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51.
公开(公告)号:US09931627B2
公开(公告)日:2018-04-03
申请号:US15021493
申请日:2014-09-09
Applicant: GILSON SAS
Inventor: Marc Sanchez
IPC: B01L3/02
CPC classification number: B01L3/0224 , B01L2200/08 , B01L2200/148 , B01L2300/026 , B01L2300/028 , B01L2400/0478
Abstract: A top part for a sampling pipette including a hollow outer body forming a handle, a pipetting control stem, a device for adjusting and displaying a volume to be sampled, including a first threaded member for adjusting the volume to be sampled crossed by the control stem, the device also comprising a set of first volume graduations angularly spaced from one another around the longitudinal axis and cooperating with a first mark so as to inform about the volume to be sampled. The first threaded member is rotatably integral with one of both elements formed by the set of first volume graduations and the first mark, the mark being axially arranged between the hollow outer body forming a handle and the control knob.
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公开(公告)号:US09931625B2
公开(公告)日:2018-04-03
申请号:US14779518
申请日:2014-03-21
Applicant: GILSON SAS
Inventor: Claude Voyeux , Stephane Guichardon
IPC: B01L3/02
CPC classification number: B01L3/022 , B01L3/0279 , B01L2200/04 , B01L2300/0609 , B01L2300/0838 , B01L2400/0478
Abstract: A bottom part of a positive-displacement pipetting system), including a body slideably housing a device for gripping a piston belonging to a capillary-piston assembly the capillary of which is adapted to be fitted onto an end-fitting of the body. The system also comprises means for ejecting the capillary-piston assembly arranged externally with respect to the body. The system is constructed so that a relative rotation between the ejection means and the gripping device causes it to pass from an open configuration enabling the piston to be released to a closed configuration enabling said piston to be retained, and/or the reverse.
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公开(公告)号:US20180071733A1
公开(公告)日:2018-03-15
申请号:US15812104
申请日:2017-11-14
Applicant: DxNA LLC
Inventor: Ray Cracauer , Clark Braten , William D. Bickmore , Doyle Hansen , Ernie Sumsion , Frank Spangler , Brent L. Weight , Darryl K. Zitting
CPC classification number: B01L3/502715 , B01F11/0082 , B01F13/0818 , B01L3/502723 , B01L3/5029 , B01L7/52 , B01L2200/0684 , B01L2200/146 , B01L2300/022 , B01L2300/0654 , B01L2300/0681 , B01L2300/123 , B01L2300/14 , B01L2400/0478 , C12Q1/686
Abstract: A sample processing module includes a PCR assembly including at least one PCR reaction vial. A sample assembly is configured to hold a fluid sample therein, said sample assembly being attachable to said PCR assembly so as to form a closed system. A delivery channel is formed in said PCR assembly, said delivery channel being in fluidic communication with said PCR reaction vial and with said sample assembly. A pressurization device, said pressurization device being configured to increase a pressure of said fluid sample in said sample assembly and direct at least a portion said fluid sample through said delivery channel to said PCR reaction vial. A chemically inert magnetically responsive bead is disposed within the PCR reaction vial. A system is provided for oscillating for altering a position of the magnetically responsive bead within the PCR reaction vial.
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54.
公开(公告)号:US20180066300A1
公开(公告)日:2018-03-08
申请号:US15790499
申请日:2017-10-23
Applicant: FUNDAMENTAL SOLUTIONS CORPORATION
Inventor: Marvin R. WILLIAMS , Charles MCBRAIRTY , Andrew WEIMAN , Daniel W. PFAUTZ , Thomas J. ZUPANCIC
CPC classification number: C12Q1/04 , B01L3/50 , B01L3/502 , B01L3/527 , B01L2200/026 , B01L2200/16 , B01L2300/022 , B01L2300/044 , B01L2300/047 , B01L2300/0816 , B01L2300/0883 , B01L2300/168 , B01L2400/0478 , G01N17/002 , G01N21/63 , G01N21/763 , G01N33/02 , G01N33/025 , G01N33/12 , G01N33/56916 , G01N2021/0325 , G01N2201/0221 , G01N2333/245
Abstract: A method for enhancing the performance of a reaction chamber for use in a sample analysis system that includes providing a reaction chamber, wherein the reaction chamber has a predetermined geometry, wherein the reaction chamber has light collecting properties, and wherein the reaction chamber has an inner surface; and modifying the inner surface of the reaction chamber to include a predetermined degree of reflectivity, wherein the predetermined degree of reflectivity enhances the light collecting properties of the reaction chamber.
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公开(公告)号:US20180066248A1
公开(公告)日:2018-03-08
申请号:US15808183
申请日:2017-11-09
Applicant: NeuMoDx Molecular, Inc.
