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11 条记录 (耗时 0.055 秒)

    Turbomachine
    5.
    发明授权
    Turbomachine 失效
    涡轮机

    公开(公告)号：US4243357A

    公开(公告)日：1981-01-06

    申请号：US063669

    申请日：1979-08-06

    申请人： Patrick F. Flynn ,  Harold G. Weber ,  John M. Mulloy

    发明人： Patrick F. Flynn ,  Harold G. Weber ,  John M. Mulloy

    IPC分类号： F01D5/04 ,  F04D29/28

    CPC分类号： F01D5/043 ,  F01D5/048

    摘要： A turbomachine, operable as a compressor or a turbine, for a compressible fluid is provided which includes a wheel having a plurality of vanes extending from a generally axial flow section to a generally radial flow section. Adjacent vanes define fluid passageways having a generally axially oriented section and a generally radially oriented section. Located substantially within the generally radially oriented sections of a predetermined number of passageways is a reference station which has a configuration such that the mean tangential dimension of said passageway at said reference station is no more than about 60% of the circumference of the rotor at that mean radius divided by the number of vanes at that radius. Each reference station serves to effect substantial attachment of the flowing fluid to the surfaces defining said passageway, particularly at low mass flow, and, thus, broaden the usable flow range of the turbomachine. A rounded vane end at the wheel periphery further serves to enhance said attachment.

    摘要翻译： 提供了一种用于可压缩流体的可操作为压缩机或涡轮机的涡轮机，其包括具有从大致轴向流动部分延伸到大致径向流动部分的多个叶片的轮。 相邻的叶片限定具有大致轴向定向的部分和通常径向取向的部分的流体通道。 基本上位于预定数量的通道的通常径向定向的部分内的是具有这样一种构造的参考站，所述构造使得在所述参考站处的所述通道的平均切向尺寸不超过所述转子圆周的大约60％ 平均半径除以该半径处的叶片数。 每个参考站用于实质上将流动流体附着到限定所述通道的表面上，特别是在低质量流动下，从而扩大涡轮机的可用流量范围。 在轮周边处的圆形叶片端还用于增强所述附接。

    1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyridinyl]-butanones and related sulfoxides and sulfones
    7.
    发明授权
    1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyridinyl]-butanones and related sulfoxides and sulfones 失效
    1-（4-氟苯基）-4- [1,2,3,6-四氢-4-（苯硫基）-1-吡啶基] - 丁酮和相关的亚砜和砜

    公开(公告)号：US4218455A

    公开(公告)日：1980-08-19

    申请号：US922511

    申请日：1978-07-10

    申请人： Lawrence D. Wise ,  Patrick F. Flynn ,  Glenn C. Morrison

    发明人： Lawrence D. Wise ,  Patrick F. Flynn ,  Glenn C. Morrison

    IPC分类号： C07D211/72 ,  C07D213/70 ,  A61K31/44 ,  C07D213/04

    CPC分类号： C07D213/70 ,  C07D211/72

    摘要： Tetrahydropyridylbutyrophenones of the following formula IX: ##STR1## wherein x is hydrogen, halogen such as fluorine, chlorine, bromine or iodine, trifluoromethyl, alkoxy, nitro, cyano, amino, lower alkyl of 1 to 6 carbons, aryl or substituted aryl; y is hydrogen or halogen; and n is 0, 1 or 2; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. Tetrahydropyridylbutanols having the formula X: ##STR2## wherein x and y are as defined above, as well as their non-toxic, pharmaceutically acceptable acid addition salts, are also disclosed. The compounds of the invention having the formulas IX and X are useful as antipsychotics.

