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    MULTI-FUNCTIONAL SURFACE COATING OF IMPLANTS
    5.
    发明申请
    MULTI-FUNCTIONAL SURFACE COATING OF IMPLANTS 审中-公开
    多功能表面涂层

    公开(公告)号：US20150320913A1

    公开(公告)日：2015-11-12

    申请号：US14646723

    申请日：2013-11-24

    申请人： UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL

    发明人： Jie Song ,  Pingsheng Liu ,  David C. Ayers

    IPC分类号： A61L31/10 ,  A61L29/16 ,  A61L29/08 ,  A61L27/54 ,  C08F122/10 ,  A61L31/02 ,  A61L29/02 ,  A61L27/06 ,  C08F222/10 ,  A61L31/16 ,  A61L27/34

    CPC分类号： A61L27/04 ,  A61L27/06 ,  A61L27/34 ,  A61L27/54 ,  A61L29/02 ,  A61L29/085 ,  A61L29/16 ,  A61L31/022 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/404 ,  A61L2300/406 ,  A61L2300/606 ,  A61L2300/80 ,  C08F122/10 ,  C08F222/10 ,  C08F293/005 ,  C08F2220/387 ,  C09D133/08

    摘要： The invention provides novel surface coatings having surface polymer brushes with zwitterionic and antibiotics-conjugated side chains and synergistic anti-fouling and bactericidal properties. The surface coatings may be prepared using highly efficient surface-initiated “living” polymerization. The design of the surface polymer brushes are highly modular, allowing independent tuning of the anti-fouling and bactericidal properties, e.g., by varying the chemical nature of the zwitterionic motif and the antibiotic agent, the chemistry through which the antibiotic agent is conjugated to the polymer side chains, the molecular weight of the polymer brushes (e.g., thickness of coating and density of respective functional motifs), and the spatial arrangement of the respective functional motifs (e.g., homopolymers, block copolymers, random copolymers) to achieve optimal and sustained anti-infection outcome for a given application.

    摘要翻译： 本发明提供具有表面聚合物刷的新型表面涂层，其具有两性离子和抗生素缀合的侧链和协同的抗结垢和杀菌性质。 表面涂层可以使用高效的表面引发的“活性”聚合来制备。 表面聚合物刷的设计是高度模块化的，允许独立调节抗污垢和杀菌性能，例如通过改变两性离子基序和抗生素剂的化学性质，抗生素试剂与其结合的化学性质 聚合物侧链，聚合物刷子的分子量（例如，涂层的厚度和相应功能基序的密度）以及相应功能基序（例如均聚物，嵌段共聚物，无规共聚物）的空间排列以实现最佳和持续的 针对给定应用的抗感染结果。

    Optical composition
    8.
    发明授权
    Optical composition 有权
    光学组成

    公开(公告)号：US09556292B2

    公开(公告)日：2017-01-31

    申请号：US14440710

    申请日：2013-12-17

    申请人： PHILIPS LIGHTING HOLDING B.V.

    发明人： Rifat Ata Mustafa Hikmet ,  Ties Van Bommel

    IPC分类号： C08K3/30 ,  C08F122/10 ,  G02B1/04 ,  C08G77/398 ,  H01L33/58 ,  C08L83/04 ,  B82Y30/00 ,  B82Y20/00

    CPC分类号： C08F122/10 ,  B82Y20/00 ,  B82Y30/00 ,  C08G77/398 ,  C08K3/30 ,  C08L83/04 ,  G02B1/04 ,  H01L33/58

    摘要： The present invention aims to reduce excess scattering in light emitting arrangements. A composition comprising a transparent matrix comprising an anionic organic moiety, and metal cations dispersed in the matrix is disclosed. The anionic organic moiety and the metal cations form an organometallic complex, and wherein the metal cations are capable of forming transparent nano-crystals upon contact with an agent comprising at least one element selected from the group consisting of sulfur and selenium. Also an optical composition comprising a transparent matrix comprising an organic moiety residue, and unmodified nanocrystals is disclosed. Further, a method of preparing an optical composition comprising the steps of: providing a transparent matrix comprising an anionic organic moiety; dispersing metal cations into the matrix; and contacting the organometallic complex with an agent in order to in situ convert at least part of the metal cations into transparent nanocrystals.Preferably the matrix is a silicone or a polysiloxane and silicone rubber mixture.

    摘要翻译： 优选地，基质是硅氧烷或聚硅氧烷和硅橡胶混合物。

    POLYMER NANOPARTICLES
    10.
    发明申请
    POLYMER NANOPARTICLES 审中-公开
    聚合物纳米粒子

    公开(公告)号：US20160024241A1

    公开(公告)日：2016-01-28

    申请号：US14872148

    申请日：2015-10-01

    申请人： ETH ZUERICH

    发明人： HANSJOERG GRUETZMACHER ,  TIMO OTT

    IPC分类号： C08F228/02 ,  C07F9/6506 ,  C08F222/30 ,  C08F122/10 ,  C08F112/08 ,  C08F212/08 ,  C07F9/53 ,  C07F9/59

    CPC分类号： C08F228/02 ,  C07F9/5036 ,  C07F9/5045 ,  C07F9/5337 ,  C07F9/59 ,  C07F9/6506 ,  C08F2/24 ,  C08F2/50 ,  C08F112/08 ,  C08F122/10 ,  C08F212/08 ,  C08F222/30

    摘要： A process for the preparation of a polymer nanoparticle by a photoinduced emulsion polymerization includes preparing an emulsion comprising at least one surfactant, a dispersed phase and a continuous phase. The dispersed phase comprises at least one polymerizable monomer and the continuous phase comprises water and at least one photoinitiator. The at least one polymerizable monomer is polymerized by exposing the emulsion to an electromagnetic radiation having a wavelength so as to induce a generation of radicals from the at least one photoinitiator. The at least one photoinitiator is selected from at least one compound of formula (I)

    摘要翻译： 通过光诱导乳液聚合制备聚合物纳米颗粒的方法包括制备包含至少一种表面活性剂，分散相和连续相的乳液。 分散相包含至少一种可聚合单体，连续相包含水和至少一种光引发剂。 通过将乳液暴露于具有波长的电磁辐射以使所述至少一种光引发剂产生自由基来聚合所述至少一种可聚合单体。 所述至少一种光引发剂选自至少一种式（I）化合物，