公开(公告)号：US20070119711A1

公开(公告)日：2007-05-31

申请号：US11698363

申请日：2007-01-25

申请人： Walter Ausserer ,  Luc Bousse ,  Robert Dubrow ,  Steven Sundberg ,  Andrea Chow ,  Benjiamin Wang

发明人： Walter Ausserer ,  Luc Bousse ,  Robert Dubrow ,  Steven Sundberg ,  Andrea Chow ,  Benjiamin Wang

IPC分类号： C07K1/26 ,  G01N27/00

CPC分类号： C07K1/26 ,  G01N27/447

摘要： Methods and systems for use in separating sample materials into different fractions employing pressure-based fluid flow for simultaneous loading of a sample and a reagent into a sample loading channel of a microfluidic device. The sample is loaded from an external source through an attached external sampling capillary. The reagent, which may be a molecular weight standard, a diluent, a detergent, or a labeling reagent, is loaded from a reservoir integral to the microfluidic device via a reagent introduction channel within the device. The sample and reagent form a mixture in the sample loading channel. A portion of the mixture is electrokinetically injected from the sample loading channel, via an injection channel, into a separation channel, where it is separated electrophoretically.

摘要翻译： 用于将样品材料分离成不同级分的方法和系统，其使用基于压力的流体流将样品和试剂同时装载到微流体装置的样品加载通道中。 样品通过附带的外部取样毛细管从外部来源加载。 可以是分子量标准的试剂，稀释剂，洗涤剂或标记试剂，通过装置内的试剂引入通道从集成在微流体装置中的储存器装载。 样品和试剂在样品加载通道中形成混合物。 将混合物的一部分从样品加载通道经由注射通道电动注射到分离通道中，其中电泳分离。

公开(公告)号：US20060258019A1

公开(公告)日：2006-11-16

申请号：US11461163

申请日：2006-07-31

申请人： Andrea Chow ,  Anne Kopf-Sill ,  J. Parce ,  Robert Dubrow

发明人： Andrea Chow ,  Anne Kopf-Sill ,  J. Parce ,  Robert Dubrow

IPC分类号： B01L3/00

CPC分类号： B01D61/18 ,  B01L3/5025 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/50273 ,  B01L2200/027 ,  B01L2300/0861 ,  B01L2300/0867 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/043 ,  B01L2400/0457 ,  Y10T137/2496 ,  Y10T137/2499 ,  Y10T137/2501 ,  Y10T137/2514 ,  Y10T137/2516 ,  Y10T436/11 ,  Y10T436/2575

摘要： Methods and devices for delivering fluids into microfluidic device body structures are described. The methods and devices include the use of fluid manifolds that are integrated or interchangeable with device body structures. Methods of fabricating manifolds are also provided.

摘要翻译： 描述了将流体输送到微流体装置体结构中的方法和装置。 所述方法和装置包括使用与装置主体结构集成或可互换的流体歧管。 还提供制造歧管的方法。

公开(公告)号：US20090143227A1

公开(公告)日：2009-06-04

申请号：US11331445

申请日：2006-01-11

申请人： Robert Dubrow ,  Carlos Guillermo Casillas ,  William P. Freeman ,  Jay L. Goldman ,  Veeral Dilip Hardev ,  Francisco Leon ,  Chunming Niu ,  Cheri X. Y. Pereira

发明人： Robert Dubrow ,  Carlos Guillermo Casillas ,  William P. Freeman ,  Jay L. Goldman ,  Veeral Dilip Hardev ,  Francisco Leon ,  Chunming Niu ,  Cheri X. Y. Pereira

IPC分类号： B01J20/20 ,  B01J20/02

CPC分类号： B01D39/083 ,  B01D39/086 ,  B01D39/2065 ,  B01D2239/0208 ,  B01D2239/0216 ,  B01D2239/025 ,  B01D2239/0407 ,  B01D2239/0421 ,  B01D2239/0428 ,  B01D2239/0492 ,  B01D2239/064 ,  B01D2239/065 ,  B01D2239/0654 ,  B01D2239/10 ,  B01D2239/1216 ,  B01D2239/1225 ,  B82Y30/00 ,  D06M11/44 ,  D06M11/45 ,  D06M11/46 ,  D06M11/49 ,  D06M11/83 ,  G01N30/52 ,  Y10S977/742 ,  Y10S977/749 ,  Y10S977/753

摘要： Porous and/or curved nanofiber bearing substrate materials are provided having enhanced surface area for a variety of applications including as electrical substrates, semipermeable membranes and barriers, structural lattices for tissue culturing and for composite materials, production of long unbranched nanofibers, and the like.

