公开(公告)号：US20170160132A1

公开(公告)日：2017-06-08

申请号：US15376144

申请日：2016-12-12

Applicant: The General Hospital Corporation

Inventor： Milen Shishkov ,  Guillermo J. Tearney ,  Brett Eugene Bouma ,  Dvir Yelin ,  Nicusor lftimia

IPC: G01J3/18 ,  G02B23/26 ,  B24B9/14 ,  G02B23/24 ,  A61B1/002 ,  G01J3/02

CPC classification number: G02B23/2453 ,  A61B1/00167 ,  A61B1/00188 ,  A61B1/002 ,  A61B5/0062 ,  A61B5/0066 ,  A61B5/0068 ,  A61B5/0084 ,  A61B5/0086 ,  B24B9/14 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/18 ,  G02B5/18 ,  G02B23/2469 ,  G02B23/26

Abstract: Exemplary apparatus for method for forming at least one spectral encoding endoscopy configuration. For example, it is possible to modify a spacer configuration and an lens optics configuration to have respective predetermined lengths, and also to modify a dispersive optics configuration to have a further predetermined length. Further, the modified spacer and modified lens optics configurations can be attached to one another to form a combined spacer-lens optics configuration. The modified dispersive optics configuration can be attached to a substrate to form to form a grating substrate configuration. Additionally, the combined spacer-lens optics configuration can be connected to an optical fiber, and the modified attached dispersed optics configuration can be connected to the modified attached lens optics configuration to form the spectral encoding endoscopy configuration(s) which can extends along a particular axis. The dispersive optics configuration can be modified to be at a predetermined angle with respect to the particular axis.

公开(公告)号：US20170138860A1

公开(公告)日：2017-05-18

申请号：US15322874

申请日：2015-07-02

Applicant: NATIONAL UNIVERSITY OF SINGAPORE

Inventor： Zhiwei HUANG

IPC: G01N21/65 ,  A61B5/00 ,  A61B1/018

CPC classification number: G01N21/65 ,  A61B1/018 ,  A61B5/0075 ,  A61B5/0084 ,  A61B2560/0223 ,  G01J3/0218 ,  G01J3/44 ,  G01J2003/123 ,  G01N21/274 ,  G01N2201/0612 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129

Abstract: Characterizing, identifying, or diagnosing the type and/or nature of a sample or a tissue such as an abnormal growth using a Raman spectrum includes analyzing distinct spectral subintervals within the Raman spectrum in two distinct wavelength ranges, such as FP and HW wavelength ranges, to identify a match with one or more reference markers in one or both wavelength ranges; and from the match characterizing, identifying, or diagnosing the type and/or nature of the sample or tissue. FP and HW Raman spectra can be detected or acquired simultaneously using a single diffraction grating.

公开(公告)号：US09574941B2

公开(公告)日：2017-02-21

申请号：US14122750

申请日：2012-05-30

Applicant: Arthur Nitkowski ,  Arsen Hajian

Inventor： Arthur Nitkowski ,  Arsen Hajian

IPC: G01J3/45 ,  G01J3/18 ,  G01J3/453 ,  G01J3/02

CPC classification number: G01J3/45 ,  G01J3/0218 ,  G01J3/18 ,  G01J3/4531

Abstract: A spectrometer is provided, the spectrometer having an interferometer generating an interferogram by splitting an interferometer input signal between a reference arm and a variable delay arm, and introducing a delay between the split interferometer input signals prior to interfering the split interferometer input signals. The spectrometer additionally has a controllable delay element operable to adjust the delay introduced by the interferometer and a dispersive element outputting a plurality of narrowband outputs representative of a received broadband input signal. The interferometer and dispersive element are optically connected to output a plurality of narrowband interferograms representative of a spectra of a spectrometer input signal received by the spectrometer, and the plurality of narrowband interferograms are received by a detector array for analysis.

Abstract translation: 提供了一种光谱仪，该光谱仪具有通过在参考臂和可变延迟臂之间分割干涉仪输入信号而产生干涉图的干涉仪，并且在干扰分离干涉仪输入信号之前在分离干涉仪输入信号之间引入延迟。 光谱仪还具有可控延迟元件，其可操作以调节由干涉仪引入的延迟和输出表示所接收的宽带输入信号的多个窄带输出的色散元件。 干涉仪和色散元件被光学连接以输出表示由光谱仪接收的光谱仪输入信号的光谱的多个窄带干涉图，并且多个窄带干涉图被检测器阵列接收用于分析。

