公开(公告)号：US20170135641A1

公开(公告)日：2017-05-18

申请号：US15336820

申请日：2016-10-28

Applicant: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY

Inventor： Jong-Hyun LEE ,  Joho YUN ,  Hyeon Woo KIM ,  Yangkyu PARK

IPC: A61B5/00 ,  A61N1/05 ,  A61B5/04

CPC classification number: A61B5/6848 ,  A61B5/04 ,  A61B2562/028 ,  A61B2562/04 ,  A61B2562/125 ,  A61N1/0502

Abstract: Disclosed herein are a method of manufacturing multiple microelectrodes on a syringe needle and a syringe needle manufactured by the same. The syringe needle includes multiple interdigitated electrodes (IDEs) placed on a surface of a portion of the syringe needle spaced apart from a tip of the syringe needle, a pair of interconnection lines for electrical connection of the multiple IDEs, the interconnection lines electrically connecting a first group of the IDEs on the left and a second group of the IDEs on the right through one end of each of the interconnection lines, and a conductor for electrical connection to a PCB provided to a main body of a syringe at the other end of each of the interconnection lines, wherein the multiple IDEs are basically formed of a material for a dielectric layer and are alternately arranged at a first distance from one another.

公开(公告)号：US20170128015A1

公开(公告)日：2017-05-11

申请号：US15349525

申请日：2016-11-11

Applicant: The Board of Trustees of the University of Illinois

Inventor： John A. ROGERS ,  Ki Jun YU

IPC: A61B5/00 ,  A61L31/02 ,  A61N1/05 ,  A61L31/14 ,  A61B5/0478 ,  A61B5/04

CPC classification number: A61B5/6868 ,  A61B5/04001 ,  A61B5/04284 ,  A61B5/0478 ,  A61B2562/0209 ,  A61B2562/046 ,  A61B2562/125 ,  A61L31/022 ,  A61L31/028 ,  A61L31/06 ,  A61L31/14 ,  A61L31/148 ,  A61N1/0529 ,  C08L83/04

Abstract: Provided are implantable and bioresorbable medical devices comprising a bioresorbable substrate and an electronic circuit supported by the bioresorbable substrate. The electronic circuit comprises a membrane of silicon having a thickness less than or equal to 5 μm and an array of dissolvable electrodes, wherein the dissolvable electrodes are formed from the membrane of silicon. The electronic circuit is configured to conformally contact a biological tissue and electrically interface with biological tissue during use. The silicon may be highly doped to provide the requisite characteristics for electrically interfacing with biological tissue, and may be further used to form other components of the electronic circuit, including back-plane transistors electrically connected to the electrode array.

公开(公告)号：US20170106461A1

公开(公告)日：2017-04-20

申请号：US14886761

申请日：2015-10-19

Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.

Inventor： Assaf Govari ,  Christopher Thomas Beeckler ,  Joseph Thomas Keyes

IPC: B23H1/04 ,  A61B5/0478 ,  A61B5/042

CPC classification number: B23H1/04 ,  A61B5/0408 ,  A61B5/042 ,  A61B5/0478 ,  A61B18/1492 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/1417 ,  A61B2562/0209 ,  A61B2562/125 ,  A61N1/0529 ,  A61N1/0565 ,  Y10T29/49174

Abstract: A method, consisting of providing a metal wire having a wire diameter and an end, and positioning a conductor at a distance from the end of the wire. The method further includes creating an electrical discharge between the conductor and the end, while setting the distance and an electrical potential of the discharge, so as to create a bead of a predefined size on the end. The method also includes assembling the wire with the created bead into an invasive probe, so that the bead is positioned at an outer surface of the probe.

公开(公告)号：US20170087353A1

公开(公告)日：2017-03-30

申请号：US15202551

申请日：2016-07-05

Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES

Inventor： Anil K. Thota ,  Ranu Jung ,  Sathyakumar S. Kuntaegowdanahalli

IPC: A61N1/05 ,  A61B5/00 ,  A61B5/0488 ,  A61B5/04

CPC classification number: A61N1/0558 ,  A61B5/04001 ,  A61B5/0488 ,  A61B5/04888 ,  A61B5/4029 ,  A61B5/4076 ,  A61B5/6839 ,  A61B5/6877 ,  A61B2562/125 ,  A61B2562/18 ,  A61B2562/245 ,  A61N1/05 ,  A61N1/0507 ,  Y10T29/49208

Abstract: A multi-lead multi-electrode system and method of manufacturing the multi-lead multi-electrode system includes a multi-electrode lead that may be used to deploy multiple separable electrodes to different spaced apart contact sites, such as nerve or muscle tissues, for example, that are spatially distributed over a large area.

公开(公告)号：US20170086724A1

公开(公告)日：2017-03-30

申请号：US15377407

申请日：2016-12-13

Applicant: Sano Intelligence, Inc.