摘要翻译： 提供了多孔和/或弯曲的纳米纤维轴承基材，其具有用于各种应用的增强的表面积，包括作为电基底，半透膜和屏障，用于组织培养的结构晶格和用于复合材料的结构晶格，长非支化纳米纤维的生产等。

公开(公告)号：US07344617B2

公开(公告)日：2008-03-18

申请号：US11374906

申请日：2006-03-14

申请人： Robert Dubrow

发明人： Robert Dubrow

IPC分类号： B32B37/00

CPC分类号： B81C3/008 ,  A61B17/00 ,  A61B17/00491 ,  B82Y30/00 ,  C09J5/00 ,  C09J7/00 ,  C09J2201/626 ,  C09J2400/123 ,  H01L23/373 ,  H01L2924/0002 ,  H01L2924/09701 ,  Y10S977/762 ,  Y10S977/766 ,  Y10S977/902 ,  Y10S977/931 ,  Y10S977/962 ,  Y10S977/963 ,  Y10T156/10 ,  Y10T428/23993 ,  Y10T428/24008 ,  Y10T428/26 ,  Y10T428/2913 ,  Y10T428/2922 ,  Y10T428/2925 ,  H01L2924/00

摘要： This invention provides novel nanofibers and nanofiber structures which posses adherent properties, as well as the use of such nanofibers and nanofiber comprising structures in the coupling and/or joining together of articles or material.

摘要翻译： 本发明提供了新颖的纳米纤维和纳米纤维结构，其具有粘附性能，以及在物品或材料的联接和/或连接在一起的这种纳米纤维和纳米纤维包含结构的用途。

公开(公告)号：US20060165952A1

公开(公告)日：2006-07-27

申请号：US11374906

申请日：2006-03-14

申请人： Robert Dubrow

发明人： Robert Dubrow

IPC分类号： B32B3/06 ,  B32B37/00

CPC分类号： B81C3/008 ,  A61B17/00 ,  A61B17/00491 ,  B82Y30/00 ,  C09J5/00 ,  C09J7/00 ,  C09J2201/626 ,  C09J2400/123 ,  H01L23/373 ,  H01L2924/0002 ,  H01L2924/09701 ,  Y10S977/762 ,  Y10S977/766 ,  Y10S977/902 ,  Y10S977/931 ,  Y10S977/962 ,  Y10S977/963 ,  Y10T156/10 ,  Y10T428/23993 ,  Y10T428/24008 ,  Y10T428/26 ,  Y10T428/2913 ,  Y10T428/2922 ,  Y10T428/2925 ,  H01L2924/00

摘要： This invention provides novel nanofibers and nanofiber structures which posses adherent properties, as well as the use of such nanofibers and nanofiber comprising structures in the coupling and/or joining together of articles or material.

摘要翻译： 本发明提供了新颖的纳米纤维和纳米纤维结构，其具有粘附性能，以及在物品或材料的联接和/或连接在一起的这种纳米纤维和纳米纤维包含结构的用途。

公开(公告)号：US08592037B2

公开(公告)日：2013-11-26

申请号：US13277361

申请日：2011-10-20

申请人： J. Wallace Parce ,  Paul Bernatis ,  Robert Dubrow ,  William P Freeman ,  Joel Gamoras ,  Shihai Kan ,  Andreas Meisel ,  Baixin Qian ,  Jeffery A Whiteford ,  Jonathan Ziebarth

发明人： J. Wallace Parce ,  Paul Bernatis ,  Robert Dubrow ,  William P Freeman ,  Joel Gamoras ,  Shihai Kan ,  Andreas Meisel ,  Baixin Qian ,  Jeffery A Whiteford ,  Jonathan Ziebarth

IPC分类号： B32B9/04

CPC分类号： C09K11/02 ,  B82Y20/00 ,  B82Y30/00 ,  C01B19/007 ,  C01G9/08 ,  C01P2002/72 ,  C01P2002/84 ,  C01P2004/04 ,  C01P2004/64 ,  C01P2004/80 ,  C01P2004/84 ,  C09K11/565 ,  C09K11/70 ,  C09K11/883 ,  G02B1/11 ,  G02B3/0087 ,  G02B2207/101 ,  H01L33/502 ,  Y10S977/783

摘要： Compositions containing a nanostructure, preferably a nanocrystal, are provided. The nanostructures have ligands bound to the surface. Such ligands are preferably siloxane containing ligands having at least one —COON group, although ligands having various ═P═O groups are also contemplated. The nanostructures can be embedded into a polymer such as a silicone polymer.