公开(公告)号：US20170027447A1

公开(公告)日：2017-02-02

申请号：US15303456

申请日：2015-04-17

Applicant: THE GENERAL HOSPITAL CORPORATION

Inventor： F Jason Sutin ,  Pei-Yi Lin ,  Maria A. Franceschini

IPC: A61B5/00 ,  G01J3/02 ,  F21V8/00 ,  G02B27/09 ,  G02B5/04 ,  G01J3/10 ,  G02B5/02

CPC classification number: A61B5/0075 ,  A61B5/1455 ,  A61B2562/0233 ,  G01J3/0205 ,  G01J3/0218 ,  G01J3/10 ,  G01J3/108 ,  G02B5/0205 ,  G02B5/0278 ,  G02B5/04 ,  G02B6/001 ,  G02B27/09

Abstract: An optical probe comprising a light source providing a light that is directed along a first axis; a diffusive element positioned proximate to the light source to receive the light and to diffuse the light as it exits the diffusive element; and a directional optical element directing the light exiting the diffusive element along at least one of the first axis and a second axis generally perpendicular to the first axis to project the light out of the optical probe and onto a subject.

Abstract translation: 一种光学探头，包括提供沿第一轴指向的光的光源; 位于光源附近的扩散元件，用于接收光并使光在其离开扩散元件时漫射; 以及定向光学元件，其引导沿着所述第一轴线和大致垂直于所述第一轴线的第二轴线中的至少一个离开所述漫射元件的光，以将所述光从所述光学探针投影到被摄体上。

公开(公告)号：US20170016817A1

公开(公告)日：2017-01-19

申请号：US14799894

申请日：2015-07-15

Applicant: International Business Machines Corporation

Inventor： Tymon Barwicz ,  William M. Green ,  Yves C. Martin ,  Jason S. Orcutt ,  Lionel Tombez

IPC: G01N21/39 ,  G01N21/3504

CPC classification number: G01N21/39 ,  G01J3/0218 ,  G01J3/0256 ,  G01J3/42 ,  G01J2003/423 ,  G01N21/3504 ,  G01N21/552 ,  G01N2021/399 ,  G01N2201/06113 ,  G01N2201/063 ,  G01N2201/08 ,  G02B6/12004 ,  G02B6/12007 ,  G02B6/122 ,  G02B2006/12138 ,  G02B2006/1215

Abstract: A method of fabricating a gas sensor on a substrate and a gas sensor fabricated on a substrate that includes optical and electronic components are described. The method includes fabricating a laser to output light over a range of wavelengths within a waveguide, fabricating a splitter to split the light output by the laser to a reference waveguide and to a detection waveguide, fabricating a reference cell to house the reference waveguide and a reference gas. An output of the reference waveguide is coupled to a first optical detector and an output of the detection waveguide is coupled to a second optical detector to identify or quantify an ambient gas.

Abstract translation: 描述了在衬底上制造气体传感器的方法和制造在包括光学和电子部件的衬底上的气体传感器。 该方法包括制造激光器以在波导内的波长范围上输出光，制造分离器以将由激光器输出的光分成参考波导和检测波导，制造参考单元以容纳参考波导和 参考气体 参考波导的输出耦合到第一光学检测器，并且检测波导的输出耦合到第二光学检测器以识别或定量环境气体。

公开(公告)号：US20170010153A1

公开(公告)日：2017-01-12

申请号：US15115497

申请日：2015-01-30

Applicant: HORIBA INSTRUMENTS INCORPORATED

Inventor： Nicolas VEZARD ,  Beth FINAMORE ,  Jeremy GOLDSTONE ,  Gregoire VERRIER

IPC: G01J3/02 ,  G01J3/04 ,  G01J3/06 ,  G01J3/28 ,  G01J3/18

CPC classification number: G01J3/0229 ,  G01J3/0202 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/04 ,  G01J3/06 ,  G01J3/18 ,  G01J3/2823 ,  G01J3/36 ,  G01J2003/064 ,  G01J2003/1828

Abstract: A system and method for spectroscopic mapping, with configurable spatial resolution, of an object include a fiber optic bundle having a plurality of optical fibers arranged in a first array at an input end with each of the plurality of optical fibers spaced one from another and arranged in at least one linear array at an output end. A first mask defining a plurality of apertures equal to or greater in number than the plurality of optical fibers is positioned between an object to be imaged and the input end of the fiber optic bundle. An imaging spectrometer is positioned to receive light from the output end of the fiber optic bundle and to generate spectra of the object. A sensor associated with the imaging spectrometer converts the spectra to electrical output signals for processing by an associated computer.

