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    Detector arrangement with rotary drive in an instrument for processing microscale liquid sample volumes
    2.
    发明授权
    Detector arrangement with rotary drive in an instrument for processing microscale liquid sample volumes 有权
    用于处理微量液体样品体积的仪器中的旋转驱动装置的检测器装置

    公开(公告)号：US07261858B2

    公开(公告)日：2007-08-28

    申请号：US10244420

    申请日：2002-09-17

    申请人： Tomas {dot over (A)}gren

    发明人： Tomas {dot over (A)}gren

    IPC分类号： B04B13/00

    CPC分类号： G01N21/253

    摘要： The invention relates to a detector arrangement in an instrument for analysis of discrete liquid sample volumes in the microliter and/or nanoliter range contained in microchannel structures that are present in a disc shaped microfluidic device. The suggested detector arrangement comprises a detector head, supported to be driven and controlled for linear displacement and positioning in a first radial plane through a central axis of an associated rotary drive. A rotary member is carried for rotation about said central axis in a second radial plane in parallelism with said first radial plane. A vacuum source is connected with the rotary member and in air flow communication with a planar top surface of the rotary member for a wide area distribution of sub-pressure over said top surface, the rotary member carrying the disc shaped substrate in adhering contact with the top surface for spinning the substrate in equidistant and equiangular relation to the detector head.

    摘要翻译： 本发明涉及一种用于分析存在于盘形微流体装置中的微通道结构中的微升和/或纳升级范围内的离散液体样品体积的仪器中的检测器装置。 所提出的检测器装置包括检测器头，被支撑为被驱动并被控制用于线性位移并且通过相关联的旋转驱动器的中心轴线定位在第一径向平面中。 承载旋转构件，以与所述第一径向平面平行的第二径向平面中的所述中心轴线旋转。 真空源与旋转构件连接并且与旋转构件的平面顶表面气流连通，用于在所述顶表面上的大范围分压的副压力，所述旋转构件承载盘形基底与所述旋转构件的粘合接触 顶部表面，用于以与待检测器头等距和等角度关系旋转衬底。

    Method of manufacturing a microscale nozzle
    3.
    发明授权
    Method of manufacturing a microscale nozzle 有权
    微型喷嘴的制造方法

    公开(公告)号：US07213339B2

    公开(公告)日：2007-05-08

    申请号：US10450177

    申请日：2001-12-12

    申请人： Per Ove Öhman ,  Per Andersson

    发明人： Per Ove Öhman ,  Per Andersson

    IPC分类号： B21D53/76

    CPC分类号： B41J2/162 ,  B41J2/1626 ,  B41J2/1631 ,  B41J2/1637 ,  B41J2/1642 ,  B41J2/1643 ,  Y10T29/49002 ,  Y10T29/49155 ,  Y10T29/49401 ,  Y10T29/4998

    摘要： Method of manufacturing a microscale nozzle, comprising the steps of forming a microscale channel in the top surface of a substrate, said microscale channel comprising an inlet end and a nozzle-end, depositing a nozzle-forming layer in a section of the microscale channel, and removing material from the substrate at the nozzle-end of the microscale channel to expose at least a portion of said nozzle-forming layer. The manufactured microscale nozzle may be used for transferring a liquid sample form a microchip fluidic system into an external analytical device.

    摘要翻译： 制造微型喷嘴的方法，包括以下步骤：在基材的顶表面形成微细通道，所述微细通道包括入口端和喷嘴端，在微细通道的一部分中沉积喷嘴形成层， 以及在所述微细通道的喷嘴端处从所述基板移除材料以暴露所述喷嘴形成层的至少一部分。 制造的微型喷嘴可用于将液体样品从微芯片流体系统转移到外部分析装置中。

    Separation structure
    8.
    发明授权
    Separation structure 有权

    公开(公告)号：US07833478B2

    公开(公告)日：2010-11-16

    申请号：US11871614

    申请日：2007-10-12

    申请人： Per Andersson ,  Gunnar Ekstrand ,  Gerald Jesson

    发明人： Per Andersson ,  Gunnar Ekstrand ,  Gerald Jesson

    IPC分类号： G01N9/30 ,  G01N33/00 ,  F16K17/36

    摘要： A centrifugal-based microfluidic device (1) that comprises a hydrophilic microchannel structure (2) in which there is a A) a separation microcavity I (4) that comprises i) a liquid inlet I (5), and ii) a liquid outlet I (6) that is at a level below the level of liquid inlet I (5) and above the level of the bottom (8) of the microcavity (4) thereby defining a lower part (4b) and an upper part (4a) of the microcavity (4), and B) a microconduit I (17) that has an inlet end I (16) directly connected to liquid outlet I (6), and an outlet end I (18) that is at a lower level than inlet end I (6). A capillary valve I (24) is associated with microconduit I (17). The flow direction through liquid outlet I (6) is directed upwards and/or liquid outlet I (6) is placed in a downwardly turned part of an inner wall of the separation microcavity (4), and/or the part of microconduit I (17) next to liquid outlet I (6) is directed upwards.

    CONTACT HEATING ARRANGEMENT
    9.
    发明申请
    CONTACT HEATING ARRANGEMENT 审中-公开
    联系加热装置

    公开(公告)号：US20090050620A1

    公开(公告)日：2009-02-26

    申请号：US10585442

    申请日：2005-01-05

    申请人： Per Andersson ,  Gunnar Kylberg

    发明人： Per Andersson ,  Gunnar Kylberg

    IPC分类号： B01L7/00 ,  B04B15/02

    CPC分类号： B01L7/52 ,  B01L3/5085 ,  B01L9/527 ,  B01L2300/0803 ,  B01L2300/0819 ,  B01L2300/1827 ,  B01L2300/1844 ,  H05B3/26 ,  H05B2203/013 ,  H05B2203/014 ,  H05B2203/021 ,  H05B2203/032

    摘要： A heating arrangement for heating one or more liquid-containing microcavities (102) that are present on a microdevice (101) in which there is a contact surface (Sdev) (108). The arrangement comprises a heating support (104,204) that has: a) a support contact surface (Ssup) (110) which is apposed to Sdev (108), when the microdevice (101) is placed on the heating support (104,204), and b) one or more heating elements (120,220) each of which are in thermal contact with Ssup (110), and also with at least one of said microcavities (102), when the microdevice (101) is placed according to (a) with said microcavities (102) matched to said heating elements (120,220), The characteristic feature of the arrangement is that it comprises a sub pressure system (113-119) that is capable of creating sub pressure between said support (104,204) and said microdevice (101) via the support when the microdevice (101) is placed on the support (104,204).

    摘要翻译： 一种用于加热存在于其中存在接触表面（Sdev）（108）的微器件（101）上的一个或多个含液体微腔（102）的加热装置。 该装置包括加热支撑件（104,204），其具有：a）当微型装置（101）放置在加热支架（104,204）上时，该支撑接触表面（Ssup）（110）安装在Sdev（108）上，以及 b）一个或多个加热元件（120,220），每个加热元件（120,220）与Ssup（110）热接触，并且还与至少一个所述微腔（102），当微型设备（101）根据（a）与 所述微腔（102）与所述加热元件（120,220）匹配。该装置的特征在于其包括能够在所述支撑件（104,204）和所述微型装置（104,204）之间产生副压力的副压力系统（113-119） 当微型装置（101）被放置在支撑件（104,204）上时通过支撑件。