摘要翻译： 提供了包含纳米结构，优选纳米晶体的组合物。 纳米结构具有与表面结合的配体。 这样的配体优选是具有至少一个-COON基团的含硅氧烷的配位体，尽管也考虑了具有各种= P = O基团的配位体。 纳米结构可以嵌入到聚合物如硅氧烷聚合物中。

公开(公告)号：US20100075468A1

公开(公告)日：2010-03-25

申请号：US11507631

申请日：2006-08-21

申请人： Robert Dubrow ,  Linda T. Romano ,  David Stumbo

发明人： Robert Dubrow ,  Linda T. Romano ,  David Stumbo

IPC分类号： H01L21/336 ,  H01L21/20

CPC分类号： H01L21/02422 ,  B82Y10/00 ,  B82Y20/00 ,  B82Y30/00 ,  C30B7/00 ,  H01L21/02381 ,  H01L21/02521 ,  H01L21/02603 ,  H01L21/02656 ,  Y10S977/762 ,  Y10S977/827

摘要： Methods and systems for depositing nanomaterials onto a receiving substrate and optionally for depositing those materials in a desired orientation, that comprise providing nanomaterials on a transfer substrate and contacting the nanomaterials with an adherent material disposed upon a surface or portions of a surface of a receiving substrate. Orientation is optionally provided by moving the transfer and receiving substrates relative to each other during the transfer process.

摘要翻译： 用于将纳米材料沉积到接收衬底上并且任选地用于以期望取向沉积那些材料的方法和系统，其包括在转移衬底上提供纳米材料并使纳米材料与设置在接收衬底的表面或表面的部分上的粘附材料接触 。 可选地通过在传送过程中相对于彼此移动传送和接收基板来提供取向。

公开(公告)号：US20080038520A1

公开(公告)日：2008-02-14

申请号：US11641939

申请日：2006-12-20

申请人： Yaoling Pan ,  Xiangfeng Duan ,  Robert Dubrow ,  Jay Goldman ,  Shahriar Mostarshed ,  Chunming Niu ,  Linda Romano ,  David Stumbo ,  Alice Fischer-Colbrie ,  Vijendra Sahi ,  Virginia Robbins

发明人： Yaoling Pan ,  Xiangfeng Duan ,  Robert Dubrow ,  Jay Goldman ,  Shahriar Mostarshed ,  Chunming Niu ,  Linda Romano ,  David Stumbo ,  Alice Fischer-Colbrie ,  Vijendra Sahi ,  Virginia Robbins

IPC分类号： B32B15/02 ,  B05D5/12

CPC分类号： C30B29/605 ,  B82Y30/00 ,  C30B11/12 ,  C30B29/06 ,  Y10T428/24917

摘要： The present invention is directed to systems and methods for nanowire growth and harvesting. In an embodiment, methods for nanowire growth and doping are provided, including methods for epitaxial oriented nanowire growth using a combination of silicon precursors, as well as us of patterned substrates to grow oriented nanowires. In a further aspect of the invention, methods to improve nanowire quality through the use of sacrifical growth layers are provided. In another aspect of the invention, methods for transferring nanowires from one substrate to another substrate are provided.

公开(公告)号：US20060279905A1

公开(公告)日：2006-12-14

申请号：US11507267

申请日：2006-08-21

申请人： Calvin Chow ,  Robert Dubrow

发明人： Calvin Chow ,  Robert Dubrow

IPC分类号： H01G9/04 ,  H01G9/145

CPC分类号： H01G4/008 ,  H01G4/005 ,  H01G4/06 ,  H01G4/203 ,  H01G4/33 ,  H01G9/04 ,  H01G11/36 ,  H01G11/46 ,  H01L28/82 ,  H05K1/162 ,  H05K2201/026 ,  Y02E60/13

摘要： This invention provides novel capacitors comprising nanofiber enhanced surface area substrates and structures comprising such capacitors, as well as methods and uses for such capacitors.

公开(公告)号：US20060204738A1

公开(公告)日：2006-09-14

申请号：US11330722

申请日：2006-01-12

申请人： Robert Dubrow ,  Lawrence Bock ,  R. Daniels ,  Veeral Hardev ,  Chunming Niu ,  Vijendra Sahi

发明人： Robert Dubrow ,  Lawrence Bock ,  R. Daniels ,  Veeral Hardev ,  Chunming Niu ,  Vijendra Sahi

IPC分类号： D04H13/00

CPC分类号： A61L31/10 ,  A61F13/02 ,  A61L27/34 ,  A61L2400/12 ,  A61L2420/04 ,  A61N1/05 ,  B82Y30/00 ,  Y10S977/762 ,  Y10S977/764 ,  Y10S977/773 ,  Y10S977/811 ,  Y10S977/813 ,  Y10S977/90 ,  Y10S977/904 ,  Y10S977/906 ,  Y10T428/12111 ,  Y10T428/249924 ,  Y10T428/29

摘要： This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such substrates and medical devices. In one particular embodiment, methods for enhancing cellular functions on a surface of a medical device implant are disclosed which generally comprise providing a medical device implant comprising a plurality of nanofibers (e.g., nanowires) thereon and exposing the medical device implant to cells such as osteoblasts.