    摘要翻译： 下式IX的四氢吡啶基丁酰苯：IX其中x是氢，卤素如氟，氯，溴或碘，三氟甲基，烷氧基，硝基，氰基，氨基，1至6个碳的低级烷基，芳基或取代的芳基; y是氢或卤素; 且n为0,1或2; 和其无毒的药学上可接受的酸加成盐。 还公开了具有式X的XRD的四氢吡啶基丁醇，其中x和y如上所定义，以及它们的无毒的药学上可接受的酸加成盐。 具有式IX和X的本发明化合物可用作抗精神病药。

    Turbomachine
    9.
    发明授权
    Turbomachine 失效
    涡轮机

    公开(公告)号：US4227855A

    公开(公告)日：1980-10-14

    申请号：US936695

    申请日：1978-08-25

    申请人： Patrick F. Flynn ,  Harold G. Weber ,  John M. Mulloy

    发明人： Patrick F. Flynn ,  Harold G. Weber ,  John M. Mulloy

    IPC分类号： F01D5/04 ,  F04D29/28

    CPC分类号： F01D5/043 ,  F01D5/048 ,  F04D29/284

    摘要： A turbomachine for a compressible fluid is provided which includes a compressor wheel having a plurality of vanes extending from a generally axial flow inlet to a generally radial flow outlet. Adjacent vanes define fluid passageways having a generally axially oriented section near the inlet and a generally radially oriented section near the outlet. Located substantially within the generally radially oriented sections of a predetermined number of passageways is a reference station which has a configuration such that the mean tangential dimension of said passageway at said reference station is no more than about 60% of the circumference of the rotor at that mean radius divided by the number of vanes at that radius. Each reference station serves to effect substantial attachment of the flowing fluid to the surfaces defining said passageway, particularly at low mass flow, and, thus, broaden the usable flow range of the compressor.

    摘要翻译： 提供了一种用于可压缩流体的涡轮机，其包括具有多个叶片的压缩机叶轮，所述多个叶片从大致轴向的流动入口延伸到大致径向的流动出口。 相邻的叶片限定在入口附近具有大致轴向定向的部分的流体通道和靠近出口的大致径向定向的部分。 基本上位于预定数量的通道的通常径向定向的部分内的是具有这样一种构造的参考站，所述构造使得在所述参考站处的所述通道的平均切向尺寸不超过所述转子圆周的大约60％ 平均半径除以该半径处的叶片数。 每个参考站用于实质上将流动的流体附着到限定所述通道的表面，特别是在低质量流动下，从而扩大压缩机的可用流量范围。

    1-(4-Fluorophenyl)-4-(1,2,3,6-tetrahydro-4-phenoxy-1-pyridinyl)-butanones
    10.
    发明授权
    1-(4-Fluorophenyl)-4-(1,2,3,6-tetrahydro-4-phenoxy-1-pyridinyl)-butanones 失效
    1-（4-氟苯基）-4-（1,2,3,6-四氢-4-苯氧基-1-吡啶基） - 丁酮

    公开(公告)号：US4218456A

    公开(公告)日：1980-08-19

    申请号：US922512

    申请日：1978-07-10

    申请人： Lawrence D. Wise ,  Patrick F. Flynn ,  Glenn C. Morrison

    发明人： Lawrence D. Wise ,  Patrick F. Flynn ,  Glenn C. Morrison

    IPC分类号： C07D211/74 ,  A61K31/44 ,  C07D213/04

    CPC分类号： C07D211/74

    摘要： Tetrahydropyridylbutyrophenones of the following formula I: ##STR1## wherein x is hydrogen, halogen such as fluorine, chlorine, bromine or iodine, trifluoromethyl, alkoxy, thioalkoxy, nitro, cyano, amino, lower alkyl of 1 to 6 carbons, aryl or substituted aryl; and y is hydrogen or halogen; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. The compounds of the invention having the formula I are useful in the treatment of psychotic disorders such as schizophrenia.

    摘要翻译： 下式I的四氢吡啶基丁酰苯：其中x是氢，卤素如氟，氯，溴或碘，三氟甲基，烷氧基，硫代烷氧基，硝基，氰基，氨基，1-6个碳的低级烷基，芳基或取代 芳基; 和y是氢或卤素; 和其无毒的药学上可接受的酸加成盐。 具有式I的本发明化合物可用于治疗精神病如精神分裂症。