Inventor： Ashwin Pushpala ,  Alan Szmodis ,  Matthew Chapman ,  Weldon Hall ,  Scott Miller ,  Hooman Hafezi

IPC: A61B5/1486 ,  C12Q1/00 ,  A61B5/00 ,  G01N27/327 ,  A61B5/145 ,  A61B5/15

CPC classification number: A61M37/0015 ,  A61B5/14503 ,  A61B5/14514 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/14865 ,  A61B5/1495 ,  A61B5/150022 ,  A61B5/150282 ,  A61B5/150427 ,  A61B5/150969 ,  A61B5/150984 ,  A61B5/4839 ,  A61B5/685 ,  A61B2562/028 ,  A61B2562/12 ,  A61B2562/125 ,  A61M25/00 ,  A61M2037/0023 ,  A61M2037/0046 ,  A61M2037/0053 ,  C12Q1/006 ,  G01N27/3271 ,  Y10T29/49117

Abstract: A microsensor and method of manufacture for a microsensor, comprising an array of filaments, wherein each filament of the array of filaments comprises a substrate and a conductive layer coupled to the substrate and configured to facilitate analyte detection. Each filament of the array of filaments can further comprise an insulating layer configured to isolate regions defined by the conductive layer for analyte detection, a sensing layer coupled to the conductive layer, configured to enable transduction of an ionic concentration to an electronic voltage, and a selective coating coupled to the sensing layer, configured to facilitate detection of specific target analytes/ions. The microsensor facilitates detection of at least one analyte present in a body fluid of a user interfacing with the microsensor.

公开(公告)号：US09598799B2

公开(公告)日：2017-03-21

申请号：US15203690

申请日：2016-07-06

Applicant: HEALTHWATCH LTD.

Inventor： Boaz Shoshani ,  Uri Amir

IPC: D04B1/24 ,  A61B5/00 ,  A61B5/0402 ,  A61B5/0408 ,  D04B1/18 ,  B32B27/12

CPC classification number: D04B1/246 ,  A41D2400/32 ,  A61B5/0006 ,  A61B5/0402 ,  A61B5/04085 ,  A61B5/6804 ,  A61B5/6805 ,  A61B2562/125 ,  B32B5/026 ,  B32B27/12 ,  B32B2307/536 ,  B32B2437/00 ,  B32B2535/00 ,  D04B1/18 ,  D04B1/24 ,  D06N7/0094 ,  D06N2209/108 ,  D10B2403/02431 ,  G06F1/16 ,  G06F1/163

Abstract: A method for stabilizing the physical dimensions and positioning of at least one selected textile region of a knitted garment. The method includes producing the garment including a conductive textile electrode, rigidifying the at least one selected textile region and knitting a preconfigured region proximal to the at least one selected textile region with a lower knitting density than the preconfigured density of the tubular form. The invention further provides a garment having a tubular form, knitted by a seamless knitting machine with base-yarns. The garment includes at least one conductive textile electrode. The garment further includes at least one preconfigured region in proximity to the at least one selected textile region, having a lower knitting density than the preconfigured density of the tubular form and the at least one selected textile region.

公开(公告)号：US20170055892A1

公开(公告)日：2017-03-02

申请号：US15272225

申请日：2016-09-21

Applicant: Medtronic MiniMed, Inc.

Inventor： Megan E. Little ,  Katherine T. Wolfe ,  Raghavendhar Gautham ,  Bradley Chi Liang ,  Rajiv Shah

IPC: A61B5/145 ,  G01N27/327 ,  A61B5/1486 ,  C12Q1/00

CPC classification number: A61B5/14532 ,  A61B5/14865 ,  A61B2562/125 ,  A61B2562/166 ,  A61B2562/222 ,  C12Q1/001 ,  C12Q1/006 ,  G01N27/3272 ,  Y10T29/49204

Abstract: The invention disclosed herein includes sensors having three dimensional configurations that allow expansive “360°” sensing (i.e. sensing analyte from multiple directions) in the environments in which such sensors are disposed. Embodiments of the invention provide analyte sensors having foldable substrates adapted to produce optimized configurations of electrode elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes.

Abstract translation: 本文公开的本发明包括具有三维结构的传感器，其在这些传感器被布置的环境中允许宽广的“360°”感测（即感测来自多个方向的分析物）。 本发明的实施例提供了分析物传感器，其具有适于产生电极元件的优化配置的可折叠基底以及用于制造和使用这种传感器的方法。 本发明的典型实施方案包括用于治疗糖尿病的葡萄糖传感器。

公开(公告)号：US20170035958A1

公开(公告)日：2017-02-09

申请号：US15298213

申请日：2016-10-19

Applicant: Abbott Diabetes Care Inc.

