公开(公告)号：US09632066B2

公开(公告)日：2017-04-25

申请号：US14682837

申请日：2015-04-09

申请人： UT-Battelle, LLC

发明人： Gary J Van Berkel

IPC分类号： G01N30/72 ,  H01J49/04 ,  G01N30/02

CPC分类号： G01N30/7233 ,  A61B5/44 ,  A61B5/443 ,  A61B5/4845 ,  A61B10/02 ,  G01N1/00 ,  G01N1/20 ,  G01N35/1095 ,  G01N2001/028 ,  G01N2001/045 ,  G01N2030/027 ,  H01J49/0404 ,  H01J49/0431

摘要： A system for sampling a sample material includes a probe which can have an outer probe housing with an open end. A liquid supply conduit within the housing has an outlet positioned to deliver liquid to the open end of the housing. The liquid supply conduit can be connectable to a liquid supply for delivering liquid at a first volumetric flow rate to the open end of the housing. A liquid exhaust conduit within the housing is provided for removing liquid from the open end of the housing. A liquid exhaust system can be provided for removing liquid from the liquid exhaust conduit at a second volumetric flow rate, the first volumetric flow rate exceeding the second volumetric flow rate, wherein liquid at the open end will receive sample, liquid containing sample material will be drawn into and through the liquid exhaust conduit, and liquid will overflow from the open end.

公开(公告)号：US09625358B2

公开(公告)日：2017-04-18

申请号：US14342954

申请日：2012-09-04

申请人： Prakash Sreedhar Murthy ,  Akira Imai

发明人： Prakash Sreedhar Murthy ,  Akira Imai

IPC分类号： G01N1/02 ,  G01N1/22 ,  G01N15/06 ,  G01N27/62

CPC分类号： G01N1/2202 ,  G01N1/2226 ,  G01N15/06 ,  G01N27/622 ,  G01N27/624 ,  G01N2001/024 ,  G01N2001/028 ,  G01N2001/2229 ,  G01N2001/2241 ,  G01N2001/2285

摘要： There is provided a monitoring apparatus including a gas sampling apparatus and a sensor that detects a chemical substance included in gas obtained by the gas sampling apparatus. The gas sampling apparatus includes: an air supplying unit that forms an air curtain to form a space that covers a region to which an object to be monitored is included and which is separated from the outside environment; a sampling unit that extracts the gas inside the separated space; and a diffusion gas supplying unit that supplies, into the separated space, an amount of diffusion gas that is at least equal to the sampled amount of the sampling unit, wherein the sampling unit includes a plurality of sampling nozzles disposed at three-dimensionally different positions inside the separated space.

公开(公告)号：US09623409B2

公开(公告)日：2017-04-18

申请号：US15336735

申请日：2016-10-27

申请人： CUE INC.

发明人： Ayub Khattak ,  Clinton Sever ,  Paul Nelson ,  Ryan Cooper ,  Thomas Congdon ,  Justin Demartino ,  Raphael Shapiro ,  Mark Duncan

IPC分类号： G01N31/22 ,  B01L3/00 ,  B01L7/00 ,  B05D3/00 ,  C12Q1/68 ,  F16K99/00 ,  G01N27/28 ,  G01N27/327 ,  G01N33/543 ,  G01N33/58 ,  G01N35/00 ,  H04M1/725 ,  G01N1/02 ,  G01N21/78 ,  G01N35/10

CPC分类号： B01L3/508 ,  B01F11/0266 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/502723 ,  B01L3/502738 ,  B01L3/5029 ,  B01L7/52 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/027 ,  B01L2200/028 ,  B01L2200/0668 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2200/087 ,  B01L2200/10 ,  B01L2200/16 ,  B01L2300/023 ,  B01L2300/025 ,  B01L2300/04 ,  B01L2300/044 ,  B01L2300/06 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0681 ,  B01L2300/0816 ,  B01L2300/0838 ,  B01L2300/0864 ,  B01L2300/0867 ,  B01L2300/087 ,  B01L2300/12 ,  B01L2300/161 ,  B01L2300/1827 ,  B01L2400/0406 ,  B01L2400/0439 ,  B01L2400/0487 ,  B01L2400/0677 ,  B01L2400/0683 ,  B05D3/002 ,  B05D2518/00 ,  C12Q1/6825 ,  F16K99/0032 ,  F16K99/0036 ,  F16K2099/0084 ,  G01N1/02 ,  G01N21/78 ,  G01N27/28 ,  G01N27/3271 ,  G01N27/3272 ,  G01N27/3273 ,  G01N33/54306 ,  G01N33/54326 ,  G01N33/54333 ,  G01N33/54366 ,  G01N33/54373 ,  G01N33/581 ,  G01N35/00029 ,  G01N35/0098 ,  G01N35/1095 ,  G01N2001/027 ,  G01N2001/028 ,  G01N2035/00277 ,  G01N2035/00554 ,  G01N2458/30 ,  H04M1/72527 ,  Y10T137/1797