Abstract translation: 具有可配置空间分辨率的对象的光谱映射的系统和方法包括具有多个光纤的光纤束，所述光纤束具有在输入端以第一阵列布置的多个光纤，所述多个光纤中的每一个彼此间隔开并布置 在输出端的至少一个线性阵列。 限定数量等于或大于多个光纤的多个孔的第一掩模位于待成像对象与光纤束的输入端之间。 成像光谱仪定位成从光纤束的输出端接收光并产生物体的光谱。 与成像光谱仪相关联的传感器将光谱转换成电输出信号以供相关计算机处理。

公开(公告)号：US20160349107A1

公开(公告)日：2016-12-01

申请号：US15114528

申请日：2014-02-21

Applicant: SHIMADZU CORPORATION ,  HONDA MOTOR CO., LTD.

Inventor： Ryoji Hiraoka ,  Nobuyuki Iwai ,  Tetsuya Nagai ,  Yasuyuki Furukawa ,  Isao Azumagakito ,  Mitsuru Kowada ,  Satoru Okada

IPC: G01J1/04 ,  G01M15/02

CPC classification number: G01J1/0425 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0289 ,  G01M15/02

Abstract: Light from a direction (D) different from a predetermined direction is reflected by a tapered surface (21) so as to enter an optical fiber (4) for guiding light entering along the predetermined direction to an appliance. Light from the desired direction (D) may thereby be reflected by the tapered surface (21) according to the angle of the tapered surface (21) and may be made to enter the optical fiber (4). Accordingly, even in a case where the installation position of an optical measurement probe (1) is limited, if the angle of the tapered surface (21) is appropriately set, light from the desired direction (D) may be made to enter the optical fiber (4).

Abstract translation: 来自与规定方向不同的方向（D）的光被锥形面（21）反射，从而进入用于引导沿规定方向进入灯具的光纤（4）。 因此，可以根据锥面（21）的角度，通过锥面（21）从所希望的方向（D）射出的光，可以进入光纤（4）。 因此，即使在光学测量探针（1）的安装位置受限的情况下，如果适当地设定锥面（21）的角度，则可以使来自期望方向（D）的光进入光学 纤维（4）。

公开(公告)号：US09500827B2

公开(公告)日：2016-11-22

申请号：US14317132

申请日：2014-06-27

Applicant: Intel Corporation

Inventor： David N. Hutchison ,  Kyu Hyun Kim ,  Haisheng Rong ,  John Heck ,  Shengbo Xu

IPC: G01J3/28 ,  G02B6/42 ,  G01J3/32 ,  G01J3/02 ,  G01J3/18

CPC classification number: G02B6/4295 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/0259 ,  G01J3/0297 ,  G01J3/1809 ,  G01J3/1895 ,  G01J3/20 ,  G01J3/32 ,  G02B6/00 ,  G02B6/12033

Abstract: Techniques and mechanisms for a monolithic photonic integrated circuit (PIC) to provide spectrometry functionality. In an embodiment, the PIC comprises a photonic device, a first waveguide and a second waveguide, wherein one of the first waveguide and the second waveguide includes a released portion which is free to move relative to a substrate of the PIC. During a metering cycle to evaluate a material under test, control logic operates an actuator to successively configure a plurality of positions of the released portion relative to the photonic device. In another embodiment, light from the first waveguide is variously diffracted by a grating of the photonic device during the metering cycle, where portions of the light are directed into the second waveguide. Different wavelengths of light diffracted into the second waveguide may be successively detected, for different positions of the released portion, to determine spectrometric measurements over a range of wavelength.

Abstract translation: 单片光子集成电路（PIC）提供光谱功能的技术和机制。 在一个实施例中，PIC包括光子器件，第一波导和第二波导，其中第一波导和第二波导中的一个包括相对于PIC的衬底自由移动的释放部分。 在用于评估被测材料的计量循环期间，控制逻辑操作致动器以相对于光子器件连续配置释放部分的多个位置。 在另一个实施例中，来自第一波导的光在计量周期期间由光子器件的光栅进行各种衍射，其中光的一部分被引导到第二波导中。 对于释放部分的不同位置，可以连续地检测衍射到第二波导中的不同波长的光，以确定波长范围上的光谱测量。

公开(公告)号：US09500634B2

公开(公告)日：2016-11-22

申请号：US14650981

申请日：2013-12-17

Applicant: OMNI MEDSCI, INC.