Inventor： Christopher Allen Thomas ,  Jasmin Yan Zhao

IPC: A61M5/00 ,  A61L2/20 ,  B65B5/04 ,  B65B7/16 ,  B65B55/10 ,  B65B55/18 ,  B65D65/38 ,  B65D77/26 ,  B65B55/08 ,  B65B55/16 ,  A61B5/145 ,  A61B5/1486 ,  A61B50/39 ,  A61B90/70 ,  A61L2/08

CPC classification number: A61M5/003 ,  A61B5/14532 ,  A61B5/14865 ,  A61B50/39 ,  A61B90/70 ,  A61B2560/0209 ,  A61B2560/0252 ,  A61B2562/12 ,  A61B2562/125 ,  A61L2/08 ,  A61L2/087 ,  A61L2/20 ,  A61L2/206 ,  A61L2202/14 ,  A61L2202/24 ,  B65B5/04 ,  B65B7/16 ,  B65B55/08 ,  B65B55/10 ,  B65B55/16 ,  B65B55/18 ,  B65D65/38 ,  B65D77/26

Abstract: In one aspect, there is provided assembling an analyte sensor with an analyte sensor insertion device, packaging the assembled analyte sensor and sensor insertion device in a substantially airtight seal, and irradiating the packaged assembled analyte sensor and sensor insertion device at a predetermined dose using one or more electron beam accelerators.

Abstract translation: 在一个方面，提供了将分析物传感器与分析物传感器插入装置组装，将组装的分析物传感器和传感器插入装置封装在基本上气密的密封中，并且使用一个以预定的剂量照射封装的组装的分析物传感器和传感器插入装置 或更多的电子束加速器。

公开(公告)号：US20170035502A1

公开(公告)日：2017-02-09

申请号：US15331669

申请日：2016-10-21

Applicant: BIOSENSE WEBSTER (ISRAEL) LTD.

Inventor： Jeffrey L. Clark ,  Maria Duarte ,  Erica Lovejoy

IPC: A61B18/14 ,  A61M25/00 ,  A61M25/01 ,  A61B5/042 ,  A61B5/00

CPC classification number: A61B5/042 ,  A61B5/6852 ,  A61B18/00 ,  A61B18/1492 ,  A61B34/20 ,  A61B2018/00029 ,  A61B2018/00351 ,  A61B2018/00357 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/00839 ,  A61B2218/002 ,  A61B2562/125 ,  A61M25/0009 ,  A61M25/0147 ,  Y10T29/49117 ,  Y10T29/49826

Abstract: A catheter includes a tip electrode with a shell and a support member to provide a plenum chamber. The support member is formed with a U-shaped passage for a safety line to wrap around and secure the support member (with the shell affixed thereto) to the catheter. Additional passages are formed in the support member to accommodate components such as irrigation tubing, lead wires and a thermocouple wire pair. A method of manufacture provides distal installation and/or anchoring of the safety line, lead wire and thermocouple wire pair in the support member prior to sealing the support member and mounting the shell.

Abstract translation: 导管包括具有壳体的尖端电极和用于提供增压室的支撑构件。 支撑构件形成有用于安全线的U形通道，以将支撑构件（其上附着有壳体）固定到导管上并将其固定。 在支撑构件中形成附加通道以容纳诸如冲洗管，引线和热电偶线对的部件。 制造方法在密封支撑构件并安装壳体之前，将安全线，引线和热电偶线对远端安装和/或锚固在支撑构件中。

公开(公告)号：US20170027473A1

公开(公告)日：2017-02-02

申请号：US15096295

申请日：2016-04-12

Applicant: Far Eastern New Century Corporation

Inventor： Hsin-Kai LAI ,  Wei-Che HUNG ,  Yu-June WU ,  Jeffrey-Fu HSU

IPC: A61B5/053 ,  A61B5/00

CPC classification number: A61B5/0531 ,  A61B5/0408 ,  A61B5/0492 ,  A61B5/6804 ,  A61B5/6805 ,  A61B5/7278 ,  A61B2562/0215 ,  A61B2562/125

Abstract: A physiology sensing device and an intelligent textile are provided. The physiology sensing device includes a fabric substrate and a conductive coating layer. The conductive coating layer is embedded from a side of the fabric substrate and leveled with the fabric body, and a thickness of the conductive coating layer is not larger than a thickness of the fabric substrate. The conductive coating layer includes a hydrophobic adhesive and a plurality of conductive particles distributing therein. The physiology sensing device receives variation of a signal of body potential on skin surface. Then a long range signal receiver receives the signal, the signal is shown on a monitory system so as to perform long distance monitoring.

Abstract translation: 提供生理感测装置和智能纺织品。 生理感测装置包括织物基底和导电涂层。 导电涂层从织物基材的一侧嵌入并与织物本体平齐，并且导电涂层的厚度不大于织物基底的厚度。 导电涂层包括疏水性粘合剂和分布在其中的多个导电颗粒。 生理感测装置接收皮肤表面体电位信号的变化。 然后，长距离信号接收器接收信号，信号显示在监控系统上，以进行长距离监视。