摘要： Devices, systems, and methods for detecting molecules of interest within a collected sample are described herein. In certain embodiments, self-contained sample analysis systems are disclosed, which include a reusable reader component, a disposable cartridge component, and a disposable sample collection component. The reader component may communicate with a remote computing device for the digital transmission of test protocols and test results. In various disclosed embodiments, the systems, components, and methods are configured to identify the presence, absence, and/or quantity of particular nucleic acids, proteins, or other analytes of interest, for example, in order to test for the presence of one or more pathogens or contaminants in a sample.

公开(公告)号：US09606031B2

公开(公告)日：2017-03-28

申请号：US14338976

申请日：2014-07-23

申请人： Covaris, Inc.

发明人： James A. Laugharn, Jr. ,  Guillaume Durin ,  Jonathan Sampson ,  Austin Purdy

IPC分类号： A61B10/00 ,  G01N1/30 ,  G01N1/02 ,  G01N1/31 ,  G01N1/40

CPC分类号： G01N1/30 ,  G01N1/02 ,  G01N1/31 ,  G01N2001/028 ,  G01N2001/4094

摘要： Systems and methods are described for transfer of tissue samples from a substrate to a vessel, for subsequent processing (e.g., focused acoustic treatment) within the vessel. A transfer apparatus, having a transfer end and a handle end, may be used to collect a sample material from the substrate. When the sample material is collected from the substrate, the transfer end may be placed within a vessel for treatment of the sample material while the transfer end is also located within the vessel. In some embodiments, the transfer end may be decoupled or otherwise separated from the handle end so that only the transfer end portion of the transfer apparatus is located within the vessel during treatment.

公开(公告)号：US09556577B2

公开(公告)日：2017-01-31

申请号：US14378017

申请日：2013-02-11

申请人： IHC HOLLAND IE B.V.

发明人： Pedro Vaz Viegas ,  Maria Bernardete Goncalves Castro ,  Edwin Albert Munts

IPC分类号： E02B15/10 ,  E02B15/04 ,  B63B35/32 ,  E02B15/00 ,  G01N1/02 ,  G01N1/20 ,  C02F1/00 ,  C02F103/00 ,  G01N1/10 ,  B63B1/12 ,  B63B35/00 ,  C02F103/08

CPC分类号： E02B15/10 ,  B63B35/32 ,  B63B2001/123 ,  B63B2035/007 ,  C02F1/001 ,  C02F2103/007 ,  C02F2103/08 ,  C02F2201/002 ,  C02F2201/008 ,  E02B15/00 ,  E02B15/046 ,  G01N1/02 ,  G01N1/2035 ,  G01N2001/028 ,  G01N2001/1006

摘要： An assembly for being dragged by a vessel, wherein the assembly includes a filtering system and a fluidum guiding system, wherein the filtering system is suitable for filtering large volumes of fluidum, and wherein the fluidum guiding system defines a channel configured such that at least in a channel portion the current velocity of the fluidum guided through that channel portion is reduced downstream, and wherein the fluidum guiding system and the filtering system are mutually arranged such that current velocity of fluidum filtered in the filtering system is reduced for decreasing drag.

摘要翻译： 一种用于由船只拖动的组件，其中所述组件包括过滤系统和流体引导系统，其中所述过滤系统适于过滤大体积的流体，并且其中所述流体引导系统限定通道，其被配置为使得至少在 导流通过该通道部分的流体的当前速度的通道部分被减少到下游，并且其中流体引导系统和过滤系统相互布置，使得在过滤系统中过滤的流体的流速减小以减小阻力。

公开(公告)号：US09554780B2

公开(公告)日：2017-01-31

申请号：US14002617

申请日：2012-03-01

申请人： Rui Jorge Gonçalves Pereira Nobre ,  Hugo João Marques Prazeres ,  Rui Pedro Marques Da Costa ,  Luís Carlos Gonçalves Pereira Nobre