Inventor： Mohammed N. Islam

IPC: G01J3/00 ,  G01N33/15 ,  A61B5/1455 ,  A61B5/00 ,  G01J3/10 ,  G01J3/28 ,  G01J3/453 ,  G01N21/359 ,  A61B5/145 ,  G01N33/49 ,  H01S3/30 ,  G01J3/14 ,  G01J3/18

CPC classification number: A61B5/0088 ,  A61B5/0013 ,  A61B5/0022 ,  A61B5/0075 ,  A61B5/0086 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/4547 ,  A61B5/6801 ,  A61B5/7257 ,  A61B5/7405 ,  A61B5/742 ,  A61B2562/0233 ,  A61B2562/0238 ,  A61B2562/146 ,  A61B2576/02 ,  G01J3/0218 ,  G01J3/108 ,  G01J3/14 ,  G01J3/1838 ,  G01J3/28 ,  G01J3/2823 ,  G01J3/42 ,  G01J3/453 ,  G01J2003/104 ,  G01J2003/1208 ,  G01J2003/2826 ,  G01M3/38 ,  G01N21/35 ,  G01N21/3563 ,  G01N21/359 ,  G01N21/39 ,  G01N21/85 ,  G01N21/88 ,  G01N21/9508 ,  G01N33/02 ,  G01N33/025 ,  G01N33/15 ,  G01N33/442 ,  G01N33/49 ,  G01N2021/3595 ,  G01N2021/399 ,  G01N2201/061 ,  G01N2201/06113 ,  G01N2201/062 ,  G01N2201/08 ,  G01N2201/12 ,  G01N2201/129 ,  G06F19/00 ,  G16H40/67 ,  H01S3/0092 ,  H01S3/06758 ,  H01S3/302

Abstract: A system and method for using near-infrared or short-wave infrared (SWIR) light sources between approximately 1.4-1.8 microns, 2-2.5 microns, 1.4-2.4 microns, 1-1.8 microns for active remote sensing or hyper-spectral imaging for detection of natural gas leaks or exploration sense the presence of hydro-carbon gases such as methane and ethane. Most hydro-carbons (gases, liquids and solids) exhibit spectral features in the SWIR, which may also coincide with atmospheric transmission windows (e.g., approximately 1.4-1.8 microns or 2-2.5 microns). Active remote sensing or hyper-spectral imaging systems may include a fiber-based super-continuum laser and a detection system and may reside on an aircraft, vehicle, handheld, or stationary platform. Super-continuum sources may emit light in the near-infrared or SWIR. An imaging spectrometer or a gas-filter correlation radiometer may be used to identify substances or materials such as oil spills, geology and mineralogy, vegetation, greenhouse gases, construction materials, plastics, explosives, fertilizers, paints, or drugs.

Abstract translation: 一种使用近红外或短波红外（SWIR）光源的系统和方法，用于主动遥感或超光谱成像，大约为1.4-1.8微米，2-2.5微米，1.4-2.4微米，1-1.8微米 天然气泄漏或勘探的检测意识到甲烷和乙烷等氢碳气体的存在。 大多数碳氢化合物（气体，液体和固体）在SWIR中表现出光谱特征，这也可能与大气透射窗口（例如，约1.4-1.8微米或2-2.5微米）重合。 主动遥感或超光谱成像系统可以包括基于光纤的超连续激光器和检测系统，并且可以驻留在飞机，车辆，手持或固定平台上。 超连续光源可能在近红外或SWIR发光。 成像光谱仪或气体过滤器相关辐射计可用于识别物质或材料，如漏油，地质和矿物学，植被，温室气体，建筑材料，塑料，爆炸物，肥料，油漆或药物。

公开(公告)号：US09500588B2

公开(公告)日：2016-11-22

申请号：US14501495

申请日：2014-09-30

Applicant: PerkinElmer Health Sciences, Inc.

Inventor： Joseph L. DiCesare ,  Feng Jin ,  Timothy P. Neal ,  David Aikens

IPC: G01N21/05 ,  G01N21/59 ,  G01N21/00 ,  G01N21/64 ,  G01J3/44 ,  G01J3/10 ,  G01N21/03 ,  G01J3/02

CPC classification number: G01N21/64 ,  G01J3/0218 ,  G01J3/0221 ,  G01J3/024 ,  G01J3/4406 ,  G01J2003/104 ,  G01N21/05 ,  G01N21/645 ,  G01N2021/0314 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6463 ,  G01N2021/6482 ,  G01N2021/6484

Abstract: A liquid sample analyzer includes a liquid sample source, a flow cell, an optical device and a plurality of optical fibers. The flow cell is configured to receive a flow of a liquid sample from the liquid sample source. The plurality of optical fibers optically connect the flow cell to the optical device to transmit light between the flow cell and the optical device.

Abstract translation: 液体样品分析仪包括液体样本源，流动池，光学装置和多根光纤。 流动池被配置为从液体样品源接收液体样品的流动。 多个光纤将流动池光学地连接到光学装置，以在流动池和光学装置之间透射光。