , B01J35/00 , B01J35/02 , B01J37/02 , C25D1/00 , C25D1/20 , C25D3/12 , B01J23/40 , B01J21/00 , B01J23/00 , B01J25/00 , B01J29/00 , F03H99/00 , B82Y15/00
CPC classification number: C25D1/02 , A61K9/70 , A61K47/02 , A61K47/34 , B01J20/22 , B01J23/42 , B01J23/8906 , B01J23/8913 , B01J23/892 , B01J31/06 , B01J35/0006 , B01J35/0033 , B01J35/02 , B01J37/0215 , B01J37/0244 , B01J2231/005 , B01J2531/005 , B82Y15/00 , B82Y30/00 , C25D1/006 , C25D1/20 , C25D3/12 , F03H99/00 , G01N33/48707
Abstract: Methods, structures, devices and systems are disclosed for fabrication of microtube engines using membrane template electrodeposition. Such nanomotors operate based on bubble-induced propulsion in biological fluids and salt-rich environments. In one aspect, fabricating microengines includes depositing a polymer layer on a membrane template, depositing a conductive metal layer on the polymer layer, and dissolving the membrane template to release the multilayer microtubes.
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27.发明申请公开(公告)号：US20180030497A1
公开(公告)日：2018-02-01
申请号：US15548735
申请日：2016-02-05
Applicant: The Regents of the University of California
Inventor： Joseph Wang , Amay Jairaj Bandodkar
IPC: C12Q1/00 , G01N27/327 , A61B5/00 , A61B5/145 , A61B5/1486
CPC classification number: C12Q1/006 , A61B5/02 , A61B5/14532 , A61B5/1486 , A61B5/6898 , C12Q1/001 , G01N27/3271 , G01N27/3272
Abstract: Methods, systems, and devices are disclosed for providing a portable enzymatic-ink dispensing system. The system includes an enzymatic-ink including one or more biocompatible binders, one or more biocompatible mediators, an enzyme, an enzyme stabilizer, and a conductive material. The system includes a dispenser including a chamber to hold the enzymatic-ink and an applicator to apply the enzymatic ink dispensed from the chamber onto a target substrate.
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公开(公告)号：US09844339B2
公开(公告)日：2017-12-19
申请号：US14846412
申请日：2015-09-04
Applicant: The Regents of the University of California
Inventor： Joseph Wang , Joshua Ray Windmiller
IPC: A61B5/145 , A61B5/00 , A61B5/1477 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/0245 , C12Q1/00 , G01N27/30 , G01N33/22 , A61B5/1486 , A41D1/00 , G01N27/327 , G01N33/00 , H05K1/03 , H05K3/12
CPC classification number: A61B5/6804 , A41D1/002 , A61B5/0002 , A61B5/0205 , A61B5/021 , A61B5/02444 , A61B5/0245 , A61B5/14517 , A61B5/14532 , A61B5/14546 , A61B5/1477 , A61B5/1486 , A61B5/4266 , A61B5/4845 , A61B5/4884 , A61B5/6802 , A61B5/6807 , A61B5/6808 , A61B5/6831 , A61B5/742 , A61B2560/0214 , C12Q1/001 , G01N27/308 , G01N27/3271 , G01N33/0057 , G01N33/22 , H05K1/038 , H05K3/1216
Abstract: Techniques and systems are disclosed for implementing textile-based screen-printed amperometric or potentiometric sensors. The chemical sensor can include carbon based electrodes to detect at least one of NADH, hydrogen peroxide, potassium ferrocyanide, TNT or DNT, in liquid or vapor phase. In one application, underwater presence of chemicals such as heavy metals and explosives is detected using the textile-based sensors.
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公开(公告)号：US20170226557A1
公开(公告)日：2017-08-10
申请号：US15312733
申请日：2015-06-01
Inventor： Joseph Wang , Irene Litvan , Joshua Ray Windmiller
IPC: C12Q1/00 , G01N33/543 , G01N27/327 , C12Q1/26
CPC classification number: C12Q1/005 , C12Q1/26 , G01N27/3272 , G01N27/3273 , G01N27/3278 , G01N33/5438
Abstract: Methods, systems, and devices are disclosed for providing test strip electrochemical sensors for rapid quantitative analysis of analytes in physiological fluids. In one aspect, an electrochemical sensor includes a substrate; an electrode contingent including a first electrode having a coating of carbon nanotubes (CNTs) and a second electrode on the substrate; and an entrapment layer formed on the first electrode to attach an enzymatic substance capable of causing a redox reaction in the presence of a target analyte of a fluid sample which produces a redox-active product, in which the entrapment layer is structured to include a conductive polymer film that is reversibly dopable to conduct charge carriers across the entrapment layer and at the first electrode. For example, the electrochemical sensor can be provided on a disposable test strip to quantify L-DOPA levels in whole blood, plasma, or serum samples.
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公开(公告)号：US20170143830A1
公开(公告)日：2017-05-25
申请号：US15356977
申请日：2016-11-21
Applicant: The Regents of the University of California
Inventor： Joseph Wang , Liangfang Zhang
CPC classification number: A61K49/0097 , A61K9/0009 , A61K9/5094 , A61K9/5115 , A61K35/18 , A61K41/00 , A61K47/6901 , A61K49/0067 , A61K2035/124
Abstract: Living cells, such as red blood cells (RBCs) modified with functional micromotors with the aid of ultrasound propulsion and magnetic guidance. Iron oxide nanoparticles are loaded into the RBCs, where their asymmetric distribution within the cells results in a net magnetization, thus enabling magnetic alignment and guidance under acoustic propulsion. The RBC motors display efficient guided and prolonged propulsion in various biological fluids, including undiluted whole blood.
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