公开(公告)号：US10076283B2

公开(公告)日：2018-09-18

申请号：US14539437

申请日：2014-11-12

Applicant: Medtronic, Inc.

Inventor： Orhan Soykan ,  Christopher M. Hobot ,  Martin T. Gerber ,  VenKatesh R. Manda

IPC: A61M37/00 ,  A61B5/00 ,  A61B5/0205 ,  A61M1/34 ,  A61M1/16 ,  A61M1/28 ,  A61B5/021 ,  A61B5/024 ,  A61B5/046 ,  A61B5/053 ,  A61B5/08 ,  A61B5/1455 ,  A61B5/20 ,  G06F19/00 ,  G16H50/20 ,  G16H50/50

CPC classification number: A61B5/7246 ,  A61B5/0205 ,  A61B5/021 ,  A61B5/02405 ,  A61B5/046 ,  A61B5/053 ,  A61B5/08 ,  A61B5/14552 ,  A61B5/201 ,  A61B5/4806 ,  A61B5/4848 ,  A61B5/4875 ,  A61B5/7264 ,  A61M1/1603 ,  A61M1/282 ,  A61M1/3403 ,  A61M2205/3523 ,  G06F19/00 ,  G06F19/3481 ,  G16H20/40 ,  G16H50/20 ,  G16H50/50

Abstract: A system and method for determining the amount of fluid to be removed from a dialysis patient is disclosed. The system utilizes sensors and a computer. The computer obtains the input parameters from the sensors, along with information added directly by the user, and performs a forward algorithm to determine a recommended change in patient fluid level. As fluid is removed, the effect of the removal on the parameters is detected by the sensors and re-transmitted back to the computer. The computer then performs a backward algorithm to refine the variables used in the forward algorithm and obtain more accurate results. The system and method provide for changing the amount of fluid removed from the patient based on the results of the algorithm and the data received from the sensors.

公开(公告)号：US10016553B2

公开(公告)日：2018-07-10

申请号：US14633852

申请日：2015-02-27

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Christopher M. Hobot

IPC: B01D24/00 ,  A61M1/16 ,  B01D35/00

CPC classification number: A61M1/1696

Abstract: An apparatus and method for replenishing urease in a sorbent cartridge for use in sorbent dialysis. The sorbent cartridge is configured to allow an amount of urease to be added to the sorbent cartridge. A urease solution can be injected into the sorbent cartridge to replenish the urease containing module, or solid urease can be added to the sorbent cartridge. The sorbent module can also comprise other, rechargeable, sorbent materials for removing toxins other than urea from spent dialysate.

公开(公告)号：US20180126055A1

公开(公告)日：2018-05-10

申请号：US15865311

申请日：2018-01-09

Applicant: Medtronic, Inc.

Inventor： Bryant J. PUDIL ,  Martin T. Gerber ,  David B. Lura ,  Thomas E. Meyer

IPC: A61M1/14 ,  A61M1/16 ,  B01J39/12 ,  B01J20/06 ,  B01J20/02 ,  B01J20/20

Abstract: A detachable module for optionally recharging sorbent materials, including zirconium phosphate, with an optional bypass and conduits for a sorbent cartridge. The sorbent cartridge can have one or more modules contained therein having connectors connecting each of the modules. One or more of the modules can be reusable and the sorbent materials therein recharged.

公开(公告)号：US20180043081A1

公开(公告)日：2018-02-15

申请号：US15723764

申请日：2017-10-03

Applicant: Medtronic, Inc.

Inventor： David B. Lura ,  Martin T. Gerber ,  Christopher M. Hobot ,  Thomas E. Meyer

IPC: A61M1/28 ,  A61M1/16 ,  A61M39/22

CPC classification number: A61M1/282 ,  A61L2/10 ,  A61M1/1605 ,  A61M1/1656 ,  A61M1/1666 ,  A61M1/1672 ,  A61M1/1674 ,  A61M1/1686 ,  A61M1/28 ,  A61M1/287 ,  A61M39/22 ,  A61M2205/18 ,  A61M2205/3331 ,  A61M2205/3368 ,  A61M2205/50 ,  A61M2205/502 ,  A61M2205/75 ,  A61M2205/7518 ,  A61M2209/084 ,  A61M2209/10 ,  C02F1/008 ,  C02F1/281 ,  C02F1/283 ,  C02F1/325 ,  C02F1/42 ,  C02F1/441 ,  C02F1/442 ,  C02F1/444 ,  C02F9/00 ,  C02F2103/026 ,  C02F2103/04 ,  C02F2209/03 ,  C02F2209/40 ,  C02F2303/04

Abstract: The invention relates to devices, systems, and methods for generating a peritoneal dialysate having purity and sterility characteristics suitable for Peritoneal Dialysis (PD). The peritoneal dialysate can be generated from water of variable quality using a purity control system having one or more ultrafilters for sterilization of the peritoneal dialysate Peritoneal dialysate generation system and related methods are described that can generate sterilized peritoneal dialysate and deliver peritoneal dialysis therapy to a patient.