Inventor: Michael T. Kusner , Sundaresh Brahmasandra , Jeffrey Williams , Robert Jaekel
IPC: C12N15/10 , C12Q1/68 , C12M3/00 , B01L9/00 , B01L7/00 , B01L3/00 , C12N13/00 , B29K21/00 , B29C65/00 , B29C65/60 , B29C65/48 , B29C65/08 , B29L31/00
CPC classification number: C12N15/1013 , B01L3/502 , B01L3/5025 , B01L3/5027 , B01L3/502707 , B01L3/502715 , B01L3/502723 , B01L3/50273 , B01L3/502738 , B01L3/502746 , B01L3/502761 , B01L3/508 , B01L3/523 , B01L3/527 , B01L3/567 , B01L7/52 , B01L7/525 , B01L9/00 , B01L2200/025 , B01L2200/0605 , B01L2200/0615 , B01L2200/0668 , B01L2200/0684 , B01L2200/0689 , B01L2200/10 , B01L2200/12 , B01L2200/142 , B01L2300/021 , B01L2300/022 , B01L2300/044 , B01L2300/06 , B01L2300/0609 , B01L2300/0627 , B01L2300/0636 , B01L2300/0672 , B01L2300/0681 , B01L2300/0809 , B01L2300/0816 , B01L2300/0861 , B01L2300/0864 , B01L2300/0867 , B01L2300/087 , B01L2300/0883 , B01L2300/0887 , B01L2300/0893 , B01L2300/123 , B01L2300/14 , B01L2300/16 , B01L2300/1822 , B01L2300/1827 , B01L2400/0406 , B01L2400/043 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0622 , B01L2400/065 , B01L2400/0655 , B01L2400/0694 , B01L2400/086 , B29C65/08 , B29C65/484 , B29C65/606 , B29C66/1122 , B29C66/21 , B29C66/3022 , B29C66/542 , B29C66/71 , B29C66/81423 , B29C66/8322 , B29K2021/00 , B29L2031/756 , B81B2201/054 , B81C1/00119 , B81C3/001 , B81C2203/032 , C12M23/16 , C12M23/42 , C12M25/02 , C12N13/00 , C12Q1/68 , C12Q1/6806 , C12Q1/6813 , C12Q1/686 , C12Q2565/629
Abstract: A system, configured to facilitate processing and detection of nucleic acids, the system comprising a process fluid container and a cartridge comprising: a top layer, a set of sample port-reagent port pairs, a shared fluid port, a vent region, a heating region, and a set of detection chambers; an intermediate substrate, coupled to the top layer comprising a waste chamber; an elastomeric layer, partially situated on the intermediate substrate; and a set of fluidic pathways, each formed by at least a portion of the top layer and a portion of the elastomeric layer, wherein each fluidic pathway is fluidically coupled to a sample port-reagent port pair, the shared fluid port, and a detection chamber, comprises a portion passing through the heating region, and is configured to be occluded upon deformation of the elastomeric layer, to transfer a waste fluid to the waste chamber, and to pass through the vent region.
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公开(公告)号:US20180064383A1
公开(公告)日:2018-03-08
申请号:US15687223
申请日:2017-08-25
Applicant: Shih-Hua HUANG , Fang-Tsern LIU , Tzu-Chun LIU
Inventor: Shih-Hua HUANG , Fang-Tsern LIU , Tzu-Chun LIU
CPC classification number: A61B5/153 , A61B5/15003 , A61B5/150236 , A61B5/150244 , A61B5/150351 , A61B5/150389 , A61B5/150503 , A61B5/150824 , A61M5/178 , B01L3/5021 , B01L2200/026 , B01L2200/028 , B01L2200/0689 , B01L2300/028 , B01L2400/0409 , B01L2400/0478
Abstract: The present invention relates to a multi-functional specimen collector, comprising: a barrel on a surface thereof are marked a first graduated section and a second graduated section; a shaft body disposed in the barrel; a piston disposed in the barrel and connected to the shaft body; a first seal cap connected to an end of the barrel; and a second seal cap for connecting to the piston after the shaft body is removed. When a needle is fitted to the barrel, a specimen is extracted into the barrel with the coordination of the needle, the shaft body and the piston; after extraction the needle and the shaft body are removed, and the barrel is sealed up with a first seal cap and a second seal cap respectively for subsequent centrifugal treatment of the specimen; and then the first and second seal caps are removed for expelling any wanted or unwanted specimen materials from the barrel at the push of the shaft body; wherein the double effect of specimen extraction and expulsion is achieved, and wherein an accurate volume of specimen may be extracted or expelled with the help of the first and second graduated sections marked on the barrel.
