High-potency sweetener for weight management and compositions sweetened therewith
    24.
    发明授权
    High-potency sweetener for weight management and compositions sweetened therewith 有权
    用于体重管理的高效甜味剂和具有甜味剂的组合物

    公开(公告)号:US08945652B2

    公开(公告)日:2015-02-03

    申请号:US11556140

    申请日:2006-11-02

    IPC分类号: A23L1/236 A23L2/60 A23L2/68

    摘要: The present invention relates generally to functional sweetener compositions comprising non-caloric or low-caloric natural and/or synthetic high-potency sweeteners and methods for making and using them. In particular, the present invention relates to different functional sweetener compositions comprising at least one non-caloric or low-caloric natural and/or synthetic high potency sweetener, at least one sweet taste improving composition, and at least one functional ingredient, such as a weight management agent. The present invention also relates to functional sweetener compositions and methods that can improve the tastes of non-caloric or low-caloric high-potency sweeteners by imparting a more sugar-like taste or characteristic. In particular, the functional sweetener compositions and methods provide a more sugar-like temporal profile, including sweetness onset and sweetness linger, and/or a more sugar-like flavor profile.

    摘要翻译: 本发明一般涉及包含非热量或低热量天然和/或合成高效甜味剂的功能甜味剂组合物及其制备和使用方法。 特别地,本发明涉及包含至少一种非热量或低热量天然和/或合成高效甜味剂,至少一种甜味改善组合物和至少一种功能成分的不同功能甜味剂组合物,例如 体重管理代理。 本发明还涉及功能性甜味剂组合物和方法,其可以通过赋予更多的糖样味道或特征来改善非热量或低热量的高效甜味剂的口味。 特别地,功能性甜味剂组合物和方法提供了更多的糖样时间分布,包括甜度起始和甜度徘徊,和/或更多的糖样香味。

    Targeted Buccal Delivery of Agents
    25.
    发明申请
    Targeted Buccal Delivery of Agents 审中-公开
    有针对性的交货代理

    公开(公告)号:US20140234212A1

    公开(公告)日:2014-08-21

    申请号:US14186977

    申请日:2014-02-21

    IPC分类号: A61K9/00 A61K47/36 A61K33/24

    摘要: A delivery device for topical and systemic delivery of agents to targeted oral locations, such as mouth cancer cells, has been developed. The formulation includes a mucoadhesive polymeric matrix such as chitosan, which contains one or more therapeutic and/or diagnostic agents, taste masking agents, permeation enhancers, the therapeutic or diagnostic agent to be delivered, and a hydrophilic polymeric coating such as polyethyleneglycol (“PEG”). In the preferred embodiment, the matrix is formulated with one side having the PEG-mucoadhesive polymer exposed for topical placement onto epithelial or cancer cells in the mouth or other mucosal area and the side(s) facing the inside of the oral cavity being covered with a biocompatible, inert membrane that is impermeable to the therapeutic and/or diagnostic agent(s) to be delivered.

    摘要翻译: 已经开发了用于局部和全身递送药物到靶向口腔位置(例如口腔癌细胞)的递送装置。 制剂包括粘膜粘附聚合物基质如壳聚糖,其含有一种或多种治疗和/或诊断剂,掩味剂,渗透促进剂,待递送的治疗剂或诊断剂,以及亲水性聚合物涂层如聚乙二醇(“PEG “)。 在优选的实施方案中,基质被配制成具有暴露于口腔或其它粘膜区域中的上皮细胞或癌细胞上的PEG-粘膜粘附聚合物的一侧,并且面向口腔内侧的一侧被覆盖 生物相容的惰性膜,其不可渗透到待递送的治疗和/或诊断剂。