发明人： Rui Jorge Gonçalves Pereira Nobre ,  Hugo João Marques Prazeres ,  Rui Pedro Marques Da Costa ,  Luís Carlos Gonçalves Pereira Nobre

IPC分类号： B01L3/00 ,  A61B10/02 ,  A61B10/00 ,  G01N1/02 ,  G01N1/40 ,  G01N15/06

CPC分类号： A61B10/02 ,  A61B10/0045 ,  A61B10/0096 ,  A61B2010/0087 ,  B01L3/5021 ,  B01L3/5029 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/0689 ,  B01L2300/044 ,  B01L2300/046 ,  B01L2300/0609 ,  B01L2300/0832 ,  B01L2300/087 ,  B01L2400/0409 ,  G01N1/02 ,  G01N1/40 ,  G01N15/0656 ,  G01N2001/028

摘要： The present invention refers to a portable device for the collection of biological samples. The device comprises a receptacle (8) with a cover (2), which comprises a pierceable area (3) and may include a collection instrument (1), comprising a rod (4), and a collection arrangement at the end, which may include a solid matrix, for instance a sponge or a tampon (5). The receptacle (8) has a rounded or conical shaped bottom (10), at the center of which there is a conical or rounded-shaped projection (11), with one or more holes (12). The bottom of the receptacle (8) is in contact with a collector recipient through a system of close-aperture, which may comprise screw or a fitting system with protrusions (13). In this way, the device referred in the present invention allows for the collection, storage, transportation and separation of biological material without significant manipulation and without risk of cross-contamination.

摘要翻译： 本发明涉及用于收集生物样品的便携式装置。 该装置包括具有盖（2）的容器（8），其包括可刺穿区域（3），并且可以包括收集器具（1），包括杆（4）和末端处的收集装置 包括固体基质，例如海绵或棉条（5）。 容器（8）具有圆形或圆锥形的底部（10），其中心处有一个具有一个或多个孔（12）的锥形或圆形突起（11）。 容器（8）的底部通过近孔的系统与收集器接收器接触，该系统可以包括具有突起（13）的螺钉或配件系统。 以这种方式，本发明提及的装置允许生物材料的收集，储存，运输和分离，而不会有显着的操作，并且没有交叉污染的风险。

公开(公告)号：US09534247B2

公开(公告)日：2017-01-03

申请号：US13927941

申请日：2013-06-26

申请人： Sanigen Co., Ltd.

发明人： Jeong Woong Park ,  Dong Jin Woo ,  Seong Bin Im ,  Sang Woo Kim

IPC分类号： C12Q1/24 ,  G01N1/02 ,  G02B27/18 ,  G03F7/20 ,  G09F19/18

CPC分类号： C12Q1/24 ,  G01N1/02 ,  G01N2001/028 ,  G02B27/18 ,  G03F7/70216 ,  G09F19/18

摘要： The present invention relates to an apparatus for partitioning a sampling region on a solid surface and a method for collecting a microbial sample from a solid surface, in which an optimal sampling region is partitioned on a solid surface using a light source without bringing the solid surface into direct contact with a ruler or a partitioning tool. With the apparatus and method, a solid surface can be prevented from being contaminated during partitioning process, accuracy of sampling operation can be increased, partitioning operation can be continuously performed in a simple manner, and cost of sampling operation can be reduced.

摘要翻译： 本发明涉及一种用于分割固体表面上的采样区域的装置和从固体表面收集微生物样品的方法，其中使用光源将最佳采样区域在固体表面上分隔而不使固体表面 与标尺或分割工具直接接触。 利用该装置和方法，可以防止在分割过程中固体表面被污染，可以提高采样操作的精度，能够以简单的方式连续执行分割操作，并且可以降低采样操作的成本。

公开(公告)号：US20160223440A1

公开(公告)日：2016-08-04

申请号：US15069430

申请日：2016-03-14

申请人： Abuzar Kabir ,  Kenneth G. Furton

发明人： Abuzar Kabir ,  Kenneth G. Furton

IPC分类号： G01N1/40 ,  G01N33/94 ,  B01J20/32 ,  B01J20/291 ,  B01J20/22

CPC分类号： G01N1/405 ,  B01J20/223 ,  B01J20/291 ,  B01J20/3225 ,  B01J20/3289 ,  B01J20/3295 ,  G01N1/02 ,  G01N33/94 ,  G01N2001/028

摘要： A fabric phase sorptive extractor (FPSE) is a sampling device where a flexible fabric is coated with at least one sol-gel derived film that includes at least two of a metal oxide portion, a siloxy portion, and an organic portion, where the gel has at least some amorphous portions. The FPSE is flexible such that it can be used in an extended form or draped over a solid surface to contact a gaseous, liquid, or solid environment and can be manipulated for placement in a container where the absorbed analyte can be removed from the FPSE for instrumental analysis. The FPSE can have specific functionalities that bind to specific analytes or can provide a general sorbent medium for extraction of a wide range of analytes, such that the sampling device can be employed for sampling analytes with biological, environmental, food, pharmaceutical, bio-analytical, clinical, forensic, toxicological, national security, public health, and/or safety implications.

摘要翻译： 织物相吸收萃取器（FPSE）是一种采样装置，其中柔性织物涂覆有至少一种溶胶 - 凝胶衍生的膜，其包括金属氧化物部分，甲硅烷氧基部分和有机部分中的至少两个，其中凝胶 具有至少一些非晶部分。 FPSE是柔性的，使得其可以以延伸形式使用或者覆盖在固体表面上以接触气态，液体或固体环境并且可以被操纵以放置在容器中，其中吸收的分析物可以从FPSE中去除 工具分析。 FPSE可以具有与特定分析物结合的特定功能，或者可以提供用于提取广泛分析物的通用吸附剂介质，使得采样装置可用于对具有生物，环境，食品，药物，生物分析 临床，法医，毒理学，国家安全，公共卫生和/或安全隐患。

公开(公告)号：US09370775B2

公开(公告)日：2016-06-21

申请号：US13923789

申请日：2013-06-21

申请人： GE HEALTHCARE BIO-SCIENCES CORP.

发明人： Michael A. Harvey ,  Breck Olland Parker ,  Stevan Paul Tortorella ,  Elizabeth A. Moran ,  John Pipinias

IPC分类号： B01L9/00 ,  B01L3/00 ,  G01N1/02 ,  G01N35/00

CPC分类号： B01L9/00 ,  B01L3/5023 ,  B01L3/505 ,  B01L2200/027 ,  B01L2300/069 ,  G01N1/02 ,  G01N2001/028 ,  G01N2035/00356

摘要： The field of the present invention pertains to a controlled transfer biological collection device using a dry solid storage and transfer medium and a method for the collection of biological material of interest (genetic or proteinaceous material) in a form suitable for storage and/or subsequent analysis. Specifically, the present invention provides for a sampling device that controls the transfer of the biological sample to the storage medium by holding the storage medium and a moveable sample collection member having an analyte collection surface. The invention further provides for a method not only for storing a biological analyte on this collection device but also for analyzing the stored biological analyte using methods that are suited for automated analyzing systems.

摘要翻译： 本发明的领域涉及使用干燥固体储存和转移介质的受控转移生物收集装置和用于以适于储存和/或随后分析的形式收集目的生物材料（遗传或蛋白质材料）的方法 。 具体地，本发明提供一种采样装置，其通过保持存储介质和具有分析物收集表面的可移动样品收集构件来控制生物样品向存储介质的转移。 本发明还提供了不仅用于将生物分析物储存在该收集装置上的方法，而且还用于使用适合于自动分析系统的方法分析储存的生物分析物的方法。

公开(公告)号：US20160139005A1

公开(公告)日：2016-05-19

申请号：US15007629

申请日：2016-01-27

申请人： Terry YOUNG ,  Timothy TEMPLET ,  Paul DUBE ,  Todd DIXON ,  Armand F. LEWIS ,  Yong K. KIM

发明人： Terry YOUNG ,  Timothy TEMPLET ,  Paul DUBE ,  Todd DIXON ,  Armand F. LEWIS ,  Yong K. KIM

IPC分类号： G01N1/04

CPC分类号： G01N1/04 ,  A61B10/0045 ,  A61B10/0051 ,  A61B10/007 ,  A61B2010/0067 ,  A61B2010/0074 ,  A61B2010/0216 ,  B32B37/16 ,  D01D5/36 ,  D01F8/12 ,  D01F8/14 ,  G01N1/10 ,  G01N2001/028 ,  Y10T156/10 ,  Y10T156/1043 ,  Y10T156/1089

摘要： Swabs, and materials of the present disclosure, and methods of making same, include randomly arranged sea-island bicomponent fibers which have randomly splayed terminal ends.