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公开(公告)号:US20180021783A1
公开(公告)日:2018-01-25
申请号:US15547788
申请日:2016-02-02
Applicant: Atlas Genetics Limited
Inventor: Ben Arlett , Tom Edwards
CPC classification number: B01L3/527 , B01L3/502738 , B01L7/52 , B01L7/525 , B01L2200/025 , B01L2200/028 , B01L2200/04 , B01L2200/14 , B01L2200/146 , B01L2300/021 , B01L2300/0809 , B01L2300/0816 , B01L2300/0874 , B01L2300/0887 , B01L2300/123 , B01L2300/1822 , B01L2400/0478 , B01L2400/0481 , B01L2400/0487 , B01L2400/0666 , B01L2400/0683 , G01N35/00029 , G01N35/1002 , G01N2035/1044
Abstract: Instrument for performing a diagnostic test on a fluidic cartridge A cartridge reader is for carrying out a diagnostic test on a sample contained in a fluidic cartridge inserted into the reader. The fluidic cartridge comprises a fluidic layer comprising at least one sample processing region, at least one collapsible blister containing a liquid reagent, a pneumatic interface, an electrical interface and at least one mechanical valve. The reader comprises a housing; an upper clamp occupying a fixed position relative to the reader, and a lower clamp, movable relative to the first clamp, wherein the upper clamp and the lower clamp define a cartridge receiving region therebetween. The reader comprises a thermal module comprised in the lower clamp, wherein the thermal module comprises at least one thermal stack for heating the at least one sample processing region of the cartridge inserted into the reader. The reader comprises at least one mechanical actuator for actuating the mechanical valve comprised in the cartridge inserted into the reader.
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公开(公告)号:US09857332B2
公开(公告)日:2018-01-02
申请号:US13737360
申请日:2013-01-09
Applicant: Tecan Trading AG
Inventor: Travis Lee , Michael Benjamin Franklin , Kailiang Wang , Anne R. Kopf-Sill
IPC: G01N27/447 , B01L3/00 , B01L7/00
CPC classification number: G01N27/44791 , B01L3/502715 , B01L3/502738 , B01L3/502792 , B01L3/5029 , B01L3/523 , B01L3/527 , B01L7/52 , B01L2200/025 , B01L2200/027 , B01L2200/04 , B01L2200/0647 , B01L2200/141 , B01L2300/044 , B01L2300/0672 , B01L2300/0681 , B01L2300/0829 , B01L2300/0864 , B01L2300/0867 , B01L2300/0887 , B01L2300/089 , B01L2300/161 , B01L2400/0427 , B01L2400/043 , B01L2400/0478 , B01L2400/0683
Abstract: A liquid droplet manipulation system has a substrate with at least one electrode array and a central control unit for controlling selection of individual electrodes of the electrode array and for providing the electrodes with individual voltage pulses for manipulating liquid droplets by electrowetting. A working film is placed on top of the electrodes for manipulating samples in liquid droplets with the electrode array. At least one selected individual electrode of the electrode array is configured to be penetrated by light of an optical detection system for the optical inspection or analysis of samples in liquid droplets that are located on the working film. Also disclosed is working film that is to be placed on the electrode array and a cartridge that includes such a working film for manipulating samples in liquid droplets.
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59.
公开(公告)号:US20170348476A1
公开(公告)日:2017-12-07
申请号:US15541182
申请日:2015-01-09
Applicant: West Pharmaceutical Services, Inc. , Daikyo Seiko, Ltd.
Inventor: James THOMPSON , Timothy BROMMER , Hideaki KAWAMURA
CPC classification number: A61M5/001 , A61M5/008 , A61M2207/00 , B01L3/5085 , B01L3/50853 , B01L2200/025 , B01L2200/141 , B01L2300/047 , B01L2300/048 , B01L2300/069 , B01L2300/0809 , B01L2300/089 , B01L2300/123 , B01L2400/0478 , B65D25/108 , B65D71/70
Abstract: A cover for a drug container piston array includes a plurality of cover sections configured for positioning over the drug container piston array. Each cover section includes an elongated cover section body having an open base end and a closed capped end, and a plurality of base sections or a web positioned between the plurality of cover sections and coupled to each base end. Packaging assemblies including a cover and a piston nest are also disclosed.
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公开(公告)号:US20170343523A1
公开(公告)日:2017-11-30
申请号:US15534275
申请日:2015-12-08
Applicant: LAR PROCESS ANALYSERS AG
Inventor: Werner Arts , Wolfgang Genthe
CPC classification number: G01N33/1806 , B01L3/50 , B01L2200/025 , B01L2200/0642 , B01L2200/16 , B01L2300/0672 , B01L2300/0832 , B01L2300/14 , B01L2400/0478 , G01N1/14 , G01N31/12 , G01N33/1846
Abstract: Disclosed is an analysis system for analyzing water and wastewater, comprising an analysis device that includes a device housing which accommodates device components and which has an inlet on a housing surface, said inlet being designed as an injection port through which a substance to be analyzed can be introduced into a device component when the device housing is closed, and comprising a syringe that includes an injection needle outlet, the surface normal of which is congruent with the longitudinal axis; and/or the syringe includes an automatic ejection element for ejecting a predetermined amount of substance within a predetermined injection period.
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