公开(公告)号：US20180036530A1

公开(公告)日：2018-02-08

申请号：US15782272

申请日：2017-10-12

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber ,  Steven M. Goetz ,  Christopher Poletto

IPC: A61N1/36

CPC classification number: A61N1/36 ,  A61N1/36057 ,  A61N1/36075 ,  A61N1/36082 ,  A61N1/36132

Abstract: Prophylactic stimulation and abortive electrical stimulation are delivered to a cranial nerve, including, e.g. an occipital or trigeminal nerve to treat symptoms of various conditions, including, e.g. occipital neuralgia or migraines.

公开(公告)号：US09855379B2

公开(公告)日：2018-01-02

申请号：US14828853

申请日：2015-08-18

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Thomas E. Meyer ,  David B. Lura ,  Martin T. Gerber

IPC: A61M1/16 ,  A61M1/34 ,  B01D15/08 ,  A61M1/28

CPC classification number: A61M1/1656 ,  A61M1/1654 ,  A61M1/1668 ,  A61M1/167 ,  A61M1/1696 ,  A61M1/287 ,  A61M1/3486 ,  A61M2205/02 ,  B01D15/08

Abstract: A regeneration system that has a first regeneration module containing a first chosen regenerative substance; a second regeneration module containing the first chosen regenerative substance; and a first mixing chamber. A first outlet stream of a fluid sequentially exits the first mixing chamber, flows through the first regeneration module in fluid communication with the first chosen regenerative substance and returns to the first mixing chamber, and a second outlet stream of the fluid sequentially exits the first mixing chamber and flows through the second regeneration module in fluid communication with the first chosen regenerative substance.

公开(公告)号：US20170333698A1

公开(公告)日：2017-11-23

申请号：US15668793

申请日：2017-08-04

Applicant: MEDTRONIC, INC.

Inventor： Martin T. Gerber ,  Michael D. Baudino

IPC: A61N1/05 ,  A61N1/04

CPC classification number: A61N1/0531 ,  A61B17/00 ,  A61B17/3468 ,  A61N1/048 ,  A61N1/05 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/056 ,  A61N1/0573 ,  A61N1/0587 ,  A61N1/0592

Abstract: Introducers for implanting a lead having a fixation element distal to an electrode include a window, electrode, or conductive member alignable with the electrode of the lead while maintaining the fixation element in a retracted configuration. The window, electrode or conductive member of the introducer provide a mechanism for applying test stimulation signals to determine whether the lead is properly positioned in a patient without deploying the fixation element.

公开(公告)号：US20170281932A1

公开(公告)日：2017-10-05

申请号：US15589700

申请日：2017-05-08

Applicant: Medtronic, Inc.

Inventor： Martin T. Gerber

IPC: A61N1/05

CPC classification number: A61N1/0558 ,  A61N1/057

Abstract: The disclosure is directed to securing electrodes of a medical lead adjacent to a target tissue site. The medical lead may include at least one adhesive element disposed along a longitudinal outer surface of the lead body to adhere the adjacent tissue to the lead. Adhesive elements may be disposed proximal to, distal to, or in-between the electrodes of the lead. Each adhesive element may be inactive during lead implantation and activated by removing a covering sheath to expose the adhesive elements to moisture in the tissue or presenting an energy, e.g. ultraviolet light, to the adhesive elements. Once active, the adhesive elements secure the lead to surrounding tissue to prevent migration of the electrodes from the target tissue.

公开(公告)号：US20170239410A1

公开(公告)日：2017-08-24

申请号：US15588772

申请日：2017-05-08

Applicant: Medtronic, Inc.

Inventor： David B. Lura ,  Martin T. Gerber ,  Christopher M. Hobot ,  Thomas E. Meyer ,  Jin Huang

IPC: A61M1/16 ,  A61K33/00 ,  A61M1/34

Abstract: The invention relates to an infusate frame for use in dialysis. The infusate frame includes one or more openings cut-out of a rigid support frame. The one or more openings are sized and shaped complementary to one or more infusate containers, ensuring that only a single infusate container can occupy a specific opening.

公开(公告)号：US09707328B2

公开(公告)日：2017-07-18

申请号：US13791755

申请日：2013-03-08

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  Thomas E. Meyer ,  David B. Lura ,  Martin T. Gerber

IPC: B01D15/08 ,  B01D15/36 ,  B01J20/02 ,  B01J20/20 ,  A61M1/16 ,  A61M1/28 ,  A61M1/34 ,  B01J39/10 ,  B01J39/12 ,  B01J39/18 ,  B01J41/10 ,  B01J41/12 ,  B01J47/026 ,  B01J47/14 ,  B01J20/04 ,  B01J20/06 ,  B01J20/08 ,  B01J20/28 ,  B01J47/012

CPC classification number: A61M1/1696 ,  A61M1/284 ,  A61M1/287 ,  A61M1/288 ,  A61M1/3413 ,  A61M1/3472 ,  A61M1/3679 ,  A61M2205/3303 ,  A61M2205/3317 ,  A61M2205/3334 ,  A61M2205/50 ,  B01D15/08 ,  B01D15/361 ,  B01J20/0292 ,  B01J20/048 ,  B01J20/06 ,  B01J20/08 ,  B01J20/20 ,  B01J20/28052 ,  B01J39/10 ,  B01J39/12 ,  B01J39/18 ,  B01J41/10 ,  B01J41/12 ,  B01J47/012 ,  B01J47/026 ,  B01J47/14 ,  B01J2220/49

Abstract: A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer.