公开(公告)号：US20180164217A1

公开(公告)日：2018-06-14

申请号：US15835582

申请日：2017-12-08

Applicant: The Board of Trustees of the Leland Stanford Junior University

Inventor： Cristina Zavaleta ,  Michael J. Mandella ,  Zhen Qiu

IPC: G01N21/65 ,  A61B5/00 ,  A61B5/15 ,  A61K49/00

CPC classification number: G01N21/65 ,  A61B1/043 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/0084 ,  A61B5/1072 ,  A61B5/150832 ,  A61B2562/0257 ,  A61K49/0002 ,  G01N21/6456 ,  G01N21/658 ,  G01N2021/6439 ,  G01N2021/656

Abstract: The present disclosure describes a Raman topography system, which includes a container with at least one Raman probe positioned within. Also described are methods of imaging which include the Raman topography system.

公开(公告)号：US20180154129A1

公开(公告)日：2018-06-07

申请号：US15821740

申请日：2017-11-22

Applicant: ST JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC

Inventor： Saurav Paul ,  Troy T. Tegg ,  Reed R. Heimbecher ,  Richard E. Stehr ,  Riki Chou Thao

IPC: A61M39/10 ,  A61B5/06

CPC classification number: A61M39/10 ,  A61B5/0084 ,  A61B5/042 ,  A61B5/061 ,  A61B5/065 ,  A61B5/1076 ,  A61B5/6852 ,  A61B5/6885 ,  A61B18/1492 ,  A61B18/24 ,  A61B2017/00057 ,  A61B2017/00084 ,  A61B2090/065 ,  A61M25/0043 ,  A61M25/0068 ,  A61M25/0069 ,  A61M25/007 ,  A61M25/0071 ,  A61M25/0074 ,  A61M25/01 ,  A61M25/0138 ,  A61M25/0141 ,  A61M2025/0002 ,  A61M2025/0166

Abstract: A contact sensing assembly including a catheter and an electrode including a tip portion and a base portion, and a generally central axis, with the electrode being connected to a distal end of the catheter. Optical sensor(s) may be provided for emitting and/or receiving an optical signal, with a part of the optical signal being transverse to the central axis. Optical interference member(s) may be provided for interfering with the optical signal. A method for sensing contact force exerted by an electrode on a tissue includes directing an optical signal along a portion of a catheter, emitting and/or receiving an optical signal, with a part of the optical signal being at a predetermined angle relative to the central axis, and sensing changes in intensity of the optical signal based on displacement associated with the electrode tip portion based on the contact force exerted by the electrode on the tissue.

公开(公告)号：US20180153408A1

公开(公告)日：2018-06-07

申请号：US15504057

申请日：2016-05-10

Applicant: Ze Shan YAO ,  Piotr KUCHNIO ,  Michael Frank Gunter WOOD ,  Tammy Kee-Wai LEE ,  Yanhui BAI ,  Michael Peter BULK ,  Christopher Thomas JAMIESON

Inventor： Ze Shan YAO ,  Piotr KUCHNIO ,  Michael Frank Gunter WOOD ,  Tammy Kee-Wai LEE ,  Yanhui BAI ,  Michael Peter BULK ,  Christopher Thomas JAMIESON

IPC: A61B5/00 ,  A61B34/20

CPC classification number: A61B5/0075 ,  A61B5/0042 ,  A61B5/0071 ,  A61B5/0077 ,  A61B5/0082 ,  A61B5/0084 ,  A61B5/026 ,  A61B5/061 ,  A61B5/725 ,  A61B5/7425 ,  A61B5/748 ,  A61B17/34 ,  A61B34/20 ,  A61B90/20 ,  A61B90/361 ,  A61B2034/2055 ,  A61B2090/309 ,  A61B2562/0233 ,  A61B2562/0242 ,  G01J3/0248 ,  G01J3/10 ,  G01J3/2803 ,  G01J3/2823 ,  G01J2003/106 ,  G01J2003/2826

Abstract: A multispectral synchronized imaging system is provided. A multispectral light source of the system includes: blue, green and red LEDs, and one or more non-visible light sources, each being independently addressable and configured to emit, in a sequence: at least visible white light, and non-visible light in one or more given non-visible frequency ranges. The system further includes a camera and an optical filter arranged to filter light received at the camera, by: transmitting visible light from the LEDs; filter out non-visible light from the non-visible light sources; and otherwise transmit excited light emitted by a tissue sample excited by non-visible light. Images acquired by the camera are output to a display device. A control unit synchronizes acquisition of respective images at the camera for each of blue light, green light, visible white light, and excited light received at the camera, as reflected by the tissue sample.

公开(公告)号：US09980648B2

公开(公告)日：2018-05-29

申请号：US14496127

申请日：2014-09-25

Applicant: TERUMO KABUSHIKI KAISHA

Inventor： Ema Itoh ,  Isao Mori

IPC: A61B8/00 ,  A61B5/00 ,  A61B8/12 ,  A61B1/00 ,  A61B8/13 ,  G01N29/04 ,  G01N29/24 ,  A61B8/14 ,  A61B8/08

CPC classification number: A61B5/0035 ,  A61B1/00096 ,  A61B5/0066 ,  A61B5/0084 ,  A61B8/0891 ,  A61B8/12 ,  A61B8/13 ,  A61B8/14 ,  A61B8/4416 ,  A61B8/445 ,  A61B8/4461 ,  A61B8/5261 ,  G01N29/043 ,  G01N29/2418 ,  G01N2291/023 ,  G01N2291/0289

Abstract: A probe includes a transmitting and receiving unit in which an ultrasonic wave transmitting and receiving unit and a light transmitting and receiving unit are arranged. The ultrasonic wave transmitting and receiving unit and the light transmitting and receiving unit are arranged along an axial direction. A distance L [mm] between a position of the ultrasonic wave transmitting and receiving unit in the axial direction and a position of the light transmitting and receiving unit in the axial direction, and the angular difference θ [degrees] between a transmit direction of an ultrasonic wave of the ultrasonic wave transmitting and receiving unit and a transmit direction of light of the light transmitting and receiving unit satisfy a relationship of L=V/ω×θ/360 when having a rotary velocity ω [r/s] of the transmitting and receiving unit 221 and a movement velocity V [mm/s] of the transmitting and receiving unit 221 in the axial direction.

公开(公告)号：US20180132698A1

公开(公告)日：2018-05-17

申请号：US15576716

申请日：2016-05-26

Applicant: UNIVERSITÉ LAVAL

Inventor： Tigran GALSTIAN ,  Armen SAGHATELYAN ,  Arutyun BAGRAMYAN

IPC: A61B1/00 ,  A61B5/00 ,  G02F1/29 ,  G02B3/00 ,  G01N21/64

CPC classification number: A61B1/0019 ,  A61B1/00016 ,  A61B1/00032 ,  A61B1/00108 ,  A61B1/00165 ,  A61B1/04 ,  A61B1/06 ,  A61B5/0042 ,  A61B5/0068 ,  A61B5/0071 ,  A61B5/0084 ,  A61B2562/0242 ,  G01N21/6458 ,  G01N21/6486 ,  G01N2021/6419 ,  G01N2021/6441 ,  G01N2021/6478 ,  G02B3/00 ,  G02B3/0087 ,  G02B3/14 ,  G02F1/134309 ,  G02F1/13471 ,  G02F1/29 ,  G02F2001/294 ,  G02F2201/12

Abstract: There is disclosed an imaging system for use in imaging a sample. The imaging system comprising a light source and a light detector. A probe optically coupled to the imaging assembly. The probe being configured to, during use, direct light from the light source to a focal point to illuminate the sample, and from the focal point to the light detector. The probe having a tunable liquid crystal lens (TLCL) assembly comprising at least one pair of TLCLs, the TLCLs of the pair being superposed to one another, a gradient-index (GRIN) lens assembly having a base being optically connected to the TLCL assembly, and a tip opposite to the base. The focal point being at a working distance from the tip. The working distance being adjustable relative to the tip by tuning each TLCL of the TLCL assembly during use.

公开(公告)号：US09962127B2

公开(公告)日：2018-05-08

申请号：US14778380

申请日：2014-03-17

Applicant: Erasmus University Medical Center Rotterdam

Inventor： Tianshi Wang ,  Charles Theodoor Lancee ,  Antonius Franciscus Wilhelmus Van Der Steen ,  Gijs Van Soest

IPC: A61B5/02 ,  A61B5/00 ,  A61B5/0452 ,  A61B5/0205 ,  A61B5/044 ,  A61B7/00

CPC classification number: A61B5/7285 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/02007 ,  A61B5/0205 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/6852 ,  A61B5/7282 ,  A61B7/00

Abstract: A catheter-based optical imaging system for imaging a patient includes a catheter-based imaging device configured to direct optical radiation towards a vessel wall and to receive reflected radiation therefrom. A displacement mechanism is configured to vary the position of the imaging device relative to the catheter as a function of time during an imaging scan. An input is configured to receive cardiac event timing data, such as ECG data, from the patient. A trigger module is configured to initiate an imaging scan based on the cardiac event timing obtained from the cardiac event timing data. By triggering the optical imaging scans between cardiac events, artifacts in the image data can be reduced or eliminated.

公开(公告)号：US20180120212A1

公开(公告)日：2018-05-03

申请号：US15800780

申请日：2017-11-01

Applicant: Canon USA, Inc.

Inventor： Masaki Hosoda ,  Haruo Nakaji ,  Zhuo Wang

IPC: G01N11/00 ,  A61B1/07 ,  A61B1/04 ,  A61B1/00

CPC classification number: G01N11/00 ,  A61B1/00009 ,  A61B1/00147 ,  A61B1/00172 ,  A61B1/04 ,  A61B1/07 ,  A61B5/0062 ,  A61B5/0075 ,  A61B5/0084 ,  G01N2011/006

Abstract: One or more spectrally encoded endoscopy (SEE) devices, systems, methods and storage mediums for characterizing, examining and/or diagnosing, and/or measuring viscosity of, a sample or object using speckle detection are provided. Examples of such applications include imaging, evaluating and diagnosing biological objects, such as, but not limited to, for Gastro-intestinal, cardio and/or ophthalmic applications, and being obtained via one or more optical instruments. Preferably, the SEE devices, systems methods and storage mediums include or involve speckle intensity autocorrelation function(s). One or more embodiments involve a serial time-encoded 2D imaging system with speckle detection to reconstruct images, store reconstructed images of the sample or object, and/or measure viscosity of the sample or object.

公开(公告)号：US09943235B2

公开(公告)日：2018-04-17

申请号：US15418415

申请日：2017-01-27

Applicant: Volcano Corporation

Inventor： David H. Burkett

IPC: H01R24/00 ,  A61B5/0215 ,  A61B5/0205 ,  A61B8/12 ,  A61B5/00 ,  H01R13/453 ,  H01R13/631 ,  H01R13/717

CPC classification number: A61B5/02055 ,  A61B5/0035 ,  A61B5/0066 ,  A61B5/0084 ,  A61B5/0215 ,  A61B5/02158 ,  A61B8/12 ,  A61B2562/225 ,  A61B2562/227 ,  A61B2562/228 ,  H01R13/453 ,  H01R13/629 ,  H01R13/631 ,  H01R13/717 ,  H01R2201/12 ,  H01R2201/20

Abstract: Intravascular devices, systems, and methods are disclosed. In some embodiments, side-loading electrical connectors for use with intravascular devices are provided. The side-loading electrical connector has at least one electrical contact configured to interface with an electrical connector of the intravascular device. A first connection piece of the side-loading electrical connector is movable relative to a second connection piece between an open position and a closed position, wherein in the open position an elongated opening is formed between the first and second connection pieces to facilitate insertion of the electrical connector between the first and second connection pieces in a direction transverse to a longitudinal axis of the intravascular device and wherein in the closed position the at least one electrical contact is electrically coupled to the at least one electrical connector received between the first and second connection pieces.

公开(公告)号：US20180085095A1

公开(公告)日：2018-03-29

申请号：US15830640

申请日：2017-12-04

Applicant: LightLab Imaging, Inc.

Inventor： Christopher Hutchins ,  Alexander Ship

IPC: A61B8/08 ,  A61B8/00 ,  A61B8/12 ,  A61B5/00

CPC classification number: A61B8/5261 ,  A61B5/0066 ,  A61B5/0084 ,  A61B8/12 ,  A61B8/4416

Abstract: A method for bringing an IVUS and an OCT image into register. In one embodiment, the method includes obtaining an IVUS image of an area of a lumen; obtaining an OCT image of the same area of the lumen; determining the same asymmetry in each of the IVUS and OCT images; and overlaying the IVUS and OCT images and rotating them with respect to one another until the asymmetry in each of the IVUS and OCT images are in register, and determining the angle of rotation that resulted in the registration. In another aspect, the invention relates to a probe for OCT and IVUS imaging. In one embodiment, the probe includes a sheath having a first end and a second end defining a lumen; a marker that is opaque to light and ultrasound located between the first end and second end; and an IVUS/OCT probe head positioned within the sheath.

公开(公告)号：US09918669B2

公开(公告)日：2018-03-20

申请号：US14455258

申请日：2014-08-08

Applicant: Medtronic Xomed, Inc.

Inventor： Richard L. Brown ,  John G. Pollock ,  Kevin L. McFarlin ,  Randal C. Schulhauser

IPC: A61B5/04 ,  A61B5/00 ,  A61N1/36 ,  A61B5/0492 ,  A61M16/04 ,  A61B5/0205 ,  A61B1/00 ,  A61B1/267 ,  A61B5/0488 ,  A61B5/11 ,  A61B5/01 ,  A61B5/024 ,  A61B5/08

CPC classification number: A61B5/4041 ,  A61B1/00004 ,  A61B1/00016 ,  A61B1/00036 ,  A61B1/2673 ,  A61B5/0002 ,  A61B5/0004 ,  A61B5/0008 ,  A61B5/0024 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/02055 ,  A61B5/024 ,  A61B5/04012 ,  A61B5/04017 ,  A61B5/0488 ,  A61B5/0492 ,  A61B5/0816 ,  A61B5/11 ,  A61B5/1107 ,  A61B5/14539 ,  A61B5/1473 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/6833 ,  A61B5/6843 ,  A61B5/6848 ,  A61B5/6852 ,  A61B5/7475 ,  A61B2560/0209 ,  A61B2562/0209 ,  A61M16/04 ,  A61M16/0443 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/36 ,  A61M2205/502 ,  A61M2205/52 ,  A61M2205/8206 ,  A61M2230/06 ,  A61M2230/42 ,  A61M2230/50 ,  A61M2230/60 ,  A61M2230/63 ,  A61N1/36014

Abstract: A nerve integrity monitoring device includes a control module and a physical layer module. The control module is configured to generate a payload request. The payload request (i) requests a data payload from a sensor in a wireless nerve integrity monitoring network, and (ii) indicates whether a stimulation probe device is to generate a stimulation pulse. The physical layer module is configured to (i) wirelessly transmit the payload request to the sensor and the stimulation probe device, or (ii) transmit the payload request to a console interface module. The physical layer module is also configured to, in response to the payload request, (i) receive the data payload from the sensor, and (ii) receive stimulation pulse information from the stimulation probe device. The data payload includes data corresponding to an evoked response of a patient. The evoked response is generated based on the stimulation pulse.